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Clinical Trial to Evaluate the Hot Flush Relief Efficacy and Safety of Yiseontang-gami in Climacteric Women with Hot Flushes (갱년기 여성의 안면홍조에 대한 이선탕가미방(二仙湯加味方)의 증상 완화 효과 및 안전성 평가를 위한 임상연구)

  • Jung, Su-Kyoung;Kim, Dong-Il
    • Journal of Oriental Medical Thermology
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    • v.7 no.1
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    • pp.1-13
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    • 2009
  • Purpose: To evaluate the hot flush relief efficacy of Yiseontang-gami in climacteric women with hot flushes, a vasomotor symptom. Methods: The 20 subjects who signing on the clinical trial written consent by self-will is registered this clinical trial after decided suitable by selection and exception standard, after take a medical experiment and checkup according to clinical trial plan. Registered subject should valuated by settled schedule after take the testing medicine(Yiseontang-gami)during thirty-day. The evaluating indexes of this trial are hot flush VAS, hot flush frequency, hot flush consistence time, sweating VAS, palpitation VAS, sleep disturbance VAS, MRS, MENQOL, PGA. Results: The results were as follows 1. 4 subjects dropped out of the clinical trial and 16 subjects completed it. 2. After Yiseontang-gami treatment, hot flush VAS, hot flush frequent, sweating VAS, Palpitation VAS, sleep disturbance VAS improved significantly. 3. After Yiseontang-gami treatment, hot flush consistence time was not improved significantly. 4. After Yiseontang-gami treatment, blood test value were not different significantly. Conclusion: In this clinical trial we consider that Yiseontang-gami is suitable treatment for the hot flushes and related symptoms.

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A Correlation between the Visual Perception Ability and Activities of Daily Living for Children with Spastic Diplegia (경직형 양하지 뇌성마비아동의 시지각 능력과 일상생활동작과의 관련성 연구)

  • Yu, Byong-Kyu;Jung, Kum-Hee
    • The Journal of Korean Academy of Sensory Integration
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    • v.4 no.1
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    • pp.47-55
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    • 2006
  • Objective : The purpose of this study was to evaluate the correlation between visual perception ability and activities of daily living(ADL) in the children with spastic diplegia who were treated at developmental disabilities children salutary institute. Method : The subject were consisted of 8 children with spastic diplegia(mean age, 10). The visual perception ability was measured by the Developmental Test of Visual Perception(DTVP) and by the Functional Independence Measure for Children(WeeFIM) to evaluate activities of daily living. Collected data analysis were completed by using correlation analysis. Results : Visual perception ability of children with spastic diplegia is the highest in Position in Space(PS) score, and is the lowest in Visual-Motor coordination(VM) score. Average visual perception performance of children with spastic diplegia is the highest in SR(Spatial relationship) score, and is the lowest in VM score. In activities of daily living, eating component were significantly correlated with Visual-Motor coordination. Conclusions : Therefore, accurate evaluation of visual perception ability and visual perception training for children with spastic diplegia will be important to improve patient's activities of daily living skill.

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A Rasch Analysis of the Korean Version of Oswestry Disability Questionnaire According to General Characteristics of Patients With Low Back Pain (요통환자의 일반적 특성에 따른 한국어판 오스웨스트리 장애 설문지의 라쉬분석)

  • Kim, Gyoung-Mo;Park, So-Yeon;Yi, Chung-Hwi
    • Physical Therapy Korea
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    • v.18 no.2
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    • pp.35-42
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    • 2011
  • Three hundred and fourteen low back pain patients completed the Korean version of the Oswestry Disability Questionnaire (KODQ) and the Rasch analysis was then applied to identify the inappropriate items and to determine ODQ item difficulties according to a subject's characteristics. For women and youths, the 'sex life' item showed misfit statistics, whereas for older subjects it was the 'pain intensity' and 'standing' items. Also, in the acute low back group the 'pain intensity', 'standing' and 'sex life' items showed misfit statistics. For all subjects, the most difficult item was 'pain intensity', whereas the easiest item was 'walking'. But for the older and acute groups 'lifting' was the most difficult item and for those who have a visual analogue scale score of 3 or less 'sitting' was the most difficult item. These results show that differential item functioning is present in several items according to sex, age, acute and chronic pain, and VAS score. This study may be useful for adjusting the KODQ item difficulties for low back pain patients with different characteristics.

