• Molecules and Cells
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• v.39 no.6
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• pp.468-476
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• 2016

PLZF-expressing invariant natural killer T cells and CD4 T cells are unique subsets of innate T cells. Both are selected via thymocyte-thymocyte interaction, and they contribute to the generation of activated/memory-like CD4 and CD8 T cells in the thymus via the production of IL-4. Here, we investigated whether $PLZF^+$ innate T cells also affect the development and function of $Foxp3^+$ regulatory CD4 T cells. Flow cytometry analysis of the thymus and spleen from both CIITA transgenic C57BL/6 and wild-type BALB/c mice, which have abundant $PLZF^+$ CD4 T cells and invariant natural killer T cells, respectively, revealed that $Foxp3^+$ T cells in these mice exhibited a $CD103^+$ activated/memorylike phenotype. The frequency of $CD103^+$ regulatory T cells was considerably decreased in $PLZF^+$ cell-deficient $CIITA^{Tg}Plzf^{lu/lu}$ and $BALB/c.CD1d^{-/-}$ mice as well as in an IL-4-deficient background, such as in $CIITA^{Tg}IL-4^{-/-}$ and $BALB/c.IL-4^{-/-}$ mice, indicating that the acquisition of an activated/ memory-like phenotype was dependent on $PLZF^+$ innate T cells and IL-4. Using fetal thymic organ culture, we further demonstrated that IL-4 in concert with TGF-${\beta}$ enhanced the acquisition of the activated/memory-like phenotype of regulatory T cells. In functional aspects, the activated/ memory-like phenotype of Treg cells was directly related to their suppressive function; regulatory T cells of $CIITA^{Tg}PIV^{-/-}$ mice more efficiently suppressed ovalbumin-induced allergic airway inflammation compared with their counterparts from wild-type mice. All of these findings suggest that $PLZF^+$ innate T cells also augmented the generation of activated/memory-like regulation via IL-4 production.

• Korean Journal of Psychosomatic Medicine
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• v.25 no.2
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• pp.120-128
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• 2017

Objectives : Although antipsychotics are commonly used to control symptoms of delirium, there is a lack of research on the prescription pattern and its clinical effects. The purpose of this study was to investigate the effect of antipsychotics prescription pattern on clinical course of delirious patients consulted to psychiatry. Methods : During the period from July 2016 to February 2017, 212 patients who were referred for delirium were reviewed for their medical records. The duration of delirium was monitored using CAM-ICU, and duration of admission, mortality, and delirium at discharge were reviewed. Clinical course was compared among three groups according to the antipsychotic drug administration pattern: Continuous use group, optimal use group and PRN use group. Results : The pattern of taking antipsychotic medication longer than duration of delirium did not associated with better clinical course compared with the pattern of adapting to the period of delirium and rather increased the risk of taking antipsychotic medication at discharge. When used for a shorter period than the delirium period, it was associated with poor clinical course. Conclusions : The results of this study suggest that a strategy to administer antipsychotics for a minimum period, according to periods of delirium, is appropriate. Also, efforts are needed to minimize the use of antipsychotic drugs after recovery from delirium.

• Korean Security Journal
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• no.31
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• pp.47-71
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• 2012

This study is to analyse the effect on self-effectiveness of a course decision of duty stress in the college students related to guard major study. For this, the college students related to guard major study in Gwang-ju and Jeonnam region were selected as a universe at April 2011. And a sampling was practiced as a random sample. A question investigation was used in a entry method of self-estimation. Furthermore a total of 171 person(85.5%) was used as final analysis data. The collected data were employed in a statistics program of SPSS for win version 17.0. And used in a way of Pearson's interrelation analysis and Multiple Regression Analysis. The conclusion was as follows. Firstly, family surroundings stress and studies stress of duty stress affected beneficially statistically a goal selection of self-effectiveness of course decision. Family surroundings influenced upon it positively. And studies effected on it negatively. Secondly, all factors of duty stress didn't affect beneficially statistically the work information of self-effectiveness of course decision. Thirdly, school surroundings stress of duty stress influenced upon positively statistically the problem solution of self-effectiveness of course decision. Fourthly, personality stress and duty anxiety stress affected beneficially statistically the future plan of self-effectiveness of course decision. Personality influenced upon it negatively and duty anxiety affected it positively.

