• Microbiology and Biotechnology Letters
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• v.27 no.1
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• pp.54-61
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• 1999

Measurement of inhibition of bioluminescence in Photobacterium phosphoreum has been porposed as a sensitive and rapid procedure to monitor toxic substances. However, at first, $EC_{50}$ which shows degree of toxicity to each toxic substances must be calculated. QSAR (Quantitative Structure Activity Relationship) model can be used to estimate $EC_{50}$ to save time and endeavor. Moderately high correlation coefficients ($r^2{\geq}$ 0.97) were calculated from the linear correlation between $EC_{50}$ and molecular connectivity indices of CAHs (chlorinated aliphatic hydrocarbons)such as $^0X$, $^0X^V$, $^1X$, $^2X$ and $^3X^v_c$ and quadratic correlation between $EC_{50}$ and $^0X$, $^0X^V$, $^2X^V$, $^3X_c$, $^3X^V_c$ and P. It shows that the molecular connection indices in carbon structure is contributed to biological characters with linear relation and that in the other one with quadratic relation. The $EC_{50}$ of chlorophenol derivatives had quadratic relation with the value of octanol/water prtition coefficients ($r^2$=0.99) and linear and quadratic relation with the number of chlorine compound (($r^2{\geq}$0.94). This confirms the already known trend of increasing toxicity with increasing ability of a compound to diffuse through cell membrane and number of chlorine substitution.

• Korean Institute of Interior Design Journal
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• v.27 no.3
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• pp.14-23
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• 2018

The spatial planning of the elderly care facility plans is analyzed using space syntax in terms of encouraging the social interaction of the residents in this study. First, through the visibility graph analysis, openness and accessibility of space is analysed. Second, the walking behavior of residents through agent analysis model is simulated. Third, the space planning methods for the elderly care facilities are proposed based on the results. The results are as follows. According to the visibility graph analysis, the main corridor has high visual openness and high accessibility. The visual openness and accessibility of the unit living room, where social interaction among residents is possible in each unit, is low. Space planning is needed to increase direct protection and observation of employees to the unit living room. The location of the nurse station that manages the entire floor needs to be located where the openness and accessibility is most high. The nursing station should have a high degree of connectivity to the entire space, so that any accidents can be managed and contact is accessible. Through the agent simulation the flow from the center to each unit space is highest in the corridor space and the inflow to the private rooms and the living room are similar. Therefore, it is necessary to plan the accessibility of the unit living room more for the natural inflow of residents.

• Journal of the Korean Institute of Gas
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• v.22 no.2
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• pp.1-20
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• 2018

Despite many measures, still from time to time catastrophic events occur, even after reviewing potential scenarios with HAZID tools. Therefore, it is evident that in order to prevent such events, answering the question: "What can go wrong?" requires more enhanced HAZID tools. Recently, new system based approaches have been proposed, such as STPA (system-theoretic process analysis) and Blended Hazid, but for the time being for several reasons their availability for general use is very limited. However, by making use of available advanced software and technology, traditional HAZID tools can still be improved in degree of completeness of identifying possible hazards and in work time efficiency. The new HAZID methodology proposed here, the Data-based semi-Automatic HAZard IDentification (DAHAZID), seeks to identify possible scenarios with a semi-automated system approach. Based on the two traditional HAZID tools, Hazard Operability (HAZOP) Study and Failure Modes, Effects, and Criticality Analysis (FMECA), the new method will minimize the limitations of each method. This will occur by means of a thorough systematic preparation before the tools are applied. Rather than depending on reading drawings to obtain connectivity information of process system equipment elements, this research is generating and presenting in prepopulated work sheets linked components together with all required information and space to note HAZID results. Next, this method can be integrated with proper guidelines regarding process safer design and hazard analysis. To examine its usefulness, the method will be applied to a case study.

