• Title/Summary/Keyword: Component States

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The Solvent Effect on The Chemical Changes in Binary Mixture : i. e. THF-$H_2O$ System (Ⅱ) (이성분 혼합용매에서 화학변화에 미치는 용매의 영향 : THF-$H_2O$ (제2보). 매체의 특성과 용매화된 전자의 흡수스펙트럼)

  • Yu-Chul Park;Sang-Oh Oh
    • Journal of the Korean Chemical Society
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    • v.24 no.6
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    • pp.444-451
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    • 1980
  • In order to further elucidate the process of electron solvation in liquids, the medium effect, as the difference between the free energy of $H^+$ in aqueous and non-aqueous states (${\Delta}{\Delta}G_0$), of THF-water mixtures has been investigated. (${\Delta}{\Delta}G_0$) were determined by electromotive force masurements of the cell Pt$H_2Q$, Q, HCI, THF, $H_2O$|KC1 | $Hg_2Cl_2$|Hg(Pt), where $H_2Q$ and Q are hydroquinone and quinone respectively. The effect of dielectric constant on the difference of free energy and the absorption energy of solvated electrons have been studied. For the consideration of these effect the polymerization of water in THF has been studied. Near infrared spectrum of O-H stetching energy has been used to measure the extent of water aggregates. The expermental results indicate that at least in some composition of binary mixtures the electrons or other ions are solvated preferentially with one component of solvents.

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Study on Volterra System for Variation of Metacentric Height in Waves and its Application to Analysis of Parametric Roll (볼테라 시스템을 이용한 파랑 중 파라메트릭 횡동요에 대한 연구)

  • Lee, Jae-Hoon;Kim, Yonghwan
    • Journal of the Society of Naval Architects of Korea
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    • v.54 no.3
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    • pp.227-241
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    • 2017
  • In this study, a Volterra system for the variations of metacentric height (GM) in waves is employed to simulate the parametric roll phenomena of ships in head sea condition. Using the present Volterra system, the transfer function of each harmonic component in the GM variation is computed for different ship models, including mathematical models and a real containership, and the results are validated through the comparison with the values obtained using the direct calculations based on a weakly nonlinear time-domain method. Then, a semi-analytic approach employing a 1-degree of freedom equation for roll motion is developed to simulate the parametric roll motions in irregular waves. In the derived approach, the nonlinear and time-varying restoring forces in the waves are approximated using the Volterra system. Through simulations of the parametric roll for different sea states, the effects of the 1st and 2nd-order harmonic components of the variations in the occurrence and amplitude of the parametric roll motions are investigated. Because of the strong nonlinearities in the phenomena, a stochastic analysis is conducted to examine the statistical properties of the roll motions in consideration of the sensitivities and uncertainties in the computations.

Stabilization of Dry Immuno-Diagnostic Kit with Immobilized Antibody and Determination of Its Shelf-Life (항체가 건조상태로 고정된 면역진단키트의 안정화와 Shelf-Life 결정)

  • 이창우;조정환;육순학;권오협;박영남;박세환
    • KSBB Journal
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    • v.13 no.5
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    • pp.502-510
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    • 1998
  • Stabilization of antibody, which is specific to Salmonella typhimurium antigens, present in dry states on membranes was accomplished, and its shelf-life, i.e., duration for maintaining minimum 90% of the initial activity, under optimal conditions was determined. To prepare two major components of an immuno-strip, the antibody was not only immobilized on nitrocellulose membrane surfaces but also placed within the pores of glass fiber membrane after conjugating it with old colloids as signal generator. Among potential stabilizers of the immuno-components, a disaccharide, trehalose, showed a significant protection effect of immunoglobulin structure from thermal energy. Optimal concentrations of trehalose for the respective component were significantly different (8-fold higher for the antibody-gold conjugate than for the immobilized antibody), which probably resulted from distinct densities and configurations of antibody present on the membranes. An additional requirement for the gold conjugate was freeze-drying of this substance such that the conjugate can be readily resolubilized upon contact with aqueous medium. By using the components prepared under optimal conditions, immuno-strips were constructed and exposed to thermal energy. Signals with less than 10% decrease in the intensity were maintained for approximately 21 days at 60$^{\circ}C$. Compared to previous reports, this result represented a 2-year shelf-life at room temperature. it was, however, two times longer if determined from thermal acceleration tests based on the theory of inactivation rate of protein. Such discrepancy between the two estimates could be mainly attributed to errors in accurately controlling temperatures and also to changes in the physical properties of membranes due to a high thermal energy.

