• 제목/요약/키워드: Computational and experimental methods

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이스트 프로테옴에 대한 단백질-단백질 네트워크의 생물학적 및 물리학적 정보인식 : 라플라스 행렬에 대한 고유치와 섭동분석 (Identifying the biological and physical essence of protein-protein network for yeast proteome : Eigenvalue and perturbation analysis of Laplacian matrix)

  • Chang, Ik-Soo;Cheon, Moo-Kyung;Moon, Eun-Joung;Kim, Choong-Rak
    • 한국생물정보학회:학술대회논문집
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    • 한국생물정보시스템생물학회 2004년도 The 3rd Annual Conference for The Korean Society for Bioinformatics Association of Asian Societies for Bioinformatics 2004 Symposium
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    • pp.265-271
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    • 2004
  • The interaction network of protein -protein plays an important role to understand the various biological functions of cells. Currently, the high -throughput experimental techniques (two -dimensional gel electrophoresis, mass spectroscopy, yeast two -hybrid assay) provide us with the vast amount of data for protein-protein interaction at the proteome scale. In order to recognize the role of each protein in their network, the efficient bioinformatical and computational analysis methods are required. We propose a systematic and mathematical method which can analyze the protein -protein interaction network rigorously and enable us to capture the biological and physical essence of a topological character and stability of protein -protein network, and sensitivity of each protein along the biological pathway of their network. We set up a Laplacian matrix of spectral graph theory based on the protein-protein network of yeast proteome, and perform an eigenvalue analysis and apply a perturbation method on a Laplacian matrix, which result in recognizing the center of protein cluster, the identity of hub proteins around it and their relative sensitivities. Identifying the topology of protein -protein network via a Laplacian matrix, we can recognize the important relation between the biological pathway of yeast proteome and the formalism of master equation. The results of our systematic and mathematical analysis agree well with the experimental findings of yeast proteome. The biological function and meaning of each protein cluster can be explained easily. Our rigorous analysis method is robust for understanding various kinds of networks whether they are biological, social, economical...etc

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RANS법을 이용한 선박 프로펠러 날개 끝 보오텍스 유동 해석 (RANS ANALYSES OF THE TIP VORTEX FLOW OF A MARINE PROPELLER)

  • 박일룡
    • 한국전산유체공학회지
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    • 제21권2호
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    • pp.62-69
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    • 2016
  • It has been highly demanded to improve the accuracy of CFD(Computational Fluid Dynamics) methods for the assessment of the hydrodynamic performance of marine propellers in cavitating and non-cavitating flows. This paper presents a validation study on the numerical simulation of the tip vortex flow of a non-cavitating marine propeller SVA VP1304. The calculations are carried out by using the Reynolds averaged Navier-Stokes(RANS) approach, where the Reynolds Stress Model(RSM) is used for turbulence closure. The present paper contains a grid dependence test for the propeller open water simulations and a special emphasis is placed on conducting a local grid adaptation on the blade tip and in the tip vortex to reasonably reproduce the velocity and the pressure in the tip vortex flow field. The numerical results are compared with the experimental validation data, which are published in the second International Symposium on Marine Propulsors 2011(SMP'11). The present numerical results show a reasonable agreement with the experiments.

CAA를 이용한 2D 원형 실린더 공력 소음 해석 (TWO-DIMENSIONAL COMPUTATIONAL AEROACOUSTICS SIMULATION OF SOUND GENERATED BY FLOW AROUND A CIRCULAR CYLINDER)

  • 박인철;고영주;최종수;김병수
    • 한국전산유체공학회지
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    • 제18권1호
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    • pp.22-27
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    • 2013
  • Researches in the area of aeroacoustics have been conducted by two methods. In the first method theoretical formula or experimentation are utilized, and in the second method flow field analysis and acoustic analogy are utilized. In contrast to the first method, the second method does not need new experiments for every individual change of flow configurations and conditions, and it can predict their effects by the flow field analysis, which makes the second method preferred than the first one. In this paper numerical analysis to predict noise generated by a turbulent flow about a two dimensional circular cylinder by use of CAA (Computational Aeroacoustics) method is conducted and the results are compared to the available experimental data.

