• 사상체질의학회지
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• 제29권3호
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• pp.232-241
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• 2017

Objectives This study was to identify the lifestyle associated with metabolic syndrome and to suggest a personalized health management according to the constitution to prevent disease by metabolic syndrome stage. Methods This study used the data of Korean medicine Data Center (KDC). A total of 8,985 data were searched for subjects who participated in Anseong and Ansan cohorts study from 2009 to 2012. We analyzed 2,602 participants that diagnosed with metabolic syndrome among the ages of 30 to 55. We divided into three groups, none, pre-metabolic syndrome (Pre-MetS), and metabolic syndrome (MetS), according to number of metabolic syndrome elements. Results The prevalence of metabolic syndrome was highest in Taeumin (Pre-MetS: 48.2%, MetS: 41.2%). The risk factors for metabolic syndrome are dietary amount, speed of eating, and sleep quality in Taeumin, and dietary amount and sleep quality in Soyangin. Conclusions The life style affecting the metabolic syndrome were different according to the constitution. It is necessary to manage life style considering the Sasang constitution

• 사상체질의학회지
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• 제32권2호
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• pp.10-21
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• 2020

Objectives Genome-wide association studies(GWAS) is a useful method to identify genetic associations for various phenotypes. The purpose of this study was to develop predictive models for Sasang constitution types using genetic factors. Methods The genotypes of the 1,999 subjects was performed using Axiom Precision Medicine Research Array (PMRA) by Life Technologies. All participants were prescribed Sasang Constitution-specific herbal remedies for the treatment, and showed improvement of original symptoms as confirmed by Korean medicine doctor. The genotypes were imputed by using the IMPUTE program. Association analysis was conducted using a logistic regression model to discover Single Nucleotide Polymorphism (SNP), adjusting for age, sex, and BMI. Results & Conclusions We developed models to predict Korean medicine constitution types using identified genectic factors and sex, age, BMI using Random Forest (RF), Support Vector Machine (SVM), and Neural Network (NN). Each maximum Area Under the Curve (AUC) of Teaeum, Soeum, Soyang is 0.894, 0.868, 0.767, respectively. Each AUC of the models increased by 6~17% more than that of models except for genetic factors. By developing the predictive models, we confirmed usefulness of genetic factors related with types. It demonstrates a mechanism for more accurate prediction through genetic factors related with type.

• 사상체질의학회지
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• 제22권1호
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• pp.17-25
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• 2010

1. Objectives: Voice diagnosis has been used to classify individuals into the Sasang constitution in SCM(Sasang Constitution Medicine) and to recognize his/her health condition in TKM(Traditional Korean Medicine). In this paper, we purposed a new speech classification algorithm for Sasang constitution. 2. Methods: This algorithm is based on the SVM(Support Vector Machine) technique, which is a classification method to classify two distinct groups by finding voluntary nonlinear boundary in vector space. It showed high performance in classification with a few numbers of trained data set. We designed for this algorithm using 3 SVM classifiers to classify into 4 groups, which are composed of 3 constitutional groups and additional indecision group. 3. Results: For the optimal performance, we found that 32.2% of the voice data were classified into three constitutional groups and 79.8% out of them were grouped correctly. 4. Conclusions: This new classification method including indecision group appears efficient compared to the standard classification algorithm which classifies only into 3 constitutional groups. We find that more thorough investigation on the voice features is required to improve the classification efficiency into Sasang constitution.

• Genomics & Informatics
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• 제7권2호
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• pp.107-110
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• 2009

In Sasang constitutional medicine, both disease susceptibility and drug response are considered to be related to the characteristics of an individual's physiology and psychology: a theory which is central to traditional Korean medicine. Based on such observable characteristics, Sasang constitutional medicine classifies people into four constitutional types. Genetic studies of Sasang constitution would help reveal the inheritance patterns and models of the typological traits and, moreover, help with traditional medical diagnosis and treatment. To investigate the heritable aspect of Sasang constitution, we collected various pedigrees from South Korea. The study population has 101 pedigrees composed of 593 individuals. The determination of the Sasang constitution type of each individual was performed by doctors who diagnose the Sasang constitutional type of individuals as part of their professional practice. We calculated estimates of familial correlation and heritability. Parent-Offspring pairs showed the strongest familial correlation of Sasang constitutional type, with the correlation values of 0.21 and 0.28, followed by sibling pairs with the value ranging between 0.14 and 0.25. From the heritability analysis conducted with the Variance-Component method, the heritability of TE (Tae-Eum) type, SY (So-Yang) type, and SE (So-Eum) type were 55%, 41%, and 47%, respectively. This pattern of heritability was consistent with different set of analyses, which suggest the robustness of our result. Our result clearly shows that the Sasang constitution type is heritable, and further genetic analysis based on our result will shed light on the biological mechanism of Sasang constitution.