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Plasticity Model Using Three Orthogonal Stress Components for Concrete in Compression (압축력을 받는 콘크리트에 대한 세 직교 응력 성분을 이용한 소성 모델)

  • Kim Jae-Yo;Park Hong-Gun
    • Journal of the Korea Concrete Institute
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    • v.16 no.3 s.81
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    • pp.345-356
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    • 2004
  • A plasticity model was developed to predict the behavioral characteristics of concrete in multiaxial compression. To extend the applicability of the proposed model to concrete in various stress states, a new approach for failure criteria was attempted. A stress was decomposed into one volumetric and two deviatoric components orthogonal to each other. Three failure criteria wire provided independently for each stress component. To satisfy the three failure criteria, the plasticity model using multiple failure criteria was Implemented. Each failure surface was defined by equivalent volumetric or deviatoric plastic strain. To present dilatancy due to compressive damage a non-associative flow nile was proposed. The proposed model was implemented to finite element analysis, and it was verified by comparisons with various existing test results. The comparisons show that the proposed model predicted well most of the experiments by using three independent failure criteria.

A Study on Morphological and Pattern Analysis in 2 kinds of Paeoniae Radix (2종(種) 작약류(芍藥類)의 내외부형태(內外部形態)와 패턴분석 연구(硏究))

  • Song, Kyoung-Song;Choi, Go-Ya;Kim, Hong-Jun;Ju, Young-Sung
    • Korean Journal of Oriental Medicine
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    • v.11 no.2
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    • pp.141-154
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    • 2005
  • The following is a taxonomic list of the specific features of external and internal shape and pattern analysis of Paeonia lactiflora PALL. and P. obovata MAX as the standard of herbal medicine. 1. External shape of original plant P. lactiflora has lancelate and elliptical leaves with no hair on both sides. It bears a flower bud at the shoot apex or leaf axil. On the other hand, P. obovata has obovate leaves with hair on the back side. It has a single flower bud at the shoot apex. 2. Physical characteristics of herbal states P. lactiflora has a bright and smooth external surface whose color is light red brown, light gray on its section and it is not easy to cut. On the other hand, P. obovata has a coarse external surface whose color is dark brown, pinkish on its section and it is easy to cut. 3. Physical characteristics of herbal state in currents Paeonia Radix Alba is brown on the external surface, and whitish on its section. On the other hand, Paeonia Radix Rubra is dark brown on the external surface, and yellowish-white on its section. 4. Internal characteristics Internal shape is correspond to that of Paeonia Radix described in literatures. Only P. lactoflora has a concentrated vascular bundle toward centeral cylinder. On the other hand, P. obovata has a scattered vascular bundle at the cortex. 5. Physicochemical pattern by HPLC Both P. lactoflora and P. obovata showed the same pattern. Paeoniforin, a main component, appears upon 13.68 in retention time (Rt) in both. In addition, both contain a large amount of paeoniflorin. Such results will, in the future, be used as basic source for the additional research, such as biological reactions and genetic discrimination.

