• Korean Journal of Clinical Pharmacy
• /
• v.33 no.3
• /
• pp.153-167
• /
• 2023

Objective: Bipolar disorder displays a spectrum of manifestations, including manic, hypomanic, depressive, mixed, psychotic, and atypical episodes, contributing to its chronic nature and association with heightened suicide risk. Creating effective pharmacotherapy guidelines is crucial for managing bipolar disorder and reducing its prevalence. Treatment algorithms grounded in science have improved symptom management, but variations in recommended medications arise from research differences, healthcare policies, and cultural nuances globally. Methods: This study compares Korea's bipolar disorder treatment algorithm with guidelines from the UK, Australia, and an international association. The aim is to uncover disparities in key recommended medications and their underlying factors. Differences in CYP450 genotypes affecting drug metabolism contribute to distinct recommended medications. Variances also stem from diverse guideline development approaches-expert consensus versus metaanalysis results-forming the primary differences between Korea and other countries. Results: Discrepancies remain in international guidelines relying on meta-analyses due to timing and utilized studies. Drug approval speeds further impact medication selection. However, limited high-quality research results are the main cause of guideline variations, hampering consistent treatment conclusions. Conclusion: Korea's unique Delphi-based treatment algorithm stands out. To improve evidence-based recommendations, large-scale studies assessing bipolar disorder treatments for the Korean population are necessary. This foundation will ensure future recommendations are rooted in scientific evidence.

• International conference on construction engineering and project management
• /
• 2011.02a
• /
• pp.66-73
• /
• 2011

With rapid industrialization, electric power consumption has been increasing every year in Korea and in other countries. The provision of additional power stations to produce more electricity is one possible response to this steady increase in consumption. Another alternative is to improve the efficiency of existing stations through timely and effective maintenance works. Since the construction of a new power plant involves a large amount of capital as well as difficulties in the selection of sites, the improvement of existing power stations' efficiencies is often a preferred solution. Therefore, this paper focuses on maintenance project management to address this issue. Among several types of maintenance works, this paper concentrates on planned outage maintenance (POM). This focus arises from the critical impact of POM on other maintenance work, as well as the entire process of electricity production. Unlike other maintenance work, POM is done on the basis of mid and long-term plans. In addition, only POM works are conducted during the outage of all power plants. To evaluate the efficiency of POM works, budget data relating to 164 POM projects between 2001 and 2008 was collected from 7 sites in South Korea. Data envelopment analysis (DEA) was selected as a methodology for evaluation. From this analysis, comparative study was used to determine the categories of projects that had performed well, and those with the most optimized budget structures. Moreover, through discussion with industry, this research develops a feasible proposed method by which to enhance the efficiency of POM projects.

• Journal of Advanced Navigation Technology
• /
• v.28 no.3
• /
• pp.272-277
• /
• 2024

In most countries, instrument flight procedures are designed by applying one of the following standards: the International Aviation Organization's DOC 8168, Air Navigation Services and Operation Procedures (PANS-OPS), or the US Federal Aviation Administration's TERPS, Terminal Procedures. In particular, the circling approach procedure has many differences between the two standards, and the US terminal procedure (TERPS) has become more complicated since 2013 by applying expanded standards depending on altitude. The circling approach procedures are more risky than straight-in approach procedures because it involves maneuvering the aircraft close to the ground at low energy for landing. In order to accurately understand these differences, this study provides to distinguish by what criteria the circling approach procedure is designed according to individual domestic airports in Korea, to calculate the radius for the range of circling approach areas that guarantee minimum obstacle avoidance during circling approach maneuvers, and to present methods for performing safe circling approach procedures.

• The Journal of the Korea Contents Association
• /
• v.11 no.12
• /
• pp.152-161
• /
• 2011

This study examines characteristics of sports movies between Korea and the U.S. Especially, this paper focuses on three different characteristics including structural, internal characteristics and performance of sports movies. The major results are as follows: firstly, there were similarities between two countries in terms of opening year, genre, classification but movie subjects. More specifically, movie opening years were not related to global sports events. In addition, most sports movies were mainly produced by human genre and all age movie classification. However, in terms of sports subjects, although Korean movies were constructed by baseball game, the U.S. movies were based on football game. Secondly, there were also similarities between both sports movies in terms of external characteristics such as gender difference of hero or heroine, internal story structure and their story sources. Most of sports movies have used real stories as movie story. Finally, although many of the U.S. sports movies recorded the high degree of expenditures, three movies recorded the high degree of movie consumption.

