• 대한한의학회지
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• 제29권1호
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• pp.1-6
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• 2008

Objective : To investigate the therapeutic effect of manual acupuncture at Siguan (four gates, bilateral LI4 and LR3) on suppression of gastrointestinal motility. Methods : A single blind, randomized, sham-acupuncture controlled, crossover study was conducted. Twenty healthy male subjects were admitted at hospital, and gastrointestinal motility suppression was induced by loperamide administration. Just after intake of 20 radio-markers, four gates or sham acupoint treatments were administered every 12 hours, 4 times over 48 hours. Gastrointestinal motility was evaluated by radiographic distribution of the radiomarkers at stomach or ileum, ascending, transverse, descending colon, sigmoid/rectum, and outside body at serial time points (0, 6, 12, 24, and 48 h). Results : Four gates acupuncture activated gastrointestinal movement as evidenced by significantly changed distributionof radio-makers at 6, 12, and 48 hours (P < 0.0001, P = 0.001, and P = 0.03, respectively) in Cochran-Mantel-Haenszel statistics. No serious adverse events occurred in either group. Conclusions : This study showed a scientific clinical relevance of four gates acupuncture to gastrointestinal disorders.

• 동의신경정신과학회지
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• 제27권4호
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• pp.261-274
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• 2016

Objectives: To determine the general characteristics of clinical studies about Hwabyung and assess their limitations and alternatives. Methods: Clinical studies that examined the effects of traditional Korean medicine intervention on Hwabyung were included in this study. A systematic search of English, Chinese, Japanese, and Korean databases was performed. The characteristics of included articles were described and those articles were assessed by Risk of Bias (RoB) tool or Risk of Bias for Nonrandomized Studies (RoBANS) tool. Results: Sixteen articles were selected from 1,826 articles. Most clinical studies about Hwabyung were published in Korea. The number of conducted trials was insufficient. The prevailing study design was randomized controlled trial. Traditional Korean medicine intervention used in the trials were acupuncture, herbal medicine, counselling, meditation, emotional freedom technique (EFT), music therapy, art therapy, and multi intervention program. Herbal medicine study used placebo as control while non-pharmacological intervention study mostly used no treatment as control. Most of the trials were supported by the government. Therefore, financial conflict of interest might not exist for results. We judged that some studies had a high risk of bias. In general, most of the studies with a high risk of bias were non-pharmacological intervention studies, and the risk of bias was mainly due to lack of blinding. Conclusions: More clinical studies of Hwabyung are needed. There are some issues about a suitable comparison and effective blinding strategy for non-pharmacological study. Improving methodological quality is required.

• 대한물리치료과학회지
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• 제26권3호
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• pp.23-36
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• 2019

Background: The purpose of this study was to investigate the effect of Plank exercise on unstable support surfaces on flexibility, abdominal muscle thickness and pain in patients with chronic back pain. Design: Randomized controlled trial. Methods: This study was performed on 16 patients with chronic back pain of ◯◯ military unit. Sixteen subjects were randomly assigned into two groups, an upper extremity trainer group (group I, n=8) and a lower extremity trainer group (group II, n=8). The subjects in group I carried out Flank exercise applying the stability trainer to their upper extremities and ones in group II carried out the same exercise applying the stability trainer to their lower extremities for 4 weeks. In order to ascertain the difference between two groups, flexibility, abdominal muscle thickness and pain were measured before and after the exercise. The flexibility was measured by sit and reach test, the thickness of the abdominal muscle was measured by using ultrasonic imaging equipment, and the pain was measured by the visual analogue scale. A paired t-test was utilized to compare changes in pain, abdominal muscle thickness and flexibility before and after flank exercise on unstable support surfaces. Analysis of Covariance (ANCOVA) was performed for ascertaining the significant differences between groups. The significance level was set by α=.05. Results: 1) The flexibilities of two groups were increased after the exercise (p<0.05). 2) In both groups, the thicknesses of rectus abdominis, external oblique abdominis, internal oblique abdominis, and transverse abdominis were all increased after the exercise (p<0.05). 3) The pains in both groups were decreased after the exercise (p<0.05). 4) In the comparisons of two groups, there were no differences in the flexibility, thickness of external oblique abdominis, internal oblique abdominis and transverse abdominis and pain (p>0.05). Whereas only thickness of Rectus abdominis was larger in the group I than in the group II (p<0.05). Conclusion: Plank exercise on the unstable support surface for 4 weeks resulted in increased flexibility, abdominal muscle thickness and pain reduction in patients with chronic back pain. Therefore, it is considered that performing flank exercise on the unstable supporting surface is suitable for the reduction of the pain in patients with chronic back pain. However, in this study, it is considered that continuous and diverse studies are needed because there was not a large difference between the groups when the upper or lower limbs are provided unstable support surfaces.

