• Food Science of Animal Resources
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• v.34 no.6
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• pp.836-843
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• 2014

Obesity, a condition in which an abnormally large amount of fat is stored in adipose tissue, causing an increase in body weight, has become a major public health concern worldwide. The purpose of this study was to optimize the process for fermented milk for the production of a functional product with an anti-obesity effect by using Lactobacillus plantarum Q180 isolated from human feces. We used a 3-factor, 3-level central composite design (CCD) combined with the response surface methodology (RSM). Concentration of skim milk powder (%, $X_1$), incubation temperature ($^{\circ}C$, $X_2$), and incubation time (h, $X_3$) were used as the independent factors, whereas pH (pH, $Y_1$), anti-lipase activity (%, $Y_2$) and anti-adipogenetic activity (%, $Y_3$) were used as the dependent factors. The optimal conditions of fermented milk for the highest anti-lipase and anti-adipogenetic activity with pH 4.4 were the 9.5% of skim milk powder, $37^{\circ}C$ of incubation temperature, 28 h of incubation time. In the fermentation condition, the predicted values of pH, anti-lipase activity and anti-adipogenetic activity were 4.47, 55.55, and 20.48%, respectively. However, the actual values of pH, anti-lipase activity and anti-adipogenetic activity were 4.50, 52.86, and 19.25%, respectively. These results demonstrate that 9.5% of skim milk powder and incubation at $37^{\circ}C$ for 28 h were the optimum conditions for producing functional fermented milk with an anti-obesity effect.

• Composites Research
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• v.33 no.4
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• pp.185-190
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• 2020

Titanium is widely used as an implant material due to its excellent biocompatibility, but has a problem due to high cost and high Young's modulus compared to bone. Magnesium alloy is attracting attention as a material to replace it. Magnesium alloy, like titanium, has excellent biocompatibility and has a Young's modulus similar to that of bone. However, there are corrosion resistance problems due to corrosion, and various surface treatment methods are being studied to solve them. In this study, the ceramic coating layer was grown on the surface of the AZ31 magnesium alloy in an electrolytic solution containing EDTA, and the properties of the formed coating were analyzed through SEM and XRD to analyze the microstructure and shape, and measured the micro hardness of the coating layer. Corrosion properties in the body were evaluated through a corrosion test in SBF solution, a component similar to blood plasma.

• Proceedings of the KSME Conference
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• 2004.04a
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• pp.204-209
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• 2004

SiC materials have been extensively studied for high temperature components in advanced energy system and advanced gas turbine. However, the brittle characteristics of SiC such as low fracture toughness and low strain-to fracture still impose a severe limitation on practical applications of SiC materials. For these reasons, $SiC_f/SiC$ composites can be considered as a promising for various structural materials, because of their good fracture toughness compared with monolithic SiC ceramics. But, high temperature and pressure lead to the degradation of the reinforcing fiber during the hot pressing. Therefore, reduction of sintering temperature and pressure is key requirements for the fabrication of $SiC_f/SiC$ composites by hot pressing method. In the present work, Monolithic LPS-SiC was fabricated by hot pressing method in Ar atmosphere at 1760 $^{\circ}C$, 1780 $^{\circ}C$, 1800 $^{\circ}C$ and 1820 $^{\circ}C$ under 20 MPa using $Al_2O_3-Y_2O_3$ system as sintering additives in order to low sintering temperature. The starting powder was high purity ${\beta}-SiC$ nano-powder with an average particle size of 30 nm. Monolithic LPS-SiC was evaluated in terms of sintering density, micro-structure, flexural strength, elastic modulus and so on. Sintered density, flexural strength and elastic modulus of fabricated LPS-SiC increased with increasing the sintering temperature. In the micro-structure of this specimen, it was found that grain of sintered body was grown from 30 nm to 200 nm.

• Journal of the Korean Geosynthetics Society
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• v.2 no.3
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• pp.11-18
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• 2003

The one of the most important concerns in the design of the final cover system is to restrict percolation of water into the waste body. To minimize entering the water, the final cover system has the barrier layer that consists of a single compacted clay liner(CCL) or a composite liner with high density polyethylene(HDPE) overlying CCL. The HDPE as well as CCL can be damaged by landfill settlements. Therefore, this study was conducted to assess the effects of HDPE induced by settlements in the final cover system after closure. The results of the three test that is field test, lysimeter test in laboratory, and prediction of settlement represent that the HDPE in the final cover system is not pretty much affected by settlements and stable on settlements.

• Korean Journal of Pharmacognosy
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• v.44 no.3
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• pp.291-297
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• 2013

Sophorae Flos (SF), a composite of flowers and flower-buds of Sophora japonica, has long been used in traditional Korean and Chinese medicines for the treatment of hemostasis and inflammation. In this study, we investigated anti-inflammatory effect of four EtOH extracts at the difference in blooming stages of flowers on LPS-induced inflammation in RAW264.7 cells. We classified the flowers of Sophora japonica with SF-1 (length of flower is shorter than calyx), SF-2 (length of calyx is shorter than flower), SF-3 (full bloom), and SF-4 (not blooming at all). We examined HPLC analysis, whether quercetin and rutin are major component of these Sophorae Flos extracts or not. As a result, SF-1 contained quercetin, but the others did not. In addition, quercetin, SF-1, and SF-4 act on the suppression of pro-inflammatory mediators including inducible nitric oxide synthase (iNOS), cyclooxygenase (COX)-2, nitric oxide (NO), prostaglandin E2 ($PGE_2$) against lipopolysaccharide (LPS)-induced activation in RAW264.7 cells. Of these, SF-1 showed the best anti-inflammatory effect. These results suggest that Sophorae Flos with the highest content of quercetin would be used for the treatment of various inflammation diseases.

