• Korean Journal of Food Science and Technology
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• v.29 no.1
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• pp.167-172
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• 1997

Effect of combined preparation (DWP715) containing Alaska pollack extract, maltol, ascorbic acid and nicotinamide on decreasing of blood alcohol was evaluated in human blood. Treatment of DWP715 prior to administration of 25% alcohol (100 mL) decreased alcohol concentration in blood and showed significant difference after 2 hours. The pharmacokinetic parameters such as area under the concentration-time curve (AUC), $C_{max},\;T_{max}\;and\;T_{1/2}$ were also decreased and delayed when compared with control values. Effects of DWP715 on anti-fatigue and anti-oxidation activities were also studied in the restraint stress model using various parameters (GOT, GPT, LDH values and organ weights) on mild condition and examined through the content of lipid peroxide induced by 2% $CCl_4$ in mouse livers. While GPT level, thymus and adrenal weight were not influenced by DWP715 dosing, LDH, GOT level and spleen weight used as a parameter against fatigue and stress states were recovered almost to the nomal level. Furthermore, lipid peroxidation due to $CCl_4$ was significantly inhibited by DWP715 treatment. These results suggest that DWP715 seems to metabolize the blood alcohol rapidly and to restore the damaged liver and fatigue conditions which was caused by alcohol metabolism to normal condition.

• Journal of Korea Water Resources Association
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• v.44 no.7
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• pp.553-563
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• 2011

According to the improvement of computer's performance, the development of Geographic Information System (GIS), and the activation of offering information, a distributed model for analyzing runoff has been studied a lot in recently years. The distribution model is a theoretical and physical model computing runoff as making target basin subdivided parted. In the distributed model developed by this study, the volume of runoff at the surface flow is calculated on the basis of the parameter determined by landcover data and a two-dimensional diffusion wave equation. Most of existing runoff models compute velocity and discharge of flow by applying Manning-Strickler's mean velocity equation and Manning's roughness coefficient. Manning's roughness coefficient is not matched with dimension and ambiguous at computation; Nevertheless, it is widely used in because of its convenience for use. In order to improve those problems, this study developed the runoff model by applying not only Manning-Strickler's equation but also Chezy's mean velocity equation. Furthermore, this study introduced a power law of exponential friction factor expressed by the function of roughness height. The distributed model developed in this study is applied to 6 events of fan-shape basin, oblong shape test basin and Anseongcheon basin as real field conditions. As a result the model is found to be excellent in comparison with the exiting runoff models using for practical engineering application.

• Proceedings of the Korean Society of Applied Pharmacology
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• 1994.04a
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• pp.243-243
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• 1994

Although active systemic anaphylaxis and passive cutaneous anaphylaxis have been empolyed to study anaphylactic hypersensitivity, it is difficult and time-consuming to induce these reactions in experimental animals. In recent, Jun et al have found a simple method to induced anaphylactic hypersensitivity such as anaphylactic shock(AS) and cutaneous reaction(CR) using compound48/80. Cortex mori (Morus alba L.), the root bark of mulberry tree has been used as an antiphlogistic, diuretic, and expectorant in herbal medicine. The purpose of this study was to determine whether the methanol extract of Cortex mori could inhibit the compound 48/80-induced AS and CR. To induce AS, various doses of compound 48/80 (5, 7.5, 10, 15$\mu\textrm{g}$/gm B.W.) were injected intraperitoneally (i.p.) into ICR mice. The animals were pretreated by three injection(i.p.) of Cortex mori before compound 48/80 administration. Peripheral blood was collected from the right ventricle to estimate the level of serum histamine at 15 minutes after the injctin(i.p.) of various concentration of compound48/80. Mortility rate, mean death time and mesenteric mast cell degranulation rate were evaluated over a 72 hour period. To estimate the effect of Cortex mori on compound 48/80-induced cutaneous reaction, various doses of compound 48/80 with or without Cortex mori were injected intradermally(i.d.) into the shaved flank of Sprague-Dawley rats, and the blue cutaneous patchs induced by Evans'blue injection at the compound 48/80 alone and Cortex mori plus compound 48/80 injection sites were observed. As a Parameter of these reactions, the levels of histamine in the supernatant, calcium uptake and intracellular CAMP of RPMC were measured. supernatant, 1)compound 48/80-induced mortility rate, mean death time, mesenteric mast cell degranulation rate, and serum histamine level in ICR mice were significantly inhibited by pretreatment of Cortex mori, 2) cutaneous reaction inducd by compound48/80 was well developed in Sprague-Dawley rat, but Cortex mori inhibited the compound 48/80-induced blue patch formation remarkably, 3) the compound 48/80-induced degranulation, histamine release and calcium uptake of RPMC pretreated with Cortex mori were significantly inhibited, compared to those of control without Cortex mori pretreatment, and 4)the level of cAMP of RPMC was reduced bythe increased concentration of compound 48/80, pretreatment of Cortex mori not only inhibited the compound 48/80-induced reduction of CAMP but also significantly increased the level of cAMP naturally, from the above results, it is suggested that Cortex mori has an some substances with an ability to inhibits the compound 48/80-induced AS,CR, and mast cell activation.

