• The Journal of Korean Academic Society of Nursing Education
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• v.18 no.2
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• pp.312-322
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• 2012

Objectives: The purpose of this study was to investigate the factors related to adjustment of college for nursing students and to develop a collective model for successful prediction and concrete paths of the factors. Methods: Data collection was conducted from May 19th 2010 to Jun 4th 2010. Five hundred thirty-one questionnaires were used for data analysis after distributing 560 sheets to senior students in 8 different locations. Data was analyzed with SPSS 18.0 Win program and AMOS 18.0. Results: Mother attachment does not have a direct effect on adjustment to college life but does effect psychological well-being and coping, which indirect adjustment to college life. In addition, the more psychological well-being and coping usage frequency, and the less stress of clinical practice, the higher score of adjustment to college life. According to the results, explanatory power of the model for the college nursing students' adjustment was 62.0%. Conclusions: To improve adjustment to college life, it is recommended to have a direct method of developing psychological well-being and coping improvement program to improve mother attachment. The research is meaningful in a sense that it explains the cause and effect relationship between adjustment to college life and relevant variables to predict comprehensive dimensional explanation of adjustment of college life for nursing students.

• Advances in Traditional Medicine
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• v.10 no.1
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• pp.44-49
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• 2010

An examination of the kinetic properties of UDP-glucose, (1,3)-$\beta$-glucans (callose) synthase, from mung bean seedlings (Sorbus commixta cortex) shows that these enzymes have a complex relationship with UDP-glucose and various effectors. Fluorescence assay showed that deoxynojirimycin increased the inhibitory effect of (1,3)-$\beta$-glucan synthase in a concentration-dependent manner. The inhibitory effect of sakuranetin (34.34%) was higher than that of deoxynojirimycin (80.63%). Disk diffusion method revealed that sakuranetin inhibited the growth of Candida albicans to a 1.5 mm inhibition zone. These results suggest that sakuranetin, isolated from Sorbus commixta cortex extract, can be used as stable antifungal material.

• Journal of Acupuncture Research
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• v.28 no.4
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• pp.143-147
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• 2011

Objectives : The purpose of this study was to examine the effect of needle-embedding therapy against facial wrinkle. Methods : Ten patients with facial wrinkles were treated with needle-embedding therapy. Pictures and satisfaction questionnaire were compared before and after the treatment. And all patients were examined for adverse side effect after needle-embedding therapy. Results : After treatment, facial wrinkles were visibly improved after needle-embedding therapy. There were no adverse side effect except bruise. Conclusions : This study suggests that needle-embedding therapy can improve facial wrinkles.

• JSTS:Journal of Semiconductor Technology and Science
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• v.16 no.5
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• pp.635-640
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• 2016

Tunnel field-effect transistor (TFET) is a promising candidate for the next-generation electron device. However, technical issues remain for their practical application: poor current drivability, shor-tchannel effect and ambipolar behavior. We propose herein a novel recessed-channel TFET (RTFET) with the asymmetric source and drain. The specific design parameters are determined by technology computer-aided design (TCAD) simulation for high on-current and low S. The designed RTFET provides ${\sim}446{\times}$ higher on-current than a conventional planar TFET. And, its average value of the S is 63 mV/dec.

• Journal of Acupuncture Research
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• v.31 no.4
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• pp.163-171
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• 2014

Objectives : The aim of this study was to observe the effect of needle-embedding combined with oriental medical treatment therapy on hemifacial spasm. Methods : 2 patients were treated with needle-embedding therapy with oriental medical treatment. After treatment, we evaluated the effect by Scott's scale. And we checked the satisfaction degree and side effect. Results : After treatment, the grade of spasm classified by Scott's scale was decreased and hemifacial spasm was visibly improved. Conclusions : This study showed that needle-embedding therapy with oriental medical treatment was effective to improve hemifacial spasm.

• Archives of Pharmacal Research
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• v.21 no.1
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• pp.1-5
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• 1998

Rebamipide, 2-(4-chlorobenzoylamino)-3-[2(1H)-quinolinone-4-yl]-propionic acid, a novel antipeptic ulcer agent, has been reported to prevent various acute experimental gastric mucosal lesions and to accelerate the healing of chronic ulcers. Therapeutic effect of rebamipide was investigated with regard to the inhibitory effect on xanthine oxidase activity and type conversion of the enzyme which play a profound role in oxygen radicals generation system. Intraperitoneal administration of rebamipide at 60 mg/kg body weight reduced the xanthine oxidase activity, lipid peroxide content in ammonia induced hemorrhagic lesion. These results suggest that the therapeutic effect of rebamipide on gastric mucosal lesion may be in part due to the inhibitory activity of xanthine oxidase and type conversion rate of the enzyme.

