• Title/Summary/Keyword: Comparative clinical study

Search Result 879, Processing Time 0.031 seconds

Development of Novel Dental Chews for Dogs Considering Breed Variations in Anatomical Features of Dentition

  • Noh, Hyun-woo;Kang, Seon-mi;Seo, Kangmoon
    • Journal of Veterinary Clinics
    • /
    • v.34 no.6
    • /
    • pp.429-433
    • /
    • 2017
  • The purpose of this study was to find anatomical variation of each small breed dog's dentition for designing more effective dental chews. Small breed dogs were volunteered for dental impressions with dental stone and alginate under tiletamine-zolazepam, tramadol, and medetomidine intravenous anesthesia. Twenty-two criteria were measured to compare dental impressions. Twenty-five dogs (9 Malteses, 8 Miniature Poodles, and 8 Shih-Tzus) were recruited. Statistically, Shih-Tzus had smaller teeth and shorter interdental spaces than those of Maltese and Miniature Poodles. Grossly, the distance between upper teeth and lower teeth was wider in Shih-Tzus. Shih-Tzu had different dental anatomy in comparative to Miniature Poodle and Maltese. It was recommended to design the dental chew considering these differences.

Hemodynamically Isolated Intracranial Aneurysms on DSA and CEMRA: Clinical and Experimental Data

  • 정태섭;강원석;심용운;임윤철;이승구;주진양
    • Proceedings of the KSMRM Conference
    • /
    • 2001.11a
    • /
    • pp.134-134
    • /
    • 2001
  • Purpose: To evaluate the physiologic background of poorly visualized aneurysms during DSA a contrast-enhanced MRA(CEMRA) due to hemodynamical isolation on clinical and experiment data. Method: Two cases of intracranial aneurysm which were poorly visualized on DSA a CEMRA and one case of intracranial aneurysm which had poor turnover of contrast mediu during DSA were selected for this clinical study. We evaluated the turnover of blood in t terminal aneurysm of handmade elastic silicon phantoms for comparative experiment. Flo experiments with DSA and contrast enhanced MRA were performed in elastic phantoms aneurysm with 3 different diameters (2, 5 and 10 mm) of neck mimicking basilar ti aneurysm, attached to pulsatile pump similar to that of human physiologic parameters. W compared the results with those of computational flow dynamics(CFD).

  • PDF

Effect of HWANGRYUNHAEDOKTANG herd-acupuncture on functional headache (황연해독탕약침(黃連解毒湯藥針)의 기능성두통(機能性頭痛) 치료(治療) 효과(效果)에 대한 임상적(臨床的) 고찰(考察))

  • Choi, Eun-Gyu;Gu, Byung-Su
    • Journal of Oriental Neuropsychiatry
    • /
    • v.11 no.1
    • /
    • pp.75-81
    • /
    • 2000
  • A clinical analysis was carried out for 37 patients who was treated for functional headache with HWANGRYUNHAEDOKTANG(黃連解毒湯) herb-acupuncture in Seoul Red-Cross Oriental Hospital. The results were as follows; 1. The effect of HWANGRYUNHAEDOKTANG(黃連解毒湯) herb-acupuncture for functional headache was turned out to be better effective the young and middle age than the old. 2. Man was better effective than woman 3. There were effective at tention headache and migraine. 4. There were effective within 6 monthes from onset. 5. There were availability in according with increasing treatment. Through the clinical consequences of therapy mentioned above, we came to confirm regular therapeutic effects for functional headache and hereafter, it is considered that a clinical comparative study on oriental cure and herb-acupuncture therapy for headache has to be more progressed than now.

  • PDF

THE CLINICAL EVALUATION OF POTASSIUM NITRATE DENTIFRICE FOR DENTINAL HYPERSENSITIVITY (상아질 지각과민증에 대한 Potassium Nitrate 치약의 임상적 평가)

  • Han, Soo-Boo;Park, Sang-Hyun;Moon, Hyock-Soo
    • Journal of Periodontal and Implant Science
    • /
    • v.24 no.1
    • /
    • pp.196-204
    • /
    • 1994
  • The purpose of this clinical trial was to study the effectiveness of 5% potassium nitrate dentifrice as a daily home treatment of dentinal hypersensitivity. Thirty subjects with dentinal hypersensitivity were included in a 4-week, double-blind, parallel, comparative study. Stimuli used included mechanical, cold water and compressed air blasts. A subjective assessment of the degree of hypersensitivity for each stimulus was recorded. The results indicated that 5% potassium nitrate dentifrice, in comparision with a conventional fluoride dentifrice, reduced dentinal hypersensitivity to a significant degree. The therapeutic response to potassium nitrate was apparent within 2 weeks and increased continuously for the length of the study period. We conclude that 5% potassium nitrate dentifrice is an effective agent for the daily home treatment of dentinal hypersensitivity.

