• Bulletin of the Korean Chemical Society
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• 제22권4호
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• pp.379-382
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• 2001

A new ligand containing the long aliphatic hydrocarbon chain, dipyridylstearylamine (dps) and its copper(Ⅱ) complex, Cu(dps)(NO3)2 have been prepared. The copper complex was characterized structurally and spectroscopically. The XRD crystal structure of the copper complex reveals that copper is octahedrally coordinated by dps and two nitrato ligands. The nitrato groups ligate asymmetrically to the copper. Crystal data are P1bar, a=8.249(2), b=10.416(3), $c=20.915(4)\AA$, $\alpha=86.54(2)$, $\beta=84.026(2)$, $\gamma=72.32(2)^{\circ}$, V=1702.7(7) $\AA3$ , Z=2, ${\lambda}$(Mo $K\alpha)=0.71073\AA$, $\mu=0.689$ mm-1 , T=293(2) K, R=0.0560 for 3529 reflections. The dps and the copper complex are stable in the air and the copper complex exhibits features of typical of other copper(Ⅱ) complexes containing dipyridylamine-based ligand.

• 한국멀티미디어학회논문지
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• 제22권1호
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• pp.18-26
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• 2019

In this paper we propose how to detect circular objects in the gray scale image and segment them using the discrete Morse theory, which makes it possible to analyze the topology of a digital image, when it is transformed into the data structure of some combinatorial complex. It is possible to get meaningful information about how many connected components and topologically circular shapes are in the image by computing the persistent homology of the filtration using the Morse complex. We obtain a Morse complex by modeling an image as a cubical cellular complex. Each cell in the Morse complex is the critical point at which the topological structure changes in the filtration consisting of the level sets of the image. In this paper, we implement the proposed algorithm of segmenting the circularly shaped objects with a long persistence of homology as well as computing persistent homology along the filtration of the input image and displaying in the form of a persistence diagram.

• Biodesign
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• 제6권4호
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• pp.92-95
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• 2018

API5 is a unique oncogenic, non-BIR type IAP nuclear protein and is up-regulated in several cancers. It exerts several functions, such as apoptosis inhibition, cell cycle progression, cancer immune escape, and anticancer drug resistance. Although structural studies of API have revealed that API5 mediates protein-protein interactions, its detailed molecular functions remain unknown. Since FGF2 is one of API5's major interacting proteins, structural studies of the API5-FGF2 complex will provide insight into both proteins' molecular function. We overexpressed and purified API5 and FGF2 in Escherichia coli and crystallized the API-FGF2 complex using polyethylene glycol (PEG) 6000 as a precipitant. Diffraction data were collected to a $2.7{\AA}$ resolution using synchrotron X-rays. Preliminary diffraction analysis revealed that the API5-FGF2 complex crystal belongs to the space group $P2_12_12_1$ with the following unit cell parameters: a = 46.862, b = 76.523, $c=208.161{\AA}$. One asymmetric unit with 49.9% solvent contains one API5-FGF2 complex. Molecular replacement calculation, using API5 and FGF2 coordinates, provided a clear electron density map for an API5-FGF2 complex.

• 한국화재소방학회논문지
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• 제25권4호
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• pp.42-47
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• 2011

본 연구에서는 환기 및 소방용 복합댐퍼의 개발을 위한 기초 연구의 일환으로 복합댐퍼의 설계인자에 관한 연구를 수행하였다. 본 연구는 복합댐퍼의 프로세스와 운동 메커니즘, 기구 모델링을 바탕으로 복합댐퍼의 설계 및 해석이론을 제시하였고, 설계 및 해석이론을 바탕으로 한 운동해석 시뮬레이션을 통해 복합댐퍼의 각 요소를 설계할 수 있는 엔지니어링 데이터 구축과 원천기술을 확립하였다. 따라서 본 연구를 통해 환기 및 소방용 복합댐퍼 개발에 폭넓게 응용할 수 있는 결과를 얻었다. 본 연구를 바탕으로 복합댐퍼가 개발되면 환기풍도로부터 유입되는 연기제어와 기술적 대책을 마련할 수 있을 것으로 본다.

• BMB Reports
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• 제52권10호
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• pp.607-612
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• 2019

During meiosis, programmed double-strand breaks (DSBs) are repaired via recombination pathways that are required for faithful chromosomal segregation and genetic diversity. In meiotic progression, the non-homologous end joining (NHEJ) pathway is suppressed and instead meiotic recombination initiated by nucleolytic resection of DSB ends is the major pathway employed. This requires diverse recombinase proteins and regulatory factors involved in the formation of crossovers (COs) and non-crossovers (NCOs). In mitosis, spontaneous DSBs occurring at the G1 phase are predominantly repaired via NHEJ, mediating the joining of DNA ends. The Ku complex binds to these DSB ends, inhibiting additional DSB resection and mediating end joining with Dnl4, Lif1, and Nej1, which join the Ku complex and DSB ends. Here, we report the role of the Ku complex in DSB repair using a physical analysis of recombination in Saccharomyces cerevisiae during meiosis. We found that the Ku complex is not essential for meiotic progression, DSB formation, joint molecule formation, or CO/NCO formation during normal meiosis. Surprisingly, in the absence of the Ku complex and functional Mre11-Rad50-Xrs2 (MRX) complex, a large portion of meiotic DSBs was repaired via the recombination pathway to form COs and NCOs. Our data suggested that Ku complex prevents meiotic recombination in the elimination of MRX activity.

