• Title/Summary/Keyword: Complex Data

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The Association between Resistance Exercise Frequency, Muscular Strength, and Health-Related Quality of Life in Korean Cancer Patients: The Korea National Health and Nutrition Examination Survey (KNHANES) 2014-2016 (한국 암환자들의 근력운동 빈도, 근력과 건강관련 삶의 질과의 관계: 국민건강영양조사 2014-2016년)

  • An, Ki-Yong;Kang, Dong-Woo;Min, Ji Hee
    • 한국체육학회지인문사회과학편
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    • v.57 no.5
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    • pp.269-279
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    • 2018
  • The purpose of this study is to examine the association between resistance exercise frequency, muscular strength, and health-related quality of life in Korean cancer patients. We performed complex sample general linear model and logistic regression analysis using data from a total of 647 cancer patients in the 2014~2016 Korean National Health and Nutrition Examination Survey (KNHANES). Participants who were participating in resistance exercise 0~1 day per week had lower EQ-5D index (0.852±0.016 vs. 0.890±0.020; p=0.006) and a significantly higher risk of having problems in mobility (Odd ratio[OR]=4.07; 95% confidence interval [CI]=1.31-12.63) compared to those who were participating in resistance exercise ≥ 5 days per week. Participants with low hand-grip strength had lower EQ-5D index (0.850±0.018 vs. 0.911±0.016; p<0.001) and a significantly higher risk of having problems in mobility (OR=4.94, 95% CI=2.14-11.41), usual activities (OR=5.18, 95% CI=1.56-17.14), and pain/discomfort (OR=2.46, 95% CI=1.33-4.55) compared to those with high hand-grip strength. This study showed that resistance exercise frequency and muscular strength were associated with health-related quality of life in Korean cancer patients.

Relationship between Health Behaviors and Physical Activity for Adolescents' Life Care (청소년의 생활습관관리를 위한 신체활동과 건강행위와의 관련성 연구)

  • Han, Geun-Hye
    • Journal of Korea Entertainment Industry Association
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    • v.13 no.5
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    • pp.127-138
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    • 2019
  • This study was a secondary data analysis using statistics from the 13th (2017) Korea Youth Risk Behavior Web-based Survey (KYRBS) to investigate the relationship between health behaviors and physical activity among Korean adolescents. A total of 62,276 adolescents in middle and high schools enrolled in this study. Physical activity utilized moderate and vigorous physical activity variables. Health behaviors used smoking, drinking, eating, sedentary behavior, and sleep duration variables. Statistical analyses were performed applying complex sample analysis method. Chi-square tests were used to compare physical activity according to health behaviors. Multivariate multinomial logistic regression analyses were conducted to examine the relationship between health behaviors and physical activity, adjusted for general characteristics. Current smoking and current drinking were associated with high levels of moderate and vigorous physical activity. Consuming fruits≥1 times/day, vegetables≥3 times/day, and sweet drinks≥3 times/week were associated with high levels of moderate and vigorous physical activity. Eating breakfast≥5 times/week was associated with high levels of moderate physical activity, but not with vigorous physical activity. Sedentary behavior≥2 hour/day was associated with low levels of moderate and vigorous physical activity. Sleep duration<7 hour/day was associated with high levels of moderate physical activity and low levels of vigorous physical activity. These findings suggest that since there is an interrelationship between health behaviors and physical activity among adolescents, intervention programs aiming at promoting physical activity and healthy lifestyles should consider a multiple behavior approach rather than an individual behavior approach.

The Impact of Late-life Poverty on Self-rated Health: A Mediated Moderation Model of Health Behaviors and Social Support (노후 빈곤이 주관적 건강상태에 미치는 영향: 건강행태와 사회적 지지의 매개된 조절효과 분석)

