• The Journal of the Convergence on Culture Technology
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• v.9 no.5
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• pp.897-907
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• 2023

The purpose of this study is to find out the development direction of adult learners' blended learning class as a study on the class satisfaction of adult college students according to the blended learning class participation type. To this end, a survey was conducted targeting adult learners at two schools that are carrying out the LiFE project (lifelong education system support project). The analyzed research results are as follows. First, in the case of adult learners, the proportion of participating in liberal arts + major classes as a blended learning subject was 77.8%, and home was the highest with 69.8% as a place to participate in online classes. Second, satisfaction with the blended learning teacher/instructor teaching method was generally satisfied with 95.2% of average or higher. Third, 96.8% of the students answered 'yes' or higher regarding the level of satisfaction with the blended learning method. The above research results show that blended learning is one of the important teaching and learning methods in providing adult-tailored education to adult learners who combine work and study. It can be seen that the blended learning teaching method is an effective teaching method that enables interactive communication between the instructor and the learner rather than the one-way teaching-oriented content delivery class of the traditional classroom.

• Journal of the Korean Geotechnical Society
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• v.39 no.12
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• pp.61-73
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• 2023

Suction buckets are feasible options for offshore foundations to support subsea structures in deep water, enabling suction-induced installation by pumps. Recently, hybrid suction bucket foundations that combine single or multiple suction buckets with a mat foundation have been considered. The foundations effectively increase the load capacity while reducing construction costs. However, there is still insufficient experimental validation of hybrid suction bucket foundations regarding their bearing capacity. Furthermore, research on the horizontal load capacity under low vertical and moment loads is inadequate. In this study, we investigate the feasibility of using a hybrid suction bucket foundation for subsea installations in clay. We considered two types of hybrid suction bucket foundations: a circular mat with a single suction bucket and a square mat with multiple buckets. Centrifuge tests were performed to understand the hybrid suction bucket foundation characteristics under horizontal loads and their corresponding bearing capacity. Particularly, we verified the effect of the mat foundation and bucket embedment depth on the horizontal bearing mechanism and capacities. Results confirmed that the hybrid suction bucket foundation outperforms the single suction bucket.

• Korean Journal of Radiology
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• v.22 no.9
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• pp.1451-1461
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• 2021

Objective: Adequate methods of combining T2-weighted imaging (T2WI) and diffusion-weighted imaging (DWI) to assess complete response (CR) to chemoradiotherapy (CRT) for rectal cancer are obscure. We aimed to determine an algorithm for combining T2WI and DWI to optimally suggest CR on MRI using visual assessment. Materials and Methods: We included 376 patients (male:female, 256:120; mean age ± standard deviation, 59.7 ± 11.1 years) who had undergone long-course CRT for rectal cancer and both pre- and post-CRT high-resolution rectal MRI during 2017-2018. Two experienced radiologists independently evaluated whether a tumor signal was absent, representing CR, on both post-CRT T2WI and DWI, and whether the pre-treatment DWI showed homogeneous hyperintensity throughout the lesion. Algorithms for combining T2WI and DWI were as follows: 'AND,' if both showed CR; 'OR,' if any one showed CR; and 'conditional OR,' if T2WI showed CR or DWI showed CR after the pre-treatment DWI showed homogeneous hyperintensity. Their efficacies for diagnosing pathologic CR (pCR) were determined in comparison with T2WI alone. Results: Sixty-nine patients (18.4%) had pCR. AND had a lower sensitivity without statistical significance (vs. 62.3% [43/69]; 59.4% [41/69], p = 0.500) and a significantly higher specificity (vs. 87.0% [267/307]; 90.2% [277/307], p = 0.002) than those of T2WI. Both OR and conditional OR combinations resulted in a large increase in sensitivity (vs. 62.3% [43/69]; 81.2% [56/69], p < 0.001; and 73.9% [51/69], p = 0.008, respectively) and a large decrease in specificity (vs. 87.0% [267/307]; 57.0% [175/307], p < 0.001; and 69.1% [212/307], p < 0.001, respectively) as compared with T2WI, ultimately creating additional false interpretations of CR more frequently than additional identification of patients with pCR. Conclusion: AND combination of T2WI and DWI is an appropriate strategy for suggesting CR using visual assessment of MRI after CRT for rectal cancer.