• Journal of Korean Elementary Science Education
• /
• v.41 no.2
• /
• pp.283-294
• /
• 2022

Although the concept of light is important in the elementary school curriculum, substantial research suggests that students and teachers have difficulties in understanding it. Therefore, it is necessary to analyze the reasons for these difficulties-whether it is due to the content or due to the presentation method of contents, structure, and expression. The national curriculum and textbooks of Korea, the US, China, and Japan were comparatively analyzed from the following perspectives: 1) key concepts of light, 2) structure of light units in the textbook, 3) materials, light sources, and optics used in light units. Consequently, there were differences between countries in their inclusion of the concept of light in the curriculum. In particular, the Korean curriculum studies the concept of refraction by a convex lens, whereas the concept of light, light source, and vision is not introduced. Furthermore, countries also differed in their structuring of units. The Korean curriculum was presented segmentally by concept rather than structured according to core ideas or perspectives, and the connection between concepts was unclear. In addition, there were differences between the countries in materials, light sources, and optical instruments to explain key concepts. On using light, the US curriculum provides a purpose and uses light to achieve it, and China and Korea understand the concept. It was divided into the method of using the material to deepen. Based on the results of this analysis, the implications for the elementary science curriculum in Korea were derived as follows. First, it is necessary to introduce concepts sequentially and organize them so that the connection between concepts is well expressed. Second, it is necessary to introduce light and light sources as the predominant concepts. Third, it is necessary to include the principle of seeing objects. Fourth, it is necessary to adjust the material and content level of the refraction concept included in the light and lens unit. Fifth, an integrated approach is required because light has a deep connection with various concepts included in the elementary science curriculum.

• Asian Pacific Journal of Cancer Prevention
• /
• v.14 no.12
• /
• pp.7607-7611
• /
• 2013

Background: Cervical cancer continues to be a major problem in Bangladesh with approximately 18,000 new cases annually of which over 10,000 women die from it. Visual inspection of the cervix after 3-5% acetic acid (VIA) application is a simple and easy to learn method for cervical cancer screening, although cytology-based screening is more often applied in developed countries where it has successfully reduced the prevalence of cervical cancer. Objective: To compare the efficacy of VIA and cytology-based primary methods for cervical cancer screening in Bangladesh. Materials and Methods: This hospital based comparative study was conducted at the VIA centre and Colposcopy Clinic of Bangabandhu Sheikh Mujib Medical University (BSMMU) from October 2008 to October 2010. Results: Among 650 women, 74 (11.4%) were VIA+ve and 8 (1.2%) had abnormalities in their Pap smear reports. During colposcopy, 38 (7.7%) women had different grades of CIN and 4 (0.6%) had cervical cancer. The gold standard histology findings proved 20 women had CIN I, 14 had CIN II/II and 4 had cervical cancer. Among the 38 histology diagnosed abnormalities, VIA test could identify 30 abnormalities including two cervical cancers. However, Pap smear could detect only 8 cases of histological abnormalities (2 low grade and 6 had high grade lesion) and it missed all the cervical cancer cases. The sensitivity and specificity of VIA were 88.9% and 52.1%. The positive predictive value (PPV) and negative predictive value (NPV) were 41.0%, and 92.6% respectively. Moreover, the sensitivity, specificity, PPV and NPV of Pap smear were 33.3%, 95.8%, 75.0% and 79.3%, respectively. Conclusions: VIA test should be used as the primary screening tool even with its low sensitivity and specificity in low resource countries like Bangladesh. False positive results may be greater, but overtreatment can be minimized by colposcopy evaluation of the VIA positive women.

• Korean Journal of Construction Engineering and Management
• /
• v.15 no.3
• /
• pp.12-22
• /
• 2014

In recent, many Korean contractors have tried to extend their business area into the overseas construction market, mainly as a result of a reduction in their domestic construction market. However in terms of risk, overseas construction projects are likely to face a number of unpredictable problems, many of which occur as a result of differences in contract cultures and construction environments between Korea and other countries. One key issue facing overseas construction projects in particular, is that of sub-contracting and control, and the way in which many countries of Commonwealth of Nations operate a unique subcontracting method well known as a nominated sub-contractor(NSC). This paper introduces the NSC system and differences as comparing among standard construction contract forms, such as JCT, SIA, HKIA and PAM. in UK and Asian Commonwealth of Nations. Also, we attempt to classify the type of the NSC system through the consideration of NSC clauses in accordance with the objection and termination of NSC contracting respectively.