• 대한한의학회지
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• 제29권2호
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• pp.165-181
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• 2008

Objectives: This study was conducted to help clinical studies for treating the common cold with Oriental medicine. We inspected tendencies of clinical studies of the common cold in western medicine and analyzed the assessing instruments for it by scrutinizing PubMed publications for the last five years. Materials and Methods: We inspected 32 theses and scrutinized their objectives, periods, participants, materials and methods, the instrument of assessment for the studies, and validity, reliability, criteria and symptom score for questionnaires, results and JADAD score. Results: 1. The median for total period of study was 7 months, the median for days of treatment was 7.5, and most studies were carried out during the winter/spring period, because of the enhanced risk of cold infections. 2. The studies focused on unorthodox medicines or new drug products, such as antipyretic analgesics (e.g. paracetamol), decongestant and bronchodilator (e.g. ephedrine), echinacea, antioxidants (e.g. zinc), probiotic bacteria and so on. 3. All theses except one had subjectscomposed of cold patients who were infected naturally. The median number of subjects for final analysis was 187. 4. 27 studies used survey as the instrument of assessment. Among these, only one thesis was verified for validity. 5. The mean of JADAD score was 4.41, suggesting most of theses of worth. 7 studies were assessed as ineffective. Conclusion: Recent studies of the common cold are focused on unorthodox medicines or new drug products, and it is necessary to provide an objective instrument for assessing common cold treatments.

• 한국콘텐츠학회논문지
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• 제17권2호
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• pp.687-695
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• 2017

본 연구는 청소년의 음주폐해 예방을 위한 학교기반, 피드백, 행동수정의 3가지 중재 중 음주 빈도와 문제행동의 감소에 효과적인 중재를 확인하고자 하였다. 청소년기 그룹에게 알코올 중재를 적용한 무작위대조군연구 16편을 대상으로 메타분석을 수행하였다. 학교기반, 피드백, 행동수정의 각 중재방법에 따른 음주빈도와 음주 문제행동을 추적기간별로 나누어 통계적 이질성, 효과크기, 민감도 검정을 실시하였다. 음주빈도의 감소를 위한 결과 피드백 중재가 3개월 미만에서, 음주 문제행동의 감소를 위한 결과 피드백 중재가 4~12개월의 추적기간에서 유의미한 차이를 보였다(p<.05). 음주 빈도의 결과 3개월 미만에서 학교기반이 "큰", 피드백은 "작은", 4~12개월에서는 피드백이 "큰" 효과크기로 해석되었다. 음주 문제행동의 결과 3개월 미만에서 학교기반이 "중간", 피드백은 "큰", 4~12개월에서는 학교기반이 "중간", 피드백은 "큰" 효과크기로 해석되었다. 피드백 중재가 3개월 미만의 추적기간 동안 음주 빈도의 감소를 위해 효과적이며, 4~12개월의 추적기간 동안에는 음주 문제행동 감소에 효과적인 중재임을 확인하였다. 또한 청소년의 음주폐해 감소 및 예방을 위한 학교기반 중재와 피드백 중재의 유용성을 확인하였다.

• Asian Pacific Journal of Cancer Prevention
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• 제14권12호
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• pp.7229-7235
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• 2013

Background: To determine whether the Health Partner Program is effective in training long-term cancer survivors to be health coaches. Materials and Methods: We randomly assigned cancer survivors who were selected through a rigorous screening process to either the Health Partner Program or the waiting-list control group. The program consisted of 8 weeks of training in health management, leadership, and coaching. At baseline, 8, and 16 weeks, we measured primary outcomes using the Seven Habit Profile (SHP), the Korean Leadership Coaching Competency Inventory (KCCI), Ed Diner's Satisfaction with Life Scale (SWLS), and the Posttraumatic Growth inventory (PTGI) and secondary outcomes using the Hospital Anxiety and Depression Scale (HADS), the Impact of Event Scale-Revised (IES-R), and the Medical Outcomes Study (MOS) short form 36-item questionnaire (SF-36). Results: We recruited 70 subjects and randomly assigned 34 to the intervention group. The Sharpen the Saw habit of the SHP increased significantly more in intervention group than in the control group (p=0.049), as did most PTGI factors. The intervention group also showed a significantly greater enhancement of vitality (p=0.015) and mental health (p=0.049) SF-36 scores but no improvement in KCCI, SWLS, HADS, or IES-R scores. The intervention group also showed a greater clinically meaningful improvement in the "Think Win-Win" of SHP (p=0.043) and in the personal strength score (p=0.025) and total score (p=0.015) of the PTGI. Conclusions: Long-term cancer survivors can benefit from the Health Partner Program to become health coaches.