• Journal of Hospice and Palliative Care
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• v.22 no.4
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• pp.166-173
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• 2019

Purpose: High-quality hospice and palliative medicine curricula are necessary in Korean medical schools. This study evaluated changes in students' knowledge and attitudes toward both hospice and palliative care following the completion of a course on these topics, as well as the course's overall role in the basic medical education curriculum. Methods: Questionnaires measuring knowledge and attitudes were collected before and after the course from 76 fourth-year medical students, who had received instructions integrating both hospice and palliative care in 2016. Results: The questionnaire item "Select the correct answer on the use of opioid pain control in hospice and palliative care" changed the most in terms of number of correct answers pre- and post-course (3.50 and 5.32, respectively; P<0.001). Pre- and post-course, the numbers of students who answered "Strongly Agree" and "Agree" to questions concerning their attitudes toward hospice and palliative care ("I know the purposes and roles of hospice and palliative care") were 17 (22.4%) and 65 (85.6%), respectively (P≤0.001). Affirmative responses also increased for "As a pre-physician, I know when to describe and advise hospice and palliative care to patients", from 22 (28.9%) to 65 (85.6%; P≤0.001). Conclusion: This study showed that comprehensive hospice education in the form of an integrated educational course might promote changes in medical students' knowledge and attitudes toward hospice and palliative medicine.

• Journal of Korean Academy of Fundamentals of Nursing
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• v.7 no.1
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• pp.97-108
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• 2000

The purpose of this study was to assess the present status of the course content of Fundamental Nursing in accordance with the study objectives which were developed for the National Qualifying Examination by the first Faculty-Workshop in January, 1999 and the study objectives as related to other Nursing courses. The study sample included all schools of nursing and the members of the faculty for Fundamental Nursing of seventy schools(66.7%), out of the target population of 105, responded to a questionnaire which was developed by the research team. The collected data were analyzed by frequencies, percentages, means, and standard deviation using the SAS(Statistical Analysis System). The results are as follows : 1) According to this survey the course content of Fundamental Nursing as described in the study objectives for the National Examination, 223(86.77%) study objectives were included in the course of Fundamental Nursing by more than 70% of the schools of nursing, But twenty-three of the study objectives are not included by $30{\sim}50%$ of the schools of nursing. They consider this content to be taught in other courses. The study objectives, which less than 50% of the schools reported as being included in their course in Fundamental Nursing were, all study objectives for 'nursing assessment(communication)', 'nursing assessment (physical examination)', 'record and report', 'sex', and 'use of computer program for nursing diagnosis' and 'use of computerized nursing planning program' 2) Items that were not included in the study objectives for Fundamental Nursing but were included in course content for over 50% of the schools included, 'health of individual, family, community', 'change of nursing practice'. 'professionality of nursing' and all of the study objectives belonging to 'loss and grief' and 'nursing during all stages of surgical operations'. We hope that these results will be helpful in modifying the study objectives for the National Examination as developed by the first Faculty-Workshop and recommend the need for continuous survey research to produce content that is in accordance with study objectives and a National Examination that reflects the content of Fundamental Nursing.

• Women's Health Nursing
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• v.9 no.1
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• pp.5-17
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• 2003

