• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.19 no.2
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• pp.25-40
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• 2019

Many companies are executing big data analysis and utilization projects to legitimize the development of new business areas or conversion of management or technical strategies. In Korea and abroad, however, such projects are failing because they are not completed within specified deadlines, which is not unrelated to the current situation in which the knowledge base for big data project risk management from an engineering perspective is grossly lacking. As such, the current study analyzes the risk factors of big data implementation and utilization projects, in addition to finding risk factors that are highly important. To achieve this end, the study extracts project risk factors via literature review, after which they are grouped using affinity methodology and sifted through expert surveys. The deduced risk factors are structuralize using factor analysis to develop a table that categorizes various types of big data project risk factors. The current study is significant that in it provides a basis for developing basic control indicators related to risk identification, risk assessment, and risk analysis. The findings from the study contribute greatly to the success of big data projects, by providing theoretical basis regarding efficient big data project risk management.

• Journal of Korean Home Economics Education Association
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• v.35 no.2
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• pp.1-20
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• 2023

The purpose of this study is to extract and analyze ecological citizenship elements in the middle school home economics textbook used in the 2015 national curriculum for the introduction of ecological transformation education in the 2022 national curriculum. As a result of the analysis, the content analysis of the ecological citizenship factor was validated by six experts who are incumbent middle school home economics teachers, and the S-CVI value was 0.97, ensuring the validity of the ecological citizenship factor analysis. The results of analyzing 242 ecological citizenship factors extracted from home economics textbooks are as follows. According to the content area of the 2015 national home economics curriculum, the 'human development and family' area had the highest presence of ecological citizenship factors followed by the 'resource management and self-reliance' area and the 'home life and safety' area. Among the categories of ecological citizenship factors, 'value⋅attitude' was the most frequent, followed by 'process⋅function' and 'knowledge⋅understanding'. For each textbook composition system, ecological citizenship elements were extracted in the order of pictures, text, activities, and supplementary materials. There was a significant variation in the number of ecological citizenship factors among publishers, indicating the importance of the textbook writers' perception, interpretation, and direction of writing. Based on these analysis results, ecological citizenship teaching and learning activities applicable to home economics education were presented. This study highlights the potential for practicing ecological citizenship education in line with the new orientation of the curriculum on ecological transformation education through home economics education. Furthermore, it provides valuable baseline data for the development and implementation of textbooks for the 2022 national curriculum.

• International Journal of Stem Cells
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• v.16 no.2
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• pp.215-233
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• 2023

Background and Objectives: MYC, also known as an oncogenic reprogramming factor, is a multifunctional transcription factor that maintains induced pluripotent stem cells (iPSCs). Although MYC is frequently upregulated in various cancers and is correlated with a poor prognosis, MYC is downregulated and correlated with a good prognosis in lung adenocarcinoma. MYC and two other MYC family genes, MYCN and MYCL, have similar structures and could contribute to tumorigenic conversion both in vitro and in vivo. Methods and Results: We systematically investigated whether MYC family genes act as prognostic factors in various human cancers. We first evaluated alterations in the expression of MYC family genes in various cancers using the Oncomine and The Cancer Genome Atlas (TCGA) database and their mutation and copy number alterations using the TCGA database with cBioPortal. Then, we investigated the association between the expression of MYC family genes and the prognosis of cancer patients using various prognosis databases. Multivariate analysis also confirmed that co-expression of MYC/MYCL/MYCN was significantly associated with the prognosis of lung, gastric, liver, and breast cancers. Conclusions: Taken together, our results demonstrate that the MYC family can function not only as an oncogene but also as a tumor suppressor gene in various cancers, which could be used to develop a novel approach to cancer treatment.

• Korean Security Journal
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• no.22
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• pp.231-258
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• 2010

A study apartment house inhabitants of to, crime prevention effort is done satisfaction analysis and that deduce design plan of CPTED that can overcome safe life space embodiment and criminal fear from crime in Juminin viewpoint through atomize group's interaction by background fantast. Is positive because factor analysis wave and satisfaction index of deduce universe (Total group) 8 factor are presented more than all 0, and quite was expose by level that is worth accommodating. Satisfaction index of The secondary design group (Group1) 8 factor is positive because is presented more than all 0, and mechanical access control, mechanical surveillance is level that is worth accommodating quite, and level that is proper in remainder 6 dimension appear. Can know that 1 The secondary design group(Group2) is expose by level that satisfaction characteristic of 8 factor can be presented more than all 0 and appeared positively, and accommodate quite in all dimensions. Result that analyze Two-way ANOVA satisfaction difference of environment design of group by satisfaction of the primary and the secondary design group is high in 8 all dimensions of CPTED, and satisfaction by appeared satisfaction high in group less than natural access control, 2 years of natural surveillance, and reciprocal action effect that go with group is high satisfaction in 2 years low in The secondary design group more than the primary and the secondary design group of systematic access control and natural access control, and the primary and the secondary design group appeared high in subgroup of 2 remainders. Satisfaction difference by group by crime prevention effort satisfaction of the primary and the secondary design group is high in 8 all dimensions of CPTED, and satisfaction difference by crime prevention effort appeared satisfaction high in 'A prize' group to The secondary design group, and reciprocal action efficiency is high in 'A prize' group in The secondary design group more than the primary and the secondary design group in mechanical access control, systematic access control, natural access control, territoriality reinforcement, and satisfaction of 'Between' and 'Very' group appeared high in the primary and the secondary design group.

