• 제목/요약/키워드: Con-A

검색결과 2,014건 처리시간 0.024초

Changes in growth performance, nutrient digestibility, immune blood profiles, fecal microbial and fecal gas emission of growing pigs in response to zinc aspartic acid chelate

  • Jiao, Yang;Li, Xinran;Kim, In Ho
    • Asian-Australasian Journal of Animal Sciences
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    • 제33권4호
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    • pp.597-604
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    • 2020
  • Objective: This study was conducted to investigate the effect of zinc aspartic acid chelate (Zn-ASP) on growth performance, nutrient digestibility, blood profiles, fecal microbial and fecal gas emission in growing pigs. Methods: A total of 160 crossbred ([Landrace×Yorkshire]×Duroc) growing pigs with an initial body weight (BW) of 25.56±2.22 kg were used in a 6-wk trial. Pigs were randomly allocated into 1 of 4 treatments according to their sex and BW (8 replicates with 2 gilts and 3 barrows per replication pen). Treatments were as follows: i) CON, basal diet, ii) TRT1, CON+0.1% Zn-ASP, iii) TRT2, CON+0.2% Zn-ASP, and iv) TRT3, CON+0.3% Zn-ASP. Pens were assigned in a randomized complete block design to compensate for known position effects in the experimental facility. Results: In the current study, BW, average daily gain, and gain:feed ratio showed significant improvement as dietary Zn-ASP increased (p<0.05) in growing pigs. Apparent total tract digestibility (ATTD) of dry matter was increased linearly (p<0.05) in pigs fed with Zn-ASP diets. A linear effect (p<0.05) was detected for the Zn concentration in blood with the increasing levels of Zn-ASP supplementation. Lactic acid bacteria and coliform bacteria were affected linearly (p<0.05) in pigs fed with Zn-ASP diets. However, no significant differences were observed in the ATTD of nitrogen, energy and Zn. And dietary Zn-ASP supplementation did not affect fecal ammonia, hydrogen sulfide and total mercaptans emissions in growing pigs. Conclusion: In conclusion, dietary supplementation with Zn-ASP of diet exerted beneficial effects on the growth performance, nutrient digestibility, blood profiles and fecal microbes in growing pigs.

The effect of Korean Red Ginseng extract on rosiglitazone-induced improvement of glucose regulation in diet-induced obese mice

  • Oh, Mi-Jeong;Kim, Hyun-Ju;Park, Eun-Young;Ha, Na-Hee;Song, Mun-Gyu;Choi, Sang-Hyun;Chun, Boe-Gwun;Kim, Dong-Hoon
    • Journal of Ginseng Research
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    • 제41권1호
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    • pp.52-59
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    • 2017
  • Background: Korean Red Ginseng extract (KRG, Panax ginseng Meyer) and its constituents have been used for treating diabetes. However, in diet-induced obese mice, it is unclear whether KRG can enhance the glucose-lowering action of rosiglitazone (ROSI), a peroxisome proliferator-activated receptor gamma synthetic activator. Methods: Oral glucose tolerance tests (oGTTs) were performed after 4 days of treatment with a vehicle (CON), KRG [500 mg/kg body weight (b.w.)], ROSI (3.75 mg/kg b.w, 7.5 mg/kg b.w, and 15 mg/kg b.w.), or ROSI and KRG (RK) in obese mice on a high-fat diet. Adipose tissue morphology, crown-like structures (CLSs), and inflammation were compared by hematoxylin-eosin staining or quantitative reverse transcription polymerase chain reaction. Results: The area under the glucose curve (AUC) was significantly lower in the RK group (15 mg/kg b.w. and 500 mg/kg b.w. for ROSI and KRG, respectively) than in the CON group. There was no significant difference in the AUC between the CON and the other groups. Furthermore, the AUC was significantly lower in the RK group than in the ROSI group. The expression of the Ccl2 gene and the number of CLSs were significantly reduced in the RK group than in the CON group. Conclusion: Our results show a potential enhancement of ROSI-induced improvement of glucose regulation by the combined treatment with KRG.

