• The Research Journal of the Costume Culture
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• v.27 no.5
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• pp.524-537
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• 2019

The aim of this study was to explore the effect of combinations of diverse methods notifying price discounts (i.e., reference price, odd price, and discount rate signs) and the relationships among product attribute perception, discount perception, attitude toward product, and purchase intention of product. Experiments were conducted where 12 stimuli of different price discount information notifications regarding T-shirt advertisements were presented to 352 informants. The results showed that notification of each type of discount information increased discount perception, whereas no effect due to the size of letters used in the discount rate notification was found. As more price discount information notifications were used, discount perception tended to become stronger. The results of ANOVA analysis show that both product attribute perception and discount perception affected attitude toward the product. In addition, product purchase intention was determined by attitude toward the product as well as price discount perception. Based on these findings, marketers may want to use a combination of methods of price discount notifications in advertisements to deliver price discount information clearly to consumers. Confirmation of discount information using multiple cues would help consumers to notice and perceive price discount information provided by retailers more effectively. Discount information is crucial for increasing both purchase intention and favorable attitude, therefore, diverse strategies regarding discount information presentations should be developed, tested and applied in the real world of retailing.

• Journal of Microbiology and Biotechnology
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• v.31 no.9
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• pp.1288-1294
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• 2021

There are a growing number of reports of hospital-acquired infections caused by pathogenic bacteria, especially methicillin-resistant Staphylococcus aureus (MRSA). Many plant products are now being used as a natural means of exploring antimicrobial agents against different types of human pathogenic bacteria. In this research, we sought to isolate and identify an active molecule from Sedum takesimense that has possible antibacterial activity against various clinical isolates of MRSA. NMR analysis revealed that the structure of the HPLC-purified compound was 1,2,4,6-tetra-O-galloyl-glucose. The minimum inhibitory concentration (MIC) of different extract fractions against numerous pathogenic bacteria was determined, and the actively purified compound has potent antibacterial activity against multidrug-resistant pathogenic bacteria, i.e., MRSA and its clinical isolates. In addition, the combination of the active compound and β-lactam antibiotics (e.g., oxacillin) demonstrated synergistic action against MRSA, with a fractional inhibitory concentration (FIC) index of 0.281. The current research revealed an alternative approach to combating pathogenesis caused by multi-drug resistant bacteria using plant materials. Furthermore, using a combination approach in which the active plant-derived compound is combined with antibiotics has proved to be a successful way of destroying pathogens synergistically.

• Advances in concrete construction
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• v.11 no.2
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• pp.163-171
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• 2021

This paper studies the effect of using multi-scale reinforcement additives on mechanical strengths, damage performance, microstructure, and water absorption of cementitious composites. Small dosages of carbon nanotubes (CNTs) or polypropylene (PP) microfibers; 0.05%, 0.1%, and 0.2% by weight of cement; were added either separately or simultaneously into cement mortar. The experimental results show the ability of these additives to enhance the mechanical behavior of the mortar. The best improvement in compressive and flexural strengths of cement mortar reaches 28% in the case of adding a combination of 0.1% CNTs and 0.2% PP fibers for compression, and a combination of 0.2% CNTs and 0.2% PP fibers for flexure. Adding CNTs does not change the brittle mode of failure of plain mortar whereas the presence of PP fibers changes it into ductile failure and clearly enhances the fracture energy of the specimens. Scanning electron microscopic (SEM) images of the fracture surfaces highlights the role of CNTs in improving the adhesion between the PP fibers and the hydration products and thus enhance the ability of the fibers to mitigate cracks propagation and to enhance the mechanical performance of the mortar.

• Journal of Dairy Science and Biotechnology
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• v.41 no.1
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• pp.1-8
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• 2023

Response surface methodology (RSM) is a statistical approach widely used in food processing to optimize the formulation, processing conditions, and quality of food products. The homogenization process is achieved by subjecting milk to high pressure, which breaks down fat globules and disperses fat more evenly throughout milk. This study focuses on an application of RSM including the logit transformation to predict the efficiency of milk homogenization, which can be maximized by minimizing the relative difference in fat percentage between the top part and the remainder of milk. To avoid a negative predicted value of the minimum of this proportion, the logit transformation is used to turn the proportion into the logit, whose possible values are real numbers. Then, the logit values are modeled and optimized. Subsequently, the logistic transformation is used to turn the predicted logit into the predicted proportion. From our model, the optimum condition for the maximized efficiency of milk homogenization was predicted as the combination of a homogenizer pressure of 30 MPa, a storage temperature of 10℃, and a storage period of 10 days. Additionally, with a combination of a homogenizer pressure of 30 MPa, a storage temperature of 10℃, and a storage period of 50 days, the level of milk homogenization was predicted to be acceptable, even with the problem of extrapolation taken into account.