• The Southeast Asian review
• /
• v.28 no.4
• /
• pp.31-76
• /
• 2018

This article explores why the two Southeast Asian countries, Vietnam and the Philippines, choose different strategies to cope with the Chinese threat. Despite the evident Chinese threat in the South China Sea, Vietnam has not meaningfully expanded the military cooperation with the United States, whereas the Philippines, ironically, has distanced itself with its ally, the United States. Existing studies on the topic does not offer a satisfactory explanation. We assign that two cases are examples of "underbalancing" - the failure of balancing even though there is an evident threat. Furthermore, we demonstrate the difference between cases of the Philippines and Vietnam by arguing that the number of veto players affects the outcome of foreign policy, underbalancing of two countries. The Philippines has only one veto player, the president, hence its response to external threats is incoherent. On the other hand, the number of veto players in Vietnam is more than one and those players demand negotiation among them on the matter of foreign policy. Upon analyses on two cases we argue that the former is the case of underbalancing caused by a lack of policy stability, while the latter is the case of underbalancing caused by a lack of policy responsiveness.

• International Area Studies Review
• /
• v.15 no.1
• /
• pp.549-570
• /
• 2011

The purpose of this article is to review the current states and future trends in the more developed countries(MDC), the less developed countries(LDC), and Korea. In 2009, the percentage of persons ages 65 and older in the world's population is 8%. However, the ratio of elderly to the total population is higher in MDC than LDC (and Korea). In future, population ageing will be a serious social problem in the LDC (and Korea). Population ageing process will occur at a much faster rate in LDC (and Korea). The reason is that the demographic transition in LDC (and Korea) has occurred in much shorter and recent periods. Though the ageing indices such as the old-age dependency ratio, aging index, and the median ages are higher in MDC, they will change rapidly in LDC. In addition, the oldest old population will increase in LDC than MDC. Therefore, when establishing the government policy related to population ageing, we need to consider the different population ageing process between in MDC and in Korea(or LDC).

• Journal of Crop Science and Biotechnology
• /
• v.11 no.1
• /
• pp.17-22
• /
• 2008

Aromatic rice has become popular owing to its aroma. Growing demand for aromatic rice has spurred interest in the development of domestic cultivars that offer similar combinations of grain attributes such as texture, cooking characteristics, aroma, and taste. In this study, the most important agronomic attributes and aroma of 26 cultivars from Afghanistan, Iran, and Uzbekistan, and controls from Japan, Thailand, and India were characterized. Also $F_2$ populations derived from the cross between(Jasmine 85 aromatic$\times$Nipponbare non-aromatic) and(Jasmine 85$\times$Basmati 370 aromatic) were obtained. Tasting individual grains, cooking test, 1.7% KOH sensory test, and molecular marker analysis have been applied to distinguish between aromatic and non-aromatic rice. Diversity for some traits of agronomic importance, such as plant height was detected among countries, e.g. Afghan cultivars classified as tall, and Iranian and Uzbek intermediate and short, respectively. Differentiations of panicle, grain, leaf, basal internode, and culm dimension among rice cultivars, indicating the source of rice diversity in Central Asia. According to the results, 6 of 10, 2 of 7, and 0 of 6 of Afghan, Iranian, and Uzbek rice cultivars were scored as aromatic, respectively. Therefore, Afghan cultivars are a good source of aromatic rice germplasm for Central Asia. The expression between aromatic and non-aromatic, and aromatic and aromatic combinations has been evaluated. The observed segregation ratio of these crosses in the $F_2$ populations was tested by $x^2$ analysis against the expected ratio for a single gene. A segregation ratio of 3:1 between non-aromatic and aromatic combination has been detected, while segregation has not been detected between the aromatic and aromatic combinations. Also, parallel results were obtained from the tested aromatic rice cultivars. Thus, our results suggest that a single recessive gene controls aroma in all aromatic rice cultivars.