• Journal of the Korea Society of Computer and Information
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• v.29 no.3
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• pp.217-225
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• 2024

To foster the core talents of the future, the development of diverse and substantial SW·AI education programs is required, and a systematic system that can assist public education in SW and AI must be established. In this study, we develop and combine SW·AI education modules to construct a SW and AI education program applicable to public education. We also establish a systematic education system and provide sustainable SW·AI education to elementary, middle, and high school students through 'Job's Garage Camp' based on various sharing platforms. By creating a sustainable follow-up educational environment, students are encouraged to continue their self-directed learning of SW and AI. As a result of conducting a pre-post survey of students participating in the 'Job's Garage Camp', the post-survey values improved compared to the pre-survey values in all areas of 'interest', 'understanding and confidence', and 'career aspirations'. Based on these results, it can be confirmed that students had a universal positive perception and influence on SW and AI. Therefore, if the operation case of 'Job's Garage Camp' is improved and expanded, it can be presented as a standard model applicable to other SW and AI education programs in the future.

• Korean Journal of Radiology
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• v.21 no.7
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• pp.812-828
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• 2020

Objective: To provide an evidence-based guide for the MRI interpretation of complete tumor response after neoadjuvant chemoradiation therapy (CRT) for rectal cancer using visual assessment on T2-weighted imaging (T2) and diffusion-weighted imaging (DWI). Materials and Methods: PubMed MEDLINE, EMBASE, and Cochrane Library were searched on November 28, 2019 to identify articles on the following issues: 1) sensitivity and specificity of T2 or DWI for diagnosing pathologic complete response (pCR) and the criteria for MRI diagnosis; 2) MRI alone vs. MRI combined with other test(s) in sensitivity and specificity for pCR; and 3) tests to select patients for the watch-and-wait management. Eligible articles were selected according to meticulous criteria and were synthesized. Results: Of 1615 article candidates, 55 eligible articles (for all three issues combined) were identified. Combined T2 and DWI performed better than T2 alone, with a meta-analytic summary sensitivity of 0.62 (95% confidence interval [CI], 0.43-0.77; I² = 80.60) and summary specificity of 0.89 (95% CI, 0.80-0.94; I² = 92.61) for diagnosing pCR. The criteria for the complete response on T2 in most studies had the commonality of remarkable tumor decrease to the absence of mass-like or nodular intermediate signal, although somewhat varied, as follows: (near) normalization of the wall; regular, thin, hypointense scar in the luminal side with (near) normal-appearance or homogeneous intermediate signal in the underlying wall; and hypointense thickening of the wall. The criteria on DWI were the absence of a hyperintense signal at high b-value (≥ 800 sec/mm²) in most studies. The specific algorithm to combine T2 and DWI was obscure in half of the studies. MRI combined with endoscopy was the most utilized means to select patients for the watch-and-wait management despite a lack of strong evidence to guide and support a multi-test approach. Conclusion: This systematic review and meta-analysis provide an evidence-based practical guide for MRI assessment of complete tumor response after CRT for rectal cancer.

• Journal of Korea Water Resources Association
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• v.57 no.2
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• pp.73-85
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• 2024

Predicting water quality of rivers and reservoirs is necessary for the management of water resources. Artificial Neural Networks (ANNs) have been used in many studies to predict water quality with high accuracy. Previous studies have used Gradient Descent (GD)-based optimizers as an optimizer, an operator of ANN that searches parameters. However, GD-based optimizers have the disadvantages of the possibility of local optimal convergence and absence of a solution storage and comparison structure. This study developed improved optimizers to overcome the disadvantages of GD-based optimizers. Proposed optimizers are optimizers that combine adaptive moments (Adam) and Nesterov-accelerated adaptive moments (Nadam), which have low learning errors among GD-based optimizers, with Harmony Search (HS) or Novel Self-adaptive Harmony Search (NSHS). To evaluate the performance of Long Short-Term Memory (LSTM) using improved optimizers, the water quality data from the Dasan water quality monitoring station were used for training and prediction. Comparing the learning results, Mean Squared Error (MSE) of LSTM using Nadam combined with NSHS (NadamNSHS) was the lowest at 0.002921. In addition, the prediction rankings according to MSE and R² for the four water quality indices for each optimizer were compared. Comparing the average of ranking for each optimizer, it was confirmed that LSTM using NadamNSHS was the highest at 2.25.

