• Title/Summary/Keyword: Converting

Search Result 2,601, Processing Time 0.035 seconds

Isolation of Angiotensin Converting Enzyme Inhibitory Component from the Seeds of Xanthium strumarium (창이자(蒼耳子)로부터 안지오텐신 전환효소 억제 유효 성분의 분리)

  • Lee, Yun-Mi;Kang, Dae-Gill;Kim, Myung-Gyu;Jang, Ji-Yeon;Lee, Ho-Sub
    • Journal of Physiology & Pathology in Korean Medicine
    • /
    • v.19 no.1
    • /
    • pp.119-123
    • /
    • 2005
  • In the courses of in vitro screening for the angiotensin converting enzyme (ACE) inhibitory activity of the various extracts from medicinal plants, n-BuOH soluble extract of the seeds of Xanthium strumarium was found to exhibit distinctive angiotensin converting enzyme (ACE) inhibitory activity. Bioassay-guided fractionation and purification of the n-BuOH soluble extract of the seeds of Xanthium strumarium afforded a new $xanthiazone-11-{\beta}-glucopyranoside$. The ACE activity was significantly inhibited by the addition of a new $xanthiazone-11-{\beta}-glucopyranosidein$ a dose-dependent manner of which $IC_{50}$ value was $21.8\;{\mu}g/ml$.

Luminescence Property of ZnS:Mn,Mg Phosphor with Excitation of Plasma Blue Light Source

  • Ryu, Si Hong;Kim, Wan Kyu;Lee, Seong Eui
    • Transactions on Electrical and Electronic Materials
    • /
    • v.14 no.1
    • /
    • pp.24-27
    • /
    • 2013
  • In this paper, we investigated the effect of luminescence properties of various concentrations of magnesium-doped ZnS:Mn phosphor excited by plasma luminescence device. The PL intensity was evaluated in the range of 300~500 nm excitation wavelengths. We found the highest PL intensity of the phosphors excited by 365 nm and 450 nm was observed at Mg concentrations of 1.4 wt% and 0.8 wt%, respectively. In addition, an emission peak was distinguished at 580 nm wavelength. With increasing Mg dopant level, enhanced PL intensity was observed, which is possibly applicable to color converting materials by blue emission for white light sources. Finally, we evaluated the luminance properties of color converting ZnS:Mn,Mg phosphors with plasma blue light source. the white luminance of plasma light source with CIE(0.36,0.26) was established by color converting phosphors of ZnS:Mn with 0.8 wt% Mg.

Hydrogen Detecting Characteristics of the $WO_3$ Films Using the R/V Converting Circuit (저항-전압변환회로를 이용한 $WO_3$ 박막의 수소검지 특성 측정)

  • Rhie, Dong-Hee;Koh, Jung-Hyuk;Kim, Young-Hwan;Sung, Yung-Kwon
    • Proceedings of the KIEE Conference
    • /
    • 1998.11c
    • /
    • pp.767-769
    • /
    • 1998
  • Using the R/V converting circuit, hydrogen detecting characteristics of the $WO_3$ films were investigated. The R/V converting circuit is configured with the equivalently constant current driving method connecting an unknown resistor to be measured in the feedback loop of the or-amr rather than using a separated constant current circuit. The response time of the reference voltage for the R/V converting circuit was simulated by the circuit simulator "SABER", and it was found that the response time in the high resistance range become longer and the error amounts to 10%. From the simulation results. replacing the capacitor in the feedback loop of the second stage or-amp with a 0.001uF capacitor, when measuring in the high resistance range, the response characteristics are remarkably improved. The response time was shortened from about 10 seconds to below 1 second. Using this circuit, the effect of $WO_3$ films deposited by sputtering method on hydrogen was measured.

  • PDF

A Study on Developing Traffic Data Converting Algorithm for FM DARC (FM DARC용 교통정보 변환알고리즘 개발)

  • Lee, Bong-Gyu
    • Journal of Korea Spatial Information System Society
    • /
    • v.2 no.2 s.4
    • /
    • pp.39-48
    • /
    • 2000
  • The purpose of this study is to develop a converting algorithm for providing real-time traffic information through the FM DARC(DAta Radio Channel). The converting algorithm based on the GIS node-link system enables raw traffic data to be a standard traffic information. The standard traffic information in data quality, quantity and format is an essential to construct the FM DARC traffic information system effectively. We have developed the algorithm and applied it to the FM DARC system. After introducing FM DARC briefly, this paper presents GIS DB, the converting algorithm and the client/server FM DARC system.