• Journal of Life Science
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• v.33 no.11
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• pp.887-896
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• 2023

The inflammatory response have been considered as one of important targets for cancer treatment because they play a key role during all steps of tumor development including initiation, promotion, malignant conversion and progression. To investigate the anti-inflammatory response during anti-tumor activity of an aqueous extracts of Ecklonia cava (AEC), alterations on the distribution of mast cells and the expression of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2), nuclear factor (NF)-κB, inflammasome compositional protein and inflammatory cytokines were examined in CT26 colon tumor-bearing BALB/cKorl syngeneic mice after administrating AEC for five weeks. After treatment of AEC, total weight of tumor and necrotic region of tumor section were significantly decreased compared to vehicle treated group. The number of infiltered mast cells was higher in AEC treated group than vehicle treated group, while the expression levels of COX-2 and iNOS were decreased in AEC treated group. Also, similar decrease pattern were detected in the expression levels of NF-κB, NLR family pyrin domain containing 3 (NLRP3), apoptosis-associated speck-like protein containing a caspase recruitment domain (ASC) and caspase-1 (Cas-1) after AEC treatment although the decrease rate was varied. Furthermore, the mRNA expressions of three inflammatory cytokines including tumor necrosis factor-α (TNF-α), interleukin-1α (IL-1α) and interleukin-6 (IL-6) were remarkably decreased in AEC treated group compared to vehicle treated group. These results suggest that inhibition of inflammatory response may be tightly associated with anti-tumor activity of AEC in CT26 colon tumor-bearing BALB/cKorl syngeneic mice.

• Korean Journal of Poultry Science
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• v.40 no.2
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• pp.121-127
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• 2013

This work was carried to evaluate production efficiency factor, carcass yield and meat quality with weeks of Large-type Korean native ducks. Korean native ducks (n = 90) from National Institute of Animal Science (RDA, Korea) were used in this work. Ninety ducks were divided into 6 groups (15 birds/group) and were fed with meat-type duck diets for 8 wk old. When ducks grew at specific wk (6, 7 and 8 weeks), 2 ducks per group were slaughtered at 6, 7 and 8 wk old. Production efficiency factor, carcass yield, partial meat and meat quality were researched in this work. There was no significant difference on livability with weeks, but body weight at 7 and 8 wk old was higher than that at 6 wk old (P<0.05). Feed conversion ratio at 6, 7 and 8 wk old were 2.25, 2.69 and 3.21, respectively, so there was significant difference with weeks (P<0.05). Production efficiency factor at 6, 7 and 8 wk old were 256.6, 199.8 and 153.0, respectively, so there was significant difference with weeks (P<0.05). Carcass yield at 8 wk old was higher than that at 6 and 7 wk old as 73.5% (P<0.05). Lightness at 6, 7 and 8 wk were 41.8, 39.0 and 38.1, respectively, and that at 6 wk old was the higher than other weeks (P<0.05). There was no significant difference on redness at 6, 7, and 8 wk old (P>0.05) and yellowness at 8 wk old was higher compared to other weeks (P<0.05). Cooking loss was the highest at 6 wk old as 31.6%, but water holding capacity was the highest at 8 wk old (P<0.05). There was no significant difference on shear force among weeks. pH at 6 wk old was the lower than that of other weeks as 5.84. Moisture content significantly decreased with weeks (P<0.05) and fat content at 8 wk was the highest as 1.88% (P<0.05). Protein content significantly increased with weeks until 20.9% at the age of 8 wk (P<0.05). Ash content at 7 and 8 wk old was the higher than that at 6 wk old (P<0.05). There was no significant difference on juiciness, tenderness, and flavor with weeks. Finally, these results may provide that shipping time at 7 wk old preferred to that at 6 and 7 wk old, but further research was needed because of deficiency of data.

• Journal of Animal Science and Technology
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• v.48 no.1
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• pp.21-28
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• 2006

A polymorphism was found in the promoter region of porcine adipocyte fatty acid binding protein gene(A-FABP) gene which plays a key role in the binding and transportation of free fatty acid in adipocyte and deposition of intramuscular fat. Mutation was detected a substitution(T406C) using SSCP analysis and subsequently confirmed by sequencing the fragment in Duroc pigs. This T-406C mutation might change the binding activity for transcription factor nuclear factor 1(NF1). In this population, this mutation was genotyped using HinfⅠRFLP, and found three kinds of genotypes(TT, TC, and CC) showing their frequencies of 42.3, 44.3, and 13.4%, respectively. We statistically analyzed the association between the A-FABP genotypes and growth traits and found that the body weights of the pigs containing 406C/(TC or CC) were heavier for the body weight at the age of 20 weeks than those containing genotype TT(P<0.05), but not for those at the age of 0, 3, and 10 weeks. Pigs containing genotype CC had also a higher value for the average daily gain and lower values for the date for 90kg of body weight and food conversion ratio than those of 406T/- genotype. In addition, without the significant difference of back fat thickness, there was a significant association between the existence of allele CC and lean meat and eye muscle area(P<0.05). As a result of this study, we suggest that the allele T406C in the promoter region of A-FABP gene play an important role in deposition of intramuscular fat and weight in the later growth period. This polymorphism will be an useful molecular marker for breeding of Duroc pigs.