Perception of Nutrition Labeling on Restaurant Menus among Adults in Suwon (수원시 거주 성인의 외식 메뉴 영양표시에 대한 인식)

  • Sohn, Chun-Young
    • Korean Journal of Community Nutrition
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    • v.14 no.4
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    • pp.420-429
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    • 2009
  • The purposes of this study were to investigate the perception of nutrition labeling on restaurant menus, and to analyze the differences among subject's characteristics, eating-out behaviors, and dietary attitudes. Information concerning general characteristics, health status, eating-out behaviors and dietary attitudes of subjects was collected by a structured questionnaire. From January 5th to February 27th in 2009, 406 questionnaires were completed by 157 males and 249 females. Statistical analyses were performed using by SPSS 14.0 package program. The perception of the importance of nutrition labeling was 3.89, while knowledge of whether restaurants provided sufficient nutrition information scored 2.26 indicating that being highly conscious of nutrition labeling, respondents did not view the supplied information as sufficient. Nutritional perception was greater in females and varied in both genders with age and health status. Significant differences concerning the perceptions of nutrition labeling were evident, based on eating-out behaviors and dietary attitudes. The results imply that nutrition labeling on restaurant menus should be based on consumer characteristics. Relevant nutrition labeling might help improve health by encouraging proper dietary habits and providing valuable nutritional information. Recognition of the importance of nutrition labeling and strategic implementation of labeling in menus would be prudent strategies for restaurant managers. (Korean J Community Nutrition 14(4) : 420${\sim}$429, 2009)

Parametric study on dynamic behavior of rectangular concrete storage tanks

  • Yazdanian, Mohsen;Fu, Feng
    • Coupled systems mechanics
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    • v.6 no.2
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    • pp.189-206
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    • 2017
  • Tanks are used to store a wide variety of liquids such as oil, gasoline and water. It is reported that, a large number of tanks have been damaged during severe earthquakes. Therefore, understanding their behavior under earthquake is an important subject for structural engineers. In this paper, a comprehensive study is presented on dynamic response of tanks. A parametric study has been completed on the rectangular storage tanks with aid of finite element method (FEM). Various parameters are investigated, such as; liquid height, density and earthquake with different peak ground acceleration (PGA). When investigating these parameters, modal and time history method is used. Six different earthquake records are used for time history analysis. The analysis results show that when the PGA increases by 10.7 times, the maximum displacements, stress, sloshing and base shear increase by 11.4, 22.6, 5.46 and 17.8 times, respectively and when the liquid height increases by two times, the absolute maximum values of stress, displacements, base shear and sloshing increase 1.65, 2.04, 2.05 and 1.34. Furthermore, values of sloshing increase with decrease in density.

Effect of Protease Inhibitors on Degradation of Recombinant Human Epidermal Growth Factor in Skin Tissue

  • Ryou, Hae-Won;Lee, Jang-Won;Kyung, Kyung-Ae;Park, Eun-Seok;Chi, Sang-Cheol
    • Archives of Pharmacal Research
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    • v.20 no.1
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    • pp.34-38
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    • 1997
  • Recombinant human epidermal growth factor (rhEGF), a polypeptide of 53 amino acid residues, is subject to degradation by numerous enzymes, especially proteases, when it is applied on the skin for the treatment of open wound. Amastatin, aprotinin, bestatin, EDTA, EGTA, gabexate, gentamicin, leupeptin, and TPCK were investigated for the possible protease inhibitors, which may use to protect rhEGF from degradation by the enzymes in the skin. Skin homogenates containing protease inhibitors and rhEGF were incubated at $37^{\circ}C$ for 30 minutes. After the reaction was stopped with trifluoroacetic acid, the amount of rhEGF remaining in the sample was determined with an HPLC method. The percentages of rhEGF degraded, at the skin/PBS ratio of 0.25, in the mouse, rat, and human skin homogenate were 85%, 70%, and 46%, respectively. The degree of degradation of rhEGF in the cytosolic fraction was higher than that in the membrane fraction and these enzyme reactions were completed in 30 minutes. Bestatin, EGTA, and TPCK showed significant inhibitory effects on the degradation of rhEGF in the two fractions (p<0.05), while the other protease inhibitors had no significant inhibitory effects or, even resulted in deleterious effects. Therefore, the formulation containing one or several inhibitors among these effective inhibitors would be a promising topical preparation of rhEGF for the treatment of open wound.