  • PDF

Properties of Angiotensin I-Converting Enzyme Activity in the Rice Eel, Monoptevus albus (드렁허리(Monopterus albus)의 Angiotensin I-Converting Enzyme의 특성에 관하여)

  • 김성주;이금영;조경우
    • The Korean Journal of Zoology
    • /
    • v.34 no.2
    • /
    • pp.142-147
    • /
    • 1991
  • Angiotensin I-converting enzyme (ACE) activity has been characterized in the rice eel, Monopterus albus. Peak activity of ACE in plasma from the rice eel was shown at around pH 10, which was more alkaline compared to that of mammals. Chloride requirements for the optimal ACE activity were different from species to spedes. ACE inhibitors, EDTA, teprotide (SQ 20, 881), and captopril (SQ 14, 225) showed dose-dependent inhibitions of ACE activity in plasma from the rice eel as well as mammals. ACE activity in the rice eel was increased by CoCI2, and the enzyme activity was more unstable at high temperature as compared to mammals The highest activity of ACE among the various tissues in the rice eel was found in the brain.

  • PDF

The expression of interleukin-1β converting enzyme in experimental autoimmune encephalomyelitis (자기면역성 뇌척수염에서 interleukin-1β converting enzyme의 발현)

  • Moon, Chang-jong;Kim, Seung-joon;Lee, Yong-duk;Shin, Tae-kyun
    • Korean Journal of Veterinary Research
    • /
    • v.39 no.3
    • /
    • pp.538-544
    • /
    • 1999
  • To elucidate the involvement of interleukin-$1{\beta}$ converting enzyme (ICE) in the course of experimental autoimmune encephalomyelitis (EAE), we induced EAE by immunizing rats with an emulsion of rat spinal cord homogenate with complete Freund's adjuvant supplemented with Mycobacterium tuberculosis (H37Ra, 5mg/ml) and then examined the expression of ICE in the spinal cord of rats with EAE. In normal rat spinal cords, ICE is constitutively, but weakly, expressed in ependymal cells, neurons, and some neuroglial cells. In EAE, many inflammatory cells are positive for ICE, and the majority of ICE+ cells were identified as ED1+ macrophages. During this stage of EAE, the number of ICE+ cells in brain cells, including neurons and astrocytes, increased and these cells also had increased ICE immunoreactivity. These findings suggest that the upregulation of ICE in both brain cells and invading hematogenous cells is stimulated by a secretory product from inflammatory cells, and that this enzyme is involved in the pathogenesis of EAE via the production of IL-1 beta.

  • PDF

Substrate Specificity of Mouse Glandular Kallikreins, Epidermal Growth Factor-Binding Protein Type A, B, and c against Mouse Ren 2 Prorenin (생쥐 선상칼리크레인(상피세포증식인자 결합단백질 Type A, B, 그리고 C)의 Ren 2 Prorenin에 대한 기질특이성)

  • 김화선;이희섭전병훈김원신
    • The Korean Journal of Zoology
    • /
    • v.39 no.2
    • /
    • pp.215-222
    • /
    • 1996
  • In the previous studies, we have demonstrated that prorenin converting enzyme (PRECE) was identical to the epidermal grouch factor-binding protein (EGF-BP) type B, which was a member of the mouse glandular kallikrein family, To examine whether or not EGF-BP type A and C are involved in the processing of prorenin, we have cloned the CDNAS of the EGF-BP type h and C from a library of male ICR mouse submandibular gland (SMGI. And then CHO cells were transfected with the EGF-BP expression plasmids. and stable cell lines expressing a high level of the EGF-BPS precursor were obtained. The conditioned medium was then treated with trypsin, which has been knotvn to effectively convert the EGF-BP type A and C precursor to the active forms. 수ubsequentlv, the prorenin converting activity of the trypsin-treated or untreated medium was examined. PRECE converted exactly prorenin to renin, but the prorenin converting activities of EGF-BP type A and C were not detected. From these results, it seems that only type B of these EGF-BPs is involved in processing Ren 2 prorenin in mouse SMG.