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THE COMBINATION OF CHEMOMETRICS AND 2D NIR CORRELATION SPECTROSCOPY IN THE ANALYSIS OF DENATURATION PROCESS

  • Czarnik-Matusewicz, Boguslawa;Murayama, Koichi;Wu, Yuqing;Ozaki, Yukihiro
    • Proceedings of the Korean Society of Near Infrared Spectroscopy Conference
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    • 2001.06a
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    • pp.1286-1286
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    • 2001
  • Despite extensive theoretical and experimental studies the structure of the protein-solvent interface is subject of many controversy. Understanding the processes that occur in aqueous solution requires understanding of the solvent influence on the structure of protein. The aim of this study is to investigate the applicability of NIR methods in the study of hydration phenomena in protein solutions. Temperature-induced changes in NIR spectra of -lactoglobulin (BLG) in aqueous solutions have been investigated by means of two-dimensional correlation spectroscopy (2DCOS) and principal component analysis (PCA). With the temperature increase the balance of forces between the BLG's interaction with itself and the BLGs interaction with its environment is disrupted leading to BLG unfolding. Significant differences of 2D signals and distinct discrepancies of loading on PC1 and PC2 were observed as a result of temperature increase. In the native folded conformation of BLC, most of the nonpolar amino acids are hidden in the centre of the structure, out of contact with water molecules, while charged groups are outside, in the contact with water. The polar groups promote low density Ih-type structure in the water outside this first hydration shell. When BLG unfolds it assumes a more extended configuration on which the previously buried nonpolar groups are exposed to water and promote the higher density II-type structure outside its first shell. Detailed assignments of bands attributed to the bulk water, different states of the hydrated water and the changed conformation of BLG are proposed.

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Decision-making of alternative pylon shapes of a benchmark cable-stayed bridge using seismic risk assessment

  • Akhoondzade-Noghabi, Vahid;Bargi, Khosrow
    • Earthquakes and Structures
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    • v.11 no.4
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    • pp.583-607
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    • 2016
  • One of the main applications of seismic risk assessment is that an specific design could be selected for a bridge from different alternatives by considering damage losses alongside primary construction costs. Therefore, in this paper, the focus is on selecting the shape of pylon, which is a changeable component in the design of a cable-stayed bridge, as a double criterion decision-making problem. Different shapes of pylons include H, A, Y, and diamond shape, and the two criterion are construction costs and probable earthquake losses. In this research, decision-making is performed by using developed seismic risk assessment process as a powerful method. Considering the existing uncertainties in seismic risk assessment process, the combined incremental dynamic analysis (IDA) and uniform design (UD) based fragility assessment method is proposed, in which the UD method is utilized to provide the logical capacity models of the structure, and the IDA method is employed to give the probabilistic seismic demand model of structure. Using the aforementioned models and by defining damage states, the fragility curves of the bridge system are obtained for the different pylon shapes usage. Finally, by combining the fragility curves with damage losses and implementing the proposed cost-loss-benefit (CLB) method, the seismic risk assessment process is developed with financial-comparative approach. Thus, the optimal shape of the pylon can be determined using double criterion decision-making. The final results of decision-making study indicate that the optimal pylon shapes for the studied span of cable-stayed bridge are, respectively, H shape, diamond shape, Y shape, and A shape.

Study of Skin Elasticity and Wrinkle Properties of Elderly Female according to Sasang Constitution-based Health State (고령자 여성의 체질건강수준에 따른 피부 탄성 및 주름 특성 연구)