  • Kim, Jinhyun;Won, Seojin
    • 한국노년학
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    • v.31 no.3
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    • pp.463-478
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    • 2011
  • This study examined the impact of late-life poverty on self-rated health, focusing on the mediating and moderating effects of health behaviors and social support. Despite the significant associations among poverty, health behaviors, and health outcomes, little studies have tested complex structural pathways among them. Thus, the purpose of this study is to identify multiple causal pathways between poverty and self-rated health, mediated and moderated by health behaviors and social support. To test the structural pathways, the structural equation modeling was utilized using the 2006 Korean Longitudinal Study of Aging data. The results of this study indicated that poverty had the direct negative impact not only on the health behaviors such as smoking and lack of regular exercise but also on the self-rated health. In addition, regular exercise significantly mediated the relationship between poverty and self-rated health. Finally, informal social support from family and friends buffered the negative impact of poverty on the self-rated health. Findings suggested that providing informal social support to the low income elderly is important in addition to the economic support. It is also necessary to develop programs for promoting healthy behaviors, especially regular exercise.

Global Transcriptome-Wide Association Studies (TWAS) Reveal a Gene Regulation Network of Eating and Cooking Quality Traits in Rice

  • Weiguo Zhao;Qiang He;Kyu-Won Kim;Feifei Xu;Thant Zin Maung;Aueangporn Somsri;Min-Young Yoon;Sang-Beom Lee;Seung-Hyun Kim;Joohyun Lee;Soon-Wook Kwon;Gang-Seob Lee;Bhagwat Nawade;Sang-Ho Chu;Wondo Lee;Yoo-Hyun Cho;Chang-Yong Lee;Ill-Min Chung;Jong-Seong Jeon;Yong-Jin Park
    • Proceedings of the Korean Society of Crop Science Conference
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    • 2022.10a
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    • pp.207-207
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    • 2022
  • Eating and cooking quality (ECQ) is one of the most complex quantitative traits in rice. The understanding of genetic regulation of transcript expression levels attributing to phenotypic variation in ECQ traits is limited. We integrated whole-genome resequencing, transcriptome, and phenotypic variation data from 84 Japonica accessions to build a transcriptome-wide association study (TWAS) based regulatory network. All ECQ traits showed a large phenotypic variation and significant phenotypic correlations among the traits. TWAS analysis identified a total of 285 transcripts significantly associated with six ECQ traits. Genome-wide mapping of ECQ-associated transcripts revealed 66,905 quantitative expression traits (eQTLs), including 21,747 local eQTLs, and 45,158 trans-eQTLs, regulating the expression of 43 genes. The starch synthesis-related genes (SSRGs), starch synthase IV-1 (SSIV-1), starch branching enzyme 1 (SBE1), granule-bound starch synthase 2 (GBSS2), and ADP-glucose pyrophosphorylase small subunit 2a (OsAGPS2a) were found to have eQTLs regulating the expression of ECQ associated transcripts. Further, in co-expression analysis, 130 genes produced at least one network with 22 master regulators. In addition, we developed CRISPR/Cas9-edited glbl mutant lines that confirmed the role of alpha-globulin (glbl) in starch synthesis to validate the co-expression analysis. This study provided novel insights into the genetic regulation of ECQ traits, and transcripts associated with these traits were discovered that could be used in further rice breeding.

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Application of the EIASS for Assessing Changes in Terrain Features in Development Initiatives: A Case Study in South Korea (환경영향평가정보지원시스템(EIASS)을 활용한 국내 주요 개발사업의 지형변화 검토)

  • Sujung Heo;Dong Kun Lee;Eunsub Kim
    • Journal of Environmental Impact Assessment
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    • v.32 no.6
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    • pp.407-418
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    • 2023
  • This study conducted an analysis of terrain change indicators in major development projects in Korea, examining the correlation between terrain change indicators to derive foundational terrain change metrics based on different land use and slope types. The aim is to contribute to sustainable development by enhancing the efficiency of land utilization and landscaping, while minimizing environmental impacts in future development endeavors. Additionally, to apply the research findings in practical contexts, domestic regulations related to terrain were surveyed, and the compatibility and usability between these regulations and research analysis results were discussed. Based on this, the study seeks to explore strategies for more accurate and useful utilization of terrain change indicators in future research. As a result, in the tourism development, terrain changes predominantly occur in the order of flat land, hillly land, and mountain land, with the analysis indicating higher terrain changes in undulating hilly and mountainous lands compared to flat land. Furthermore, in industrial complex development, very steep (20°-30°) and extreme (30°-40°) slopes; in urban development projects, steep slope (15°-20°); in athletic service facility and tourist development, steep (15°-20°) and very steep (20°-30°) exhibit higher average terrain change indicators compared to other slope categories. The findings of our study can contribute to the formulation of strategies aimed at minimizing terrain disturbance in future domestic development projects and serve as foundational data for environmental impact assessments.

