• 한국추진공학회:학술대회논문집
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• 한국추진공학회 2017년도 제48회 춘계학술대회논문집
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• pp.41-46
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• 2017

한반도를 둘러싼 세 나라인 일본, 중국, 러시아는 경제력이나 국력 등에서 세계를 주도하는 나라들이다. 이들은 과학기술분야, 특히 우주분야에서 선두를 다투는 국가들이다. 그에 비해 우리는 새로운 발사체 개발이 중반에 들어섰고, 새로운 발사장 구축도 한창인 수준이다. 본 논문에서는 러시아 기술을 근간으로 하고 있는 러시아와 중국의 발사장의 현황을 알아보고, 이를 통하여 한국형발사체 발사대구축 및 향후 기대되는 미래 발사체 구축에 참고로 삼고자 한다.

• 대한통합의학회지
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• 제10권4호
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• pp.23-34
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• 2022

Purpose : This study examined the effects of pain, neck dysfunction, psychosocial level, headache impact test (HIT), postural alignment, and trapezius muscle tone of the complex exercise program using dynamic taping in patients with tension headache and chronic neck pain with forward head posture. Methods : The design of this is a randomized controlled trial (RCT). Thirty-four patients with chronic neck pain were screened using a randomized assignment program and assigned to experimental group (n=17) and control group (n=17). Both groups underwent a complex exercise program. In addition, the experimental group dynamic taping was applied to the upper trapezius muscle. All interventions were applied three times per week for four weeks. The visual analogue scale (VAS), the neck disability index (NDI), short form-12 health survey questionnaire (SF-12), Headache impact test-6 (HIT-6), Craniovertebral angle (CVA), Cranial rotation angle (CRA), upper trapezius muscle tone were compared to evaluate the effect on intervention. Results : Both groups showed significant differences before and after the intervention in VAS, NDI, SF-12, HIT-6, and CVA, CRA (p<.05). In addition, significant differences in NDI and upper trapezius muscle tone were observed between the experimental group and control group (p<.05). Conclusion : A complex exercise program using dynamic taping for patients with tension headache and chronic neck pain with forward head posture are effective method with clinical significance in improving the function and reducing upper trapezius muscle tone.

• 대한산업공학회지
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• 제1권2호
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• pp.51-56
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• 1975

A computer program for computing complex system reliability is described. The program is composed of three phases : Phase I program reduces all series, parallel and series-parallel components and subsequently obtains an irreducible non-series-parallel system. Phase II program enumerates all the possible paths from the source to the sink of the graph. Phase III program then computes system reliability based on the information obtained by the Phase II program. The program is based on a modified version of the algorithm published in [6]. An example of the use of the computer program is given.

• 한국산학기술학회논문지
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• 제13권4호
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• pp.1684-1689
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• 2012

본 연구는 퇴행성 슬관절염을 가진 노인 환자에게 복합운동 프로그램을 적용하여 통증과 근활성도에 미치는 영향을 알아보고자 하였다. B병원에 입원한 환자 중 퇴행성 슬관절염 진단을 받은 노인 환자 23명을 대상으로 운동군(n=12)과 통제군(n=11)으로 나누어 두 집단 모두 온열 및 전기치료를 포함한 물리치료를 40분간, 주 3회, 10주간 실시하였고, 운동군에는 추가로 복합운동 프로그램을 주 3회, 40분간, 10주간 적용하였으며, 훈련 전과 후의 VAS와 근활성도를 측정하였다. 실험(10주)후의 결과는 다음과 같이 나타났다. 첫째, 운동군과 통제군 모두에서 실험전보다 실험 후에 통증에 유의한 차이를 보였다(p<0.05). 하지만, 두 군 간의 유의한 차이는 없었다(p>0.05). 둘째, 운동군에서 실험전보다 실험 후에 근활성도에 유의한 차이를 보였고(p<0.05), 운동군과 통제군 사이에서도 유의한 차이가 있었다(p<0.05). 본 연구 결과를 통하여 퇴행성 슬관절염을 가진 노인 환자에게 복합운동 프로그램이 통증과 근활성도에 효과가 있는 것으로 나타났다. 향후 퇴행성 슬관절염 환자에게 복합운동뿐만 아니라 유산소운동, 저항성 운동프로그램 등을 접목시켜 노인환자들이 손쉽게 할 수 있는 흥미로운 프로그램을 만들어 노인들의 삶의 질을 높일 수 있는 프로그램에 대한 연구가 계속 이루어져야 할 것이다.

• 한국철도학회:학술대회논문집
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• 한국철도학회 2010년도 춘계학술대회 논문집
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• pp.1791-1797
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• 2010

The Urban Transit Standardization Program has been supported by the Ministry of Land, Transport and Maritime Affairs. The Program consists of dozen or more projects and thus is quite complex, which implies that the program success heavily depends upon the effective management of various artifacts during the development. Particularly, in the complex systems development, developing and managing requirements is very important throughout the whole system life cycle. The requirements can be the basis of the design changes to be made later as well as the test and evaluation to be performed in the subsequent stages of the systems development. As such, the derivation of the system's requirement based on the needs from the customers, or stakeholder in a broad sense must be done properly. In particular, notice that the system is being developed but the system requirements are not fully available for some reasons. To complement this situation is the purpose of the study. To derive proper requirements effectively in the process of development, this paper proposes to draw up scenario using the output of the system under development and to utilize the use case diagrams and operational scenarios.