  • Kim, Young-Min;Jung, Chang-Jin;Ku, Bon-Cho;Jeon, Young-Ju;Kim, Keun-Ho;Kim, Jong-Yeol;Kim, Jaeuk U.
    • Korean Journal of Oriental Medicine
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    • v.18 no.3
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    • pp.119-126
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    • 2012
  • 1. Objectives Sasang constitutional medicine is unique in Korean traditional medicine. It diagnoses and treats patients based on his/her Sasang constitution (SC). Skin properties have been used as an effective diagnostic component in the classification of SC types in clinics. In this paper, we investigated the SC-based health relevance of skin elasticity and wrinkle properties. 2. Methods The skin elasticity and wrinkle of forearm and dorsal hand were measured in 299 elderly female subjects. To determine the subject's Sasang constitution, we adopted the classification results from a newly developed SC diagnostic tool. The health states of the subjects were scored by two Korean traditional medical doctors, by whom each subject was categorized either into the healthy state or the unhealthy state. 3. Results As a result, the elasticity hysteresis of forearm (E_HYS), the visco-elasticity (VE_MEAN), and the wrinkle frequency energy of backhand (W_HAND) showed significant differences between Taeum-in group and Soeum-in group. In case of the Soeum-in on unhealthy state, VE_MEAN was decreased significantly (p<.05). W_HAND and W_ARM_H of the healthy Taeum-in were less than those of the unhealthy Taem-in. 4. Conclusions In this study we showed that, for an elderly female population, skin elasticity and viscosity were significantly different not only between each SC type but also between healthy group and unhealthy group in each constitution. In particular, Soeum-in subjects were inferred to be superior in retaining skin softness when they were healthy, and Taeum-in subjects were easy to lose their firmness of skin surface when they became unhealthy.

Cancer Registration in India - Current Scenario and Future Perspectives

  • Chatterjee, Sharmila;Chattopadhyay, Amit;Senapati, Surendra Nath;Samanta, Dipti Rani;Elliott, Leslie;Loomis, Dana;Mery, Lesly;Panigrahi, Pinaki
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.8
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    • pp.3687-3696
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    • 2016
  • Cancer registration, an important component of cancer surveillance, is essential to a unified, scientific and public health approach to cancer prevention and control. India has one of the highest cancer incidence and mortality rates in the world. A good surveillance system in the form of cancer registries is important for planning and evaluating cancer-control activities. Cancer registration in India was initiated in 1964 and expanded since 1982, through initiation of the National Cancer Registry Program (NCRP) by the Indian Council of Medical Research. NCRP currently has twenty-six population based registries and seven hospital based registries. Yet, Indian cancer registries, mostly in urban areas, cover less than 15% of the population. Other potential concerns about some Indian registries include accuracy and detail of information on cancer diagnosis, and timeliness in updating the registry databases. It is also important that necessary data collection related quality assurance measures be undertaken rigorously by the registries to ensure reliable and valid information availability. This paper reviews the current status of cancer registration in India and discusses some of the important pitfalls and issues related to cancer registration. Cancer registration in India should be complemented with a nationwide effort to foster systematic investigations of cancer patterns and trends by states, regions and sub populations and allow a continuous cycle of measurement, communication and action.

Influence of the Social Support on their Mental Health of the Rheumatoid Arthritis Patients (만성 관절염 환자의 사회적 지지가 우울, 자아존중감에 미치는 영향)

  • Lee, Sun-Ock
    • The Journal of Korean Academic Society of Nursing Education
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    • v.9 no.2
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    • pp.253-263
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    • 2003
  • Rheumatoid arthritis patients not only suffer from the physical damage, but they are afflicted severely mental and psychologic after effects. Their depression and low self-esteem eventually yields serious mental damages, which makes difficult for them to recover. The states of mental health of arthritis patients are diversified depending on the characters and surrounding circumstances, although they may have suffered from the similar condition. Therefore this research was conbucted to the factors that can give positive influences to the patients. In recent time, social support for the arthritis patients has become an important factor that can positively influence their mental health. In other words, social support can act as an important environmental system for arthritis patients to recover their damaged mental health. In order to fulfill this purpose, 118 patients were examined to identify the relationship between the variables. The summary of the result obtained from the research is as follow: 1. The structural aspect of social support for arthritis patients showed the most of them had various social support network size and their highest support system were 'family', 'relative' and 'friends'. The functional aspect of social support for arthritis patients showed moderate degree and their highest sub component was 'approval'. 2. High correlation was found between duration of relationship, similarity, frequency of meeting and functional support. There was no relationship between depression, self-esteem and social support. 3. Therefore this research has suggested that nurses who care rheumatoid arthritis patient consider the above condition to develop self-help group.

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