• 한국가스학회지
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• 제5권2호
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• pp.52-61
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• 2001

[ $100,000m^3$ ] 규모의 원통형 탱크에 저장되어 있는 초저온의 액화천연가스는 외부조건 및 운전모드에 따라 복잡한 유동양상과 열물성 변화를 보인다. 이런 현상은 LNG의 저장 및 운전조건과 탱크의 설계사양 및 열전달 특성에 크게 영향을 받으며, 또한 저장탱크내 LNG의 안정적 저장 및 공급에 영향을 미치게 된다. 따라서, 본 연구에서는 LNG 저장탱크의 외부조건에 따른 2차원 열전달 해석, 시운전시 초기 상온상태의 LNG 저장탱크를 냉각하기 위한 Cool Down 프로세스, 그리고 탱크내 LNG의 유입 및 상승을 고려한 주입프로 세스의 해석을 수행하였다. 또한, 혼합 LNG 저장에 대한 해석도 수행하였다. 이런 LNG저장탱크내의 전반적인 열유동에 대한 해석을 토대로 가시화된 종합적인 열유동 해석프로그램을 개발하였다. 본 프로그램의 개발은 탱크내 저장된 LNG의 열적 안정성 해석의 기술력 확보뿐만 아니라 실탱크의 기본설계에 이용할 수 있게 되었다.

• Bulletin of the Korean Chemical Society
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• 제35권3호
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• pp.858-864
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• 2014

Recently, many researches have shown that even photosynthetic light-harvesting pigment-protein complexes can have quantum coherence in their excitonic energy transfer at cryogenic and physiological temperatures. Because the protein supplies such noisy environment around pigments that conventional wisdom expects very short lived quantum coherence, elucidating the mechanism and searching for an applicability of the coherence have become an interesting topic in both experiment and theory. We have previously studied the quantum coherence of a phycocyanin 645 complex in a marine algae harvesting light system, using Poisson mapping bracket equation (PBME). PBME is one of the applicable methods for solving quantum-classical Liouville equation, for following the dynamics of such pigment-protein complexes. However, it may suffer from many defects mostly from mapping quantum degrees of freedom into classical ones. To make improvements against such defects, benchmarking targets with more accurately described dynamics is highly needed. Here, we fall back to reduced hierarchical equation of motion (HEOM), for such a purpose. Even though HEOM is known to applicable only to simplified system that is coupled to a set of harmonic oscillators, it can provide ultimate accuracy within the regime of quantum-classical description, thus providing perfect benchmark targets for certain systems. We compare the evolution of the density matrix of pigment excited states by HEOM against the PBME results at physiological temperature, and observe more sophisticated changes of density matrix elements from HEOM. In PBME, the population of states with intermediate energies display only monotonically increasing behaviors. Most importantly, PBME suffers a serious issue of wrong population in the long time limit, likely generated by the zero-point energy leaking problem. Future prospects for developments are briefly discussed as a concluding remark.

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 1991년도 한국자동제어학술회의논문집(국제학술편); KOEX, Seoul; 22-24 Oct. 1991
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• pp.1627-1632
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• 1991

A compact type LDPE autoclave reactor is analyzed with respect to the effects of the initiator feed concentration and the rate of heat transfer by employing the mixing-cell model with backflow. Singularity theory is applied for the single-cell model so that one can construct all the possible bifurcation diagrams. Since the single-cell model may not be adequate for the actual reactor, a two-cell model is also treated to predict the dynamic behavior of the reactor. As the rate of heat transfer increases, various multiplicity patterns and oscillatory motions are found. Apparently, the monomer conversion can be substantially increased with proper he-at removal and initiator supplement scheme. For this, however, the complex dynamic features accompanied must be taken into consideration in the reactor design.