• 대한설비공학회:학술대회논문집
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• 대한설비공학회 2006년도 하계학술발표대회 논문집
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• pp.363-368
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• 2006

The purpose of this case study is to analyze stack effect problems and to develop methods minimizing methods of stack effect in the tall complex building in cold climates. The main problems in the tall complex building occur in high-rise elevators. Such problems as elevator doors that do not close and exhaust airflows result in excessive pressure differences across elevator doors due to stack effect. Under the expected conditions causing these pressure differences, computer simulations with CONTAMW computer program and field measurements are performed in the tall complex building. The results are analyzed in architectural design aspects. With these analysis, the tall complex building design guidelines to minimize stack effect are proposed.

• Bulletin of the Korean Chemical Society
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• 제32권12호
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• pp.4321-4326
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• 2011

A new series of heteroleptic cyclometalated iridium(III) complexes has been synthesized and characterized by absorption, emission and cyclic voltammetry studies: $(pqx)_2Ir(acac)$ (1), $(dmpqx)_2Ir(acac)$ (2) and $(dfpqx)_2Ir(acac)$ (3) where pqx=2-phenylquinoxalinate, dmpqx=2-(2,4-dimethoxyphenyl)quinoxalinate, dfpqx=2-(2,4-difluorophenyl) quinoxalinate and acac=acetylacetonate anion. The reaction of excess acetylacetone with ${\mu}$-chloride-bridged dimeric iridium complex, $[(C\^N)_2Ir({\mu}-Cl)]_2$, gives a complex 1 and an unusual hydridoiridium(III) complex, $(pqx)IrH(acac)_2$ (4). The complex 1, 2 and 3 show their emissions in an orangered region (${\lambda}_{PL,max}$ = 583-616 nm), and the emission maxima can be tuned by the change of substituent at phenyl ring of 2-phenylquinoxaline ligand. The phosphorescent line shape indicates that the emissions originate predominantly from $^3MLCT$ states with little admixture of ligand-based $^3({\pi}-{\pi}^*)$ excited states. The structures of complex 3 and 4 are additionally characterized by a single crystal X-ray diffraction method. The complex 3 shows a distorted octahedral geometry around iridium(III) metal ion. A strong trans influence of the phenyl ring is examined. In complex 4, there are two discrete molecules which are mirror images each other at the ratio of 1:1 in an unit cell. We propose that the phosphorescent complex 1, 2 and 3 are possible candidates for the phosphors in OLEDs applications.

• BMB Reports
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• 제55권12호
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• pp.645-650
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• 2022

Epithelial-to-mesenchymal transition (EMT)-subtype gastric cancers have the worst prognosis due to their higher recurrence rate, higher probability of developing metastases and higher chemo-resistance compared to those of other molecular subtypes. Pharmacologically actionable somatic mutations are rarely found in EMT-subtype gastric cancers, limiting the utility of targeted therapies. Here, we conducted a high-throughput chemical screen using 37 gastric cancer cell lines and 48,467 synthetic small-molecule compounds. We identified YK-135, a small-molecule compound that showed higher cytotoxicity toward EMT-subtype gastric cancer cell lines than toward non-EMT-subtype gastric cancer cell lines. YK-135 exerts its cytotoxic effects by inhibiting mitochondrial complex I activity and inducing AMP-activated protein kinase (AMPK)-mediated apoptosis. We found that the lower glycolytic capacity of the EMT-subtype gastric cancer cells confers synthetic lethality to the inhibition of mitochondrial complex I, possibly by failing to maintain energy homeostasis. Other well-known mitochondrial complex I inhibitors (e.g., rotenone and phenformin) mimic the efficacy of YK-135, supporting our results. These findings highlight mitochondrial complex I inhibitors as promising therapeutic agents for EMT-subtype gastric cancers and YK-135 as a novel chemical scaffold for further drug development.

• 한국소음진동공학회:학술대회논문집
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• 한국소음진동공학회 2001년도 춘계학술대회논문집
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• pp.1050-1055
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• 2001

A software for prediction of apartment noise level ihas been improved. The program is based on the ray tracing technique which has been widely used in the environmental noise analysis and prediction. Especially for prediction of environmental noise in apartment complex, this program is advanced in the graphics routine by bilinear interpolation. In this paper, we analyze the railway noise distribution in apartment environment and develop a 3D graphics routine for illustrating the noise level.

• Corrosion Science and Technology
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• 제12권2호
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• pp.79-84
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• 2013

In general, pipelines at nuclear power plants are affected by various types of degradation mechanisms and may be ruptured after gradually thinning. FAC (Flow-Accelerated Corrosion) is typical aging mechanism affecting the secondary side piping system. In Korea nuclear power plants, CHECWORKS program have been used for management of wall thinning damages. However, sometimes, CHECWORKS program shows wrong results at the stage of NFA (Network Flow Analysis) in case of complex pipelines. This paper describes the calculation results of pressure drop in a complex pipeline and single line by using the CHECWORKS program and the analysis results are compared with those of engineering calculation results including errors between them.