• Bulletin of the Korean Chemical Society
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• v.33 no.3
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• pp.1063-1066
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• 2012

• Toxicological Research
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• v.29 no.2
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• pp.107-114
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• 2013

Mass spectrometry (MS) is a very powerful instrument that can be used to analyze a wide range of materials such as proteins, peptides, DNA, drugs, and polymers. The process typically involves either chemical or electron (impact) ionization of the analyte. The resulting charged species or fragment is subsequently identified by the detector. Usually, single mass uses source-induced dissociation (SID), whereas mass/mass uses collision-induced dissociation (CID) to analyze the chemical fragmentations Each technique has its own advantages and disadvantages. While CID is most effective for the analysis of pure substances, multiple-step MS is a powerful technique to get structural data. Analysis of veterinary drugs ampicillin, chloramphenicol, ciprofloxacin, and oxytetracycline serves to highlight the slight differences between SID and CID. For example, minor differences were observed between ciprofloxacin and oxytetracycline via SID or CID. However, distinct fragmentation patterns were observed for ampicllin depending on the analysis method. Both SID and CID showed similar fragmentation spectra but different signal intensities for chloramphenicol. There are several factors that can influence the fragmentation spectra, such as the collision energy, major precursor ion, electrospray mode (positive or negative), and sample homogeneity. Therefore, one must select a fragmentation method on an empirical and case-by-case basis.

• The Bulletin of The Korean Astronomical Society
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• v.44 no.2
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• pp.68.3-68.3
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• 2019

We present the preliminary results on the formation of star clusters by cloud-cloud collision. For this purpose, we perform sub-parsec scale, radiation-hydrodynamic simulations of giant molecular clouds using a sink particle algorithm. The simulations include photo-ionization, direct radiation pressure, and non-thermal radiation pressure from infrared and Lyman alpha photons. We confirm that radiation feedback from massive stars suppresses accretion onto sink particles. We examine the collision-induced star formation and discuss the possibility on the formation of a globular cluster.

• Mass Spectrometry Letters
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• v.2 no.1
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• pp.24-27
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• 2011

Hyperthermal ion/surface collisions of bromotoluene radical cations were studied using perfluorinated (F-SAM) and hydroxyl-terminated (OH-SAM) self-assembled monolayer surfaces in a tandem mass spectrometer with BEEQ geometry. The isomers were differentiated by ion abundance ratios taken from surface-induced dissociation (SID). The dissociation rate followed the order of ortho > meta > para isomers. The peak abundance ratio of m/z 51 to m/z 65 showed the best result to discern the isomers. A dissociation channel leading to tolylium ion was suggested to be responsible for the pronounced isomeric differences. The capability of SID to provide high-energy activation with narrow internal energy distribution may have channeled the reaction into the specific dissociation pathway, also facilitating small differences in reaction rates to be effective in the spectral time window of this experiment. All of the molecular ions experiencing reactive collisions with the F-SAM surface undergo transhalogenation, in which a fluorine atom on the surface replaces the bromine in the incoming ions. This reactive collision was dependent on the laboratory collision energy occurring in ca. 40.75 eV range.

• Journal of the Korean Chemical Society
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• v.17 no.4
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• pp.240-246
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• 1973

An analytic expression for the intensity of collision-induced light scattering obstained by introducing both short-range and long-range effects on the induced anisotropy. By taking argon as a specific example, it is shown that a narrow band at small frequency shifts is caused by long-range effects, while a broad band in the far wing of the spectrum is due to short-range effects. The overall intensity is a synthesis of these two bands and does not follow a simple exponential form. As temperature increases, the intensity at large frequency shifts increases makedly, while at small frequency shifts it changes little.

• Bulletin of the Korean Chemical Society
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• v.34 no.12
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• pp.3641-3648
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• 2013

Energy transfer and bond dissociation of $C-H_{methyl}$ and $C-H_{ring}$ in excited toluene in the collision with $H_2$ and $D_2$ have been studied by use of classical trajectory procedures at 300 K. Energy lost by the vibrationally excited toluene to the ground-state $H_2/D_2$ is not large, but the amount increases with increasing vibrational excitation from 5000 and $40,000cm^{-1}$. The principal energy transfer pathway is vibration to translation (V-T) in both systems. The vibration to vibration (V-V) step is important in toluene + $D_2$, but plays a minor role in toluene + $H_2$. When the incident molecule is also vibrationally excited, toluene loses energy to $D_2$, whereas it gains energy from $H_2$ instead. The overall extent of energy loss is greater in toluene + $D_2$ than that in toluene + $H_2$. The different efficiency of the energy transfer pathways in two collisions is mainly due to the near-resonant condition between $D_2$ and C-H vibrations. Collision-induced dissociation of $C-H_{methyl}$ and $C-H_{ring}$ bonds occurs when highly excited toluene ($55,000-70,400cm^{-1}$) interacts with the ground-state $H_2/D_2$. Dissociation probabilities are low ($10^{-5}{\sim}10^{-2}$) but increase exponentially with rising vibrational excitation. Intramolecular energy flow between the excited C-H bonds occurring on a subpicosecond timescale is responsible for the bond dissociation.