• 동의생리병리학회지
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• 제23권6호
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• pp.1267-1272
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• 2009

The purpose of this study is to survey the importance of items for the physiological and pathological symptoms for estimating a health condition according to Sasang constitution to establish the SHI(Sasangin Health Index) which will reflect the concept of inherent vitality. We surveyed expert opinion with questionnaires from 20 Sasang constitution specialists. The questionnaire was composed of 57 items on physiological and pathological symptoms and specialist opinions. Each item was marked from A to E according to importance in evaluating health state in each constitution, and if the mean score of an item was over 3.0, the item was regarded as important. Important indexes among physiological symptoms were diet, digestion condition, perspiration condition, frequency of defecation, heat and cold response, and temperature of drinking water in Soeumin, pathologic perspiration and defecation condition in Soyangin, repast, perspiration condition, and the amount of drinking water in Taeeumin, and urination frequency in Taeyangin. Important indexes among pathological symptoms were sighing, indigestion, and abdominal pain in Soeumin, oral condition, chest distress, brash, and amnesia in Soyangin, eye condition, palpitation, and edema in Taeeumin, and vomiting and incapacity of the lower limbs in Taeyangin. There are different health evaluating index and priority order in it according to Sasang constitution.

• 사상체질의학회지
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• 제34권4호
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• pp.13-26
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• 2022

Objectives The purpose of this study was to explore the differences in allergic reactions by type of Sasang constitution using multiple allergen simultaneous test(MAST). Methods This study was conducted using the big data of Korean medical health checkups. Subjects with a history of allergic disease, Sasang constitution type information, and MAST results were included. Subjects who had taken drugs before MAST that affected allergic reactions were excluded. We compared total immunoglobulin E(IgE) concentrations, and the number of positive antigens by Sasang constitution using analysis of variance. The presence or absence of a positive reaction and specific IgE concentration classes of 92 antigens in MAST were analyzed by Fisher's exact test or Chi-squared test. Results The distribution of Sasang constitutional types of Tae-Yang, Tae-Eum, So-Yang, and So-Eum among 147 subjects was 2.7%, 42.9%, 38.1%, and 16.3%, respectively. There was no statistically significant difference in the total IgE concentration, the number of positive antigens, and specific IgE concentration classes for each antigen. There was a statistically significant difference in MAST-positive reaction for alder and pine antigens by type of Sasang constitution, and Tae-Eum had the most. Conclusions Tae-Eum showed a relatively strong positive reaction to a large number of antigens compared to the other types, but no statistically significant difference was observed. It is necessary to continuously investigate allergic reactions to provide evidence for the treatment of allergic diseases by Sasang constitution.

• 사상체질의학회지
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• 제36권2호
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• pp.27-38
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• 2024

Objectives The purpose of this study was to compare sleep quality and chronotype by Sasang constitution and examine the relationship with nutritional status. Methods This study used 672 follow-up data from the Korean Medicine Daejeon Citizen Cohort study (KDCC). Demographic, Sasang constitution, sleep quality, chronotype, and nutritional status evaluation were conducted based on questionnaires. Multiple linear regression analysis was used to confirm the relationship between sleep quality and chronotype according to Sasang constitution and nutritional status. Results The relationship between sleep quality and chronotype by Sasang constitution and nutritional status is that Taeeum nutritional index is related to sleep quality (adj. B = -0.46, 95% CI = -0.79 ~ -0.12) and chronotype (adj. B = 0.38, 95% CI = 0.24 ~ 0.52), and Soeum and Soyang showed an association between nutritional indices only in chronotype (adj. B = 0.43, 95% CI = 0.23 ~ 0.63 in SE, adj. B = 0.55, 95% CI = 0.38 to 0.73 in SY). Conclusions This study confirmed the relationship between sleep quality and chronotype and healthy eating habits. For a balanced nutritional status, overall sleep management is necessary. Based on the results of this study, we intend to use it as basic data on the impact of the relationship between nutritional status and chronotype by Sasang constitution on health.

• 정보처리학회논문지B
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• 제15B권1호
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• pp.17-24
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• 2008

본 논문에서는 사상 체질 분류를 음성 분석 정보값의 비교, 분석을 통해 제안하고자 한다. 이를 위해 본 논문에서는 사상체질의 객관적 지표를 마련하기 위한 전체 시스템 구성 중 1차 단계로써 피부 진단을 통한 소음인의 분류 과정과 연계하여 음성 신호 분석에서 발생하는 정보의 출력값에 의해 태음인을 분류하는 방법을 제안하고자 한다. 우선 각 사상 체질별로 뚜렷한 특징을 보유하고 있는 집단군을 구성하고 이들의 음성 특성을 분류하여 음성학적 요소를 추출하고자 한다. 또한 출력된 결과값을 토대로 체질 집단별 차이점과 유사점을 통하여 태음인을 분류하고자 한다. 끝으로 실험에 의해 제안한 방법의 유용성을 입증하고자 한다.

