• Food Science and Preservation
• /
• v.22 no.1
• /
• pp.19-26
• /
• 2015

Indole 3-carbinol (I3C), important component of cruciferous vegetables and its major acid-catalyzed metabolite, 3,3'-diindolylmethane (DIM) have been suggested to have an inhibitory effect on the tumor growth and metastasis. This study investigated the effect of DIM on the adhesion, migration and invasion of highly invasive PC3 and DU145 human prostate cancer cell lines. Cells were grown in Dulbecco's modified Eagle's medium (DMEM) supplemented with 3.0 g/L glucose, 3.7 g/L sodium bicarbonate and 10% fetal bovine and were incubated in a humidified incubator at $37^{\circ}C$ and 5% $CO_2$. DIM reduced the adhesion of PC3 and DU145 cells in a dose dependent manner. The pretreatment of PC3 cells with DIM reduced the adhesion dose dependantly, but inhibition was less effective than the treatment with DIM during the adhesion assay. The migration and invasion of PC3 and DU145 cells were reduced by DIM dose dependantly, and the inhibition of DIM was less effective in the DU145 cells than in the PC3 cells. The pretreatment of PC3 cells with DIM for 24 hr before the assay reduced invasion of PC3 cells by 37%. These results suggest that DIM inhibits adhesion, migration and invasion of the PC3 and DU145 cells and may be an effective antimetastatic therapy in addition to traditional chemotherapy.

• Korean Journal of Environment and Ecology
• /
• v.21 no.2
• /
• pp.134-140
• /
• 2007

The purpose of this study is to investigate the landscape image and visual preference for ridges of the Seongpanak district at Mt. Hallasan. For this, the evaluation of the artificial and natural landscape is compared through the medium of color slides. Data is analyzed through the descriptive statistics and spatial image is analyzed by factor analysis algorithm. Principle component analysis and Varimax Method are applied to extraction and factor rotation respectively. The results of this study can be summarized as follows : General visual imagesthe Seongpanak district at Mt. Hallasan are clean, beautiful and attractive. The degree of visual preference increased commensurately with the lower rate of artificial factors. Landscape Factors covering the spatial image are found to be 'aesthetic value', 'spatial scale', 'natural quality', and 'topography' factor, which account for 57.6% of the total variants. The aesthetic value variable is the most important factor in visual preference and the unnatural factors are found to present negative elements with visual preference.

• The Journal of the Korea Contents Association
• /
• v.21 no.4
• /
• pp.303-316
• /
• 2021

This study is aimed at verifying the effects of an ETC(Expressive Therapies Continuum)-based group art therapy program on reducing parental anxiety in first-grade elementary school students' mothers. An ETC program was composed based on the therapeutic factors of the ETC components. Seven mothers of first-grade students located in city A of Gyeonggi-do were selected as the subjects of the study. These mothers underwent 11 sessions of ETC-based group art therapy from April 18 to May 24, 2019, 1 to 2 times a week for 70 to 90 minutes. In order to verify the effectiveness of this research program, scores from pre- and post-parental anxiety scales were analyzed using SPSS 24.0 program. Results demonstrated that first, mothers' parental anxiety was significantly reduced after the ETC program participation. Second, changes in ETC component use throughout the program positively influenced reductions in parental anxiety. In conclusion, each participant experienced the opportunity to self-explore and self-understand at all levels of ETC with their preferred art medium, thereby lowering parenting anxiety. It is meaningful that through the ETC-based art therapy program, the client can be self-aware of his or her problem, and the client can decide the direction that is beneficial to them through voluntary media selection. In addition, it is meaningful that the ETC group art therapy is able to perform activities tailored to each individual.