• Structural Engineering and Mechanics
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• v.67 no.1
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• pp.9-20
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• 2018

In this paper, a framework is proposed for dynamic analysis of train-bridge systems with a damaged pier after barge collision. In simulating the barge-pier collision, the concrete pier is considered to be nonlinear-inelastic, and the barge-bow is modeled as elastic-plastic. The changes of dynamic properties and deformation of the damaged pier, and the additional unevenness of the track induced by the change of deck profile, are analyzed. The dynamic analysis model for train-bridge coupling system with a damaged pier is established. Based on the framework, an illustrative case study is carried out with a $5{\times}32m$ simply-supported PC box-girder bridge and the ICE3 high-speed train, to investigate the dynamic response of the bridge with a damaged pier after barge collision and its influence on the running safety of high-speed train. The results show that after collision by the barge, the vibration properties of the pier and the deck profile of bridge are changed, forming an additional unevenness of the track, by which the dynamic responses of the bridge and the car-body accelerations of the train are increased, and the running safety of high-speed train is affected.

• Structural Engineering and Mechanics
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• v.81 no.1
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• pp.69-79
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• 2022

The dynamic responses of a pier-pile-soil system subjected to a barge/flotilla collision are analyzed. A coupled high-speed train and bridge system with a damaged pier after barge/flotilla collision is established by taking the additional unevenness of the track induced by the damaged pier as the self-excitation of the system. The whole process of a CRH2 high-speed train running on the 6×32 m simply-supported PC (prestressed concrete) box-girder bridge with a damaged pier is simulated as a case study. The results show that the lateral displacements and accelerations of the bridge with a damaged pier are much greater than the ones before the collision. The running safety indices of the train increase with the train speed as well as with the number of barges in the flotilla. In flotilla collision, the lateral wheel/rail forces of the train exceed the allowable values at a certain speed, which influences the running safety of the trains.

• Proceedings of the KSR Conference
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• 2011.10a
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• pp.1868-1873
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• 2011

In this paper, a theoretical formulation of a simplified wheel-set model for collision-induced derailments was evaluated by numerical simulations for the wheel-climb derailment and wheel-lift derailment types. The derailment types were classified into the wheel-climb derailment and the wheel-lift derailment according to the friction force direction of the wheel-flange. The wheel-climb derailment type was classified into Climb-up, Climb/Roll-over, and Roll-over-C, and wheel-lift derailment type was classified into Slip-up, Slip/Roll-over and Roll-over-L. To verify the theoretical equations derived for the wheel-climb derailment and the wheel-lift derailment, dynamic simulations using RecurDyn of Functionbay and Ls-Dyna of LSTC were performed and compared for some examples. The derailment predictions of the suggested theoretical formulation were in good agreement with those of the numerical simulations. The direction of the frictional force between the wheel-flange and the rail can be well predicted using the suggested derailment formulation at a initial derailment.

• Mass Spectrometry Letters
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• v.12 no.4
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• pp.179-185
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• 2021

Collision-induced dissociation (CID) combined with electrospray ionization mass spectrometry (ESI-MS) was used to obtain structural information on rat islet amyloid polypeptide (rIAPP) monomers (M) and dimers (D) observed in the multiply charged state in the MS spectrum. MS/MS analysis indicated that the rIAPP monomers adopt distinct structures depending on the molecular ion charge state. Peptide bond dissociation between L₂₇ and P₂₈ was observed in the MS/MS spectra of rIAPP monomers, regardless of the monomer molecular ion charge state. MS/MS analysis of the dimers indicated that D⁵⁺ comprised M²⁺ and M³⁺ subunits, and that the peptide bond dissociation process between the L₂₇ and P₂₈ residues of the monomer subunit was also maintained. The observation of (M+ b₂₇)⁴⁺ and (M+ y₁₀)³⁺ fragment ions were deduced to originate from the two different D⁵⁺ complex geometries, the N-terminal and C-terminal interaction geometries, respectively. The fragmentation pattern of the [M_rIAPP + M_hIAPP]⁵⁺ MS/MS spectrum showed that the interaction occurred between the two N-terminal regions of M_rIAPP and M_hIAPP in the heterogeneous dimer (hetero-dimer) D⁵⁺ structure.