• BMB Reports
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• v.56 no.1
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• pp.43-48
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• 2023

Pre-clinical models are critical in gaining mechanistic and biological insights into disease progression. Recently, patient-derived organoid models have been developed to facilitate our understanding of disease development and to improve the discovery of therapeutic options by faithfully recapitulating in vivo tissues or organs. As technological developments of organoid models are rapidly growing, computational methods are gaining attention in organoid researchers to improve the ability to systematically analyze experimental results. In this review, we summarize the recent advances in organoid models to recapitulate human diseases and computational advancements to analyze experimental results from organoids.

• Journal of The Korean Association of Information Education
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• v.23 no.6
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• pp.639-653
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• 2019

The purpose of this study is to design an instructional framework and cognitive learning environment for AI education based on computational thinking in order to ground the theoretical rationale for AI education. Based on the literature review, the learning model is proposed to select the algorithms and problem-solving models through the abstraction process at the stage of data collection and discovery. Meanwhile, the instructional model of AI education through computational thinking is suggested to enhance the problem-solving ability using the AI by performing the processes of problem-solving and prediction based on the stages of automating and evaluating the selected algorithms. By analyzing the research related to the cognitive learning environment for AI education, the instructional framework was composed mainly of abstraction which is the core thinking process of computational thinking through the transition from the stage of the agency to modeling. The instructional framework of AI education and the process of constructing the cognitive learning environment presented in this study are characterized in that they are based on computational thinking, and those are expected to be the basis of further research for the instructional design of AI education.

• Journal of the Korea Society of Computer and Information
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• v.25 no.5
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• pp.229-241
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• 2020

In this study, we developed a test tool to measure the computational thinking ability of middle school students and investigated their computational thinking power using the tool. The test tool used exploratory factor analysis to examine the computational thinking scales of Korkmaz et al. (2017) and derive suitable factors and questions for middle school students in Korea. The developed test tool was applied to 492 middle school students to analyze differences in computational thinking ability according to gender, grade, programming experience, type of programming language, and interest. According to the study, male Korean middle school students had higher computing power than females. In addition, students who had programming experience or used text-based rather than block-based programming languages demonstrated higher computational thinking. There was no significant difference in the computational thinking of middle school students according to grade, and the level of interest in artificial intelligence only had a slight influence on computational thinking.

• Journal of Information Processing Systems
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• v.9 no.4
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• pp.633-650
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• 2013

All the imputation techniques proposed so far in literature for data imputation are offline techniques as they require a number of iterations to learn the characteristics of data during training and they also consume a lot of computational time. Hence, these techniques are not suitable for applications that require the imputation to be performed on demand and near real-time. The paper proposes a computational intelligence based architecture for online data imputation and extended versions of an existing offline data imputation method as well. The proposed online imputation technique has 2 stages. In stage 1, Evolving Clustering Method (ECM) is used to replace the missing values with cluster centers, as part of the local learning strategy. Stage 2 refines the resultant approximate values using a General Regression Neural Network (GRNN) as part of the global approximation strategy. We also propose extended versions of an existing offline imputation technique. The offline imputation techniques employ K-Means or K-Medoids and Multi Layer Perceptron (MLP)or GRNN in Stage-1and Stage-2respectively. Several experiments were conducted on 8benchmark datasets and 4 bank related datasets to assess the effectiveness of the proposed online and offline imputation techniques. In terms of Mean Absolute Percentage Error (MAPE), the results indicate that the difference between the proposed best offline imputation method viz., K-Medoids+GRNN and the proposed online imputation method viz., ECM+GRNN is statistically insignificant at a 1% level of significance. Consequently, the proposed online technique, being less expensive and faster, can be employed for imputation instead of the existing and proposed offline imputation techniques. This is the significant outcome of the study. Furthermore, GRNN in stage-2 uniformly reduced MAPE values in both offline and online imputation methods on all datasets.

• Journal of The Korean Association of Information Education
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• v.25 no.5
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• pp.751-759
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• 2021

This study developed an artificial intelligence education program using localized public data as an educational method for improving computing thinking skills of elementary school students. According to the ADDIE model, the program design was carried out based on the results of pre-requisite analysis for elementary school students, and textbooks and education programs were developed. Based on localized public data, the training program was constructed to learn the principles of artificial intelligence using machine learning for kids and scratches and to solve problems and improve computational thinking through abstracting public data for purpose. It is necessary to put this training program into the field through further research and verify the change in students' computational thinking as a result.