• Korean Journal of Metals and Materials
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• v.50 no.5
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• pp.401-406
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• 2012

When viewed using a magnetic resonance imaging (MRI) system, invasive materials inside the human body, in many cases, severely distort the MR image of human tissues. The degree of the MR image distortion increases in proportion not only to the difference in the susceptibility between the invasive material and the human tissue, but also to the intensity of the magnetic field induced by the MRI system. In this study, by blending paramagnetic Ti particles with diamagnetic graphite, we synthesized $Ti_{100-x}C_x$ composites that can reduce the artifact in the MR image under the high-strength magnetic field. Of the developed composites, $Ti_{70}C_{30}$ showed the magnetic susceptibility of ${\chi}=67.6{\times}10^{-6}$, which corresponds to 30% of those of commercially available Ti alloys, the lowest reported in the literature. The level of the MR image distortion in the vicinity of the $Ti_{70}C_{30}$ composite insert was nearly negligible even under the high magnetic field of 4.7 T. In this paper, we reported on a methodology of designing new structural materials for bio-applications, their synthesis, experimental confirmation and measurement of MR images.

• Smart Structures and Systems
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• v.24 no.6
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• pp.723-732
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• 2019

Globally road transport networks are subjected to continuous levels of stress from increasing loading and environmental effects. As the most popular mean of transport in the UK the condition of this civil infrastructure is a key indicator of economic growth and productivity. Structural Health Monitoring (SHM) systems can provide a valuable insight to the true condition of our aging infrastructure. In particular, monitoring of the displacement of a bridge structure under live loading can provide an accurate descriptor of bridge condition. In the past B-WIM systems have been used to collect traffic data and hence provide an indicator of bridge condition, however the use of such systems can be restricted by bridge type, assess issues and cost limitations. This research provides a non-contact low cost AI based solution for vehicle classification and associated bridge displacement using computer vision methods. Convolutional neural networks (CNNs) have been adapted to develop the QUBYOLO vehicle classification method from recorded traffic images. This vehicle classification was then accurately related to the corresponding bridge response obtained under live loading using non-contact methods. The successful identification of multiple vehicle types during field testing has shown that QUBYOLO is suitable for the fine-grained vehicle classification required to identify applied load to a bridge structure. The process of displacement analysis and vehicle classification for the purposes of load identification which was used in this research adds to the body of knowledge on the monitoring of existing bridge structures, particularly long span bridges, and establishes the significant potential of computer vision and Deep Learning to provide dependable results on the real response of our infrastructure to existing and potential increased loading.

• Composites Research
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• v.32 no.2
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• pp.120-126
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• 2019

Advanced fiber fabrics have been utilized in not only anti-stabbing and bullet-proofing for body armor but also various industrial fields including vehicular armor and spacecraft structure. Furthermore, there have been a number of research to improve the ballistic performance of advanced fabrics introducing many computational approaches. In our research, an advanced fabric, Heracron manufactured in South Korea was modelled firstly using Autodyn, a commercial software specializing in impact and explosion phenomenon. The sensitivity of the input parameters was also confirmed by conducting simulations. To verify the numerical modelling, we measured and compared the simulation results with velocity decrements after impact involving one, three, and five layers of Heracron under 200-500 m/s impacts by an aluminum spherical projectile. The Heracron fabric was successfully modelled using Autodyn.

• Composites Research
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• v.34 no.3
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• pp.161-166
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• 2021

In this study, we present a research method to develop a shoe that prevents foot injury by inducing the foot pressure. An orthogonal grid sensor was used to check the foot pressure in the upright standing position, and the change in the foot pressure distribution for various conditions was compared. We checked the conditions for distributing foot pressure efficiently by changing the spring constant of the spring inserted into the sole of the shoe and the foot pressure generated with or without the arch of the insole. In order to minimize the experimental error from the randomness of the human body's behavior, it is possible to predict through foot pressure under certain conditions through finite element analysis that simulates the pressure distribution. By checking the change of foot pressure according to the number and arrangement of springs through finite element analysis, conditions were established to provide more efficient foot pressure. The result can be used for designing footwear for patients with diabetic feet.

• The Journal of Korean Physical Therapy
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• v.34 no.3
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• pp.121-127
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• 2022

Purpose: This study aims to compare the effect on balance during core and ankle muscle strengthening exercises using the Thera-Band. Methods: 21 healthy college students were recruited. The participants were divided into a core strengthening group (CSG), an ankle strengthening group (ASG), and a non-exercise group (NEG). CSG and ASG were performed twice a week for a total of 4 weeks, and static and dynamic balance were measured before and after the intervention. The static balance were measured as stability index and weight distribution index using Tetrax^®. The dynamic balance was measured in each direction by the Y balance test. The Thera-Band intensity was increased after 2 weeks of exercise, and the exercise was subsequently performed. Results: Participants showed static balance with Tetrax^®, a significant difference was noted between normal eye closes and pillow with eye closes in ASG (p<0.05). In the case of dynamic balance with the Y balance test, a significant difference was observed in posterolateral direction (PL) and composite score (CS) between each group for the pre- and post-intervention differences (p<0.05). A significant difference was observed between PL and CS in CSG (p<0.05). Conclusion: These findings show that the progressive Thera-Band exercise had a positive effect on balance abilities. It was confirmed that core strengthening was effective for dynamic balance, and ankle strengthening was effective for static balance.