• 한국간호교육학회지
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• 제10권1호
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• pp.84-93
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• 2004

Purpose: This study was conducted to investigate the subjective degree of fatigue, the degree of fatigue depending on constitution, and the factors related to fatigue in middle-aged women. Method: Data were collected from 51 patients, registered at Oriental Medicine Hospital in J-city and K-city respectively. The instrument used in this study were the Multidimensional Assessment of Fatigue and the Questionnaire of Sasang Constitution Classification Ⅱ. Data analysis was done SPSS Result: The characteristics of constitution in middle-aged women could be divided into three: twenty six people of Soeumin, thirteen people of Taeumin, and twelve people of Soyangin. The degree of fatigue in middle-aged women: the average score 30.61 out of the total score 40. Subdivision of fatigue scores: common fatigue degree 7.71, distress due to fatigue 7.67, degree of daily activity fatigue 7.43, and fatigue frequency in the previous week 7.84. There were significant differences in the degree of fatigue depending on constitution in middle-aged women(p=.033). This study revealed weight, exercise, and drinking are important factors that can exert influence on the degree of fatigue. Also, there was a big difference in the degree of fatigue depending on constitution. Conclusion: In conclusion, fatigue is one of the difficult problems with middle-aged women. And this study revealed that change in the weight(especially loss of weight), physical exercise, and drinking are important factors that can exert influence on the degree of fatigue. Also, there was a big difference in the degree of fatigue depending on constitution. Therefore it is necessary to develop Korean nursing intervention to providing an appropriate environment where there is the harmony of the dual principles of the negative and positive, and patients can be taken care of properly.

• 대순사상논총
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• 제40집
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• pp.77-114
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• 2022

이 연구의 목적은 대한민국헌법에 구현된 법체계의 기본원리를 기준으로 『도헌』의 사상적 배경과 법률적 구성, 그리고 제도적 장치의 권력분립에 대해 분석하는 것이다. 『도헌』의 사상적 배경은 대순진리이다. 대순진리에는 선천의 상극적인 신의 의지로 인해 상극적인 자연법, 상극적인 자연 상태, 상극적인 인간으로 이루어진 진멸할 위기의 세상을 상제가 상생의 자연법, 상생의 자연 상태, 상생의 인간으로 개벽하는 우주 자연의 질서에 대한 패러다임의 전환이 설명되어 있다. 패러다임의 전환 시기 상제는 인간에게 상생적 인간이 되도록 신의 의지를 밝혔다. 따라서 『도헌』은 인간에게 부여된 상제의 의지를 도인의 사명으로 받아들여 실행하기 위한 '도인의 권리와 의무'에 기초한 근본규범이다. 『도헌』의 법률적 구성은 본문, 부록으로 되어 있고, 본문은 총칙, 도인의 권리와 의무, 연원, 제도적 장치로 구성되어 있다. 제도적 장치에는 중앙본부의 체계, 중앙종의회, 포정원, 정원, 종무원, 사업, 재정, 감사원, 도헌 개정 등으로 구성되어 있다. 『도헌』의 법률적 구성은 헌법의 법률 구성과 유사하다. 차이점은 헌법이 '최대권리 최소의 무의 원칙'이 적용된 데 반해 『도헌』에는 도인의 사명 완수를 위해 권리보다 의무가 더 많이 규정되어 있다. 『도헌』의 제도적 장치에는 권력분립의 원리가 적용되어 있다. 『도헌』상 중앙본부의 조직 형태는 도전의 별세 이전과 이후로 나누어서 살펴보았다. 도전의 별세 이전 중앙본부의 조직 형태는 입헌군주제와 유사하다. 『도헌』 상 도전의 별세 이후 중앙본부의 조직 형태는 의원내각제와 유사하다. 그리고 중앙본부의 기능 간 권력분립은 입법권(중앙종의회), 행정권(종무원), 사법권(감사원) 등 삼권분립의 원리이다. 중앙정부의 기능 내 권력분립은 첫째, 중앙종의회와 종무원 간에는 입법부 우위형(의회정부제), 둘째, 중앙종의회와 감사원 간에는 입법부 우위형(의회정부제), 셋째, 종무원과 감사원 간에는 사법부 우위형이다. 그리고 중앙본부와 방면 조직 간에는 수직적 권력분립의 원리가 작용하고 있다.