• Clinical and Experimental Pediatrics
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• 제54권12호
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• pp.512-514
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• 2011

Congenital syphilis is one of the most well-known congenital infections, yet it remains a worldwide public health problem. Congenital syphilis can involve any organ system and present with various symptoms. However, early diagnosis of congenital syphilis is difficult because more than half of the affected infants are asymptomatic, and the signs in symptomatic infants may be subtle and nonspecific. Here, we report a case of congenital syphilis with only a skin rash, which led to a delay in diagnosis. This case indicates that congenital syphilis should be considered throughout early childhood.

• Pediatric Infection and Vaccine
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• 제29권3호
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• pp.161-165
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• 2022

We report a case of successful treatment of congenital syphilis in an extremely preterm baby. A 1,395 g female infant was born by emergency Caesarean section due to preterm labor and breech presentation at gestational age at 29 weeks and 3 days with an Apgar score of 2 and 4 at 1 minute and 5 minutes, respectively. The mother of the newborn, an illegal immigrant who did not receive any antenatal care, was diagnosed as active syphilis infection by reactive rapid plasma regain (RPR) (titer 1:128) just before the delivery. Upon birth, the newborn presented with various clinical manifestations, including severe respiratory distress syndrome, persistent pulmonary hypertension of the newborn, disseminated intravascular coagulopathy, desquamation and scaling of the whole body, and osteolytic changes of long bone ends. Results of laboratory tests showed signs of early congenital syphilis, including positive syphilis reagin test (12.7 R.U.), reactive with RPR titer of 1:64, and positive for immunoglobulin (Ig) M and IgG fluorescent treponemal antibody absorption test. However, after completion of penicillin G treatment for two weeks, laboratory results dramatically improved, showing a negative syphilis reagin test (0.5 R.U.) and non-reactive in RPR. In conclusion, the incidence of congenital syphilis is prone to be resurgent in South Korea, neonatologists should be fully aware of the clinical features of congenital syphilis because early diagnosis and prompt treatment are essential in order to reduce the social and economic burden due to congenital syphilis.

• Journal of Yeungnam Medical Science
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• 제24권2호
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• pp.333-338
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• 2007

A preterm newborn affected by congenital syphilis, born to mother not treated during pregnancy is described. The clinical picture was characterized by respiratory distress, cutaneous manifestations, massive hepatosplenomegaly, severe anemia, thrombocytopenia, disseminated intravascular coagulation syndrome and hypoalbuminemia. The patient was treated with daily injections of 190,500 units of crystalline penicillin G for 14 days. Premature infants with these symptoms and signs should be evaluated for congenital syphilis.

• Neonatal Medicine
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• 제15권2호
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• pp.207-211
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• 2008

저자들은 산전 진찰을 받지않아 매독에 감염되었는지 모르고 지내던 산모에서 태어나, 빈혈, 혈소판 감소증, 자반, 간비종대와 다량의 늑막삼출과 복수가 동반된 미숙아에서 선천성 매독에 의한 비면역성 태아수종으로 진단하여 적절한 치료 후 생존된 1례를 경험하였기에 보고하는 바이다.

• Clinical and Experimental Pediatrics
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• 제52권6호
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• pp.710-712
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• 2009

선천성 매독은 매우 드문 질환이기는 하나 심각한 질환을 유발할 수 있어 모자보건의 주요부분을 차지하고 있다. 4개월 남아가 좌측 팔의 운동장애로 내원하여 시행한 방사선 사진에서 상완골 골절이 발견되었으며 아동학대가 의심되어 시행한 추가 검사에서 선천성 매독으로 진단되었고 환아와 환아 부모에 대한 치료가 이루어졌다. 저자들은 이 환아의 진단과 치료과정에 대해 보고하면서 임산부와 신생아에 대한 매독선별검사의 중요성에 대해 강조하는 바이다.

• Pediatric Infection and Vaccine
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• 제21권1호
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• pp.65-70
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• 2014

선천성 매독은 산전진찰로 예방할 수 있음에도 불구하고, 여전히 문제가 되고 있다. 최근에는 선천성 매독과 관련된 혈뇨나 폐렴이 보고된 증례가 없었으나 저자들은 적절한 산전치료를 받지 못한 산모에게서 태어난 22일된 남아에게서 발생한 선천성 매독에 동반된 신증후군과 폐렴의 증례를 보고한다. 선천 매독의 진단은 혈청학적 검사로 확진하였고, 환아는 페니실린 G 치료를 받고 회복되었다. 신생아에게서 임상증상은 매우 불확실할 수 있어, 질환에 대한 인식이 지연 될 수 있다. 따라서 선천성 매독의 예방에는 철저한 산전관리가 필수적이다. 만약 산모가 적절한 산전진찰을 받지 않았을 경우에는 신속한 혈청학적 진단이 반드시 시행되어야 할 것이다.

• Journal of Oral Medicine and Pain
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• 제7권1호
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• pp.41-46
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• 1982

The patient, 11 yeats old male was examined for routine oral health care. He had been hospitalized for treatment of nephritis. Hos physical condition os mental retarded & undergrowth state. In oral examination, notch on cutting edge and screw-driver shaped crown of maxillary central incisors, narrow crown and dwarfed & pinched occlusal surface of lower first molars and scars(rhagades) on the angle of the lip were shown. We diagnosed the above symptoms as dental defects of congenital syphilis; Huchinson's inscisors and mulberry molar.

• 대한간호
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• 제6권6호통권32호
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• pp.55-59
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• 1967

• 대한치과의사협회지
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• 제22권6호통권181호
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• pp.465-465
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• 1984

• 대한소아치과학회지
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• 제11권1호
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• pp.255-259
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• 1984

Ectodermal dysplasia is a rare hereditary abnormality of which the outstanding characteristics are hypodontia, hypohidrosis and hypotricosis. Patient afflicted with this malformation shows a typical face resembling that of congenital-syphilis. Dental abnormality (delayed eruption, oligodontia) becomes apparent in this child and causes the parents to bring him to the dentist. Prosthetic appliances are usually indicated and he must be adjusted or be remade as the child matures.