• Title/Summary/Keyword: Component development

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Anastral Spindle 3/Rotatin Stabilizes Sol narae and Promotes Cell Survival in Drosophila melanogaster

  • Cho, Dong-Gyu;Lee, Sang-Soo;Cho, Kyung-Ok
    • Molecules and Cells
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    • v.44 no.1
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    • pp.13-25
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    • 2021
  • Apoptosis and compensatory proliferation, two intertwined cellular processes essential for both development and adult homeostasis, are often initiated by the mis-regulation of centrosomal proteins, damaged DNA, and defects in mitosis. Fly Anastral spindle 3 (Ana3) is a member of the pericentriolar matrix proteins and known as a key component of centriolar cohesion and basal body formation. We report here that ana3m19 is a suppressor of lethality induced by the overexpression of Sol narae (Sona), a metalloprotease in a disintegrin and metalloprotease with thrombospondin motif (ADAMTS) family. ana3m19 has a nonsense mutation that truncates the highly conserved carboxyl terminal region containing multiple Armadillo repeats. Lethality induced by Sona overexpression was completely rescued by knockdown of Ana3, and the small and malformed wing and hinge phenotype induced by the knockdown of Ana3 was also normalized by Sona overexpression, establishing a mutually positive genetic interaction between ana3 and sona. p35 inhibited apoptosis and rescued the small wing and hinge phenotype induced by knockdown of ana3. Furthermore, overexpression of Ana3 increased the survival rate of irradiated flies and reduced the number of dying cells, demonstrating that Ana3 actively promotes cell survival. Knockdown of Ana3 decreased the levels of both intra- and extracellular Sona in wing discs, while overexpression of Ana3 in S2 cells dramatically increased the levels of both cytoplasmic and exosomal Sona due to the stabilization of Sona in the lysosomal degradation pathway. We propose that one of the main functions of Ana3 is to stabilize Sona for cell survival and proliferation.

Short-circuit Protection Circuit Design for SiC MOSFET Using Current Sensing Circuit Based on Rogowski Coil (Rogowski Coil 기반의 전류 센싱 회로를 적용한 SiC MOSFET 단락 보호 회로 설계)

  • Lee, Ju-A;Byun, Jongeun;Ann, Sangjoon;Son, Won-Jin;Lee, Byoung-Kuk
    • The Transactions of the Korean Institute of Power Electronics
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    • v.26 no.3
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    • pp.214-221
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    • 2021
  • SiC MOSFETs require a faster and more reliable short-circuit protection circuit than conventional methods due to narrow short-circuit withstand times. Therefore, this research proposes a short-circuit protection circuit using a current-sensing circuit based on Rogowski coil. The method of designing the current-sensing circuit, which is a component of the proposed circuit, is presented first. The integrator and input/output filter that compose the current-sensing circuit are designed to have a wide bandwidth for accurately measuring short-circuit currents with high di/dt. The precision of the designed sensing circuit is verified on a double pulse test (DPT). In addition, the sensing accuracy according to the bandwidth of the filters and the number of turns of the Rogowski coil is analyzed. Next, the entire short-circuit protection circuit with the current-sensing circuit is designed in consideration of the fast short-circuit shutdown time. To verify the performance of this circuit, a short-circuit test is conducted for two cases of short-circuit conditions that can occur in the half-bridge structure. Finally, the short-circuit shutdown time is measured to confirm the suitability of the proposed protection circuit for the SiC MOSFET short-circuit protection.

Research on Competitiveness of Information and Telecommunication Industry Using Standard Patent: Focusing on trend and network analysis (표준특허를 활용한 정보통신산업 분야 경쟁력 분석: 트랜드 및 네트워크 분석을 중심으로)

  • Jeong, Myoung Sun
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.22 no.6
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    • pp.534-541
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    • 2021
  • This study aims to establish an efficient future technology development strategy in the information and telecommunications industry by grasping related technology trends and fusion complexity through an analysis based on standard patents. Analyzing 1,983 patents related to the information and telecommunications industry identified the trends in major patent applicants and detailed technologies in the world. In addition, technology trends were investigated through keyword analysis to examine the degree of complexity in information and communications technology, confirming the direction of research in information technology. Electronic component and wireless communications fields have relatively few standard patents, but they are highly convergent with other industrial technologies. Computer information processes and communication and broadcasting technologies are highly related to each other, so they can be used as standard fusion technologies in standard patents. In addition, standardization activities in optical and image/sound devices are found to be high.