Evaluation of the wound healing ability of an Abeliophyllum distichum Nakai extract in ICR mouse and of antibacterial activity against human cutaneous flora

  • Go, Young Bin;Lee, Ji Hwan;Oh, Han Jin;Kim, Yong Ju;An, Jae Woo;Chang, Se Yeon;Song, Dong Cheol;Cho, Hyun Ah;Cho, Jin Ho
    • 농업과학연구
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    • 제48권3호
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    • pp.567-574
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    • 2021
  • In this study, we evaluated the wound healing rate and, inflammatory cells effects of by Abeliophyllum distichum Nakai (ADN) extract in mice. We also assessed the stability of the ADN extract upon exposure to sunlight. Treatments were as follows: 1) CON (only saline solution), T1 (CON + 0.0125% ADN extract), T2 (CON + 0.05% ADN extract), and T3 (CON + 0.5% ADN extract). A 4 mm punch was used in the central part of the dorsal area to separate it from the subcutaneous tissue, causing a full-thickness skin wound. An amount of 1 mL of each sample was sprayed onto the treatment section of the wound with a pipette every day from the day of wound creation, with proper application ensured using brush. In the stability test, the pH was measured at 1, 4, and 8 weeks after exposing the samples of each treatment section to sunlight considering, the higher concentrations of the ADN extract. The results of this study indicate that the effectiveness of the wound contraction rate in the mice to which the ADN extract was applied was low. Moreover, the stability of the sample containing a high concentration of the ADN extract could not be verified. In addition, no significant results were obtained in the inflammatory reaction assessment. Therefore, additional research focusing on wound contraction, stability, and inflammatory cell outcomes of the ADN extract is needed.

조피볼락(Sebastes schlegelii) 사료 내 합성 비타민C 대체원으로써의 감귤부산물과 발효 감귤부산물의 첨가 효과 (Replacement of Dietary Vitamin C with Citrus and Fermented Citrus By-products in Korean Rockfish Sebastes schlegelii)

  • 신재형;송진우;김민기;임현운;임종호;이경준
    • 한국수산과학회지
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    • 제54권5호
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    • pp.617-623
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    • 2021
  • The study was conducted to investigate the dietary supplementation of citrus by-product (CBP) and CBP fermented with Bacillus subtilis (BS) or B. pumilus (BP) on growth performance, feed utilization, innate immune responses and disease resistance of Korean rockfish Sebastes schlegelii. Triplicate groups of juvenile fish (initial weight of 22.9 g) were fed one of five experimental diets which were formulated to replace a synthetic vitamin C (L-ascorbyl-2-polyphosphate, LAPP) with CBP or fermented CBP. A basal diet without LAPP and CBP was used as the control diet (Con). At the end of the 13 weeks feeding trial, growth performance, feed utilization and survival of fish fed the Con were significantly lower than those of fish fed the LAPP, CBP and fermented CBP diets. Fish fed the Con were significantly lower in lysozyme activity than fish fed LAPP, CBP and fermented CBP diets. In a challenge test against Edwardsiella tarda, cumulative mortality of fish fed LAPP, CBP and fermented CBP diets was significantly lower (20-30%) than that of the Con (60%). The findings in this study indicate that the CBP and/or fermented CBP can be a promising vitamin C source for LAPP replacement in diet for Korean rockfish.

Immune-enhancing effect of hydrolyzed and fermented Platycodon grandiflorum extract in cyclophosphamide-induced immunosuppressed BALB/c mice

  • Hyun Sook Lee;So Mi Kim;Jae In Jung;Jihoon Lim;Moonjea Woo;Eun Ji Kim
    • Nutrition Research and Practice
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    • 제17권2호
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    • pp.206-217
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    • 2023
  • BACKGROUND/OBJECTIVES: The immunomodulatory effect of Platycodon grandiflorum (PG) has been reported, but studies on its mechanism are still lacking. This study was undertaken to confirm whether the hydrolyzed and fermented PG extract (HFPGE) obtained by adding hydrolysis and fermentation to the extraction process has an immune-enhancing effect in the in vivo system. MATERIALS/METHODS: Five-week-old BALB/c mice were divided into 4 groups: normal control group (NOR), control group (CON), 150 mg/kg body weight (BW)/day HFPGE-treated group (T150), and 300 mg/kg BW/day HFPGE-treated group (T300). The mice were administered HFPGE for 4 weeks and intraperitoneally injected with cyclophosphamide (CPA, 80 mg/kg BW/day) on day 6, 7, and 8, respectively, to induce immunosuppression. The levels of immunoglobulins (Igs) and cytokines were measured in the serum. In splenocytes, proliferation and cytokine levels were measured. RESULTS: Serum IgA, IgG, and IgM levels were observed to decrease after CPA treatment, which was recovered by HFPGE administration. The levels of serum interleukin (IL)-12, tumor necrosis factor (TNF)-α, IL-8, and transforming growth factor (TGF)-β were also decreased after exposure to CPA but increased after HFPGE administration. Decreased splenocyte proliferation was seen in CPA-treated mice, but was observed to increase in the T150 and T300 groups as compared to the NOR group. Compared to the CON group, splenocyte proliferation stimulated with concanavalin A (ConA) or lipopolysaccharide (LPS) in the HFPGE-treated groups was significantly increased. The cytokines secreted by ConA-stimulated splenocytes (IL-2, IL-12, interferon-γ, TNF-α) were increased in the T150 and T300 groups, and cytokines secreted by LPS-stimulated splenocytes (IL-4, IL-8, TGF-β) were also increased by HFPGE administration. CONCLUSION: These results suggest that HFPGE stimulates the immunity in immunosuppressed conditions, thereby enhancing the immune response. Therefore, it is expected that HFPGE has the potential to be used as functional food and medicine for immune recovery in various immunocompromised situations.

