• Korean Journal of Clinical Pharmacy
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• v.20 no.2
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• pp.128-137
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• 2010

This review summarizes gender differences in pharmacokinetics, pharmacodynamics, and adverse drug reactions. Gender differences in pharmacokinetics are categorized by four major factors: absorption/bioavailability, distribution, metabolism, and elimination. There are sex-based differences in gastric emptying time, gastric alcohol dehydrogenase activity, apparent volume of distribution, ${\alpha}1$-acid glycoprotein level, phase I (CYP) and phase II metabolizing enzymes, glomerular filtration rate, and drug transporters. This review also reports gender differences in pharmacokinetics and pharmacodynamics of cardiovascular agents, central nervous system acting agents and antiviral agents. In addition, it has been reported that females experience more adverse reactions such as coughing, tachycardia, nausea, vomiting, rash, hypersensitivity, hepatotoxicity, and metabolic disorder after taking cardiovascular, central nervous system acting and antiviral agents. Therefore, in order to provide optimal drug dosage regimens both in male and female, gender differences in pharmacokinetics, pharmacodynamics, and adverse drug reactions must be considered.

• Journal of Korean Academic Society of Home Health Care Nursing
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• v.19 no.2
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• pp.162-172
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• 2012

Purpose: The purpose of this study is to explore the subjective experiences of relapse and treatment among the alcoholics. Methods: Phenomenological methodology was used for the study. Participants were seven people with inpatient alcoholics at the alcohol treatment center at K hospital in K province. Data were collected via in-depth interviews from March to September, 2012 and analyzed using Colazzi's framework. Results: Six themes and seventeen meanings were formulated for the relapse and treatment experiences of participants with alcoholism. Six themes were 'Lack of true insight', 'Lack of strength to live a life', 'Unable to overcome an urge to drink', 'Being drawn away from others', 'Falling into the powerlessness and despair', and 'Being foothold of self-growth'. Conclusion: The results from this study revealed the relapse experiences among alcoholic patients. Therefore, the findings can provide the framework and direction for developing the relapse prevention program for alcoholic patients. In addition, practitioners in the treatment center or hospital need to consider their relapse and treatment experience.

• Asian Oncology Nursing
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• v.12 no.3
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• pp.237-245
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• 2012

Purpose: The purpose of this study was to identify attributes of the concept of cancer survivorship. Methods: Walker & Avant's concept analysis framework (2005) was used to review the medical & nursing text books, medical and nursing research articles related to cancer survivorship and published from 1985 to 2011. Results: There were nine aspects of the concept of cancer survivorship: A process, liminality, uncertainty, life-changing experience, complexity, unique experience, duality of positive and negative aspects, partnership, and need for support. Antecedents of cancer survivorship were cancer diagnosis and perception as a cancer survivor. Empirical referents of cancer survivorship were survival rate, quality of life, adaptation to the survivorship experience, and health-related hardiness, social support, spirituality, and health behavior. The consequences of cancer survivorship were effects on the physical, psychosocial, spiritual and socio-economic well-being of the patients. Conclusion: This concept analysis of cancer survivorship is expected to contribute to promotion of survivorship care in the clinical field by removing conceptual ambiguity and confirming the true meaning of survivorship care.

• Korean Journal of Human Ecology
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• v.17 no.5
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• pp.807-819
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• 2008

The purpose of this study was to find out the factors which were related to the delinquent behaviors among 2nd years high school in Geoje, Korea. The subjects were 618 high school students. Data were collected by self-reported questionnaires from March to April, 2007. Data were analyzed by SPSS WIN 12.0 program with mean, standard deviation, t-test, ANOVA, Kruskal-Wallis test, Scheffe's test, Pearson's correlation, and stepwise multiple regression. Students' delinquent behaviors differed by experience of smoking, experience of drinking, harmony of family, mother's education, father's smoking mother's smoking, academical class, satisfaction of school-life, friends who smoked, drank alcohol, did drugs, and punished friends. Students' stress and depression had positive correlation with their delinquent behaviors. The result of stepwise multiple regression showed that punished friends, experience of smoking, depression, father's smoking satisfaction of school-life were significant related factors to delinquent behaviors among high school students. It is necessary for home, school, and community to cooperate with each other in preventing high school students from delinquent behaviors.