Design of Ship-type Floating LiDAR Buoy System for Wind Resource Measurement inthe Korean West Sea and Numerical Analysis of Stability Assessment of Mooring System (서해안 해상풍력단지 풍황관측용 부유식 라이다 운영을 위한 선박형 부표식 설계 및 계류 시스템의 수치 해석적 안정성 평가)

  • Yong-Soo, Gang;Jong-Kyu, Kim;Baek-Bum, Lee;Su-In, Yang;Jong-Wook, Kim
    • Journal of Navigation and Port Research
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    • v.46 no.6
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    • pp.483-490
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    • 2022
  • Floating LiDAR is a system that provides a new paradigm for wind condition observation, which is essential when creating an offshore wind farm. As it can save time and money, minimize environmental impact, and even reduce backlash from local communities, it is emerging as the industry standard. However, the design and verification of a stable platform is very important, as disturbance factors caused by fluctuations of the buoy affect the reliability of observation data. In Korea, due to the nation's late entry into the technology, a number of foreign equipment manufacturers are dominating the domestic market. The west coast of Korea is a shallow sea environment with a very large tidal difference, so strong currents repeatedly appear depending on the region, and waves of strong energy that differ by season are formed. This paper conducted a study examining buoys suitable for LiDAR operation in the waters of Korea, which have such complex environmental characteristics. In this paper, we will introduce examples of optimized design and verification of ship-type buoys, which were applied first, and derive important concepts that will serve as the basis for the development of various platforms in the future.

Analysis of the successful experience in mathematics learning based on grounded theory (근거이론을 통한 수학학습의 성공경험에 대한 분석)

  • Kim, Hong-Kyeom;Ko, Ho Kyoung
    • The Mathematical Education
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    • v.62 no.4
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    • pp.491-513
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    • 2023
  • High achievement in mathematics is a very complex process in which various factors such as cognitive factors, affective factors, and social and environmental factors work respectively and complementary. A number of previous studies conducted so far have shown that there are certain factors affecting math learning and these factors have positive or negative effects on it. However, these studies were conducted with limited variables and it was not possible to present a comprehensive analysis of what would be necessary to get good achievements in mathematics learning. Therefore, in this study, we analyzed the process of experience of students who experienced success in mathematics learning using the analysis method of the grounded theory. In addition, the collected data was analyzed to explain the process of leading to the successful experience in mathematics learning. As a result of the analysis, it was revealed that students form their identity as successful learners through the processes of 'new phase stage', 'experience accumulation stage', 'stand-up stage', and 'maintenance effort stage'. Through this study, we were able to get implications for what actions are needed to experience success in math learning by looking at the process of the experience what interviewees have gone through.

Safety Verification Techniques of Privacy Policy Using GPT (GPT를 활용한 개인정보 처리방침 안전성 검증 기법)

  • Hye-Yeon Shim;MinSeo Kweun;DaYoung Yoon;JiYoung Seo;Il-Gu Lee
    • Journal of the Korea Institute of Information Security & Cryptology
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    • v.34 no.2
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    • pp.207-216
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    • 2024
  • As big data was built due to the 4th Industrial Revolution, personalized services increased rapidly. As a result, the amount of personal information collected from online services has increased, and concerns about users' personal information leakage and privacy infringement have increased. Online service providers provide privacy policies to address concerns about privacy infringement of users, but privacy policies are often misused due to the long and complex problem that it is difficult for users to directly identify risk items. Therefore, there is a need for a method that can automatically check whether the privacy policy is safe. However, the safety verification technique of the conventional blacklist and machine learning-based privacy policy has a problem that is difficult to expand or has low accessibility. In this paper, to solve the problem, we propose a safety verification technique for the privacy policy using the GPT-3.5 API, which is a generative artificial intelligence. Classification work can be performed evenin a new environment, and it shows the possibility that the general public without expertise can easily inspect the privacy policy. In the experiment, how accurately the blacklist-based privacy policy and the GPT-based privacy policy classify safe and unsafe sentences and the time spent on classification was measured. According to the experimental results, the proposed technique showed 10.34% higher accuracy on average than the conventional blacklist-based sentence safety verification technique.

