• Title/Summary/Keyword: Constituent

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Effect of Moutan Cortex Radicis on Gene Expression Profile of Differentiated PC12 Rat Cells Oxidative-stressed with Hydrogen Peroxide (모단피의 PC12 cell 항산화 효과와 관련 HO, MIF, COMT 유전자 발현에 미치는 영향)

  • Son Mu Song;Rho Sam Woong;Ko Eun Jung;Na Youn Gin;Bae Hyun Su;Hong Moo Chang;Shin Min Kyu
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.17 no.4
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    • pp.905-913
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    • 2003
  • Oriental medicine explains aging as the weakening of Kidney-ai, and Kidney-strengthening herbal medicines such as Yukmijihwang-tang have been studied for anti-aging effects. In Western Medicine, the hypothesis that reactive oxidant species(ROS) contribute to the aging process is generally accepted. It has been reported that Moutan Cortex Radicis extract (MCR) was the most effective constituent of Yukmijihwang-tang in decreasing ROS production in oxidative-stressed cells. The purpose of this study is to confirm the anti-oxidant effect of MCR on PC12 cells, the expression of Heme oxygenase (HO), Macrophage migradon inhibitory factor (MIF), Catechol-O-methyltransferase (COMT) using real time RT PCR. PC12 cells were treated without or with hydrogen peroxide in the presence or absence of MCR using MTS assay. Hydrogen peroxide decreased the viability of PC12 cells by 53% and MCR did not influence that of stressed PC 12 cells irrespective of dose or incubation period. However, MCR showed an inhibitory effect on production of ROS in stressed cells, both dose and incubation time dependently. In particular, 1 ㎎/㎖ of MCR for 24 h culture almost returned to normal level. In the quantiation of anti-aging related gene expression, MCR at 1 ㎎/㎖ increased the expression of HO by 370%, MIF by 180% and COMT by 280% through real time RT PCR. In conclusion, MCR treatment protected PC12 cells from hydrogen peroxide and decreased ROS production and enhanced anti-oxidative gene expression such as HO, COMT and MIF, which suggests that MCR is involved in controlling anti-aging of nerve cells through elimination of cytotoxic stimuli.

An Analysis on Behavior Characteristics between Gifted Students and Talented Students in Open-end Mathematical Problem Solving (개방형 문제 해결과정에서 수학 영재아와 수학 우수아의 행동특성 분석)

  • Shin In-Sun;Kim See-Myung
    • Communications of Mathematical Education
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    • v.20 no.1 s.25
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    • pp.33-59
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    • 2006
  • This study is intended to reconsider the meaning of the education for gifted/talented children, the foundation object of science high school by examining the behavior characteristics between gifted students and talented students in open-end mathematical problem solving and to provide the basis for realization of 'meaningful teaming' tailored to the learner's level, the essential of school education. For the study, 8 students (4 gifted students and 4 talented students) were selected out of the 1 st grade students in science high school through the distinction procedure of 3 steps and the behavior characteristics between these two groups were analyzed according to the basis established through the literature survey. As the results of this study, the following were founded. (1) It must be recognized that the constituent members of science high school were not the same excellent group and divided into the two groups, gifted students who showed excellence in overall field of mathematical behavior characteristics and talented students who had excellence in learning ability of mathematics. (2) The behavior characteristics between gifted students and talented students, members of science high school is understood and a curriculum of science high school must include a lesson for improving the creativity as the educational institutions for gifted/talented students, unlike general high school. Based on these results, it is necessary to try to find a support plan that it reduces the case which gifted students are generalized with common talented students by the same curriculum and induces the meaningful loaming to learners, the essential of school education.