• 한국철도학회:학술대회논문집
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• 한국철도학회 2008년도 추계학술대회 논문집
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• pp.1807-1820
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• 2008

The station area development planed to improve the old and narrowed station and to enhance the train passenger's convenience through private capital attraction in the past. But it has been faced with difficulty for the creative of transfer demand. Because of lean upon building facilities were caused by shortage of business profitability as to development of the upside a railway line, and lack of public utilities. The station area development requires that it's trend to large scale development of station areas, korail's direct development, deputation of specialty company to development, collaboration between local government and korail in development, diversification of process & installed facility, building multi-transfer center and one-stop transfer system. This trend caused by low profitability in development of the upside a railway line. The purposes of study are to make the system and law reflected to the property of station area development, investment in kind of needed land, and change railroad areas to high-rise and complex development, and make a forum between government and korail, etc.

• Rapid Communication in Photoscience
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• 제4권2호
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• pp.37-40
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• 2015

To examine the photosensitized biomolecules damaging activity, dimethoxyP(V)tetrakis(2-naphthyl)porphyrin (NP) and dimethoxyP(V)tetraphenylporphyrin (PP) were synthesized. The naphthyl moiety of NP hardly deactivated the photoexcited P(V)porphyrin ring in ethanol. In aqueous solution, the naphthyl moiety showed the quenching effect on the photoexcited porphyrin ring, possibly through electron transfer and self-quenching by a molecular association. Binding interaction between human serum albumin (HSA), a water soluble protein, and these porphyrins could be confirmed by the absorption spectral change. The apparent association constant of NP was larger than that of PP. It is explained by that more hydrophobic NP can easily bind into the hydrophobic pockets of HSA. The photoexcited PP effectively induced damage of the tryptophan residue of HSA, through electron transfer-mediated oxidation and singlet oxygen generation. NP also induced HSA damage during photo-irradiation and the contributions of the electron transfer and singlet oxygen mechanisms were speculated. The electron transfer-mediated mechanism to the photosensitized protein damage should be advantageous for photodynamic therapy in hypoxic condition. The quantum yield of the HSA photodamage by PP was significantly larger than that of NP. The quenching effect of the naphthyl moiety is considered to suppress the photosensitized protein damage. In conclusion, the naphthalene substitution to the P(V)porphyrins can enhance the binding interaction with hydrophobic biomacromolecules such as protein, however, this substitution may reduce the photodynamic effect of P(V)porphyrin ring in aqueous media.

• 한국생물물리학회:학술대회논문집
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• 한국생물물리학회 2003년도 정기총회 및 학술발표회
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• pp.62-62
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• 2003

The native form of serpin (serine protease inhibitor) is kinetically trapped in metastable state. Metastability in these proteins is critical to their biological function. Serpins inhibit target proteases by forming a stable covalent complex in which the cleaved reactive site loop of the serpin is inserted into $\beta$-sheet A of the serpin with concomitant translocation of the protease to the opposite of the initial binding site. Despite recent determination of the crystal structures of a Michaelis protease-serpin complex as well as a stable covalent complex, details on the kinetic mechanism remain unsolved. In this study we constructed several $\alpha$$_1$-antitrypsin variants and examined their kinetic mechanism of loop translocation and formation of protease-serpin complex by stopped-flow experiments of fluorescence resonance energy transfer as well as quenched-flow experiment. We report here the relationship of serpin's conformational switch mechanism with Inhibitory activity. There is little direct correlation between loop insertion rate and inhibitory activity. Rather, disrupting a salt bridge between R196 and E354 accelerates loop translocation even though it impairs the inhibitory activity. Moreover, the serpin's reactive site loop is translocated, at least partially, prior to loop cleavage.

