• 한국농공학회논문집
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• 제60권6호
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• pp.111-119
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• 2018

The air-void is known to be one of the influencing factors for estimating long-term performance of asphalt concrete. Most of all, confirming air void or density of pavement layer is important for quality control of field compaction level of asphalt concrete pavement. In this study, a non-nuclear type non-destructive density gage (NDDG) was used to estimate compacted air-voids of asphalt pavement as a non-destructive test method. Asphalt concrete slab specimens were prepared using 6 types of asphalt mixes in laboratory (lab) for lab NDDG test. Four different base structure materials were used to find out if there were any differences due to the type of base structure materials. The actual air-voids and NDDG air-voids were measured from 6 asphalt concrete slabs. Four sections of field asphalt pavements were tested using the NDDG, and actual air voids were also measured from field cores taken from the site where the NDDG air-void was measured. From lab and field experimental tests, it was found that the air-voids obtained by NDDG were not the same as the actual air-voids measured from the asphalt concrete specimen. However, it was possible to estimate air voids based on the relationship obtained from regression analysis between actual and NDDG air voids. The predicted air-voids based on the NDDG air-voids obtained from 50mm depth were found to be reliable levels with $R^2{\fallingdotseq}0.9$. Therefore, it was concluded that the air-voids obtained from NDDG could be used to estimate actual air-voids in the field asphalt pavement with a relatively high coefficient of determination.

• 아시안잔디학회지
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• 제16권1호
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• pp.19-30
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• 2002

경직된 지반의 물리성 개선재로서 rubber chip의 토양 내 혼합 또는 배토는 잔디의 생육과 지반의 이·화학성 및 중금속 추출 실험을 통하여 다음과 같은 결론을 얻었다. Rubber chip의 토양 내 혼합은 지면의 온도 상승효과를 가져왔으며 이는 겨울철의 동해방지 및 맹아출현기를 앞당길 수 있을 것이라 추정된다. 그러나 복사열이 높은 여름에는 rubber chip에 의한 표면, 지중 온도의 상승으로 잔디의 피해가 우려된다. 또한 토양 내에 rubber chip의 혼합함량(rubber chip 20%, 40%)이 많을수록 잔디의 발아와 생육 및 피복에 부정적인 영향을 끼쳤다. Rubberchip의 토양혼합은 지반의 이·화학성 변화에 크게 작용하지 않았으며 중금속 추출실험에서도 차이를 나타내지 않아 토양환경 오염이 없을 것으로 판단된다. Rubber chip을 배토용 재료로서 사용했을 경우, 경직된 토양구조를 개선시켜 주었다. 특히 통기작업 후 rubber chip의 배토는 지반의 표면탄성을 현저히 완화시켰다. 따라서 현재 우리나라에서 보수중이 거나 건설중인 연습구장, 보조구장에 재활용이 가능한 폐타이어 rubber chip을 지반 답압 개선용, 배토용 재료로서 사용이 가능할 것으로 판단된다.

• 한국지반공학회논문집
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• 제32권4호
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• pp.51-61
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• 2016

본 연구는 최근 국내 외로 지반공학적 특성 평가 연구가 진행되고 있는 TDR(Time Domain Reflectometry)을 개선하기 위하여 진행되었고, 이를 통해 $30.48cm{\times}25.4cm$의 크기를 갖는 판형 Probe를 제작하였다. 개발한 TDR 시스템을 검증하기 위하여 주문진 표준사 및 세 종류의 일반적인 시료를 대상으로 실내실험을 실시하였다. TDR 신호를 이용하여 흙의 유전상수, 전기전도도, 특성상수 값을 도출하였다. 이를 통해 흙의 함수비 및 건조밀도를 구하였고, 실제 측정한 값과의 비교를 통하여 개발 TDR의 적용성을 검토하였다. 실험 결과, 건조밀도의 경우 평균적으로 약 2%의 오차를 보이며, 함수비의 경우 평균적으로 약 0.5%의 오차를 보이는 것을 확인할 수 있었다. 실험 결과를 통하여 기존의 TDR시스템을 사용하였을 때 발생할 수 있는 문제점과 측정할 때 소요되는 시간 등을 줄일 수 있을 것으로 판단된다.