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Comparison of the Nutrient Composition and Quality of the Root of Allium hookeri Grown in Korea and Myanmar (국내 및 미얀마에서 재배된 삼채뿌리의 영양성분 및 품질특성 비교)

  • Park, Joo-Young;Yoon, Kyung-Young
    • Korean Journal of Food Science and Technology
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    • v.46 no.5
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    • pp.544-548
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    • 2014
  • This study was conducted to investigate the nutritional components and quality characteristics of the root of Allium hookeri grown in Korea and Myanmar. The root of A. hookeri grown in Hadong, Korea (KR), contained higher levels of carbohydrate, crude ash, and crude lipid, but the root of A. hookeri grown in Shan, Myanmar (MR), contained higher levels of crude protein and crude fiber. The free sugar and organic acid contents were higher in KR than in MR. Fructose, glucose, and sucrose were the major free sugars and arginine was the major free amino acid. KR contained higher amounts of essential amino acids, non-essential amino acids, ${\gamma}$-amino butyric acid, and citrulline than MR. Potassium was a prominent mineral constituent in both KR and MR, and KR contained higher mineral content than MR. KR contained twice the amount of sulfur and crude saponin, relative to MR.

Changes of Fatty Acid Composition in Shank During Heating Time and Frozen Storage (사태의 가열시간 및 냉동저장에 따른 지방산 조성 변화)

  • Kim, Kyung-Ae
    • Korean journal of food and cookery science
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    • v.2 no.2
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    • pp.8-15
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    • 1986
  • This study was carried out to investigate changes of the lipid contents and the fatty acid composition in shank during heating time and frozen storage. 1. The total lipid contents of raw shank were about 3.57% and decreased stepwise during heating time 30, 60, 90 min and frozen storage(24hrs) The contents of neutral lipid, glycolipid and phospholipid were 70.71%, 6.36%, and 22.93% in raw shank, and neutral lipid contents were decreased, whereas Phospholipid contents were increased according to heating tide. In frozen storage, neutral lipid and glycolipid contents were increased, while phospholipid contents were decreased. 2. Lipids of shank possessed about 8 kinds of fatty acid as the constituent by gas-liquid chromatography analysis. The main fatty acids were oleic acid, palmitic acistearic acid and linoleic acid: the fatty acids of total lipids in raw shank were 43.48% of oleic acid, 23.13% of palmitic acid,12.00% of stearic acid and 6.75% of linoleic acid. Also the fatty acids were 43.32% of oleic acid, 23.26% of palmitic acid, 9.30% of stearic acid 2.15% of linoleic acid in neutral lipid, 22.63% of oleic acid, 8.44% of palmitic acid, 11.98% of stearic acid, 27.01% of linoleic acidin glycolipid, 39.38% of oleic acid, 15.89% of palmitic acid, 15.55% of stearic acid, 17.49% of linoleic acid in phospholipid. 3. The fatty acid pattern of total lipid, neutral lipid, glycolipid and phospholipid was not any changes, whereas there was a difference in the fatty acid contents: palmitic acid and stearic acid of total lipid were decreased in the 30 min and 60 min heating but increased in 90min heating, and linoleic acid of neutral lipid was increased stepwise during heating time and frozen storage. Also palmiict acid of glycolipid was increased gradually and linoleic acid in heating time 30, 60 min was higher than 90 min and frozen storage. Among fatty acids in phoapholipid, oleic acid was increased during heating time, while decreased in frozen storage, and linoleic acid was not any change but linolanic acid was increased. UFA/SFA of phospholipid was the highest when heating time was 60 min. From above results, it was found that when heating time was 60 min beneficial nutritionally, comparing with changes of fatty acid composition according to the heating time aid frozen storage.

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Changes of Off-Odor Constituent and Parishin Derivatives of Fermentation of Gastrodia elata Rhizome by Lactic Acid Bacteria Strains (천마의 젖산발효에 따른 이취성분 및 Parishin 유도체의 변화)