Development of Multiplier Operator for Input Signal Control of Electronic Circuits (전자회로의 입력신호 제어용 곱셈연산기 개발)

  • Kim, Jong-Ho;Chang, Hong-Ki;Kwon, Dae-Shik;Che, Gyu-Shik
    • Journal of Advanced Navigation Technology
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    • v.22 no.2
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    • pp.154-162
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    • 2018
  • The multiplier circuit is necessary to estimate degradation status of electronic cards in nuclear power plant, but its accuracy is not easy in processing those functions to multiply two input signals. What is important in multiplier circuit is that the multiplication result must be accurate and its linearity must be perfect. We developed and proposed excellent linearity multiplier circuit using operational amplifiers and transistor characteristics, and then proved its validity in this paper. We have made efforts to eliminate nonlinearity components of semiconductors with this circuit in order to ensure excellent linearity of developed multiplier circuit. We conducted multiplication operations through simulation, applying adequate values to each component in order to verify the circuit composed of that method. We showed step-by-step output signals, and then compared the logical analyses and measuring results as simulation results. We confirmed that this method is superior to existing multiplication or linearity.

Quality Properties of Makgeolli Brewed with Korean Sweet Potato Cultivars (Ipomoea batatas (L.) Lam) (한국 고구마 품종을 발효하여 만든 막걸리의 품질 특성)

  • Yoon, Hyang-Sik;Kang, Hye Jeong;Eom, Hyun-Ju;Jeong, Heon Sang;Chung, Mi-Nam;Kim, In Jae;Kim, Youngho
    • The Korean Journal of Food And Nutrition
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    • v.33 no.6
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    • pp.624-630
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    • 2020
  • This study examined the quality characteristics of Makgeolli to investigate the availability of Korean sweet potato cultivars as alcoholic beverages. The following sweet potato varieties were used: Gogunmi, Daeyumi, Shingunmi, Shinyulmi, Shincheonmi, Jinyulmi, Jinhongmi, Jeungmi and Pungwonmi; their alcohol contents ranged from 12.20% to 14.20%, with the lowest value in Makgeolli made with Jeungmi and the highest value in Makgeolli made with Jinhongmi. The DPPH radical scavenging activity was in the range of 37.51~77.02%, with the lowest value in Makgeolli made with rice (control) and the highest value in Makgeolli made with Gogunmi. As a result of analyzing the aroma component of sweet potato Makgeolli, 27 kinds of aroma components were detected, and six kinds of alcohols, 13 kinds of esters, four kinds of acids, and four kinds of other compounds were found. Regarding the number of aroma compounds, Makgeolli made with Shinyulmi showed the lowest number with 14 kinds, while Makgeolli made with Pungwonmi showed the highest number with 27 kinds.

Robust Design for Parts of Induction Bolt Heating System (유도가열시스템의 구성부품에 대한 강건설계)

  • Kim, Doo Hyun;Kim, Sung Chul;Lee, Jong Ho;Kang, Moon Soo;Jeong, Cheon Kee
    • Journal of the Korean Society of Safety
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    • v.36 no.2
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    • pp.10-17
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    • 2021
  • This paper presents the robust design of each component used in the development of an induction bolt heating system for dismantling the high-temperature high-pressure casing heating bolts of turbines in power plants. The induction bolt heating system comprises seven assemblies, namely AC breaker, AC filter, inverter, transformer, work coil, cable, and CT/PT. For each of these assemblies, the various failure modes are identified by the failure mode and effects analysis (FMEA) method, and the causes and effects of these failure modes are presented. In addition, the risk priority numbers are deduced for the individual parts. To ensure robust design, the insulated-gate bipolar transistor (IGBT), switched-mode power supply (SMPS), C/T (adjusting current), capacitor, and coupling are selected. The IGBT is changed to a field-effect transistor (FET) to enhance the voltage applied to the induction heating system, and a dual-safety device is added to the SMPS. For C/T (adjusting current), the turns ratio is adjusted to ensure an appropriate amount of induced current. The capacitor is replaced by a product with heat resistance and durability; further, coupling with a water-resistant structure is improved such that the connecting parts are not easily destroyed. The ground connection is chosen for management priority.