• Journal of The Korean Society of Integrative Medicine
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• v.8 no.4
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• pp.253-263
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• 2020

Purpose : The purpose of this study was conducted to compare the fear of falling, self-efficacy and fall prevention behavior according to the fall experience of the elderly. Methods : The subjects of this study were 162 elderly in B metropolitan city. The data collection period was from September 10th to November 30th of 2018. The collected data was processed using SPSS 21.0 and was analyzed using descriptive statistics, t-test, ANOVA, Scheffe's test. Results : The mean scores for fear of falling according to the fall experience and no fall experience of the elderly were 2.28±0.63 and 1.84±0.64 respectively and the results showed that fear of falling (t=4.26, p<.001) and self-efficacy of falling (t=3.88, p<.001) were significantly different between the two groups, but the mean scores for fall prevention behavior according to the fall experience and no fall experience of the elderly were 1.63±0.20 and 1.67±0.17 respectively and there was no significantly different in fall prevention behavior (t=-1.16, p=.25). Fear of falling according to the fall experience was significantly different by age (F=3.25, p<.05) and physical activity related to daily life (F=13.22, p<.001). Self-efficacy according to the fall experience was significantly different by age (F=3.03, p<.05), income per month (F=3.74, p<.05) and physical activity related to daily life (F=11.99, p<.001). But fall prevention behavior was no significantly different of general characteristics. Fear of falling according to the no fall experience was significantly different by age (F=3.37, p<.05), marriage status (F=3.37, p<.05), education level (F=5.15, p<.01), income per month (F=3.58, p<.05) and physical activity related to daily life (F=15.71, p<.001). Self-efficacy according to the no fall experience was significantly different by sex (t=2.32, p<.05), age (F=5.20, p<.01), marriage status (F=5.04, p<.01), education level (F=6.55, p<.001), income per month (F=5.99, p<.001) and physical activity related to daily life (F=18.86, p<.001). Fall prevention behavior was significantly different by marriage status (F=3.51, p<.05). Conclusion : The results of this study suggest the following : it is necessary to develop a program that can lower the fear of falling in the elderly and to increase the self-efficacy of falling, and to develop an education program that can improve the elderly's practice of fall prevention behavior regardless of the fall experience and to verify its effectiveness.

• The Journal of Korean Society for School & Community Health Education
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• v.13 no.2
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• pp.59-76
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• 2012

Objectives: This study Development of a healthy college life, and effective for smoking cessation programs for education is to utilize as a basis for. Methods: The study employs frequency analysis, cross-analysis and correlation analysis through SPSS Win 17.0 on 296 (84.6% of total participants) from the entire participants of 350. The significance test is delivered with ${\chi}^2$-test. Results: 1) The participants consist of 47.7% (147) males and 52.3% (161) females. 78.2% (241) has experience of smoking cessation program at high school. 61.7% (190) has parents who are smoking. 40.9% (126) answers that they are currently smoking while 59.1% (182) answers that they are not. 2) When asked about their perception on quitting smoking, 81.2% (250) says that non-smokers are distressed by others' smoking. 74.0% (228) has unpleasant experience with cigarette smoke. 3) The analysis of the relation between smoking cessation program at high school and smoking shows that 63.8% of the ones who have experience of the program are non-smokers while 68.7% of those with no experience of the program are smokers. 4) Among those who have tried to quit smoking, 73.9% have experience of smoking cessation program at high school. 31.8% of these participants also reveal their interest in the cessation program. 5) In the analysis of the correlation between smoking habits, the experience of smoking cessation program at high school is closely related to non-smoking while current smoking habit is highly related to the strong interest in participation of cessation program. Also, the more interest they have in participating, the stronger needs they feel for smoking prevention program at college. Conclusion: Therefore, the last phase of education-related courses at the University of educated and credits granted through open non-smoking pledge, non-smoking club, non-smoking camps, training programs, such as smoking in non-smoking education and programs for students interested in openness and participation must be done will.

• Journal of East-West Nursing Research
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• v.22 no.2
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• pp.87-95
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• 2016

Purpose: The purposes of this study were to develop a community-based Mind Subtraction meditation program for cancer survivors and examine the effectiveness of the developed program on quality of life, life satisfaction, and expectancy of satisfactory life in cancer survivors. Methods: This study used a one group, pretest-posttest design. A 5-week community-based meditation program for cancer survivors was offered twice a week with each session up to 2 hours. 10 cancer survivors who had completed cancer treatments participated in this study. Data were collected using self-reported questionnaires and personal journals about the meditation experience from September 10 to December 11, 2015 at a health center branch in Seoul, South Korea. Results: There were statistically significant differences in physical domain of quality of life (QOL) expectancy of satisfactory life. Conclusion: This study shows that the community-based Mind Subtraction meditation program for cancer survivors can be considered as an effective nursing intervention to improve quality of life and expectancy of satisfactory life among cancer survivors in a community setting.