• Journal of the Institute of Convergence Signal Processing
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• v.22 no.3
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• pp.110-115
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• 2021

With the era of the 4th Industrial Revolution, education on artificial intelligence is one of the important topics. However, since existing education is aimed at knowledge, it is not suitable for developing the active problem-solving ability and AI utilization ability required by artificial intelligence education. To solve this problem, we proposes PBL-based education method in which learners learn in the process of solving the presented problem. The problem presented to the learner is a completed project. This project consists of three types: a classification model, the training data of the classification model, and the block code to be executed according to the classified result. The project works, but each component is designed to perform a low level of operation. In order to solve this problem, the learners can expect to improve their computational thinking skills by finding problems in the project through testing, finding solutions through discussion, and improving to a higher level of operation.

• Journal of The Korean Association of Information Education
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• v.25 no.6
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• pp.917-925
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• 2021

This study aims to specify a constructivism-based instructional method using a modular data analysis tool. The value and meaning of a modular data analysis tool have been examined to be applied in the national curriculum for artificial intelligence education and the process of cultivating problem-solving ability based on computational thinking. The modular data analysis tool visually expresses the cognitive thinking process that forms the schema in equilibrating through assimilation and adjustment. Artificial intelligence education has features that embody abstract knowledge and structure the data analysis module through the represented schema as a BlackBox implemented as an algorithm. Therefore, the value of the modular data analysis tool could be examined because it has the advantage of connecting the conceptual and implicit schema.

• 한국정보교육학회:학술대회논문집
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• 2021.08a
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• pp.253-259
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• 2021

In line with the modern society where artificial intelligence has spread throughout society, the Ministry of Education decided to provide AI education in kindergartens, elementary, middle and high school classes in 2025, and develop related learning materials and textbooks from 2021. Korea currently does not have state-led AI education for kindergarten and elementary school, so there is no systematic teaching material. Therefore, this study designed and presented textbooks for pattern analysis-based computational thinking development based on the GPS curriculum, a kindergarten SW curriculum studied by Y. S. Jeong and S. E. Lim (2020). Class procedures for using the textbooks were classified as introduction activities, development activities, and organization activities. Supplementary explanations were presented by presenting textbooks and teaching aids along with explanations of each activity. In order for this study to help AI education conducted in 2025, research must be conducted to demonstrate its effectiveness through actual application in the future.

• The Mathematical Education
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• v.63 no.2
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• pp.209-231
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• 2024

The education sector is undergoing significant changes due to the Fourth Industrial Revolution and the advancement of artificial intelligence. Particularly, the importance of education based on artificial intelligence is being emphasized. Accordingly, the purpose of this study is to develop a statistics education program using deep learning prediction in high school mathematics and to examine the impact of such statistically problem-solvingcentered statistics education programs on high school students' statistical literacy and computational thinking. To achieve this goal, a statistics education program using deep learning prediction applicable to high school mathematics was developed. The analysis revealed that students' understanding of context improved through experiencing how data was generated and collected. Additionally, they enhanced their comprehension of data variability while exploring and analyzing various datasets. Moreover, they demonstrated the ability to critically analyze data during the process of validating its reliability. In order to analyze the impact of the statistics education program on high school students' computational thinking, a paired sample t-test was conducted, confirming a statistically significant difference in computational thinking between before and after classes (t=-11.657, p<0.001).

• Journal of The Korean Association of Information Education
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• v.25 no.5
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• pp.705-712
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• 2021

This study aims to develop artificial intelligence education programs that can be easily applied in elementary schools according to the trend of the times called artificial intelligence. The training program designed the purpose and direction based on the analysis results of the needs of 70 elementary school teachers according to the steps of the ADDIE model. According to the survey, elementary school students developed a machine learning education program to set sound data as the theme of the most accessible in their daily lives and to learn the principles of artificial intelligence in solving problems using sound data in real life. These days, when the need for artificial intelligence education emerges, elementary machine learning education programs that solve daily life problems based on sound data developed in this study will lay the foundation for elementary artificial intelligence education.