실험적 모드해석을 이용한 다물체계내 유연체의 변형보드 계산 (Computation for Deformation Modes of a Flexible Body in Multibody System using Experimental Modal Analysis)

  • 김효식;김상섭
    • 대한기계학회:학술대회논문집
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    • 대한기계학회 2003년도 추계학술대회
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    • pp.1718-1723
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    • 2003
  • This paper presents a computational method for deformation modes of a flexible body in multibody system from the experimental modal analysis and an efficient method for flexible multibody dynamic analysis by use of the modes. It is difficult to directly use experimental modal parameters in flexible multibody dynamic analysis. The major reasons are that there are many inconsistencies between experimental and analytical modal data and experimental noises are inherent in the experimental data. So two methods, such as, a method for ortho-normalization of experimental modes and the other one for mode expansion, are suggested to gain deformation modes of a flexible body from the experimental modal parameters. Using the virtual work principle, the equation of motion of a flexible body is derived. The effectiveness of the proposed method will be verified in the numerical example of cab vibration of a truck by comparing analysis and test results.

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탈착식 자전거 캐리어용 흡착 패드의 실험 및 전산적 방법을 활용한 구조해석 (Structural Analysis of a Suction Pad for a Removable Bike Carrier using Computational and Experimental Methods)

  • 서영성;임근원
    • 한국산학기술학회논문지
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    • 제17권3호
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    • pp.622-628
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    • 2016
  • 자동차에 부착하여 사용하는 자전거 캐리어 지지용 흡착 패드는 운행 중 임의의 진동과 원심력과 같은 과도한 동적 하중을 받을 수 있어, 구조 안전성의 검토가 중요하다. 이를 위해서는 유체-구조 연계 유한요소해석을 이용하여 패드의 하부 압력이 패드에 가해지는 하중이나 모멘트의 변화에 따라 실시간으로 변화하는 것을 고려하여야 하나, 실제 상황의 모델링이 어렵고 계산을 위한 소프트웨어 비용이 높은 단점이 있기도 하지만, 정확한 결과를 얻기도 어렵다. 따라서 이 논문에서는 실험과 전산적인 방법을 조합하여 활용하는 새로운 방법을 제시한다. 이는 변화하는 하중에 따라 패드 하부의 압력과 접촉 면적을 실시간으로 측정하고 여기서 얻어진 데이터를 비선형 탄성 유한요소해석에 입력하여 활용하는 방법이다. 개발 단계의 제품 형상으로 실험 및 계산을 수행한 결과, 마운트 패드는 축 방향 하중에 대해서는 비교적 안전하나, 회전 하중이 과도하게 작용할 경우 패드가 바닥으로부터 분리되거나 패드 표면에 국부적인 손상이 일어날 수 있어 안전 여유가 많지 않음을 보여주었다. 작용하는 하중의 크기 및 형태에 따라 변화하는 접촉 거동을 예측하는 결과는 실험 결과와 잘 일치하였다. 본 연구에서 제안하는 해석 방법은 유사한 흡착 패드 시스템을 설계할 때 유용하게 활용될 수 있을 것으로 보인다.

Verification of CFD analysis methods for predicting the drag force and thrust power of an underwater disk robot

  • Joung, Tae-Hwan;Choi, Hyeung-Sik;Jung, Sang-Ki;Sammut, Karl;He, Fangpo
    • International Journal of Naval Architecture and Ocean Engineering
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    • 제6권2호
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    • pp.269-281
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    • 2014
  • This paper examines the suitability of using the Computational Fluid Dynamics (CFD) tools, ANSYS-CFX, as an initial analysis tool for predicting the drag and propulsion performance (thrust and torque) of a concept underwater vehicle design. In order to select an appropriate thruster that will achieve the required speed of the Underwater Disk Robot (UDR), the ANSYS-CFX tools were used to predict the drag force of the UDR. Vertical Planar Motion Mechanism (VPMM) test simulations (i.e. pure heaving and pure pitching motion) by CFD motion analysis were carried out with the CFD software. The CFD results reveal the distribution of hydrodynamic values (velocity, pressure, etc.) of the UDR for these motion studies. Finally, CFD bollard pull test simulations were performed and compared with the experimental bollard pull test results conducted in a model basin. The experimental results confirm the suitability of using the ANSYS-CFX tools for predicting the behavior of concept vehicles early on in their design process.