Characteristics of Purified Horse Oil by Supercritical Fluid Extraction with Different Deodorants Agents

  • Anneke;Hye-Jin Kim;Dongwook Kim;Dong-Jin Shin;Kyoung-tag Do;Chang-Beom Yang;Sung-Won Jeon;Jong Hyun Jung;Aera Jang
    • 한국축산식품학회지
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    • 제44권2호
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    • pp.443-463
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    • 2024
  • This study investigated the impact of activated carbon, palm activated carbon, and zeolite on horse oil (HO) extracted from horse neck fat using supercritical fluid extraction with deodorant-untreated HO (CON) as a comparison. The yield and lipid oxidation of deodorant untreated HO (CON) were not significantly affected by the three deodorants. However, deodorant-treated HOs exhibited significantly elevated levels of α-linolenic acid (C18:3n3) and eicosenoic acid (C20:1n9) compared to CON (p<0.05), while other fatty acids remained consistent. Zeolite-purified HO demonstrated significantly lower levels of volatile organic compounds (VOCs) than other treatments (p<0.05). Remarkably, zeolite decreased the concentration of pentane, 2,3-dimethyl (gasoline odor), by over 90%, from 177.17 A.U. ×106 in CON to 15.91 A.U. ×106. Zeolite also effectively eliminates sec-butylamine (ammonia and fishy odor) as compared to other deodorant-treated HOs (p<0.05). Additionally, zeolite reduced VOCs associated with the fruity citrus flavor, such as nonanal, octanal, and D-limonene in HO (p<0.05). This study suggests that integrating zeolite in supercritical fluid extraction enhances HO purification by effectively eliminating undesirable VOCs, presenting a valuable approach for producing high-quality HO production in the cosmetic and functional food industries.

UAM 초기 운영을 위한 통신 성능 요구도 도출 (Analysis of Communication Performance Requirements for Initial-Phase UAM Services)

  • 정영호;전향식
    • 한국항행학회논문지
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    • 제28권1호
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    • pp.109-115
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    • 2024
  • 도심항공 모빌리티 (UAM; urban air mobility) 서비스를 위한 한국의 K-UAM 운용개념서에서는 초기 운용 과정에서 항공음성통신 뿐만 아니라 4G 및 5G 이동통신의 활용을 고려하고 있다. 본 논문은 UAM 교통관리를 위한 통신 성능 요구사항을 설정하기 위한 방법론을 연구하였으며, 초기 UAM 운항을 위한 통신 성능 요구 항목과 수준을 제시하였다. 이를 위해 K-UAM 운용개념서와 미국 FAA 운용개념서의 UAM 발전 단계별 운영 시나리오를 분석하고, 다양한 UAM 이해관계자 간에 UAM 운용을 위해 전달해야 할 메시지의 종류를 식별하였다. 또한, 이러한 메시지의 전송을 위해 필요한 통신 링크 종류, 데이터 크기, 전송 주기, 허용 가능 지연, 가용성 등을 고려하여 통신 성능 요구사항 초안을 도출하였다. 본 연구 결과는 UAM 서비스를 위한 통신 요구사항 설정 관련 최초 연구로서 향후 UAM 전용 통신망 설계 및 필요 주파수 소요량 산출과 같은 분야에서 유용하게 활용될 것으로 기대된다.