• Journal of Advanced Technology Convergence
• /
• v.3 no.2
• /
• pp.25-31
• /
• 2024

In recent industrialization and development due to information and communication technology, modern women in modern society are exposed to physical and mental health due to numerous stresses. Popular inflammations are attributable to a decrease in lactic acid bacteria, frequent antibiotic use, and a decrease in immunity. It is necessary to develop products that are helpful and reflected. The inner care gel currently introduced on the market can increase beneficial bacteria and maintain a healthy y-zone. The inner gel contains a hydrogel component. 90% is made up of water, and other components act as support for supporting water and are formed through crosslinking between polymer chains. Hydroxyethyl cellulose (HEC) is a hydroxyethyl ethylenetel of cellulose. The purpose of use is to act as a binder, an emulsion stabilizer, a viscosity enhancer (water-soluble), and a film forming agent. CA (crosslinker) is a crosslinking agent and serves to bind. Hydrogel in the beauty field acts as a film forming agent that gently wraps around the skin by forming a thin film and serves as an emulsion stabilizer that helps to prevent separation of other raw materials. It also acts as a thickener by increasing viscosity in cosmetics. In addition, it is used for glucose monitoring, nursing care, cell transplantation, and wound treatment in the bio field. Currently, it is understood that no products using functional hydrogel have been released, so in this study, a Y zone care hydrogel solution was manufactured to find out the antibacterial properties of the functional hydrogel, and a new solution was developed. As a result, it was confirmed that the appropriate Ph was applied to the Y zone, and after culturing Candida albicans in PDB medium, all three products of the Y zone care hydrogel solution showed an antibacterial effect of 0.5-1.0mm

• The Journal of the Convergence on Culture Technology
• /
• v.8 no.5
• /
• pp.71-80
• /
• 2022

The purpose of this study was to evaluate the effects of the non-pharmacological intervention on depressive symptoms in the older adults with mild cognitive impairment. A total of 1,147 studies were retrieved from PubMed, CINAHL, PsycINFO, Science direct, KISS, RISS, and DBPia. Twenty-one studies which met the criteria were selected and the quality assessment was conducted independently by two investigators. The effect size of non-pharmacological intervention was estimated using Comprehensive Meta-Analysis 3.0. The overall effect size turned out to be the medium effect size (Hedges' g=-0.68, 95% CI=-1.01~-0.36). As a result of the subgroup analysis, the intervention type was statistically significant. The effect size of cognitive intervention (Hedges' g=-1.03, 95% CI=-1.43~-0.61) and multi component intervention (Hedges' g=-0.97, 95% CI=-1.63~-0.33) was greater than excise intervention (Hedges' g=-0.53, 95% CI=-1.16~0.03). This study shows that non-pharmacological intervention was also effective in reducing depressive symptoms in the older adults with mild cognitive impairment. Based on the research results, it is expected that various non-pharmacological intervention studies will be attempted to improve cognitive function and depressive symptoms of the older adults with mild cognitive impairment.

• Asia-Pacific Journal of Business Venturing and Entrepreneurship
• /
• v.18 no.6
• /
• pp.41-55
• /
• 2023

In order to secure sustainable competitiveness of startups, business model innovation is an important task to achieve competitive advantage by transforming the various elements that make up the business model. This study conducted a multi-case analysis study on leading smart farm companies around the world using an analysis framework based on business model theory. Through this, we sought to identify business model types and their constituent elements. For this, 19 companies were selected from the list of top 10 investment startups of the year for the past three years published by Agfunder, a global investment research company specializing in AgTech. Then data collection and analysis of the company cases were conducted according to the case study protocol. As a result of the study, the business model types were analyzed into four types: large-scale centralized production model, medium-to-large local distributed production model, small-scale hyperlocal modular FaaS model, and small-scale hyperlocal turnkey solution supply model. A comparative analysis was conducted on five business model components for each type, and strategic implications were derived through this. This study is expected to contribute to improving the competitiveness of domestic smart farm startups and diversifying their strategies by identifying the business models of overseas leading companies in the smart farm field using an academic analysis framework.

• Journal of the Korea Institute of Information and Communication Engineering
• /
• v.19 no.1
• /
• pp.185-191
• /
• 2015

This paper suggest the safety class communication board in order to design the safety network of the nuclear safety class controller. The reactor protection system use the digitized networks because from analog system to digital system. The communication board shall be provided to pass the required performance and test of the safety class in the digital network used in the nuclear safety class. Communication protocol is composed of physical layer(PHY), data link layer(MAC: Medium Access Control), the application layer in the OSI 7 layer only. The data link layer data package for the cyber security has changed. CRC32 were used for data quality and the using one way communication, not requests and not responses for receiving data, does not affect the nuclear safety system. It has been designed in accordance with requirements, design, verification and procedure for the approving the nuclear safety class. For hardware verification such as electromagnetic test, aging test, inspection, burn-in test, seismic test and environmental test in was performed. FPGA firmware to verify compliance with the life-cycle of IEEE 1074 was performed by the component testing and integration testing.

