• 한국소음진동공학회:학술대회논문집
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• 한국소음진동공학회 2002년도 추계학술대회논문집
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• pp.1015-1021
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• 2002

Optical disk is the media which is used generally in data storage device, but it has a disadvantage in the vibration by spinning and the shock. For overcoming these disadvantage, we must control the optical disk to minimize the focusing error and tacking error. The present study investigates the disk profile for minimizing the focusing error subjected to environmental shock and weight of the disk. In this study, the disk is assumed to be a cantilever beam to determine the disk profile for the minimum displacement as to the shock considering only the first mode. Also, for the optimally determined profile by ADS program this paper recalculate the robust caltilever profile by using orthogonal array and ANOM.

• 대한기계학회:학술대회논문집
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• 대한기계학회 2001년도 추계학술대회논문집B
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• pp.634-639
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• 2001

The current study addresses experimental and computational work of impulse wave discharged from the exit of two kinds of right-angle pipe bends, which are attached to the open end of a simple shock tube. The weak normal shock wave with its magnitude of Mach number from 1.02 to 1.20 is employed to obtain the impulse wave propagating outside the exit of the pipe bends. A Schlieren optical system visualizes the impulse wave discharged from the exit of the pipe bends at an instant. The experimental data of the magnitude of the impulse wave and its propagating directivity are analyzed to characterize the impulse waves discharged from the exit of the pipe bends and compared with those discharged from a straight pipe. Computational results well predict the experimented dynamic behaviors of the impulse wave. The results obtained show that a right-angle miter bend considerably reduces the magnitude of the impulse wave and its directivity toward to the pipe axis, compared with the straight pipe and right-angle smooth bend. It is believed that the right-angle miter bend pipe can playa role of a passive control against the impulse wave.

• Journal of Periodontal and Implant Science
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• 제35권1호
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• pp.1-8
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• 2005

Bacterial heat shock protein has been one of the components that are responsible to induce autoimmune disease mechanisms in the pathogenesis of atherosclerosis due to high level of homology in sequence with human counterpart. This mechanism may explain how bacterial infectious disease, such as periodontal disease, might contribute to the acceleration of the disease process of atherosclerosis. Porphyromonas gingivalis which is a major periodontal pathogenic bacterial species, has been implicated as one of the pathogenic bacteria playing the role in this context. The present study has been performed to evaluate the anti-atherosclerotic effect of adoptive transfer of Porphyromonas gingivalis heat shock protein epitope-specific T cell lines into severe combined immunodeficiency (SCID) mice. Peptide no. 15 with amino acid sequence VKEVASKTND-specific T cell line was selected for the transfer. When experimental atherosclerosis was induced in SCID mice adoptively transferred either by the T cell lines (experimental group) or by non-specific mouse T cells (control group), there was no significant difference in the severity and extent of the atherosclerosis induced by hypercholesterol diet.

• Journal of Microbiology and Biotechnology
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• 제23권2호
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• pp.149-155
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• 2013

Heterologous expression of a putative $K^+/H^+$ antiporter of Streptomyces coelicolor A3(2) (designated as sha4) in E. coli and Streptomyces hygroscopicus JCM4427 showed enhanced tolerance to $K^+$ stress, acidic-pH shock, and/or geldanamycin production under $K^+$ stress. In a series of $K^+$ extrusion experiments with sha4-carrying E. coli deficient in the $K^+/H^+$ antiporter, a restoration of impaired $K^+$ extrusion activity was observed. Based on this, it was concluded that sha4 was a true $K^+/H^+$ antiporter. In different sets of experiments, the sha4-carrying E. coli showed significantly improved tolerances to $K^+$ stresses and acidic-pH shock, whereas sha4-carrying S. hygroscopicus showed an improvement in $K^+$ stress tolerance only. The sha4-carrying S. hygroscopicus showed much higher geldanamycin productivity than the control under $K^+$ stress condition. In another set of experiments with a production medium, the secretion of geldanamycin was also significantly enhanced by the expression of sha4.

• 약학회지
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• 제39권3호
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• pp.231-242
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• 1995

Electroconvulsive shock (ECS) increases the activity of acetylchohnesterase and decreases in brain acetylcholine levels. A large amount of free fatty acids accumulated in the brain tissue affects cerebral blood flow, brain edema and inflammation and results in brain injury. The present study examined the effect of docosahexaenoic acid (DHA) and D,L-pyroglutamic acid (D,L-PCA) on the learning and memory deficit using the passive avoidance failure technique and on the change of acetylcholine and choline level in the cerebral cortex of ECS-induced mice. The application of ECS (25mA, 0.5sec) induced a significant decrease in memory function for 30 min. ECS-induced a significant decrease in cortical acetylcholine and choline levels 1 min following the ECS application, which were almost recovered to ECS control level after 30 min. DHA (20 mg/kg, i.p.). administered 24 hr before shock. prevented the ECS-induced passive avoidance failure and the decrease of acetylcholine level 1 min following the ECS application. DHA failed to elicit a change in cortical choline level. DHA did not affect memory function and the cortical Ach and choline level of normal mice. The administration of D,L-PCA (500 mg/kg, i.p.) increased the effect of DHA on memory function and the change of cortical acetylcholine level of ECS induced mice. These results suggest that DHA treatment may be contributed to the prevention against memory deficit, and to the activation of cholinergic system in the ECS induced mice.