• Journal of the Korean Wood Science and Technology
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• v.51 no.1
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• pp.49-57
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• 2023

This research aimed to evaluate the durability of Samama (Anthocephalus macrophyllus) wood treated with boron preservatives, citric acid (CA), and heating against termites. Wood samples were impregnated firstly with 5% boron solutions, such as boric acid, borax and boric acid + borax combination at 1:1 (w/w). The second impregnation used 5% CA. The impregnations were conducted in a pressure tank at 7 kg/cm² for 4 hours. After impregnation, the samples were heat treated at 80℃ or 160℃. All the treated and control samples were exposed to decay fungi, drywood termites and subterranean termites based on SNI 7207:2014 standard. The results showed that boron preservatives reduced fungal attacks on Samama wood. The combination treatment of boric acid, CA and heat treatment at 160℃ was also effective to increase the resistance of Samama wood against white- and brown rot fungi, and drywood termites. Heat treatment consistently improved the resistance of Samama wood from decay fungi.

• Nuclear Engineering and Technology
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• v.41 no.5
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• pp.729-738
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• 2009

Given the evolution of High-Temperature Gas-cooled Reactor(HTGR) designs, the source terms for licensing must be developed. There are three potential source terms: fission products, actinides in the fuel and tritium in the coolant. It is necessary to provide first an inventory of the source terms under normal operations. An analysis of source terms has yet to be performed for HTGRs. The previous code, which can estimate the inventory of the source terms for LWRs, cannot be used for HTGRs because the general data of a typical neutron cross-section and flux has not been developed. Thus, this paper uses a combination of the MCNP, ORIGEN, and MONTETEBURNS codes for an estimation of the source terms. A method in which the HTR-10 core is constructed using the unit lattice of a body-centered cubic is developed for core modeling. Based on this modeling method by MCNP, the generation of fission products, actinides and tritium with an increase in the burnup ratio is simulated. The model developed by MCNP appears feasible through a comparison with models developed in previous studies. Continuous fuel management is divided into five periods for the feeding and discharging of fuel pebbles. This discrete fuel management scheme is employed using the MONTEBURNS code. Finally, the work is investigated for 22 isotope fission products of nuclides, 22 actinides in the core, and tritium in the coolant. The activities are mainly distributed within the range of $10^{15}{\sim}10^{17}$ Bq in the equilibrium core of HTR-10. The results appear to be highly probable, and they would be informative when the spent fuel of HTGRs is taken into account. The tritium inventory in the primary coolant is also taken into account without a helium purification system. This article can lay a foundation for future work on analyses of source terms as a platform for safety assessment in HTGRs.

• The Journal of Korean Medicine
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• v.26 no.2 s.62
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• pp.152-165
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• 2005

Background: The use of herbal preparations as remedies for various medical conditions has continuously increased in Korea Large proportions of Korean patients use herbal medicinal products, folk remedies, and food supplements. However, studies on the safety of herbal products arc conducted on a less than sufficient basis even in the countries like Korea where herbal medicine is being used extensively. Some of the reports on the safety of herbs were done by the doctors of western medicine but lack of knowledge and misclassification led to misunderstandings. Objecitves: This study aims to review the recent evidences on hepatotoxic events associated with the use of herbal medicinal products, folk remedy, and food supplements. In the process, this review will grasp trends in this field of studies and will direct further researches into the right direction. Methods: Systematic literature searches were performed on MedRic and MEDLIS in Korea. Screening and selection of the articles and the extraction of data were performed independently by two of authors. There were no restrictions regarding the published date. In order to avoid bias, the articles written by medical doctors, not by oriental doctors were selected. 43 journals were chosen for the review. Results: Analyzing the number of journals, studies on the drug-induced liver injury were increased after the year 2000. The proportion of herbal and folk remedy associated hepatotoxic injuries in all drug-induced liver injury was $21.0\%-30.0\%$. But criterion for herbal medicine is rather vague and limited objective data hindered objectiveness. Few of single medicinal herbs and combination preparations were associated with hepatotoxic injuries. But because of lack of objectivity, further researches must be conducted to yield more concrete results. Conclusions: yield more concrete results. Incidence figures are largely unknown, and in most cases a causal attribution is not established. The challenge for the future is to systematically research this area, educate all parties involved, and minimize patient risks.