• Journal of Digital Convergence
• /
• v.21 no.3
• /
• pp.1-14
• /
• 2023

This raises the question of how competitive advantage can be created, prompting firms to enhance their capacity for change. In this context, the role of knowledge creation becomes increasingly vital. This research aims to explore the role of intellectual capital and how to improve knowledge cration ability through absorptive capacity framework. It examines the links among knowledge acquisition, learning of new knowledge, knowledge creation, intellectual capital, and competitive advantage, drawing from both internal and external sources. The study focuses on small and medium-sized supplier firms in Korea, with data collected from 15 industries, totaling 106 responses. The research model employs structural equation modeling (SEM) and utilizes AMOS 22 for analysis. As anticipated, all hypotheses were supported. The study provides robust evidence that absorptive capacity is a pivotal factor in cultivating suppliers' competitive advantage. Furthermore, it posits that intellectual capital should be viewed as a criucial component of suppliers' knowledge stock, significantly enhancing the impact of absorptive capacity on their competitive edge. Future studies should aim to validate the research model in different international settings or across multinational corporations to enhance its generalizabulity.

• Horticultural Science & Technology
• /
• v.31 no.5
• /
• pp.590-597
• /
• 2013

Principle component and emission localization of volatile compounds were investigated according to scent intensity of rose flower. Scent intensity in cultivars and bred-line of Rosa hybrida was divided into three levels; light ('Feel Lip', 'Venus Berry'), medium ('GR07-135'), strong ('Honey Blue'). The major volatile compounds were different depending on the cultivars and selected line; 3,5-dimethoxytoluene (DMT), benzene, 1,3,5-trimethoxy ('Feel Lip'), megastigma-4,6(Z),8(E)-triene ('Venus Berry'), DMT, benzene,1-ethenyl-4-methoxyand, phenylethylalcohol ('GR07-135') and germacrene-D, DMT ('Honey Blue'). The adaxial epidermal cells were conical papillate shape, whereas the abaxial epidermal cells were flat shape. The adaxial epidermal cells of 3 cultivars and 1 selected line were surrounded by thick cell wall and covered by waxy cuticle of 2 cultivars and 1 selected line (except 'Honey Blue'). The adaxial epidermal cells contained starches in 'Feel Lip', osmiophlic droplets in 'Venus Berry', starchs, plastids, vacuoles in 'GR07-135' and plastoglobules, plastids, vacuoles in 'Honey Blue'. Based on these results, it appears that plastids and vacuoles in adaxial epidermal cells with conical papillate shape are associated production and emission of volatile compounds in scent R. hybrida.

• Transactions of the Korean Society of Mechanical Engineers A
• /
• v.35 no.11
• /
• pp.1499-1506
• /
• 2011

The IHX (intermediate heat exchanger) is a key component of nuclear hydrogen systems for the production of massive amounts hydrogen. The IHX transfers the $950^{\circ}C$ heat generated by the VHTR (very high temperature reactor) to a hydrogen production plant. The Korea Atomic Energy Research Institute established a small-scale gas loop to test the performance of key VHTR components and manufactured a small-scale PCHE (printed circuit heat exchanger) prototype, which is being considered as a candidate for the IHX, for testing in the small-scale gas loop. In this study, as a part of the high-temperature structural integrity evaluation of the small-scale PCHE prototype, we carried out high-temperature structural analysis modeling and macroscopic thermal and structural analysis for the small-scale PCHE prototype under the small-scale gas loop test conditions. This analysis serves as a precedent study to scheduled PCHE performance test in the small-scale gas loop. The results obtained in this study will be compared with the test results for the small-scale PCHE and then used to design the medium-scale PCHE prototype.