• 대한관절경학회지
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• 제14권1호
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• pp.13-19
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• 2010

목적: 전방십자인대 재건술에 있어서 이중다발과 재건술과 단일다발 재건술의 임상적 결과 및 방사선학적 결과에 대한 전향적 연구를 수행하고자 하였다. 대상 및 방법: 연구는 편측 무릎의 전방십자인대 손상이 있는 56명의 환자군(group T)을 모집하여 27명은 이중다발 재건술군으로 배정하였으며(group D), 29명은 단일다발 재건술군으로 배정하였다(group S). 두 비교군 간의 임상적인 수술 결과는 최소 2년간의 추적 관찰 기간 내 Lysholm knee score, Tegner activity score, Lachman & pivot shift test와 영상 검사(슬관절 전후방 부하 X선 촬영검사)를 통하여 비교 분석하였다. 결과: 술후 2년 추적 관찰에서의 Lysholm knee score, Tegner activity score 수치에서, 두 비교군 사이에 유의한 임상적 차이를 보이지 않았다(p>0.05). Lachman test, pivot shift test와 영상 검사 결과상에서도 두 비교군 사이에 유의한 차이점이 밝혀지지 않았다(p>0.05). 결론: 이중다발 전방십자인대 재건술은 최소 2년간의 추적 관찰에서, 단일다발 재건술에 비해 임상적 결과나, 수술 후 영상 검사 상에서의 우월함을 보이지 못하였다. 이는 전방십자인대 손상 환자들에서 전내측 다발 재건술만으로도 우수한 임상적 결과가 나올 수 있음을 시사한다.

• 정신신체의학
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• 제12권2호
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• pp.135-144
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• 2004

연구목적 : 본 연구의 목적은 기공에 기초한 스트레스 관리 프로그램이 산모의 우울, 불안 등의 정서에 미치는 영향에 대하여 알아보고자 하였다. 방법: 임신 16주 이상의 산모들을 대상으로 하였다. 기공프로그램군은 8주동안, 일주일에 2번씩 기공프로그램에 참여한 52명으로 구성되었으며, 교육군은 8주동안 1주일에 1번씩 산모교육에 참여한 40명으로 구성되었다. 평가도구는 우울 수준을 측정하는 척도로서 해밀턴 우울 척도(Hamilton depression rating scale, HAMD), 벡 우울 척도(Beck depression inventory, BDI), 에딘버러 산후 우울증 척도(Edinburgh postnatal depression scale, EPDS)를 이용하였다. 불안 수준을 측정하는 척도로서 스필버거 특성 상태 불안척도-1 (Spielberger trait state anxiety inventory-1, STAI-1), 해밀턴 불안 척도(Hamilton anxiety scale, HAM-A)를 이용하였다. 기공과 교육 프로그램 시작전, 이후 2주, 4주, 8주에 걸쳐 산모의 우울, 불안 수준을 상기 척도로 측정하였다. 결과: 기공프로그램군은 프로그램 시작 전과 8주 후를 비교하였을 때 유의미하게 불안과 우울 수준이 모든 척도에서 호전되었다. 반면 교육군은 시작 전과 8주 후를 비교하였을 때 유의미한 호전은 없었다. 두 집단의 프로그램 전후 변화량을 비교한 결과 기공프로그램군이 교육군에 비하여 통계적으로 유의미한 변화를 보였다. 결론: 본 연구는 기공에 기초한 스트레스 관리 프로그램이 산모의 불안과 우울감을 조절하는데 효과적인 방법일 수 있음을 시사한다.

