• Journal of the Korean Society of Propulsion Engineers
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• v.5 no.1
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• pp.18-25
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• 2001

The results of systematic numerical experiments of secondary gas injection thrust vector control are presented. The effects of secondary injection system such as injection location and nozzle divergent cone angle onto the overall performance parameters such as thrust ratio, specific impulse ratio and axial thrust augmentation, are investigated. Complex nozzle exhaust flows induced by the secondary jet penetration is numerically analyzed by solving unsteady three-dimensional Reynolds-averaged Navier-Stokes equations with Baldwin-Lomax turbulence model for closure. Numerical simulations compared with the experiments of secondary air injection into the rocket nozzle of $9.6^{\cire}$ divergent half angle showed good agreement. The results obtained in terms of overall performance parameters showed that locating the secondary injection orifice further downstream of primary nozzle ensures the prevention of occurrence of reflected shock wave, therefore is suitable for efficient and stable thrust vectoring over a wide range of use.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.39A no.5
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• pp.251-257
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• 2014

Digital RDA system is retransmit into the opposite direction of the incident signals. Digital RDA system have a disadventage that this system do not signal classification in multipath environment. because multipath signal is shown as vector sum of multipath signal, digital RDA system required complex signal process for multipath signal classification. In this paper, to solve these problem we propose hybrid digital RDA system which combination of the MUSIC algorithm and the digital RDA system. Proposed system has two modes. First mode is digital RDA mode. Secornd mode is digital beamforming mode. Digital RDA mode is used in situations where the less the impact of multipath. Digital beamforming mode is applied to multipath effects is greater. In secornd mode, we find optimal path using MUSIC algorithm. After than the proposed system uses only the optimal path. Through the proposed system in a multipath environment with digital RDA can be used to supplement a disadvantage.

• Applied Microscopy
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• v.37 no.2
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• pp.123-133
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• 2007

The strain fields due to precipitates, especially S-phase $(Al_2CuMg)$ particles in Al-2.5Cu-1.5Mg wt.% alloy were first investigated with Large Angle Convergent Beam Electron Diffraction (LACBED) method. The work involves LACBED pattern simulations to estimate possibly the strength of the strain fields. To do this the morphology of S-particle was optimized as a cylindrical shape with $a_s$ axis, and the displacement vector of strain fields was assumed to be perpendicular to $a_s$ axis. With this simple model the reasonable fittings between the observed patterns of the strain fields and simulations were obtained. And in the early aging stage of the alloy the significant strain fields were not observed. As a result of this study it is expected that the strain fields due to S-phase precipitates in the stage with maximum hardness would make a complex networks to possibly contribute to hardiness of the alloy.

• Korean Journal of Poultry Science
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• v.42 no.3
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• pp.239-245
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• 2015

Transgenic animals have been widely used for developmental biology studies, as disease models, and even in industry such as transgenic bioreactor animals. For transgenic birds, quail has the great advantages of small body size, short generation time, and frequent egg production. To date, retroviral or lentiviral transduction has been used to generate transgenic quail for various purposes. However, the efficiency of transgenic offspring production with these methods is relatively low and viral vector usage has safety issues. Unfortunately, non-viral transgenesis has not been established in quail due to a deficiency of stem cell and germ cell culture systems. In this study, we established a direct in ovo lipofection method that could be used to create transgenic quail without germline-competent cells or viruses. To optimize the injection stage during embryo development, the liposome complex (containing piggyBacCMV-GFP and transposase plasmids) was introduced into an embryonic blood vessel at 50 hr, 55 hr or 60 hr. GFP expression was detected in various tissues (heart, kidney, liver and stomach) on day 12 of incubation under a fluorescence microscope. Additionally, GFP-positive cells were detected in the recipient embryonic gonads. In conclusion, the direct in ovo lipofection method with the piggyBac transposon could be an efficient and useful tool for generating transgenic quail.

• Journal of the Korea Society of Computer and Information
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• v.26 no.11
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• pp.33-40
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• 2021

Due to advanced complex strategies, the complexity of information that a commander must analyze is increasing. An intelligent service that can analyze battlefield is needed for the commander's timely judgment. This service consists of extracting knowledge from battlefield information, building a knowledge base, and analyzing the battlefield information from the knowledge base. This paper extract information similar to an input query by embedding the knowledge base built in the 2^nd step. The transformation model is needed to generate the embedded knowledge base and uses the random-walk algorithm. The transformed information is embedding using Word2Vec, and Similar information is extracted through cosine similarity. In this paper, 980 sentences are generated from the open knowledge base and embedded as a 100-dimensional vector and it was confirmed that similar entities were extracted through cosine similarity.

• The Journal of the Korea institute of electronic communication sciences
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• v.14 no.2
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• pp.439-446
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• 2019

In this paper, we propose a encryption method using C-MLCA and 1D CAT to secure medical image for efficiently. First, we generate a state transition matrix using a Wolfram rule and create a sequence of maximum length. By operating the complemented vector, it converts an existing sequence to a more complex sequence. Then, we multiply the two sequences by rows and columns to generate C-MLCA basis images of the original image size and go through a XOR operation. Finally, we will get the encrypted image to operate the 1D CAT basis function created by setting the gateway values and the image which is calculated by transform coefficients. By comparing the encrypted image with the original image, we evaluate to analyze the histogram and PSNR. Also, by analyzing NPCR and key space, we confirmed that the proposed encryption method has a high level of stability and security.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.22 no.1
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• pp.786-791
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• 2021

In this paper, in order to minimize limitations such as signal interference and positioning errors in existing indoor positioning systems, a smart LED-based positioning system for excellent line-of-sight radio environments and precise location tracking is proposed to improve accuracy. An IEEE 802.4 Zigbee module is mounted on the SMPS board of a smart LED; RSSI and LQI signals are received from a moving tag, and the system is configured to transmit the measured data to the positioning server through a gateway. For the experiment, the necessary hardware, such as the gateway and the smart LED module, were separately designed, and the experiment was conducted after configuring the system in an external field office. The positioning error was within 70cm as a result of performing complex calculations in the positioning server after transmitting a vector value of the moving object obtained from the direction sensor, together with a signal from the moving object received by the smart LED. The result is a significantly improved positioning error, compared to an existing short-range wireless communications-based system, and shows the level at which commercial products can be implemented.