• Bulletin of the Korean Chemical Society
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• 제21권9호
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• pp.923-928
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• 2000

[FeIII(BBA)DBC]ClO4 as a new functional model for catechol dioxygenases has been synthesized, where BBA is a bis(benzimidazolyl-2-methyl)amine and DBC is a 3,5-di-tert-butylcatecholate dianion.The BBA complex has a structuralfeature that iron cent er has a five-coordinate geometry similar to that of catechol dioxygenase-substrate complex.The BBA complex exhibits strong absorptionbands at 560 and 820 nm in CH3CN which are assigned to catecholate to Fe(III) charge transfer transitions. It also exhibits EPR signals at g = 9.3 and 4.3 which are typical values for the high-spin FeIII (S = 5/2) complex with rhombicsymmetry. Interestingly, the BBA complex reacts with O2 within an hour to afford intradiol cleavage (35%) and extradiol cleavage (60%) products. Surprisingly, a green color intermediate is observed during the oxygenation process of the BBA com-plex in CH3CN. This green intermediate shows a broad isotropic EPR signal at g = 2.0. Based on the variable temperature EPR study, this isotropic signalmight be originated from the [Fe(III)-peroxo-catecholate] species havinglow-spin FeIII center, not from the simple organic radical. Consequently,it allows O2 to bind to iron cen-ter forming the Fe(III)-superoxide species that converts to the Fe(III)-peroxide intermediate. These present data can lead us tosuggest that the oxygen activation mechanism take place for the oxidative cleavingcatechols of the five-coordinate model systems for catechol dioxygenases.

• Structural Engineering and Mechanics
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• 제64권4호
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• pp.473-485
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• 2017

An isolated building, composed of superstructure and isolation system which have very different damping properties, is typically non-classical damping system. This results in inapplicability of traditional response spectrum method for isolated buildings. A multidimensional response spectrum method based on complex mode superposition is herein introduced, which properly takes into account the non-classical damping feature in the structure and a new method is developed to estimate velocity spectra from the commonly used displacement or pseudo-acceleration spectra based on random vibration theory. The error of forced decoupling method, an approximated approach, is discussed in the viewpoint of energy transfer. From the base-isolated benchmark model, as a numerical example, application of the procedure is illustrated companying with comparison study of time-history method, forced decoupling method and the proposed method. The results show that the proposed method is valid, while forced decoupling approach can't reflect the characteristics of isolated buildings and may lead to insecurity of structures.

• 대한기계학회:학술대회논문집
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• 대한기계학회 2003년도 춘계학술대회
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• pp.1453-1460
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• 2003

The present study investigates the effects of rib arrangements and aspect ratios of a rectangular duct simulating the cooling passage of a gas turbine blade. Two different V-shaped rib configurations are tested with the aspect ratios (W/H) of 3 to 6.82. One is the continuous V-shaped rib configuration with $60^{\circ}$ attack angle, and the other is the discrete V-shaped rib configuration with $45^{\circ}$ attack angle. The square ribs with the pitch to height ratio of 10.0 are installed on the test section in a parallel arrangement for both rib configurations. Reynolds numbers based on the hydraulic diameter are changed from 10,000 to 30,000. A naphthalene sublimation method is used to measure local heat/mass transfer coefficients. For the continuous V-shaped rib configuration, two pairs of counter-rotating vortices are generated in a duct, and high transfer region is formed at the center of the ribbed walls of the duct. However, for the discrete V-shaped rib configuration with $45^{\circ}$ attack angle, complex secondary flow patterns are generated in the duct due to its geometric feature, and more uniform heat/mass transfer distributions are obtained for all tested cases

• Biotechnology and Bioprocess Engineering:BBE
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• 제6권4호
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• pp.279-283
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• 2001

Cationic lipid emulsion system consisting of 1, 2-dioleoyl-sn-slycero-3-trimethyl-ammonium-propane(DOTAP) and plasmin DNA with various counterions in the lipid headgroups were prepared. The transfection activity of the cationic lipid emulsion systems was then investigated in vitro and in vivo. The complex formation of plasmid DNA lipid emulsion was affected by the counterions through charged headgroup repulsion and also by the salt concen-tration in the media. As such , the transfection activity of the DOTAP emulsion system can be controlled by changing the counterions.