• Journal of the Korea institute for structural maintenance and inspection
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• v.10 no.3
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• pp.165-175
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• 2006

To analyze the deformation and failure of slopes, generally, two types of model, Polynomial model and Growth model, are applied. These two models are focused on the behavior of the slope by time. Therefore, this research is more focused on predicting of slope failure than analyzing the slope behavior by time. Generally, Growth model is used to analyze the soil slope, to the contrary, Polynomial model is used for rock slope. However, 3-degree polynomial($y=ax^3+bx^2+cx+d$) is suggested to combine two models in this research. The main trait of this model is having an asymptote. The fields to adopt this model are Gosujae Danyang(soil slope) and Youngduk slope(rock slope), which are the cut-slope near national road. Data from Gosujae are shown the failure traits of soil slope, to the contrary, those of Youngduk slope are shown the traits of rock slope. From the real-time monitoring data of the slope, 3-degree polynomial is proved as excellent system to analyze the failure and behavior of slope. In case of Polynomial model, even if the order of polynomials is increased, the $R^2$ value and shape of the curve-fitted graph is almost the same.

• International Journal of Stem Cells
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• v.15 no.3
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• pp.324-333
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• 2022

Background and Objectives: This study was to investigate the role of microRNA-29a-3p (miR-29a-3p) in human bone marrow mesenchymal stem cells (hBMSCs), and its relationship with steroid-associated osteonecrosis. Methods and Results: The online tool GEO2R was used to screen out the differentially expressed genes (DEGs) in GSE123568 dataset. Quantitative real time-polymerase chain reaction (qRT-PCR) was performed to detect the expression of miR-29a-3p, forkhead box O3 (FOXO3), alkaline phosphatase (ALP), bone gamma-carboxyglutamate protein (OCN) and RUNX family transcription factor 2 (Runx2) in the hBMSCs isolated from the patients with steroid-associated osteonecrosis. CCK-8 assay was executed to measure cell viability; western blot assay was utilized to detect FOXO3, ALP, Runx2, OCN and β-catenin expression. Cell apoptosis and cell cycle were detected by flow cytometry. Immunofluorescence assay was used to detect the sub-cellular localization of β-catenin. Bioinformatics analysis and luciferase reporter gene assay were performed to confirm whether miR-29a-3p can combine with FOXO3 3'UTR. MiR-29a-3p was markedly up-regulated in the hBMSCs of patients with steroid-associated osteonecrosis, while FOXO3 mRNA was significantly down-regulated. Transfection of miR-29a-3p mimics significantly inhibited the hBMSCs' proliferation, osteogenic differentiation markers' expressions, including ALP, Runx2, OCN, and repressed the ALP activity, as well as promoted cell apoptosis and cell-cycle arrest. FOXO3 was identified as a target gene of miR-29a-3p, and miR-29a-3p can inhibit the expression of FOXO3 and β-catenin, and inhibition of miR-29a-3p promoted translocation of β-catenin to the nucleus. Conclusions: MiR-29a-3p can modulate FOXO3 expression and Wnt/β-catenin signaling to inhibit viability and osteogenic differentiation of hBMSCs, thereby promoting the development of steroid-associated osteonecrosis.

• Journal of Dental Rehabilitation and Applied Science
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• v.40 no.3
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• pp.159-168
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• 2024

Through the use of intraoral scanners, it is possible to obtain intraoral scan impressions and produce prostheses. This approach is also being attempted not only in dentate patients but also in edentulous patients. However, obtaining scans of edentulous areas can be more challenging than scanning dental areas, and there may be limitations, especially in capturing the details of the mucosal tissues. On the other hand, when obtaining impressions with intraoral scanners, simultaneous recording of the occlusal relationship of the maxilla and mandible can reduce the number of patient visits and expedite the restoration process. In this case, we aimed to combine the advantages of direct intraoral scanning and indirect digital impressions obtained after traditional impression-taking by merging two types of scan files. Consequently, in patients with partially edentulous arches, we sought to provide effective interim prostheses through direct and indirect digital model impressions and report our findings accordingly.

• The Journal of the Convergence on Culture Technology
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• v.10 no.5
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• pp.77-82
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• 2024

The purpose of this study is to determine how satisfied adult learners are with school life when transitioning back to social life after obtaining a college degree, and to seek ways to improve education through analysis of future educational needs. Suggestions for the results are as follows. First, programs to improve adult learners' basic learning abilities must be continuously supported. As a result of the survey on satisfaction with the basic learning ability improvement program, 92% of respondents responded above average, so continued support for basic learning programs is required to help adult learners make up for their academic gap. Second, in the case of club activities and major certificate acquisition programs, the response rate was above average at 92%, indicating that students were overall satisfied with their school life. Third, there is a continued need for expanded application of classes that combine field practice in the subject area. Fourth, the development of liberal arts education subjects that reflect social needs is continuously required. Fifth, substantial operation of field experience programs is necessary. Junior colleges are higher education institutions that train experts. In order to cultivate practical talents who are closely related to the field after graduation, future field experience programs are required to be operated to help with major jobs.