• Journal of Korean Society for Quality Management
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• v.41 no.4
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• pp.623-635
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• 2013

Purpose: The recent major recalls of hazardous products caused consumer product safety acts to be strengthen worldwide. Although the recall system of hazardous products in Korea has been operating based on Framework Act on Product Safety since 2011, the evaluation of product risk has been relied on not the results of objective incident data but the results of illegal product investigations. The purpose of this paper is to propose a product risk assessment model for Korea using injury data. Methods: The authors derived Korea's risk assessment method by analysing the advantages and disadvantages of the most widely used models in advanced countries such as EU's RAPEX RAG and Janpan's R-MAP. In this study, the level of relative frequency and severity of injury are determined based on the objective incident data and the length of hospitalization respectively. In addition, the injury data occurred during 2011 is applied to the proposed risk assessment model for case study. Results: The data analysed in this paper can be classified as high risk, medium risk, low risk, acceptable risk, and safe products through the matrix f rom the combination of the relative frequency and the severity derived. Conclusion: The proposed risk assessment model in this study has advantage obtaining reliable objective results because it uses actual injury data and redeems the drawbacks of the existing models used in advanced countries. Furthermore, because the proposed model shows the high risk products among many, it is expected to be useful especially for customs whose main job is inspecting the imported goods and the government when selecting the target product groups for safety investigation.

• Archives of design research
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• v.15 no.4
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• pp.149-156
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• 2002

The success of a product is only possible on the basis of user preference for products and the user preference for products is greatly influenced by the design. Designers have to understand user preference and convert it into the combination of specified design attribute, and after that they should design products which have the image that they want to get. Then the product will be sure to be a hit. Therefore, on the point of view of design, it is necessary to find oui definitely the consumer preference frame : the relationship among design preference - design images - design attribute. This study will give you guidelines on which designers can select and design some more objective and reliable design factors, finding out the relation of cause and effect by which they can know what kind of product designs their consumers like and how the popular image which that products offer is composed of. Therefore, in this study, after we developed the consumer response framework which is proposed by Bloch(1995) : distinct relationship model among preference - design image adjective - design factors, we analyzed the relationship among preference-design image adjective - design factors through the empirical researches. And then we give the way of design.

• Preventive Nutrition and Food Science
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• v.18 no.2
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• pp.104-110
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• 2013

Presence of Helicobacter pylori is associated with an increased risk of developing upper gastrointestinal tract diseases. Antibiotic therapy and a combination of two or three drugs have been widely used to eradicate H. pylori infections. Due to antibiotic resistant drugs, new drug resources are needed such as plants which contain antibacterial compounds. The aim of this study was to investigate the ability of GutGard$^{TM}$ to inhibit H. pylori growth both in Mongolian gerbils and C57BL/6 mouse models. Male Mongolian gerbils were infected with the bacteria by intragastric inoculation ($2{\times}10^9$ CFU/gerbil) 3 times over 5 days and then orally treated once daily 6 times/week for 8 weeks with 15, 30 and 60 mg/kg GutGard$^{TM}$. After the final administration, biopsy samples of the gastric mucosa were assayed for bacterial identification via urease, catalase and ELISA assays as well as immunohistochemistry (IHC). In the Mongolian gerbil model, IHC and ELISA assays revealed that GutGard$^{TM}$ inhibited H. pylori colonization in gastric mucosa in a dose dependent manner. The anti-H. pylori effects of GutGard$^{TM}$ in H. pylori-infected C57BL/6 mice were also examined. We found that treatment with 25 mg/kg GutGard$^{TM}$ significantly reduced H. pylori colonization in mice gastric mucosa. Our results suggest that GutGard$^{TM}$ may be useful as an agent to prevent H. pylori infection.