• 한국지반공학회논문집
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• 제19권4호
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• pp.15-21
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• 2003

본 연구는 풍화 화강토의 일정 간극비에서 초기함수비의 변화에 따른 거동 특성을 통상의 삼축압축시험기를 이용한 비배수시험을 실시하여 비배수전단시 불포화 풍화 화강토의 간극압, 체적변형 및 응력-변형률 거동특성을 밝히고자한다. 연구에 사용된 시료는 조립질의 풍화 화강토이고 직경 50mm 높이 100mm로 복층다짐하여 삼축 시험용 공시체를 제작하였다. 준비된 공시체를 구속압력과 흡인력($u_a-u_w$)을 각각 달리한 비배수 3축압축시험을 실시하였다. 그 결과 초기 함수비의 변화에 따라 내부마찰각($\phi'$)의 변화는 다소 있지만 흡인력의 변화에 따른 내부마찰각의 변화는 거의없고 유효점착력만이 증가하는 경향을 보이고 있다.

• 공업화학
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• 제10권2호
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• pp.201-205
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• 1999

Hydroxypropylmethylcelluloses (HPMC)는 친수성 cellulose 계통의 중합체로서 독성이 적고 가격이 저렴하여 경구용 서방출성 제제에 널리 이용되고 있다. 본 연구에서는 매트릭스로서 HPMC를 이용하여 새로운 서방출성제제인 HPMC/염산슈도에페드린계를 설계하고, 직타법에 의하여 정제를 제조하였으며, 이 팽윤될 수 있는 친수성 약물전달계를 이용하여 약물의 방출에 영향을 주는 여러 인자들이 약물의 방출속도에 미치는 영향에 대하여 조사하였다. 결과로서, HPMC/염산슈도에페드린계에서 매트릭스인 HPMC의 분자량이 클수록, HPMC의 함량이 많을수록 약물의 방출속도가 더 느려짐을 알 수 있었으며, 정제의 경도나 용출시 pH 변화에는 무관한 것으로 나타났다. 특히, 음이온 계면활성제인 sodium laurylsulfate는 HPMC로부터 염산슈도에페드린의 방출속도를 지연시키는데 큰 영향을 미치는 것으로 나타났으며, 이러한 현상은 음이온 계면활성제인 sodium laurylsulfate가 반대의 이온성을 갖는 약물인 염산슈도에페드린과 착물을 형성함으로써 약물의 용해성이 떨어져서 약물방출이 지연되는 것으로 생각된다.

• 한국지반공학회:학술대회논문집
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• 한국지반공학회 2008년도 추계 학술발표회
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• pp.1532-1548
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• 2008

The tunnel type spillways is under construction to increasing water reservoir capacity in Dae-am dam. The tunnel outlet was planned to be made after installing slope stabilization system on natural slope there. Generally, the tunnel outlet is made perpendicularly to the slope, but in this case, it had to be made obliquely to the slope for not interrupting flow of river. Because of excavation in condition of natural slope caused to deflecting earth pressure, the outlet couldn't be made. So, artificial ground made with concrete that it was constructed in the outside of tunnel for producing the arching effect which enables to make a outlet. We were planned tunnel excavation was carried out after artificial ground made. Artificial ground made by poor mix concrete of which it was planned that the thickness was at least 3.0m height from outside of tunnel lining and 30cm of height per pouring. Spreading and compaction was planned utilized weight of 15 ton roller machine. In order to access of working truck, slope of artificial ground was designed 1:1.0 and applied 2% slope in upper pert of it for easily drainage of water. In addition to, upper pert of artificial ground was covered with soil, because of impaction of rock fall from upper slope was made minimum. The tunnel excavation of the artificial ground was designed application with special blasting method that it was Super Wedge and control blasting utilized with pre-percussion hole.

• 한국지반공학회논문집
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• 제18권5호
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• pp.109-122
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• 2002

지표부근의 지반의 경우, 함수비가 지반의 동적 물성치에 큰 영향을 주는 요소가 된다. 본 연구에서는 함수비의 변화 때문에 발생하는 최대전단탄성계수, 전단탄성계수 감소곡선, 감쇠비의 전반적인 변화를 공진주/비틂전단 시험을 통해 평가했다. 기존의 동적물성치에 대한 다짐함수비의 영향 연구와는 달리 일정한 다짐함수비로 성형된 시료에 대하여 모관흡수력(capillary pressure)을 조절하는 방법으로 함수비를 변화시키고 이때의 동적물성치의 변화를 평가하였다. 이를 위하여 기존의 공진주/비틀전단시험 시스템을 개량하여 함수비 변화뿐만 아니라 모관흡수력의 변화에 따른 동적물성치의 변화도 함께 평가할 수 있도록 하였다. 또한 실내에서 공진주/비틂전단 시험으로 결정된 함수비에 따른 전단탄성계수의 변화 양상을 동일현장(한국도로공사 시험도로)에서 수행된 크로스흘 시험결과와 비교하여 그 타당성을 검증하였으며, 현장으로의 확장 가능성을 확인하였다. 실내시험과 현장시험으로부터 구한 전단탄성계수는 합리적인 범위에서 일치하였으며, 함수비가 감소함에 따라 증가하는 경향을 나타내었다.