• Journal of KIISE:Software and Applications
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• v.26 no.9
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• pp.1095-1104
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• 1999

객체지향 시스템의 개발은 클래스를 통해서 이루어진다. 즉, 문제 영역에 존재하는 중요한 대상 또는 개념을 클래스로 모델링하고, 이로부터 생성된 객체들 사이의 메시지 교환을 통해서 시스템은 구축된다. 또한, 클래스는 정보 은닉을 제공함으로써, 객체지향 시스템의 재사용성과 유지보수성에 상당한 기여를 한다. 그러나, 설계 단계에서 실세계의 대상을 부적절하게 모델링하거나, 또는 유지보수 단계에서 클래스에 무분별한 변경을 가하는 경우 클래스의 품질은 악화될 수 있고, 이는 결국 시스템을 유지보수 하거나 확장하는데 상당한 장애를 초래한다.응집도는 모듈의 구성 요소들 사이의 연관성 정도를 나타내는 척도로서 전통적으로 모듈의 품질을 평가하기 위한 기준으로 사용되어 왔다. 이 논문에서는 클래스의 품질을 평가하는 방법으로서의 클래스 응집도를 제안한다. 즉, 클래스가 실세계의 대상을 적절하게 모델링한다면, 그 구성요소들 사이에 밀접한 관련이 있고 결국 높은 응집도를 가지게 될 것이다. 반대로 실세계의 대상에 대한 적절한 모델이 아니라면, 그 클래스의 구성 요소들 사이에는 밀접한 관련성이 없을 것이고 따라서 낮은 응집도를 보일 것이다.Abstract Object-oriented systems are developed by means of classes; that is, classes captures the essential entities or concepts in the problem domain, and the system is embodied by the interactions of objects instantiated from the classes. In addition to the basic units of object-oriented systems, classes serves as the units of encapsulation, which considerably promote the modifiability and the extensibility of them. However, improper modeling in the design phase or uncontrolled changes during the maintenance phase can degrade the quality of classes, which leads to systems cumbersome to maintain and extend.Cohesion refers to the degree of connectivity among the elements of a single module, and is being used as a factor which characterizes the quality of a module. In this paper, we propose a new cohesion metric for assessing the quality of classes. If a class captures properly the essential features of objects, the members of the class surely have strong relationship among them. On the contrary, the poor relationship among class members can indicate that the class is not a proper model of objects.

• The Transactions of the Korea Information Processing Society
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• v.4 no.5
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• pp.1231-1242
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• 1997

This paper deals with an IP mukticast protocol in support of host mobility. Most of the previous multicast schemes have utilized an underlying logical strucuture of network topology,in order to provide a certain degree of order and predictability.On the other hand,mobility implies that a host location relaative to the rest of the net-work changes with time;the physical connectivity of the entire network is thus modified as move.In this case.some multicast datagrams nay not delivered properly,or may delivered twice or more,to a mobile host because the destinations will keep moving whlist datagrams are dekivered with different time delay.This paper first describes the relation between host mobility and multicast, by exploring the possible interactions,and presents a multicast scheme in support of Internet host mobility.A revised scheme is then proposed to adapt the multicast semantic and to optimize the communication overhead.

• The KIPS Transactions:PartA
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• v.9A no.3
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• pp.333-340
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• 2002

Embedding is a mapping an interconnection network G to another interconnection network H. If a network G can be embedded to another network H, algorithms developed on G can be simulated on H. In this paper, we first propose a method to embed between Hierarchical Cubic Network HCN(n, n) and Hierarchical Folded-hypercube Network HFN(n, n). HCN(n, n) and HFN(n, n) are graph topologies having desirable properties of hypercube while improving the network cost, defined as degree${\times}$diameter, of Hypercube. We prove that HCN(n, n) can be embedded into HFN(n, n) with dilation 3 and congestion 2, and the average dilation is less than 2. HFN(n, n) can be embedded into HCN(n, n) with dilation 0 (n), but the average dilation is less than 2. Finally, we analyze the fault tolerance of HCN(n, n) and prove that HCN(n, n) is maximally fault tolerant.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.21 no.10
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• pp.471-479
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• 2020

In this paper, we analyze features of radical innovative businesses using their patents. Although patents have been used to evaluate outcomes of businesses from the 1980s, it is challenging to use patents for radical innovations. We examined the possibility of taking advantage of patents for an indicator that represents a radical innovation in pharmaceutical industry. To this end, we collected FDA approval data from the U.S. Food and Drug Administration and patent data of 18 pharmaceutical companies. For analysis, we utilized the network centrality analysis and Wilcoxon signed ranked test, which is a non-parametric statistical hypothesis test used to compare two related samples. We observed that a radical innovative company typically cooperates with other research groups, such as universities and companies, and acts as a hub for connectivity in pharmaceuticals. Also, we found that there are differences in centrality between radical firms and non-radical firms. Thus, we expect that the results of this study will help in developing strategies for research and development of pharmaceutical companies and identifying factors affecting radical innovation in the future.