  • PDF

A Comparative Study of Restricted Randomization Methods in Clinicla Trials

  • Huh, Myung-Hoe
    • Journal of the Korean Statistical Society
    • /
    • v.14 no.1
    • /
    • pp.48-55
    • /
    • 1985
  • In clinical trials subjects are avalible sequentially and must be assigned to treatments immediately. Completely randomized procedure for the allocation of treatments to each subject may result in severe imbalance among the number of subjects in treatment groups, especially for small experiments or interim analyses of large experiments. In this study, restricted randomization methods such as biased coin designs (Efron, 1971), permuted block design, and truncated binomial design are compared to teh completely randomized design in the presence of selection and/or accidential bias by Monte Carlo simulations.

  • PDF

Clinical study of pulmonary resection using stapling device (Stapler 를 사용한 폐절제술에 대한 임상적 고찰)

  • 곽영태
    • Journal of Chest Surgery
    • /
    • v.16 no.2
    • /
    • pp.251-254
    • /
    • 1983
  • A comparative study was taken for pulmonary resection between group stapler used and not used. 1 ] There was no bronchopleural fistula in 22 cases of stapler used group, but in 4.5% in not used group. 2] The postoperative amount of fluid and air leakage through the chest tube were lesser in stapler used group. 3] The operating time was shorter in stapler used group because of lesser dissection of hilar structure.

  • PDF

1p36 deletion syndrome confirmed by fluorescence in situ hybridization and array-comparative genomic hybridization analysis

  • Kang, Dong Soo;Shin, Eunsim;Yu, Jeesuk
    • Clinical and Experimental Pediatrics
    • /
    • v.59 no.sup1
    • /
    • pp.14-18
    • /
    • 2016
  • Pediatric epilepsy can be caused by various conditions, including specific syndromes. 1p36 deletion syndrome is reported in 1 in 5,000-10,000 newborns, and its characteristic clinical features include developmental delay, mental retardation, hypotonia, congenital heart defects, seizure, and facial dysmorphism. However, detection of the terminal deletion in chromosome 1p by conventional G-banded karyotyping is difficult. Here we present a case of epilepsy with profound developmental delay and characteristic phenotypes. A 7-year-and 6-month-old boy experienced afebrile generalized seizure at the age of 5 years and 3 months. He had recurrent febrile seizures since 12 months of age and showed severe global developmental delay, remarkable hypotonia, short stature, and dysmorphic features such as microcephaly; small, low-set ears; dark, straight eyebrows; deep-set eyes; flat nasal bridge; midface hypoplasia; and a small, pointed chin. Previous diagnostic work-up, including conventional chromosomal analysis, revealed no definite causes. However, array-comparative genomic hybridization analysis revealed 1p36 deletion syndrome with a 9.15-Mb copy loss of the 1p36.33-1p36.22 region, and fluorescence in situ hybridization analysis (FISH) confirmed this diagnosis. This case highlights the need to consider detailed chromosomal study for patients with delayed development and epilepsy. Furthermore, 1p36 deletion syndrome should be considered for patients presenting seizure and moderate-to-severe developmental delay, particularly if the patient exhibits dysmorphic features, short stature, and hypotonia.

Comparative observational study of aminophylline with prophylactic and therapeutic uses for clinical outcomes in preterm infants