• Journal of Korean Academy of Nursing
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• v.29 no.5
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• pp.1021-1029
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• 1999

Koreans rarely complain of depression or other psychological problems because mental illness is viewed as a stigmatizing and threatening experience. This study examined the relationships among stressful life events, close relationships, self-esteem. and depression in 400 college women aged 18 to 30 years. Depression was positively related to stressful life events (r＝.21, p＝＜.01). Depression and stressful life events were negatively associated with self-esteem (r＝-.67; r＝-.11, p＜.01; p＜.05 respectively). Close relationships with women and men friends were each negatively associated with depression (r＝-.24; r＝-.16, p＜.01; p＜.05). Close relationships with women and men friends were positively associated with self-esteem (r＝.23; r＝.20, p＜.01). Forty nine percent of variance in depression rates in this sample was explained. After adjustment for degrees of freedom, a total of 49% of the variance in depression was explained by self-esteem and stressful life events. This investigation into the relationships among the variables influencing depression for college women is a critical issue as health professionals need to be aware that college women are at considerable risk for depression. Effective psychosocial interventions are those designed for specific populations to meet unique care needs and since young Korean women may be at considerable risk for depression.

• Journal of Korean Academy of Nursing
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• v.24 no.3
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• pp.499-510
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• 1994

The purpose of this study was to Identify the self-actualization level of Junior College Nursing Students and to analyze the variables that may be related to self-actualization. A convenient sample of 346 students were selected from three colleges located in Seoul and Kyungki-Province. The data were collected using a direct survey method from September17to October 2, 1992. The instrument used for this study was the self-actualization test modified by Kim & Lee(1983). The collected data were analyzed using percentages, means, 1-test, X$^2$-test, ANOVA and Pearson’s correlation coefficient, with the SPSSPC$^{+}$ Package. The results of this study are as follows : 1) The self-actualization level of subjects was moderate. The subjects showed higher scores in the areas of Self actualizing Values and Nature of Man than the standardized normal groups. The subjects showed lower scores in the areas of Inner Directed Existentiality, Self acceptance and Capacity for Intimate Contact. 2) The subjects attending day junior colleges showed higher scores in the areas of Time competent, Existentiality and Self Acceptance than those attending college in the evening. The subjects attending evening junior colleges showed higher scores in the areas of Spontaneity than those attending college by day. 3) The junior students showed higher scores in the areas of Feel-ing Reactivity than freshman. The students with no religion showed higher scores in the areas of existentiality than those who had a religion. The group who had the experience of failure on the college entrance examination showed lower scores in the areas of Nature of Man than those without this experience. Those who chose their major voluntary showed scores higher in the areas of I nor Directed, Self Actualizing Values, Spontaneity and Self regard than the unsatisfied group. The group satisfied with college life showed higher scores in the areas of Time Competent, Inner Directed, Self Actualizing Values and Self Regard than the unsatisfied group. In conclusion self actualization level depends on motivation of choice, satisfaction with nursing as a major and satisfaction with college life. Therefore, and effective guidance program is required to improve motivation and satisfaction with nursing as a major and with college life.

• The Journal of Korean Obstetrics and Gynecology
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• v.26 no.1
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• pp.69-81
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• 2013

Purpose: The aim of this study is to determine associated factors affecting the utilization of Medical Care for an overactive bladder. Methods: Total 114 women with overactive bladder participated in this study. Patients were categorized in two groups, the patients with treatment experiences for an overactive bladder(n=40) and without treatment experiences for an overactive bladder(n=74). Patients completed Overactive Bladder Severity Score, Beck Depression Inventory, King's Health Questionnaire, and questionnaires on treatment experience. The results were analysed using SPSS for Windows 12.0k. All statistical tests were two-sided with a p-value < 0.05 being significant. Results: Patients with treatment experience had a greater score on KHQ, OABSS, BDI and had longer symptom duration period than those without treatment experience. And only Impact of Life(P=0.004), Role Limitation(P=0.004), Social Limitation(P=0.007), Emotion(P=0.035), Sleep/Energy(P=0.001), Incontinence Severity Measures(P=0.012) among KHQ domains were statistically significant difference between two groups. Conclusions: The most influencing factor associated with utilization of Medical Service in overactive bladder is the impact of the patient's quality of life.