  • Song, Young Eun;Lee, In Sok;Song, Eun Ju;Choi, Min Kyung;Han, Hyun Ah;Shin, So Hee;Choi, So Ra;Lee, Ki Kwon;Kim, Myung Kon;Park, Shin Young
    • The Korean Journal of Food And Nutrition
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    • v.30 no.5
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    • pp.973-982
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    • 2017
  • Gastrodia elata Blume often has been used for the treatment of headaches, convulsions, hypertension, and neurodegenerative diseases. The main active constituents are gastrodin, 4-hydroxybenzyl alcohol, vanillyl alcohol, 4-hydroxybenzylaldehyde and parishin A, B, C and E. Because Gastrodia elata has also unacceptable off-odor (swine barnyard-like) for food, there is a need to reduce it as well as allow for greater utilization as a functional food materials. In this study, a major off-odor producing substance of Gastrodia elata was fractionated by steam distillation and silica gel column chromatography. The substance was identified as p-cresol(4-methyl phenol) by GC-MS analysis and comparison of the retention time with that of an authentic compound in GC. The content of p-cresol in fermented Gastrodia elata was decreased. A fermented sample of Latobacillus sakei for 2 days was reduced to 54.7%, when compared with a unfermented sample. The five parishin derivatives in Gastrodia elata were identified by HPLC-MS analyses, and a comparison of HPLC retention times with those of authentic compounds. When compared with parishin derivatives of an unfermented Gastrodia elata, those of Gastrodia elata fermented by L. sakei, increased to 18.3% for 2 days. Increases of about 14.0~38.4% of the total phenolic compounds and 57.4~77.3% total flavonoids were found in fermented extracts, by 3 lactic acid bacteria strains. They were compared with $97.1{\pm}2.9{\mu}g/g$ and $40.9{\pm}2.0{\mu}g/g$ in the unfermented control, respectively. The extracts of Gastrodia elata Blume that were fermented by lactic acid bacteria had higher DPPH free radical scavenging activity and FRAP reducing power than the unfermented control.

The study on the quality characteristics factor of medium-sized orbit scroll (중형 선회 스크롤의 품질 특성 인자에 대한 연구)

  • Kim, Jae-Gi;Lim, Jeng-Taek;Kang, Soon-Kook;Park, Jong-Soon
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.17 no.9
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    • pp.718-723
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    • 2016
  • The use of the scroll compressor in the air conditioning of medium-sized vehicles has increased because of its low torque fluctuation, high energy efficiency and low noise. In addition, the main components of the compressor have been changed from steel to aluminum to reduce its weight, following studies on the constituent materials. The processing precision of the fixed scroll and orbiting involute scroll wrap of the scroll compressor must be below $10{\mu}m$. To ensure this, the surface roughness and contour tolerance are measured. To improve the hardness of the orbiting scrolls using aluminum subjected to anodizing treatment and as the base material, we used a sealing treatment and measured the resulting characteristics. The aluminum materials were made of an Al-Mg-Cu based alloy including small amounts of Ni, Fe, and Zn. The surface roughness was less than $3{\mu}m$ and the processing accuracy was within $10{\mu}m$. Also, the hardness of the nanodiamonds with CNTs used in the sealing treatment was more than 450. This was found to improve the hardness of the material by 50% or more compared to the water sealing treatment and there was little difference between the use of carbon nanotubes and nanodiamonds as sealing materials.

Development of component architecture to support IoT management (IoT 및 네트워크 관리 지원을 위한 컴포넌트 아키텍처 개발)

  • Seo, Hee Kyoung
    • Smart Media Journal
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    • v.6 no.2
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    • pp.42-49
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    • 2017
  • It is important to realize automation services by communicating in IoT with humans, objects & objects, and forming a common network. People used web like the most powerful network way to sharing things and communication. Therefore the efficiency method communication between each device and the web in IoT could be different from ones. The best method for high quality software product in web applications is software reuse ; Modules, classes, patterns, frameworks, and business components are reusable elements of various perspectives. Components is plugged with others through well-defined interfaces, which can overcome the operation and complexity of application development. A web-based distributed environment for IoT applications is a standard architecture use information collected from various devices for developing and using applications. For that reason, the network management which manages the constituent resources for the best service control in IoT application is required as a sub-layer support service in most applications as well as individual applications. In this paper, we measure to develop a network management system based not only by components but on heterogeneous internetworks. For procedure this, we clarify a component architecture for classifying and classify also the component needed in the IOT and network domain or order the type of real network management system.