  • Bae, Mi Hye;Lee, Na Rae;Han, Young Mi;Byun, Shin Yun;Park, Kyung Hee
    • Kosin Medical Journal
    • /
    • v.33 no.3
    • /
    • pp.380-385
    • /
    • 2018
  • Objectives: Aminophylline has been used for prevention or treatment of apnea in preterm infants with idiopathic apnea of prematurity. The aim of this study was to assess the clinical usefulness of prophylactic in comparison with therapeutic aminophylline therapy. Methods: This retrospective observational study included infants born with a birth weight of < 2,500 g or at < 36 weeks of gestation. Infants born between August 2013 and July 2014 who received aminophylline therapy within 24 hr after birth were assigned to the prophylactic group, while infants born between August 2014 and July 2015 who received aminophylline therapy after obvious apnea were assigned to the therapeutic group. We compared clinical characteristics, including days of ventilator and oxygen therapy and bronchopulmonary dysplasia (BPD) between both groups. Results: Sixty-four patients and 25 infants were identified in the prophylactic and therapeutic groups, respectively. The mean gestational age and birth weight were $32.57{\pm}1.96weeks$ and $1765{\pm}205g$, respectively, in the prophylactic group and $32.46{\pm}1.82weeks$ and $1770{\pm}250g$, respectively, in the therapeutic group. No significant differences in clinical characteristics were found between the two groups. Similar clinical outcomes, including days of ventilator and oxygen therapy, intraventricular hemorrhage (IVH), periventricular leukomalacia, and BPD, were observed between the two groups. Conclusions: The present study showed that the prophylactic use of aminophylline does not improve the clinical outcomes, including BPD, IVH, and ventilator dependency as compared with therapeutic use. In other words, routine prophylactic use of aminophylline is unnecessary.

Factors Affecting Clinical Practicum Stress of Nursing Students: Using the Lazarus and Folkman's Stress-Coping Model (간호대학생의 임상실습 스트레스 영향요인에 관한 경로분석: Lazarus와 Folkman의 스트레스-대처 모델 기반으로)

  • Kim, Sung Hae;Lee, JuHee;Jang, MiRa
    • Journal of Korean Academy of Nursing
    • /
    • v.49 no.4
    • /
    • pp.437-448
    • /
    • 2019
  • Purpose: This study was conducted to test a path model for the factors related to undergraduate nursing students' clinical practicum stress, based on Lazarus and Folkman's stress-coping model. Methods: This study utilized a path analysis design. A total of 235 undergraduate nursing students participated in this study. The variables in the hypothetical path model consisted of clinical practicum, emotional intelligence, self-efficacy, Nun-chi, and nursing professionalism. We tested the fit of the hypothetical path model using SPSS/WIN 23.0 and AMOS 22.0. Results: The final model fit demonstrated a satisfactory statistical acceptance level: goodness-of-fit-index=.98, adjusted goodness-of-fit-index=.91, comparative fit index=.98, normed fit index=.95, Tucker-Lewis index=.92, and root mean square error of approximation=.06. Self-efficacy (${\beta}=-.22$, p=.003) and Nun-chi behavior (${\beta}=-.17$, p=.024) were reported as significant factors affecting clinical practicum stress, explaining 10.2% of the variance. Nursing professionalism (${\beta}=.20$, p=.006) and self-efficacy (${\beta}=.45$, p<.001) had direct effects on emotional intelligence, explaining 45.9% of the variance. Self-efficacy had indirect effects on Nun-chi understanding (${\beta}=.20$, p<.001) and Nun-chi behavior (${\beta}=.09$, p=.005) through emotional intelligence. Nursing professionalism had indirect effects on Nun-chi understanding (${\beta}=.09$, p=.005) and Nun-chi behavior (${\beta}=.09$, p=.005) through emotional intelligence. The variables for self-efficacy and nursing professionalism explained 29.1% of the Nun-chi understanding and 18.2% of the Nun-chi behavior, respectively. Conclusion: In undergraduate nursing education, it is important to identify and manage factors that affect clinical practicum stress. The findings of this study emphasize the importance of Nun-chi, self-efficacy, emotional intelligence, and nursing professionalism in the development of an educational strategy for undergraduate nursing students.

A Qualitative Study for the Development of the Assessment Model for Korean Resonance Disorders (공명장애 진단모델 개발을 위한 질적 연구)

  • Han, Jin-Soon;Sim, Hyun-Sub
    • Speech Sciences
    • /
    • v.13 no.4
    • /
    • pp.157-173
    • /
    • 2006
  • Speech-language therapist's experiences of their clinical practice offer greater insight to develop the assessment model for resonance disorders appropriate to the clinical setting. In order to investigate their experiences of resonance disorders qualitatively, a semi-structured interview questionnaire was developed on the basis of the review of the literatures about the assessment procedures. From the interviews with 4 speech therapists analysed by using a qualitative, constant-comparative method, 3 main themes were derived: (1) the currently accepted definitions and characteristics of the resonance disorders, (2) the status quo of the assessment procedures, and (3) the needs for the improvement of the assessment procedures. In addition, 15 sub-themes were emerged from the 3 main themes. All themes mentioned by the therapists provide the directions for the development of comprehensive and valid assessment model for the resonance disorders in Korea.

  • PDF