• Journal of Animal Environmental Science
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• v.18 no.1
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• pp.45-56
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• 2012

This study was conducted to give basic information of the animal manure management by manure units determination for recycling farming in Cheorwon-gun. Manure units (MU) are used in the permitting, registration, and the environmental process because they allow equal standards for all animals based on manure nutrient production. An MU is calculated by multiplying the number of animals by manure unit factor for the specific type of animal. The manure unit factor for MU determination was determined by dividing amounts of manure N produced 80 kg N/year. Conversion to manure units is a procedure used to determine nutrient pollution equivalents among the different animal types. In this study, the manure unit factor based on nitrogen in Hanwoo, dairy cow, pig were 0.36, 0.8 0.105, respectively. The analysis of manure unit per ha shows that the N loading by MU is quite different by region. The nitrogen loading of manure unit (MU) per ha of cultivated land was the highest in the Galmal-eup on province with 2.4 MU/ha, which is higher than the appropriate level. The Seo-myeon province came next with 1.92 MU/ha. To be utilized as a valid program to build the recycling farming system, diverse measures shall be mapped out to properly determine manure units, evaluate N-loading and to properly manage their nutrient balance of each region.

• Journal of Korean Society of Environmental Engineers
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• v.35 no.3
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• pp.179-191
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• 2013

This study was conducted to comparatively assess quantitative indicating factor for biomineralization characterizing $CO_2$ mineralization on three type of minerals (i.e., $CaCl_2$, $MgCl_2$, $CaCl_2-MgCl_2$) in an aqueous solution amended with Bacillus pasteurii or indigenous microorganisms for a S landfill cover soil. For given three types of minerals, $NH_4{^+}$ (urease activity) was released at the highest of 88 mg/L for $MgCl_2$, then 85 mg/L for $CaCl_2$, and the lowest of 42 mg/L for $CaCl_2-MgCl_2$. $CO_2$ gas in the head space was completely removed after 12, 12, and 24 hr for $CaCl_2$, $MgCl_2$ and $CaCl_2-MgCl_2$, respectively. $Ca^{2+}$ concentration in $CaCl_2$ solution was the quickest and the greatest decreased 92% for 12 hr whereas that in $CaCl_2-MgCl_2$ solution was lower at 85% for 36 hr. $Mg^{2+}$ concentration in $MgCl_2$ was more efficiently decreased at 46% for 48 hr than that of $CaCl_2-MgCl_2$ solution of 38.5% for 72 hr. Regardless of types of minerals or their concentration, pH was changed from 5.5 to 9 by biomineralization being progressed. Microbial activity ($OD_{600}$) was also changed from 0 to 0.6. SEM images indicated that spheroidal and trapezoid shape crystal were formed, which were identified as of $CaCO_3$ (Calcite) and $MgCO_3$ (Magnesite) by X-ray diffraction. In the long run, $NH_4{^+}$ (urease activity), $CO_2$ gas, $OD_{600}$, pH, $Ca^{2+}$ and $Mg^{2+}$ would be suitable for reasonable indicating factor in order to assess the degree of biomineralization efficiency.

• Korean Journal of Poultry Science
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• v.40 no.1
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• pp.41-47
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• 2013

This work was carried out to investigate performance and carcass yield of large-type broiler females at different stocking densities. Chicks (n = 492; 1-day-old; female; Arbor Acre broiler) were reared for six weeks (starter, 0~1 wk; earlier, 1~3 wk; finisher, 3~6 wk) and randomly divided into 3 treatments (4 replications/treatment, 36, 41 or 46 birds/replication). Treatments were T1 (10.9 birds/$m^2$), T2 (12.4 birds/$m^2$) and T3 (13.9 birds/$m^2$) by the stocking densities. Research indexes were livability, body weight, body weight gain, feed intake, feed conversion ratio, production efficiency factor, carcass yield and primal cuts ratio (wing, leg, back, breast and neck). Livability (%) was 90% or more for all treatments, but there was no significant difference on weekly livability (%). Body weight of T3 treatment were the lowest at 3 wk and body weight gain, feed intake, and feed conversion ratio were the lowest at 2~3 wk (P<0.05). Production efficiency factors of T1, T2 and T3 were 331.0, 340.8 and 336.0, respectively, and there was no significant difference among treatments. Leg meat ratio of T2 treatment was higher compared to other treatments at the age of 4 wk (P<0.05). Carcass yield of T1 treatment was the highest as 76.2% at the age of 5 wk (P<0.05). However, there was no significant difference on carcass ratio and partial meat ratio among treatments at the age of 6 wk. This result may provide the standard data of different stocking densities for heavy female broilers.