고강도 레미콘 제조에 관한 기초적 연구 (A Fundamental Study on the Making of High Strength Re-Mi-Con)

  • 김광범;김기철;연홍흠;최강순;한천구
    • 한국콘크리트학회:학술대회논문집
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    • 한국콘크리트학회 1994년도 가을 학술발표회 논문집
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    • pp.137-142
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    • 1994
  • This study is aimed for producing the high strength Re-Mi-Con about 400kg/$\textrm{cm}^2$ with Fly-Ash in consideration of the field condition and material in practice. Test results show that compressive strength for 28 days is 300~470kg/$\textrm{cm}^2$ within 30~40% of W/C according to the 15~21cm of target slump.

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Determination of the Effect of Feeding Different Sodium Chloride Regimes on Growth Performance, Viscera Organ Weights and Meat Quality Parameters of Broilers from Hatch to 35 Days of Age

  • Vinothsankar, Geerththana;Macelline, Shemil Priyan;Wickramasuriya, Samiru Sudharaka;Nawarathna, Shan Randima;Ang, Li;Tharangani, Himali;Jayasena, Dinesh Darshaka;Heo, Jung Min
    • 한국가금학회지
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    • 제47권2호
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    • pp.75-82
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    • 2020
  • This study intended to investigate the growth performance and meat quality traits in broilers fed different regimens of NaCl over a period of 35 days. Seven hundred and fifty 1-day-old chicks (Cobb 500) were randomly assigned to five NaCl feeding regimens to obtain three replicates for each regimen. Broilers in CON group were provided with concentrations of 0.35% NaCl for the duration of the experimental period. The other groups were provided with two concentrations of NaCl (0.45% and 0.55%) under two durations, namely: 1) 1~28 d: 0.45% or 0.55% NaCl for 28 days then CON; and 2) 1~35 d: 0.45% or 0.55% NaCl for 35 days. Broilers fed 0.55% NaCl for 1~35 d showed improved (P<0.05) growth performance compared with broilers fed the CON regimen. Moreover, higher water holding capacity of breast meat was shown by the broilers fed 0.55% NaCl for 1~28 d when compared with that in broilers fed the CON diet (P<0.05). Broilers fed 0.45% NaCl showed an increase (P<0.05) in the lightness of the meat over CON diet and the 0.55% NaCl diet. In addition, broilers offered CON had the highest redness value and highest crude ash content in the breast meat (P<0.05). Feeding 0.45% NaCl for 1~35 d and 0.55% NaCl for 1~28 d resulted in a higher (P<0.05) protein content in breast meat. In conclusion, broilers fed diets with 0.55% NaCl for 1~35 d showed improved growth performance as well as water holding capacity and protein content of the breast meat.

유박비료 시비가 수수류의 생육특성 및 건물수량에 미치는 영향 (Effects of Growth Characteristics and Dry Matter Yield of Organic Mixed Expeller Cake Fertilizer in Sorghum-Sudangrass Hybrids)

  • 박만호;김기수
    • 유기물자원화
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    • 제25권4호
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    • pp.23-29
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    • 2017
  • 본 연구는 조사료 생산 분야에서 화학비료를 사용하는 관행농법에서 벗어나 유기재배 기술개발을 위하여 관행재배와 유기재배의 수량성, 사료가치 등을 비교 조사하였다. 시험은 전남 강진군 작천면 소재 축산연구소의 논에서 수행하였다. 유기질 비료로는 질소성분이 4.0% 함유된 유박비료를 이용하였으며, 시험구 편성은 대조구(Con)와 대조구 질소 함량 기준으로 환산하여 유박비료 100% 처리구(T1), 유박비료 150% 처리구(T2), 유박비료200% 처리구(T3)로 구성 하였다. 시험품종은 수수${\times}$수단그라스 교잡종(SX17)을 5월 25일에 ha당 40kg을 휴립세조파(조간 50cm)로 파종하였다. 수확기 처리구별 초장은 대조구 317cm, T1 252cm, T2 269cm, T3 293cm으로 대조구가 가장 우수하였고, 시비 처리구에 따른 시험구에서는 시비량의 증가에 따라 증가하였고, 건초량은 대조구 11.386kg/ha, T1 6,015kg/ha, T2 6,799kg/ha, T3 7,627kg/ha으로 초장의 생육과 동일한 경향을 보였다. 조단백질은 대조구 7.0%, T1 5.7%, T2 6.3%, T3 5.1%로 시험 처리구에서는 T2에서 가장 높았다. 이와 같은 결과로 유박비료를 대조구 시비량 질소 함량 대비 150% 시비에서 사료가치는 유의적 차이를 보이지 않았으나, 초장과 건초량이 증가가 이루어졌으므로 150% 기준으로 시비하는 것이 적합할 것으로 판단된다.