Classes in Object-Oriented Modeling (UML): Further Understanding and Abstraction

  • Al-Fedaghi, Sabah
    • International Journal of Computer Science & Network Security
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    • v.21 no.5
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    • pp.139-150
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    • 2021
  • Object orientation has become the predominant paradigm for conceptual modeling (e.g., UML), where the notions of class and object form the primitive building blocks of thought. Classes act as templates for objects that have attributes and methods (actions). The modeled systems are not even necessarily software systems: They can be human and artificial systems of many different kinds (e.g., teaching and learning systems). The UML class diagram is described as a central component of model-driven software development. It is the most common diagram in object-oriented models and used to model the static design view of a system. Objects both carry data and execute actions. According to some authorities in modeling, a certain degree of difficulty exists in understanding the semantics of these notions in UML class diagrams. Some researchers claim class diagrams have limited use for conceptual analysis and that they are best used for logical design. Performing conceptual analysis should not concern the ways facts are grouped into structures. Whether a fact will end up in the design as an attribute is not a conceptual issue. UML leads to drilling down into physical design details (e.g., private/public attributes, encapsulated operations, and navigating direction of an association). This paper is a venture to further the understanding of object-orientated concepts as exemplified in UML with the aim of developing a broad comprehension of conceptual modeling fundamentals. Thinging machine (TM) modeling is a new modeling language employed in such an undertaking. TM modeling interlaces structure (components) and actionality where actions infiltrate the attributes as much as the classes. Although space limitations affect some aspects of the class diagram, the concluding assessment of this study reveals the class description is a kind of shorthand for a richer sematic TM construct.

A Study on the Visualization Method for Figurative Art of Sculptures Using Metallic Materials - Based on the purpose of displaying in the residential complex (금속재료를 활용한 조형물의 비유적 이미지 시각화 방법 연구 - 주거 단지 전시를 목적으로)

  • Ko, Seung-Geun
    • Journal of the Korea Convergence Society
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    • v.12 no.1
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    • pp.225-230
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    • 2021
  • As the quality of our life has improved, residential complexes have become more diverse now. Modern residential complexes function as a place for meeting and communication between families and neighbors, including parks, lakes, and promenades, and exhibiting sculptures in residential spaces has become an important component. This study was conducted for the purpose of researching the design development method for the sculptures displayed in the residential space in accordance with these changes and demands of the era. Through the process of visualizing the figurative arts with metal and stone used as materials, the artist's thoughts and messages were put in the sculpture and the arts were completed as the shape of the sculpture that viewers could sympathize with. This design and formative research shows the possibility that various visual elements for sympathy with the creator's thoughts can be formed in a place with the specificity of living space by using a figurative visualization method. Therefore, further researches on figurative art of sculptures are required.

Switching Filter for Preserving Edge Components in Random Impulse Noise Environments (랜덤 임펄스 잡음 환경에서 에지 성분을 보존하기 위한 스위칭 필터)

  • Cheon, Bong-Won;Kim, Nam-Ho
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.24 no.6
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    • pp.722-728
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    • 2020
  • Digital image processing has been applied in a wide range of fields due to the development of IoT technology and plays an important role in data processing. Various techniques have been proposed to remove such noise, but the conventional impulse noise canceling methods are insufficient to remove noise of edge components of an image, and have a disadvantage of being greatly affected by random impulse noise. Therefore, in this paper, we propose an algorithm that effectively removes edge component noise in random impulse noise environment. The proposed algorithm calculates the threshold value by determining the noise level and switches the filtering process by comparing the reference value with the input pixel value. The proposed algorithm shows good performance in the existing method, and the simulation results show that the noise is effectively removed from the edge of the image.

Development of X-Ray Array Detector Signal Processing System (X-Ray 어레이 검출 모듈 신호처리 시스템 개발)

  • Lim, Ik-Chan;Park, Jong-Won;Kim, Young-Kil;Sung, So-Young
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.23 no.10
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    • pp.1298-1304
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    • 2019
  • Since the 9·11 terror attack in 2001, the Maritime Logistics Security System has been strengthened and required X-ray image for every imported cargos from manufacturing countries to United States. For scanning cargos, the container inspection systems use high energy X-rays for examination of contents of a container to check the nuclear, explosive, dangerous and illegal materials. Nowadays, the X-ray cargo scanners are established and used by global technologies for inspection of suspected cargos in the customs agency but these technologies have not been localized and developed sufficiently. In this paper, we propose the X-ray array detector system which is a core component of the container scanning system. For implementation of X-ray array detector, the analog and digital signal processing units are fabricated with integrated hardware, FPGA logics and GUI software for real-time X-ray images. The implemented system is superior in terms of resolution and power consumption compared to the existing products currently used in ports.