• Journal of the Korean Society of Environmental Restoration Technology
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• v.12 no.6
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• pp.131-142
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• 2009

The purpose of this study is to detect the protection area around the Geum-buk and Geum-nam Mountains for making a sustainable ecological network. The protection area in the Geum-buk and Geum-nam Mountains was analyzed by using spatial data and a field survey for landscape conservation purposes. A survey scope was fixed using digital elevation model, and the protection area was finally determined based on the parcel map called as the Korea Land Information System (KLIS). Here we have several conclusions in this study. First, spatial data used in this study were a map of ecological and natural degree (MEND), forest distribution map, elevation map, slope map, and several maps for the protection area assigned by laws regarding to the natural resources. Second, we used 4 alternatives to determine the best choice for showing the ecological network in the study area. One alternative (alt. 3) of 4 ones was finally chosen as the best condition for making the ecological network. The condition in elevation and slope was a little modified to a lower level in alt, 3. The result derived from alt, 3 reflected the continuity and connectivity in the ecological network and we estimate that the protection area can protect the core area using the buffer zone around the ecological network. Finally the parcel-based protection area in the Geum-buk and Geum-nam Mountains had $493.92km^2$ of the core area, and $233.99km^2$ of the buffer zone, which means the parcel-based protection area increased by $97.76km^2$ in the core area, but decreased by $76.61km^2$ as of in the topographical map.

• The Journal of the Korea Contents Association
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• v.12 no.11
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• pp.303-312
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• 2012

In this paper we investigate the factors influencing the intention to use of smart-phone mobile banking service in China. We include the characteristics of smart-phone, mobile banking service, and users to the research model and also consider user satisfaction as an intervening variable. We try to find and prove the factors influencing the intention to use of smart-phone mobile banking service by surveying 206 chinese users and using structural equation model. This empirical paper proves that mobility, instance connectivity, use convenience, and intimacy give positive effects to intention to use of smart-phone mobile banking service. In addition, this paper indicates some managerial implications that mobility, access speed and the easy user interface can help to increase the degree of user acceptance.

• Korean Journal of Remote Sensing
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• v.6 no.2
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• pp.89-113
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• 1990

The purpose of this study is to develop means to apply GIS and remote sensing technology to the analysis of Korean urban open spaces. To achieve this objective, a framework of analysis of urban open spaces was developed, and then the framework was applied for the evaluation of the potential and suitability of open spaces of Ansan City, which is a new town developed to accomodate industries relocation from Seoul, Korea, mainly due to their pollution problems. The software used in this study are IDRISI, a grid-based GIS, and KMIPS, a remote sensing analysis system. Both packages are based on IBM PC/AT computers with Microsoft DOS. Landsat MSS and TM data were used for the land use classification, land use change detection, and analysis of transformed vegetation indices. The size of the geographic data base is 110 rows and 150 columns with the spatial resolution of 100m$\times$100m. The framework of analysis includes both quanititative and qualitative analysis of open spaces. The quantitative analysis includes size and distribution of open spaces, urban develpment of open spaces, and the degree of vegree of vegetation removal of the study area. The qualitative analysis includes evaluative criteria for primary productivity of land, park use potential, major visual resources, and urban environmental control. The findings of this study can be summarized as follows. First, the size of builtup areas increased 18.73km$^2$, while the size of forest land decreased 10.86km$^2$ during last ten years. Agricultural lands maintained its size, but shifted toward outside of the city into forest. Second, the potential of open spaces for park use is limited mainly due to their lack of accessibility and connectivity among open spaces, in spite of ample acreage and good site conditions. Third, major landscape elements and historic sites should be connected to the open space system of the city by new accesses and buffers.