• 한국위성정보통신학회논문지
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• 제10권3호
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• pp.11-15
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• 2015

본 연구에서는 수재해 정보 플랫폼 내 자료처리 시스템 설계를 위해 자료처리 과정의 복잡도를 분석하고 이에 따른 설계 방안을 제시하였다. 일반적으로 자료를 수집하고 분석하는 시스템은 자료와 알고리즘의 자료처리 과정이 고정된 고정 자료-알고리즘 자료처리 방식을 사용한다. 하지만 시스템의 복잡도가 증가하면 자료처리 시스템에서 관리해야 하는 자료처리 과정의 수가 급증하는 문제가 발생한다. 이를 해결하기 위해 자료와 알고리즘 사이에 인터페이스가 존재하는 동적 자료-알고리즘 자료처리 방식을 적용할 수 있다. 각 방식의 장단점을 분석한 뒤, 수재해 정보 플랫폼에 최적화된 자료처리 시스템의 설계안을 제시할 수 있었다.

• 한국정보통신학회논문지
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• 제20권1호
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• pp.123-130
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• 2016

본 논문에서는 멀티미디어용 알고리즘을 고속으로 처리하기 위한 고성능 연산 회로를 설계하였다. 3단 파이프라인 구조로 동작하는 연산회로는 4개의 16-비트${\times}$16-비트 곱셈기의 효율적인 구성, 캐리 보존 형식 데이터에 대한 새로운 부호 확장 기법과 다수 개의 부분 곱셈 결과의 통합과정에 부호 확장을 제거하는 교정 상수 기법을 사용하여 복소수 데이터와 가변 길이 고정 소수점 데이터에 대한 38개의 연산을 처리할 수 있다. 설계한 프로세서는 45nm CMOS 공정에서 최대 동작 속도는 300 MHz이며 약 37,000 게이트로 구성되며 300 MCOPS의 연산 성능을 갖는다. 연산 프로세서는 높은 연산 속도와 응용 분야에 특화된 다양한 연산 지원으로 멀티미디어 프로세서에 효율적으로 응용 가능하다.

• Journal of Korean Biological Nursing Science
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• 제22권1호
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• pp.53-60
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• 2020

Purpose: This study used raw data from the fifth (2010-2012) Korea National Health and Nutrition Examination Survey (KNHANES) to assess the relationship between vitamin D level and glycemic control of diabetes, and to provide basic data about the use of vitamin D for preparation of a treatment plan for diabetes in South Korea. Methods: For this study, data of 1,713 diabetes from KNHANES (2010-2012) were used. The collected data were analyzed using SPSS 18.0 program, and complex sample frequency analysis, descriptive statistics, complex sample cross analysis, complex sample general linear regression, and complex sample logistic regression analysis were performed. Results: It was found that the poor glycemic control group among the diabetes subjects had significantly lower level of blood vitamin D than the good glycemic control group. Factors affecting glycemic control included drinking, vitamin D levels, hypertriglyceridemia, duration of diabetes, and treatment of diabetes. Also, diabetics with vitamin D deficiency or shortage showed 3.55- and 2.61-times higher odds ratios, respectively, to be diagnosed as the poor glycemic control group than diabetics without vitamin D deficiency or shortage. Conclusion: This study is significant because it provides rationale and basic data about the use of vitamin D for preparation of a treatment plan for diabetes in South Korea by assessing the dependence of glycemic control on the vitamin D level of diabetics. Additionally, future studies are necessary to determine the appropriate concentration of vitamin D for diabetes prevention and treatment to prevent the side effects of excessive supplementation.

• 산업기술연구
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• 제29권B호
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• pp.181-186
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• 2009

The wind data measured from automated weather stations (AWS) at complex terrains in Korea was used to predict the wind velocity at nearby sites that are several kilometers away. The ten-minute averaged wind data was measured at a height of 10 meters. A commercial CFD code, WindSIM, based on the weighted averaged Navier-Stokes equation was employed. The results were compared with the data measured using meteorological masts (MM) at a height of 40 meters. The predictions using the AWS data and WindSIM showed good agreements with the measured data.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제17권7호
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• pp.1894-1915
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• 2023

Software-Defined Networking (SDN) offers several advantages in dynamic routing, flexible programmable control and custom application-driven network management. However, the programmability of the data plane in traditional SDN is limited. A network operator cannot change the ability of the data plane and perform complex packet processing on the data plane, which limits the flexibility and extendibility of SDN. In the paper, AP-SDN (Action Program enabled Software-Defined Networking) architecture is proposed, which extends the action set of SDN data plane. In the proposed architecture, a modified Open vSwitch is utilized in the data plane allowing the execution of action programs at runtime, thus enabling complex packet processing. An example action program is also implemented which transparently encrypts traffic for terminals. At last, a prototype system of AP-SDN is developed and experiments show its effectiveness and performance.