• Journal of the Korea Concrete Institute
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• v.24 no.1
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• pp.3-14
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• 2012

This paper describes experimental results on the seismic performance of SHCC (strain-hardening cement composite) infill wall for improving damage tolerance capacity of non-ductile frame. To investigate the effect of tensile strain capacity and cracking behavior of SHCC materials on the shear behavior of SHCC infill wall, three infill walls were fabricated and tested under cyclic loading. The test parameter in this study is a type of cement composites; concrete and SHCCs. The two types of SHCC materials were prepared for infill walls. In order to induce crack damages into the mid-span of the infill wall, each infill wall had two 100-mm-deep-notches on both sides. Test results indicated that SHCC infill walls showed superior crack control capacities and much larger drift ratios at the peak loads than RC (reinforced concrete) infill wall, as expected. In particular, due to the bridging actions of the reinforcing fibers, SHCC matrix used in this study would delay the stiffness degradation of infill wall after the first inclined cracking. Moreover, from the damage classes based on the cracks' maximum width in the infill walls, it was observed that PIW-SHD specimen possessed nearly threefold seismic capacities compared to PIW-SLD specimen. Also, from the results on the strain of diagonal reinforcements, it can be concluded that the SHCC matrix would resist a part of tensile stresses transferred along steel rebar in the infill wall.

• Journal of the Korean Society for Advanced Composite Structures
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• v.3 no.1
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• pp.8-15
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• 2012

The initial clamping forces of high strength bolts depending on different faying surface conditions drop within 1,000 hours regardless of loading, any other external force or loosening of the nut. This study is focused on an expectation model for relaxation of high strength bolt, which is confined to creep on coated faying surfaces after initial clamping. The range of this experiment is limited to estimate the relaxation of bolted joints coated by inorganic zinc primer. The candidate bolts were dacro-coated tension control bolts. The parameters of coated thickness for the faying surface were 96, 168,and $226{\mu}m$ respectively. From experiments, it exhibited that the logarithmic function for creep strain was derived due to the parameter of coating thickness. By using the creep strain, subsequently the quantitative model for estimating long term relaxation of high strength bolt can be taken with the elapsed time. The experimental results showed that the relaxation after the initial clamping of high strength bolt rose to a much higher range from 10% to 18% due to creep of the coating as the coating thickness was increased. This study showed that the clamping force reflecting relaxation after the elapse of constant time can be calculated from the initial clamping force of high strength bolt.

• Tunnel and Underground Space
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• v.28 no.2
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• pp.156-169
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• 2018

The relationship between the mechanical and textural properties of sedimentary rocks has been studied for decades. However, inconsistencies in the results have arisen from both the inhomogeneity of natural rocks and the difficulties encountered in controlling just one textural factor of interest in each experiment. This work produced artificial sedimentary rocks to enable control of every independent parameter at all times. Their homogeneity lowered the deviation of the results, and thus they produced clearer correlations than for natural rocks. The samples were made by mixing bassanite powder with water and silica sand, which produced rocks consisting of sand and gypsum cement. The effect of grain content and size on mechanical properties such as uniaxial compressive strength, Young's modulus, and seismic velocity was estimated. Increasing grain content lowered the compressive strength but raised Young's modulus and seismic velocity. Overall, grain size did not linearly affect the mechanical properties of the samples, but affected them in some way. In future, these results can be compared and integrated with similar experiments using different cement or grain types. This should allow comparison of the effects of the rock constituents themselves and their interactions, with applicability to all kinds of sedimentary rocks.