• Geomechanics and Engineering
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• 제19권1호
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• pp.37-47
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• 2019

The main objective of this study is to evaluate and compare the efficiency of ordinary Portland cement (OPC) in enhancing the unconfined compressive strength of soft soil alone and soft soil mixed with recycled tiles. The recycled tiles have been used to treat soft soil in a previous research by Al-Bared et al. (2019) and the results showed significant improvement, but the improved strength value was for samples treated with low cement content (2%). Hence, OPC is added alone in this research in various proportions and together with the optimum value of recycled tiles in order to investigate the improvement in the strength. The results of the compaction tests of the soft soil treated with recycled tiles and 2, 4, and 6% OPC revealed an increment in the maximum dry density and a decrement in the optimum moisture content. The optimum value of OPC was found to be 6%, at which the strength was the highest for both samples treated with OPC alone and samples treated with OPC and 20% recycled tiles. Under similar curing time, the strength of samples treated with recycled tiles and OPC was higher than the treated soil with the same percentage of OPC alone. The stress-strain curves showed ductile plastic behaviour for the untreated soft clay and brittle behaviour for almost all treated samples with OPC alone and OPC with recycled tiles. The microstructural tests indicated the formation of new cementitious products that were responsible for the improvement of the strength, such as calcium aluminium silicate hydrate. This research promotes recycled tiles as a green stabiliser for soil stabilisation capable of reducing the amount of OPC required for ground improvement. The replacement of OPC with recycled tiles resulted in higher strength compared to the control mix and this achievement may results in reducing both OPC in soil stabilisation and the disposal of recycled tiles into landfills.

• 한국동물생명공학회지
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• 제37권3호
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• pp.183-192
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• 2022

Lipopolysaccharide (LPS) is an endotoxin factor present in the cell wall of Gram-negative bacteria and induces various immune responses to infection. Recent studies have reported that LPS induces cellular stress in various cells including oocytes and embryos. Melatonin (N-acetyl-5-methoxytryptamine) is a regulatory hormone of circadian rhythm and a powerful antioxidant. It has been known that melatonin has an effective function in scavenging oxygen free radicals and has been used as an antioxidant to reduce the cytotoxic effects induced by LPS. However, the effect of melatonin on LPS treated early embryonic development has not yet been confirmed. In this study, we cultured mouse embryos in medium supplemented with LPS or/and melatonin up to the blastocyst stage in vitro and then evaluated the developmental rate. As a result of the LPS-treatment, the rate of blastocyst development was significantly reduced compared to the control group in all the LPS groups. Next, in the melatonin only treated group, there was no statistical difference in embryonic development and no toxic effects were observed. And then we found that the treatment of melatonin improved the rates of compaction and blastocyst development of LPS-treated embryos. In addition, we showed that melatonin treatment decreased ROS levels compared to the LPS only treated group. In conclusion, we demonstrated the protective effect of melatonin on the embryonic developmental rate reduced by LPS. These results suggest a direction to improve reproduction loss that may occur due to LPS exposure and bacterial infection through the using of melatonin during in vitro culture.

• 한국동물생명공학회지
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• 제37권2호
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• pp.121-129
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• 2022

Heterogeneous nuclear ribonucleoprotein A2/B1 (hnRNPA2/B1) is an N6-methyladenosine (m⁶A) RNA modification regulator and a key determinant of prem-RNA processing, mRNA metabolism and transportation in cells. Currently, m⁶A reader proteins such as hnRNPA2/B1 and YTHDF2 has functional roles in mice embryo. However, the role of hnRNPA2/B1 in porcine embryogenic development are unclear. Here, we investigated the developmental competence and mRNA expression levels in porcine parthenogenetic embryos after hnRNPA2/B1 knock-down. HhnRNPA2/B1 was localized in the nucleus during subsequent embryonic development since zygote stage. After hnRNPA2/B1 knock-down using double stranded RNA injection, blastocyst formation rate decreased than that in the control group. Moreover, hnRNPA2/B1 knock-down embryos show developmental delay after compaction. In blastocyste stage, total cell number was decreased. Interestingly, gene expression patterns revealed that transcription of Pou5f1, Sox2, TRFP2C, Cdx2 and PARD6B decreased without changing the junction protein, ZO1, OCLN, and CDH1. Thus, hnRNPA2/B1 is necessary for porcine early embryo development by regulating gene expression through epigenetic RNA modification.