• 대한약침학회지
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• 제11권1호
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• pp.55-69
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• 2008

Objective : We investigated the effects of distilled Wild Ginseng Herbal Acupuncture on autonomic nervous system with the Heart Rate Variability(HRV) in adult man. as well as we tried to observe how distilled Wild Ginseng Herbal Acupuncture on the balance of the autonomic nervous system. Method : We investigated the effects of distilled Wild Ginseng Herbal Acupuncture on autonomic nervous system with the Heart Rate Variability(HRV) in adult man. as well as we tried to observe how distilled Wild Ginseng Herbal Acupuncture on the balance of the autonomic nervous system. 1 healthy volunteers consisted of 31 subjects in experiment(distilled Wild Ginseng Herbal Acupuncture) group and 30 subjects in control(Normal Saline) group. Study form was a randomized, placebo-controlled, double-blind clinical trial. 31 subjects in experiment group were injected distilled Wild Ginseng Herbal Acupuncture at $GB_{21}$(Kyonjong) and 30 subjects in control group were injected Normal Saline at $GB_{21}$(Kyonjong). except of 2 subjects(in control group) who can't be measured and 11 subjects(7 in experiment group and 4 in control group) who move or make unforceable error during measuring. Finally 24 subject in experiment group and 24 subject in control group are studied. We measured HRV by PolyG-I on 7 times : before and after injection per 5 minutes during 30 minutes. The SPSS 10.0 for windows was used to analyze the data and the paired t-test(in group) and Student t-test(between two groups) were used to verify the result. Result : 1. After distilled Wild Ginseng Herbal Acupuncture injection, Mean HRV is significantly low only for first 5 minute, SDNN is significantly high after 5 minute, Complexity is significantly low after 5 minute, HRV index is significantly high after 10 minute and pNN50 is significantly low after 5 minute. 2. SDNN of distilled Wild Ginseng Herbal Acupuncture Group significantly increased from 20minute to 25minute, and pNN50 of distilled Wild Ginseng Herbal Acupuncture Group significantly decreased from 10minute to 15minute and 20 minute to 30 minute compared with those of Normal Saline group. 3. After distilled Wild Ginseng Herbal Acupuncture injection, Ln(TP), Ln(VLF) and Ln(LF) are significantly high after 5 minute, normalized LF is significantly high after 5 minute and normalized HF is significantly low after 5 minute. 4. Ln(TP) and Ln(VLF) of distilled Wild Ginseng Herbal Acupuncture Group significantly increased from 20minute to 25 minute compared with those of Normal Saline group. Conclusion : The results suggest that distilled Wild Ginseng Herbal Acupuncture in healthy adult man tend to activate the autonomic nervous system and sympathetic nervous system compared to Normal Saline within normal range.

• Journal of Nutrition and Health
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• 제40권8호
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• pp.708-718
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• 2007

본 연구는 비타민 E의 보충섭취가 폐경기 여성의 항산화 영양상태 및 임파구 DNA 손상을 개선할 수 있는지를 알아보고자 수행되었으며, 이중맹검법으로 실시되었고 플라시보를 위약군으로 하였다. 폐경기 여성 35명을 대상으로 6주 동안 비타민 E 보충섭취군에게는 비타민 E 캡슐($\alpha$-tocopherol 성분 400 IU/capsule)을, 위약군에게는 대두유로 만든 위약 캡슐(400 mg/capsule)을 하루 2회 섭취하도록 하였으며, 이 때 두 군의 분류는 무작위로 하였다. 항산화 영양상태를 알아보기 위해 혈장 vitamin C, $\alpha$-tocopherol, $\gamma$-tocopherol, $\alpha$-carotenoid, $\beta$-carotenoid, lycopene 농도를 측정하였고, 임파구 DNA 손상정도를 알아보기 위해서는 Comet assay를 이용하여 tail length, %DNA in tail, tail moment를 측정하였다. 비타민 E 보충섭취군에서는 혈장 vitamin C(p<0.05)와 $\alpha$-tocopherol(p<0.000)농도가 유의적으로 증가하였고, $\gamma$-tocopherol(p<0.000) 농도와 tail length(p<0.05)는 유의적으로 감소하였다. 반면, 위약군에서는 혈장 vitamin C(p<0.05)의 농도만이 유의적으로 증가하였다. 결론적으로, 본 연구는 비타민 E의 보충섭취가 혈장 항산화 상태 및 DNA 손상에 대해 부분적인 개선 효과가 있음을 보여주었다.