• Journal of radiological science and technology
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• v.31 no.2
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• pp.177-182
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• 2008

Digital imaging for general rediography has many advantages over the film/screen systems, including a wider dynamic range and the ability to manipulate the images produced. The wider range means that acceptable images may by acquired at a range of dose levels, and therefore repeat exposures can be reduced. Digital imaging can result in the over use of radiation, however, because there is a tendency can be reduced. Digital imaging can result in the over use of radiation, however, because there is a tendency for images to be acquired at too high a dose. We investigated the actual exposure dose conditions on general radiography and a questionnaire survey was conducted with radiotechnologiest at medical institutions using digital radiology system. As a results, the dose of exposure was not controlled with patient's figure and dose optimization but was controlled by worker's convenience and image quality. Radio-technologiests often set up the exposure dose regardless of patient figure and body part to be examined. Many organizations, such as the International Commission on Radiological Protection, recommend to keep the dose as low as possible. In addition, they strongly recommend to keep the optimal but minimal dosage by proper training programs and constant quality control, including frequent patient dose evaluations and education.

• Journal of Korean Society of Transportation
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• v.34 no.3
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• pp.278-290
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• 2016

Maximum traffic flow rate is an important performance measure of operational status in transport networks, and has been considered as a key parameter for transportation operation since a bottleneck in congestion decreases maximum traffic flow rate. Although previous studies for traffic flow analysis have been widely conducted, a detection method for changes in dynamic traffic flow has been still veiled. This paper explores the dynamic traffic flow detection that can be utilized for various traffic operational strategies. Turning point analysis (TPA), as a statistical method, is applied to detect the changes in traffic flow rate. In TPA, Bayesian approach is employed and vehicle arrival is assumed to follow Poisson distribution. To examine the performance of the TPA method, traffic flow data from Jayuro urban expressway were obtained and applied. We propose a novel methodology to detect turning points of dynamic traffic flow in real time using TPA. The results showed that the turning points identified in real-time detected the changes in traffic flow rate. We expect that the proposed methodology has wide application in traffic operation systems such as ramp-metering and variable lane control.

• Horticultural Science & Technology
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• v.28 no.6
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• pp.1066-1071
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• 2010

To evaluate the effect of horticultural therapy (HT) on the emotional improvement of depressed patients, computer-based heart rate variability (HRV) was compared with self-report scale (SRS) known as existing subjective evaluation method. SRS included four test areas: mental stress scale (MSS), physical stress scale (PSS), Beck anxiety inventory (BAI), and Beck depression inventory (BDI). HRV was itemized into four parameters: standard deviation of the N-N intervals (SDNN), square root of mean squared difference of successive N-N intervals (RMSSD), total power (TP), and low-frequency/high-frequency ratio (LF/HF ratio). Thirty patients with depression at the same mental hospital participated in this study. 15 patients of the treatment group received HT once a week for three months, but the control group did not during the same period. As a result, the emotional improvement in treatment group was clearly identified through HRV as well as SRS. The significant difference was shown at three test areas (MSS, BAI, and BDI, $p$ < 0.001) in SRS and at one parameter (total power, $p$ < 0.05) in HRV. There was noticeable increase in SDNN, RMSSD, and LF/HF ratio in treatment group after HT activity, but no significant difference. Although all parameters of HRV did not show significance, the possibility of HRV as an objective evaluation method to HT was recognized in this study. These results also implied that HT was efficient in the mental and physical regeneration of the depressed patients in both subjective and objective evaluation methods.

• Journal of Animal Science and Technology
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• v.45 no.4
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• pp.607-616
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• 2003

This study was conducted to determine the effect of feeding a total mixed ration(TMR) of broiler litter(BL) and bakery by-product(BB) with additional BL or rice straw incorporated at 10% of dietary DM as a roughage source on behavior pattern, nutrient intake, digestibility, digestible nutrient intake, ruminal and blood parameters, and N balance of sheep. All the treatment diets were formulated to be isoenergetic[total digestible nutrients(TDN) 66.9%]. Compared with the conventional formulated feed - rice straw feeding system(control), feeding TMR with BL(T1) or rice straw(T2) at 10% of dietary DM resulted in reduced eating, ruminating and total chewing time(P<0.05), similar DM intake, low(P<0.05) digestible DM, OM, fiber and total nutrients intake, low(P<0.05) nutrients digestibilities except EE, similar ruminal characteristics(pH, VFA concentrations and ratios, efficiency of carbohydrate fermentation, NH3-N), and favorable N digestion and retention. There were no differences in the above parameters between T1 and T2 with the exception of increased(P<0.05) eating, ruminating and total chewing time for T2. These results suggested that a TMR of BL and BB with or without rice straw may replace the conventional formulated feed and rice straw in ruminant diets successfully and furthermore feeding the TMR with rice straw made sheep behavior pattern more favorable.