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The monrningness-eveningness questionnaire in Korean version and Its relations with sleep-wake habits (한국어판 아침-저녁형 질문지 및 수면습관과의 연관성에 대한 연구)

  • ;;松本一彌
    • Journal of the Ergonomics Society of Korea
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    • v.15 no.2
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    • pp.37-49
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    • 1996
  • Morningness-Eveningness Questionnaire (MEQ) of Horne & Ostberg(1976) was translated into a Korean version, and MEQ and life habit inventory was administrated with approximately 900 university students. The distribution of MEQ score was normal. Arising time and bedtine for weekdays and holidays came in the order of morning type, intermediate and evening-type. And the deviation for the evening-type was greatest. Also, the deviation of sleep length for the evening-type was greater than the morning- type. There were tendencies that the bed time and arising time of the male were slightly later than those of the female, and the sleep length of the male was a little longer than that of the female. It also appeared that the arising time was later in the male who completed the military services than those who did not in the chronotype. And the sleep length of the non-served male was longer than that of the served one. Such tendencies noticeably appeared especially the evening-type. The evening-type was subject to heavy variability in bedtime. arising time, and sleep length. The sleep latency of the evening- type was longer and mood on arising was worse. And the ratio of nap or light sleep was higher in these subjects than in others. These results suggested that evening-type students had more irregular and/or flexible sleep-wake habits than the morning-type.

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Task Analysis of Korean Geriatric Care Managers (노인 케어매니저의 직무 분석)

  • Oh Pok-Ja;Kim Il-Ok;Kim Young-Hye;Shin Sung-Rae;Lee Kyoung-Soon;Han Suk-Jung
    • Journal of Korean Academy of Nursing
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    • v.36 no.5
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    • pp.770-781
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    • 2006
  • Purpose: This study was designed to create a job description for Korean geriatric care managers and examine performance frequency, importance, and difficulty of task elements. Method: The sample consisted of 38 geriatric care managers and professors who performed duties related to geriatric care management at community based-facilities in Korea. A survey method was used, and the questionnaire included frequency, importance, and difficulty of task elements in job descriptions using the DACUM method. Using SPSS WIN 10.0, descriptive statistics such as frequency distribution, means, and standard deviation were conducted to examine the subject's general characteristics, frequency, importance, and difficulties of task performance. Result: The Job description of geriatric care managers revealed 10 duties, 34 tasks, and 105 task elements. On all ten duties, the average performance frequency, importance, and difficulty was 2.55, 2.21 and 2.43 respectively. Conclusion: The job description of geriatric care managers includes duty, task, and task elements and the definition of a completed job. Thus we recommend a data based trial to confirm and validate the information gathered.

The First Step Study on the Standardization of the Analysis and Design for Underground BOX-Type Structures (BOX형 지하구조물 해석 및 설계 표준화 연구(1차 연구))

  • Han, Man-Yeop;Park, Hong-Kee;Son, Eun-Jin
    • Proceedings of the Korea Concrete Institute Conference
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    • 2008.11a
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    • pp.883-886
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    • 2008
  • KCI Committee 107 is "Underground Structures Research Committee". The Committee 107completed the first step study on the analysis and design for underground BOX type structures by 2005. In the study, the committee attempted to the standardization of the analysis and design procedure. This is the introduction and summary of the study and the prospective plan on this subject.

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Development of a 3-D Position Measurement Algorithm using 2-D Image Information (2차원 영상 정보를 이용한 3차원 위치 측정 알고리즘 개발)

  • Lee, J.H.;Jung, S.H.;Kim, D.H.
    • Journal of the Korean Society of Manufacturing Process Engineers
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    • v.12 no.5
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    • pp.141-148
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    • 2013
  • There are several problems in the conventional 2-D image processing and 3-D measurement systems. In the case of the 2-D image processing system, it is not possible to detect elevation data. In a 3-D measurement system, it requires a skillful operator and a lot of time for measuring data. Also, there exist data errors depending on operators. The limitation of detecting elevation data in the 2-D image processing system can be solved by laser diodes. In this study an algorithm that measures the accurate data in a subject face to be detected by combining laser diodes and a commercial CCD camera is developed. In the development process, a planar equation is developed using laser diodes and the equation is used to obtain a normal vector. Based on the results, an algorithm that transforms commercial CCD camera coordinates to 3-D coordinates is proposed. The completed measurement method will be applied to replace a manual measurement system for vehicle bodies and parts by an automated system.