• Macromolecular Research
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• v.12 no.5
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• pp.484-489
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• 2004

We have prepared a phenothiazine-based nonlinear optical (NLO) chromophore that displays a fairly high microscopic nonlinearity through intramolecular charge transfer. The phenothiazine unit plays important roles of contributing its high electron donating ability and connecting the resonance pathway through a conjugative effect in the cyclized ring adjacent to the aromatic ring. Theoretical calculations and an absorption spectroscopic study provided useful information concerning the microscopic nonlinearity of the chromophores. We investigated the electro-optic (EO) properties of the guest-host systems in amorphous polycarbonate containing the synthesized chromophores at different concentrations under different poling temperatures. A real-time pole and probe method provided a much greater amount of information regarding how the EO properties can arise and how they can be optimized.

• Biomedical Science Letters
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• v.28 no.4
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• pp.307-311
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• 2022

The extract of EA lacks studies showing its efficacy other than that it contains caffeic acid, an active compound that has antioxidant and neuroprotective effects on nerve cells. Therefore, in this study, we attempted to determine the effectiveness of EA extraction. In this study, we performed a DPPH assay to determine the antioxidant potential of EA. And then, the cytotoxic concentration of EA in HaCaT keratinocytes was determined, and the antioxidant effect was determined by measuring the malondialdehyde (MDA). The results of DPPH, a chemical antioxidant assay, clearly demonstrated the antioxidant capacity of EA extracted with distilled water. In addition, cell-based assays provide useful information on the protective effect of EA on oxidative stress-induced apoptosis.

• The Journal of Korean Obstetrics and Gynecology
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• v.21 no.1
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• pp.55-82
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• 2008

Purpose: In this study, we evaluated anti-inflammatory activity and anti-thrombosis effect of Manbunbang(MBB) prescribed to chronic PID patients. Methods: We studied inhibitory effect of platelet aggregation, suppression effect of GPIIb/IIIa activity and inhibitory effect of $TXB_2$ and $PGE_2$ biosynthesis which were caused by ADP, epinephrine, collagen and arachidonic acid in vitro. And suppression of pulmonary embolism, changes of related factors in dextran coagulation condition model and anti-oxidative effect of oxidative damage were studied in vivo. Results: MBB extract showed LD50 of $200\;{\mu}g/ml$ or higher in mouse lung fibroblast cells, and significantly decreased the GPT and GPT level in dextran coagulation condition model compared to the control. MBB extract showed dose-dependent inhibition effect on platelet coagulation induced by ADP, epinephrine, collagen, arachidonic acid. MBB extract showed dose-dependent inhibition effect on GPIIb/IIIa activities compared to the control. MBB extract significantly suppressed TXB2 and PGE2 biosynthesis compared to the control. MBB extract suppressed pulmonary embolism triggered by collagen and epinephrine by 37.5% compared to the control. MBB extract significantly suppressed the decrease of speed of bloodstream caused by blood coagulation in dextran coagulation condition model compared to the control. Concluson : The results strongly suggest the anti-inflammatory activity of Manbunbang through anti-thrombus. Various applications using Manbunbang on inflammatory diseases are anticipated. Anti-oxidative efficacy comparison data between the Manbunbang prescription and the drug compositions may be used as important clinical information, and further investigation of anti-oxidative activities of Chrysanthemum indicum and Rhemaniae Radix should be followed.

• The Journal of Internal Korean Medicine
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• v.24 no.2
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• pp.315-328
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• 2003

This study was performed to investigate the effect of Bunsimgieum on antitumor effect after sarcoma-180 cells transplantation into peritoneal cavity or left groin and immune responses on the depressed immunity induced by methotrexate in mice. The Bunsimgieum extract of 10mg/kg was orally administered 14 days for antitumor effects and 21 days for immune responses. 50% inhibitory concentration($IC_{50}$) of SUN-1, SUN-C4, and SUN-396 cancer cell, mean sunvival days and body weight of tumor bearing mice, and growth of tumor mass for antitumor effect; delayed type hypersentivity, hemagglutinin titer, hemolysis titer, rosette forming cells, natured killer cell activity, lymphocyte transformation, productivity of interleukin-2, and phagocytic activity for their immune responses were measured in ICR mice. Significance in antitumor effect is noted in the enlongation of mean life days and inhibition of tumor growth(p<0.01, respectively). Significance of immune responses is also noted in hemolysis titer, lymphocyte transfumotion, IL-2 productivity, phagocytic activity, and natural killer cell activity at E/T ratio 100:1(p<0.01, respectively). Significant in rosette cell formation was seen at dosage of 20mg/kg(p<0.01). However, Difference of body weight as antitumor effect, delayed type hypersensitivity, and hemagglutinin titer were not shown significantly. According to the above results, it could be suggested that Bunsimgieum has prominent antitumor and immunity enhancing effect.