A Study on the Ellipsis of Case markers through the Hangul letters of Hyun-Poong Kwak's family (현풍(玄風) 곽씨(郭氏) 언간(諺簡)의 격조사(格助詞) 생략(省略)에 대한 고찰(考察))

  • Jeon, Byeong-Yong
    • (The)Study of the Eastern Classic
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    • no.33
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    • pp.413-435
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    • 2008
  • This study is purposed to analyze the appearances and functions of ellipsis of case markers through the Hangul letters of Hyun-Poong Kwak's family in the early 17th century. Hangul letters appear more colloquial than typography, and ellipsis is the one of main features of it. Generally, 'ellipsis' occurs when a constituent of a sentence deliberately leaves out of a sentence, because it is repeated or can be deduced by the context or occasion. As Hangul letter is written for a specific person, 'ellipsis' occurs more often than typography written for unspecified individuals. The ellipsis of case markers are not an exception. The ellipsis has functions as follow. The first, function is 'brevity.' Communication can be more convenient by ellipsis. Next will be 'informality.' Informality caused by ellipsis can make people express their thoughts and feelings fluently and naturally. It is the reason that spoken language has more frequently occurred ellipses than written language. The third function is 'quickness.' The same information can be delivered more quickly by the sentence using ellipsis than not using. In the 21st Century, ellipsis is misused in netizen communication owing to the quickness. The last function should be 'the effect of a literary style.' The effects can embody through ellipsis such as 'rhythm effect', 'letter style effect', 'translation style effect.' As a result of analyzing ellipsis of case markers, frequency follows the order below.[subjective objective > Locative > Dative > Commutative > Instrumental]

Aristotle and Praxis (아리스토텔레스와 실천행위)

  • Jeon, Jae-won
    • Journal of Korean Philosophical Society
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    • v.116
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    • pp.371-387
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    • 2010
  • On the one hand Aristotle seems to insist that practical acts are intrinsically good. On the other hand his doctrine of certain connected concepts is such that as a consequence practical acts must be considered good due to their being means to eudaimonia. This Aristotelian dilemma challenged by commenters. Cooper bases his attack on a consideration of Aristotle's account of deliberations. Deliberation is not just concerned with means in a strictly causal sense, but with things that contribute to the end. And these may also be constituent parts of complex ends or particular things that a given end may be seen to consist in. The difference between energeia and kinesis implies the distinction between praxis and poiesis. In kinesis such as 'building a house' and 'trying to save a child from drowning' we cannot sever, logically, 'the act' from the intended act-result, since no act will be left once that logical operation has been performed. The definition of poiesis relies on the possibility of such severance. But the fact that an act is kinesis has no implications whatever for the question whether it is a praxis or poiesis.

A Study on the Judgment Criteria for the Trademark Dilution of Famous Marks

  • Park, Jong-Ryeol;Noe, Sang-Ouk
    • Journal of the Korea Society of Computer and Information
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    • v.24 no.10
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    • pp.225-232
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    • 2019
  • The trademark dilution of famous marks as a kind of unfair competition practice is defined and regulated in Article 2 (1) (c) of the Unfair Competition Prevention and Trade Secret Protection Act (hereinafter referred to as the Unfair Competition Prevention Act), which was newly established according to the amendment of the Act on February 3, 2001. Famous trademarks are universally protected in all around the world, which are likewise protected in the Republic of Korea by the Unfair Competition Prevention Actin line with such international trends. In order to establish the trademark dilution of famous marks, it is necessary to have the following characteristics: (1) high reputation of the original mark, (2) use of identical or similar markscompared to the original mark, (3) occurrence of blurring of discrimination or tarnishment of reputation; in particular, with respect to the degree of proof of 'blurring of discrimination or tarnishment of reputation', which is a constituent requirement of the trademark dilution of famous marks, it is reasonable to interpret the trademark dilution as concrete endangerment offense, neither harm-based offense nor abstract endangerment offense, and thus it should be considered that the crime is established if a specific realistic risk of blurring of discrimination or tarnishment of reputation occurs. Furthermore, in relation to the specific criteria of 'blurring of discrimination or tarnishment of reputation', it is necessary to comprehensively judge the degree of individual behavior in specific matters as a normative factor as well as the psychosocial viewpoint of the general public.