• Journal of Physiology & Pathology in Korean Medicine
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• v.34 no.4
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• pp.177-183
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• 2020

The Hippo-YAP signaling pathway is critical for cell proliferation, survival, and self-renewal in both Drosophila and mammals. Disorder of Hippo-YAP pathway leads to tumor development, progression and poor prognosis in various cancers. YAP/TAZ are the key downstream effectors of the Hippo pathway and they can be inhibited through LATS1/2, core kinases in the Hippo pathway, mediated phosphorylation. In this study, we investigated the effect of Angelica gigas Nakai extract (AGNE) on Hippo-YAP/TAZ pathway. First, ANGE induced YAP/TAZ phosphorylation and dissociation of the YAP/TAZ-TEAD transcription complex. By qRT-PCR, we found that ANGE inhibits the expression of YAP/TAZ-TEAD target gene, CTGF and CYR61. In addition, the transcriptional activity of YAP/TAZ was not suppressed significantly in LATS1/2 double-knockout (DKO) cells by ANGE compared to LATS1/2 wild-type (WT) cells, which means AGNE inhibits YAP/TAZ signaling through direct action on LATS1/2. Further, it was confirmed that AGNE-induced activation of LATS1/2 inhibited the migration potential of the vector-expressing cells by suppressing YAP/TAZ activity. The reduced migration potential was restored in active YAP-TEAD expressing cells. Taken together, the results of this study indicate that ANGE downregulates YAP/TAZ signaling in cells through the activation of LATS1/2.

• Journal of Microbiology and Biotechnology
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• v.32 no.6
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• pp.749-760
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• 2022

α-Galactosidase is a debranching enzyme widely used in the food, feed, paper, and pharmaceuticals industries and plays an important role in hemicellulose degradation. Here, T26, an aerobic bacterial strain with thermostable α-galactosidase activity, was isolated from laboratory-preserved lignocellulolytic microbial consortium TMC7, and identified as Parageobacillus thermoglucosidasius. The α-galactosidase, called T26GAL and derived from the T26 culture supernatant, exhibited a maximum enzyme activity of 0.4976 IU/ml when cultured at 60℃ and 180 rpm for 2 days. Bioinformatics analysis revealed that the α-galactosidase T26GAL belongs to the GH36 family. Subsequently, the pET-26 vector was used for the heterologous expression of the T26 α-galactosidase gene in Escherichia coli BL21 (DE3). The optimum pH for α-galactosidase T26GAL was determined to be 8.0, while the optimum temperature was 60℃. In addition, T26GAL demonstrated a remarkable thermostability with more than 93% enzyme activity, even at a high temperature of 90℃. Furthermore, Ca²⁺ and Mg²⁺ promoted the activity of T26GAL while Zn²⁺ and Cu²⁺ inhibited it. The substrate specificity studies revealed that T26GAL efficiently degraded raffinose, stachyose, and guar gum, but not locust bean gum. This study thus facilitated the discovery of an effective heat-resistant α-galactosidase with potent industrial application. Meanwhile, as part of our research on lignocellulose degradation by a microbial consortium, the present work provides an important basis for encouraging further investigation into this enzyme complex.

• Proceedings of the Korean Society of Propulsion Engineers Conference
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• 2008.03a
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• pp.790-798
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• 2008

Counter-rotating axial flow fan(CRF) consists of two counter-rotating rotors without stator blades. CRF shows the complex flow characteristics of the three-dimensional, viscous, and unsteady flow fields. For the understanding of the entire core flow in CRF, it is necessary to investigate the three-dimensional unsteady flow field between the rotors. This information is also essential to improve the aerodynamic characteristics and to reduce the aerodynamic noise level and vibration characteristics of the CRF. In this paper, experimental study on the three-dimensional unsteady flow of the CRF is performed at the design point(operating point). Flow fields in the CRF are measured at the cross-sectional planes of the upstream and downstream of each rotor using the $45^{\circ}$ inclined hot-wire. The phase-locked averaged hot-wire technique utilizes the inclined hot-wire, which rotates successively with 120 degree increments about its own axis. Three-dimensional unsteady flow characteristics such as tip vortex, secondary flow and tip leakage flow in the CRF are shown in the form of the axial, radial and tangential velocity vector plot and velocity contour. The phase-locked averaged velocity profiles of the CRF are analyzed by means of the stationary unsteady measurement technique. At the mean radius of the front rotor inlet and the outlet, the phase-locked averaged velocity profiles show more the periodical flow characteristics than those of the hub region. At the tip region of the CRF, the axial velocity is decreased due to the boundary layer effect of the fan casing and the tip vortex flow. The radial and the tangential velocity profiles show the most unstable and unsteady flow characteristics compared with other position of rotors. But, the phase-locked averaged velocity profiles of the downstream of the rear rotor show the aperiodic flow pattern due to the mixture of the front rotor wake period and the rear rotor rotational period.