Active Phytochemicals of Indian Spices Target Leading Proteins Involved in Breast Cancer: An in Silico Study

  • Ashok Kumar Krishnakumar;Jayanthi Malaiyandi;Pavatharani Muralidharan;Arvind Rehalia;Anami Ahuja;Vidhya Duraisamy;Usha Agrawal;Anjani Kumar Singh;Himanshu Narayan, Singh;Vishnu Swarup
    • Journal of the Korean Chemical Society
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    • v.68 no.3
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    • pp.151-159
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    • 2024
  • Indian spices are well known for their numerous health benefits, flavour, taste, and colour. Recent Advancements in chemical technology have led to better extraction and identification of bioactive molecules (phytochemicals) from spices. The therapeutic effects of spices against diabetes, cardiac problems, and various cancers has been well established. The present in silico study aims to investigate the binding affinity of 29 phytochemicals from 11 Indian spices with two prominent proteins, BCL3 and CXCL10 involved in invasiveness and bone metastasis of breast cancer. The three-dimensional structures of 29 phytochemicals were extracted from PubChem database. Protein Data Bank was used to retrieve the 3D structures of BCL3 and CXCL10 proteins. The drug-likeness and other properties of compounds were analysed by ADME and Lipinski rule of five (RO5). All computational simulations were carried out using Autodock 4.0 on Windows platform. The proteins were set to be rigid and compounds were kept free to rotate. In-silico study demonstrated a strong complex formation (positive binding constants and negative binding energy ΔG) between all phytochemicals and target proteins. However, piperine and sesamolin demonstrated high binding constants with BCL3 (50.681 × 103 mol-1, 137.76 × 103 mol-1) and CXCL10 (98.71 × 103 mol-1, 861.7 × 103 mol-1), respectively. The potential of these two phytochemicals as a drug candidate was highlighted by their binding energy of -6.5 kcal mol-1, -7.1 kcal mol-1 with BCL3 and -6.9 kcal mol-1, -8.2 kcal mol-1 with CXCL10, respectively coupled with their favourable drug likeliness and pharmacokinetics properties. These findings underscore the potential of piperine and sesamolin as drug candidates for inhibiting invasiveness and regulating breast cancer metastasis. However, further validation through in vitro and in vivo studies is necessary to confirm the in silico results and evaluate their clinical potential.

Experimental Study to Evaluate Thermal and Mechanical Behaviors of Frozen Soils according to Organic Contents (유기물 함유량에 따른 동토 시료의 열적·역학적 거동 평가를 위한 실험적 연구)

  • Sangyeong Park;Hyeontae Park;Hangseok Choi;YoungSeok Kim;Sewon Kim
    • Journal of the Korean Geosynthetics Society
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    • v.23 no.2
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    • pp.53-62
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    • 2024
  • Recently, development of non-traditional energy such as oil sands has been actively conducted in the cold region such as Canada. Frozen soil has different thermal and mechanical characteristics from general soil due to its high organic contents. This study evaluated the impact of organic matter content on the thermal and mechanical behavior of frozen soil samples collected from Alberta, Canada, and Gangwon Province, South Korea. As the organic content increases, the maximum dry unit weight decreases and the optimum moisture content increases in compaction tests. In uniaxial compression tests under frozen conditions, the strength of the frozen specimens increased as the temperature decreased. The strength of Canada soil sample increased with higher organic matter content at low temperatures. However, the strength of frozen soil was not significantly affected by organic matter content due to the complex behavior and unfrozen water content. Thermal conductivity tests showed higher thermal conductivity in frozen conditions compared to unfrozen conditions, due to the higher thermal conductivity of ice compared to water. These findings provide essential data for geotechnical design and construction in large-scale projects such as oil sands development in cold regions. Further research is needed to explore the impact of organic matter content on different types of frozen soils.