가상환경기반 원격작업자 시각지원시스템 개발 및 시험 (Development and Test of the Remote Operator Visual Support System Based on Virtual Environment)

  • 송태길;박병석;최경현;이상호
    • 한국CDE학회논문집
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    • 제13권6호
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    • pp.429-439
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    • 2008
  • With a remote operated manipulator system, the situation at a remote site can be rendered through remote visualized image to the operator. Then the operator can quickly realize situations and control the slave manipulator by operating a master input device based on the information of the virtual image. In this study, the remote operator visual support system (ROVSS) was developed for viewing support of a remote operator to perform the remote task effectively. A visual support model based on virtual environment was also inserted and used to fulfill the need of this study. The framework for the system was created by Windows API based on PC and the library of 3D graphic simulation tool such as ENVISION. To realize this system, an operation test environment for a limited operating site was constructed by using experimental robot operation. A 3D virtual environment was designed to provide accurate information about the rotation of robot manipulator, the location and distance of operation tool through the real time synchronization. In order to show the efficiency of the visual support, we conducted the experiments by four methods such as the direct view, the camera view, the virtual view and camera view plus virtual view. The experimental results show that the method of camera view plus virtual view has about 30% more efficiency than the method of camera view.

반복하중을 받는 강재 브레이싱의 거동에 관한 해석적 연구 (A Study on the Analysis of Steel Bracing Behaviour Subjected to Cyclic Loads)

  • 구민세;김병석;김일곤
    • 전산구조공학
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    • 제2권3호
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    • pp.69-75
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    • 1989
  • 브레이싱재를 사용하는 목적은 본 골조체계 즉 기둥과 보에 비해 단면(강성)이 작은 부재로 보강하여 횡력에 대한 강성효과를 크게 향상시키기 위함이다. 브레이싱재의 단면이 기둥과 보의 단면에 비해 월등히 작기 때문에 압축력에 의한 좌굴의 위험성과 휨량의 크기에 비례하여 부재 중앙에 발생되는 추가 모멘트(P-.DELTA. Effect)에 의한 불리한 영향 및 해석상의 어려움 때문에 브레이싱의 설계에 있어서 브레이싱재는 압축력을 받지 않는 것으로 간주하여 왔다. 그러나 최근 들어 구조물 해석에 정확도가 요구되어짐에 따라 브레이싱재의 정확한 거동에 대한 연구가 실험을 통해 활발히 진행되어 왔고, 특히 탄성한계를 지난 소성상태에서 반복하중에 의한 거동 규명이 큰 관심을 끌고 있다. 본 논문에서는 반복하중을 받는 강재 브레이싱재의 비선형 거동을 해석적 방법에 의해 규명했고, 그 결과를 실험결과와 비교하였다.

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Micromechanical failure analysis of composite materials subjected to biaxial and off-axis loading

  • Ahmadi, Isa
    • Structural Engineering and Mechanics
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    • 제62권1호
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    • pp.43-54
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    • 2017
  • In this study, the failure behavior of composite material in the biaxial and off-axis loading is studied based on a computational micromechanical model. The model is developed so that the combination of mechanical and thermal loading conditions can be considered in the analysis. The modified generalized plane strain assumption of the theory of elasticity is used for formulation of the micromechanical modeling of the problem. A truly meshless method is employed to solve the governing equation and predict the distribution of micro-stresses in the selected RVE of composite. The fiber matrix interface is assumed to be perfect until the interface failure occurs. The biaxial and off-axis loading of the SiC/Ti and Kevlar/Epoxy composite is studied. The failure envelopes of SiC/Ti and Kevlar/Epoxy composite in off-axis loading, biaxial transverse-transverse and axial-transverse loading are predicted based on the micromechanical approach. Various failure criteria are considered for fiber, matrix and fiber-matrix interface. Comparison of results with the available results in the litreture shows excellent agreement with experimental studies.

Ramp Edge Detection을 이용한 끝점 검출과 음절 분할에 관한 연구 (A Study on Endpoint Detection and Syllable Segmentation System Using Ramp Edge Detection)

  • 유일수;홍광석
    • 대한전자공학회:학술대회논문집
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    • 대한전자공학회 2003년도 하계종합학술대회 논문집 Ⅳ
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    • pp.2216-2219
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    • 2003
  • Accurate speech region detection and automatic syllable segmentation is important part of speech recognition system. In automatic speech recognition system, they are needed for the purpose of accurate recognition and less computational complexity, In this paper, we Propose improved syllable segmentation method using ramp edge detection method and residual signal Peak energy. These methods were used to ensure accuracy and robustness for endpoint detection and syllable segmentation system. They have almost invariant response to various background noise levels. As experimental results, we obtained the rate of 90.7% accuracy in syllable segmentation in a condition of accurate endpoint detection environments.

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