• Advances in aircraft and spacecraft science
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• 제8권1호
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• pp.53-67
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• 2021

The increasing interest in the exploration of Mars stimulated the authors to study aerodynamic problems linked to space vehicles. The aim of this paper is to evaluate the aerodynamic effects of a flapped wing in collaborating with parachutes and retro-rockets to reduce velocity and with thrusters to control the spacecraft attitude. 3-D computations on a preliminary configuration of a blunt-cylinder, provided with flapped fins, quantified the beneficial influence of the fins. The present paper is focused on Aerodynamics of a wing section (NACA-0010) provided with a trailing edge flap. The influence of the flap deflection was evaluated by the increments of aerodynamic force and leading edge pitching moment coefficients with respect to the coefficients in clean configuration. The study was carried out by means of two Direct Simulation Monte Carlo (DSMC) codes (DS2V/3V solving 2-D/3-D flow fields, respectively). A DSMC code is indispensable to simulate complex flow fields on a wing generated by Shock Wave-Shock Wave Interaction (SWSWI) due to the flap deflection. The flap angle has to be a compromise between the aerodynamic effectiveness and the increases of aerodynamic load and heat flux on the wing section lower surface.

• 한국소음진동공학회:학술대회논문집
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• 한국소음진동공학회 2007년도 추계학술대회논문집
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• pp.1266-1271
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• 2007

General coil spring has linearity. However, disc spring has non-linearity so that using this non-linearity disc spring can be designed to do shock-absorbing in cases we need because shock response also has non-linearity. By changing the shape and stacking number, it is satisfactory with response of displacement, velocity and acceleration. Conventionally, disc spring was used to control the vibration against huge load and limited space. However, it is limitedly used because of difficulty of the designing guidance. Therefore, disc spring is needed to study further in order to apply it widely. Response of disc spring is compared to response of coil spring by changing ho/t radio with computer simulation and the usage of disc spring is increased through analysis of effect of design factors. The purpose of this paper is that the shock response of disc spring is calculated through numerical simulation and effect of ho/t and stiffness is analyzed to broad usage so that design factor of disc spring is presented.

• 한국IT서비스학회지
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• 제16권2호
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• pp.129-138
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• 2017

This paper is concerned with an Internet of Things (IoT)-based unmanned home-delivery box system, in which the system is developed with a prototype using a weight sensor, shock sensor, the Arduino and Raspberry-Pi of open-source hardware platforms. The developed system provides several functions such as a safe storage means, prevention of delivery-theft, and remote control of the home-delivery box, etc. Specifically, the system recognizes the arrival of goods by detecting the weight of deliveries and sends the arrived message of deliveries to the recipient' smartphone, and also controls (i.e., open and close) the locker of the unmanned home-delivery box system remotely with the smartphone. Furthermore, the developed system provides automatically a warning alarm around the unmanned home-delivery box when an external shock is applied to the home-delivery box, and sends a message on the shock to the recipient' smartphone. The major functions of the developed home-delivery box system have been verified in a realistic environment, and confirmed to work well. With the application of the developed home-delivery box system to the homes and offices where recipients are always not to stay, it is expected to significantly improve the safety of delivered goods as well as to effectively prevent the delivery operatives posing as a crime.

• 한국소음진동공학회논문집
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• 제18권2호
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• pp.153-159
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• 2008

General coil spring has linearity. However, disc spring has non-linearity so that using this non-linearity disc spring can be designed to do shock-absorbing in cases we need because shock response also has non-linearity. By changing the shape and stacking number, it is satisfactory with response of displacement, velocity and acceleration. Conventionally, disc spring was used to control the vibration against huge load and limited space. However, it is limitedly used because of difficulty of the designing guidance. Therefore, disc spring is needed to study further in order to apply it widely. Response of disc spring is compared to response of coil spring by changing $h_o/t$ ratio with computer simulation and the usage of disc spring is increased through analysis of effect of design factors. The purpose of this paper is that the shock response of disc spring is calculated through numerical simulation and effect of $h_o/t$ and stiffness is analyzed to broad usage so that design factor of disc spring is presented.

• 한국소음진동공학회논문집
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• 제11권9호
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• pp.406-413
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• 2001

The current study depicts and experimental work of the impulsive wave discharged from the exit of several kinds of right-angle bend pipes, which are attached to the open end of a simple shock tube. The weak normal shock wave with Mach number from 1.02 to 1.20 is employed to obtain the impulsive wave propagating outside the exit of the pipe bends. The experimental data of the magnitude of the impulsive wave and its propagation directivity are analyzed to characterize the impulsive waves discharged from the right-angle bend pipes and compared with those from a straight pipe. The impulsive waves are visualized by a Schlieren optical system. A computation work using the two-dimensional, unsteady, compressible Euler equation is also carried out to represent the experimented impulsive waves. The results obtained show that a right-angle miter bend considerably reduces the magnitude of the impulsive wave and its directivity toward to the pipe axis, compared with the straight pipe. It is believed that the right angle miter bend pipe can play a role of passive control agianst the impulsive wave.