  • PDF

Effects of Captopril on the Active Angiotensin Converting Enzyme at the Pulmonary Endothelial Cells (Captopril에 의한 폐동맥 내피세포중 활성형 Angiotensin 전환효소의 변화)

  • 안형수
    • YAKHAK HOEJI
    • /
    • v.37 no.1
    • /
    • pp.41-48
    • /
    • 1993
  • The effect of captopril on the lung angiotensin converting enzyme (ACE) was investigated after 3 weeks oral administration (120~160 mg/kg/day) through drinking water in SpragueDawley rats. On the $^{125}$I-351A, an ACE inhibitor, binding assay in the isolated perpused lungs, the number of ACE molecules at the intrapulmonary endothelial cell surface was significantly decreased (p<0.001), and recovered to the normal level 7 days after discontinuation of captopril treatment. Intrapulmonary conversion ratio of Al to All was also significantly decreased (p<0.05) in the isolated perpused lungs. Bolus intravenous injection of angiotensin I did not showed pressor response in the both of systemic and pulmonary blood pressure of the anesthetized rats. ACE activity of the lung homogenates was also significantly reduced. These data consistently indicate the decrease of functionally active ACE molecule at the pulmonary artery after chronic captopril treatment. However, serum ACE activity was increased three fold in captopril treated rats compared to the normal rats. So, these results suggest that the functionally active ACE molecule at the pulmonary artery was still inhibited, which is directly associated with the antihypertensive effects, even if the total angiotensn converting enzyme induction was resulted after chronic captopril treatment.

  • PDF

Adjustable Influence of the Converting Cost in Customer Satisfaction and Customer Preference Affected by the Main Factors of Airline Services (항공서비스요인이 고객만족과 고객애호도에 미치는 영향에 대한 전환비용의 조절적 효과)

  • Chung, Yang-MI;Lee, MI-Hye
    • Journal of Advanced Navigation Technology
    • /
    • v.16 no.6
    • /
    • pp.1065-1079
    • /
    • 2012
  • This research is done with the objectives to examine and to identify how the main factors of airline services, which become fundamentals for airline customers to select their favorite one, affect their customer satisfaction and their customer preference, with a focus on adjustable influence of converting cost. The survey has been conducted with the population of the airline customers who use international airlines through Incheon International Airport and processed with the objectives to verify the influence of the main factors of airline services to customer satisfaction and customer preference and also to collect the verified data for adjustable influence of converting cost between customer satisfaction and customer preference, and its results are as follows: Firstly, airline services have significant impact on their customer satisfaction. Secondly, they also have significant impact on their customer preference, Thirdly, the converting cost between both of customer satisfaction and customer preference to airline services doesn't involve the adjustable function in consecutive cost nor in learning cost but it does involve the one in sunk cost.

Protocol converting method for the Real-time Safety Supervision System in Railway (실시간 철도안전 관제를 위한 프로토콜 변환 방안 연구)

  • Ahn, Jin;Kim, Sung-Min
    • Journal of the Korea Institute of Information and Communication Engineering
    • /
    • v.20 no.7
    • /
    • pp.1335-1341
    • /
    • 2016
  • For the safety of train operation, monitoring & supervisory systems for train, signal, power, communication and facilities is operating independently in another place, so, its sensors are interdependently connected from each other to transfer gathering datas of sensing to control center. A Goal of Real-time railway safety supervision system is to improve the safety oversight efficiency and to prevent accidents by means of hazard prediction based on big data by integrating all of safety sensing data in wayside of railway, and the System is requested acquisition of all of sensing data of safety. So, we need special method of protocol converting for the purpose of integrating all of detecting data concerning safety without any changing application. In this paper we investigate the existing converting method in communication field, and propose a new progress to converting protocol adding function of transfer using XML file, and implemented this algorithm, and tested with example packets, finally.