Purpose : The purpose of this study was 1) to classify university student's attitudes toward sex, 2) to confirm the effects of sexuality course on sex-role stereotypes and sexual attitude in university student s. Method : The subjects in this study were 212 K university students in Kangwon Province between 3/7/2001 $\sim$ 6/13/2001. The instruments used for this study were the general characteristics, sexual attitude and sex-role stereotypes. The data was analyzed by frequency, percentage, mean, standard deviation, paired t-test, ANOVA, Pearson correlation coefficients, Factor analysis and Cronbach's $\alpha$ using the SPSS program. Result : 1. University students' attitude toward sex are divided into three types. Type I are called open mined : 16, 33, 28, 10, 18, 2, 30, 25, 26, 27, 22, 19, 29, 21, 9, 5 items. Type II are supporters of virginal purity : 8, 6, 31, 17, 14, 33 items. Type III express love through sexual intercourse : 20, 24, 7, 3, 15, 32 items. 2. There was a significant difference in the appearance and occupational characteristics of sex-role stereotypes before and after the sexuality course (t=2.562, p<.05). 3. In Type III, there was a significant difference in sexual attitude before and after the sexuality course (t=3.576, p<.0001). 4. The data showed the relationships between type III of sexual attitude and sex-role stereotypes (r=-.3 15, p<.0001). 5. Sex-role stereotypes according to the demographic characteristics before sexuality course were significantly different by age, gender, experience of military service, experience of sex edu cat ion an d experience of sexual intercourse. Sex-role stereotypes according to the demographic characteristics after sexuality course were significantly different by gender and experience of sexual intercourse. 6. Sexual attitude according to the demographic characteristics before sexuality course were significantly different by maj or (type I), age, grade, experience of military service and experience of sexual intercourse (type II), age, grade, gender, experience of military service, experience of sex education and experience of sexual intercourse. Sexual attitude according to the demographic characteristics after sexuality course were significantly different by religion and major(type I), age and grade(type II), age, grade, gender, religion and experience of sexual intercourse. Conclusion : This study showed that a sexuality course was effect ive in changing the sex-role stereotypes and sexual attitude of university students.

• English Language & Literature Teaching
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• v.17 no.3
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• pp.57-71
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• 2011

The purpose of this study is to investigate the possibility of the use of reading aloud as a way of teaching English reading in a formal college-level English reading classroom. The study tried to examine the effects of reading aloud on the development of English reading ability in terms of comprehension and speed and the students' perceptions of the use of reading aloud in an English reading classroom. The participants of the study were 36 third year students at a college. The results of the cloze test and reading speed test showed that reading aloud had a positive effect on the improvement of English reading ability. The students received higher scores in the cloze test after the course and read a text faster than before the course. The analysis of the course evaluation questionnaire indicated that the students in the study showed positive attitudes toward the use of reading aloud in an English reading classroom. Most of the students reported that reading aloud was an effective way of improving their English reading comprehension and speed. However, the students were not fully satisfied with the reading materials used in the study. The results of the present study indicated that reading aloud may be incorporated into a formal English reading classroom effectively.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.17 no.1
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• pp.57-60
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• 2014

Acute acalculous cholecystitis (AAC) is an inflammation of the gallbladder in the absence of demonstrated stones. AAC is frequently associated with severe systemic inflammation. However, the exact etiology and pathogenesis of AAC still remain unclear. Acute infection with Epstein Barr virus (EBV) in childhood is usually aymptomatic, whereas it often presents as typical infectious mononucleosis symptoms such as fever, cervical lymphadenopathy, and hepatosplenomegaly. AAC may occur during the course of acute EBV infection, which is rarely encountered in the pediatric population. AAC complicating the course of a primary EBV infection is usually associated with a favorable outcome. Most of the patients recover without any surgical treatment. Therefore, the detection of EBV in AAC would be important for prediction of better prognosis. We describe the case of a 10-year-old child who presented with AAC during the course of primary EBV infection, the first in Korea, and review the relevant literature.

• Journal of Integrative Natural Science
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• v.12 no.2
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• pp.58-68
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• 2019

Critical thinking is essential to implementing the nursing process requiring timely decision making. The study examined the effects of a critical thinking course for nurses in the RN-BSN program. The study used a pre- and post-test design with a control group. The experimental group was a convenience sample of 24 working nurses attending a health college. The control group was 24 fellow nurses. The nursing process-based critical thinking course was provided to the experimental group two and half hours a week for 8 weeks. Teaching methods included lectures followed by a summary and quiz, brainstorming and action learning, and lecturer feedback. A pamphlet about views of professional occupation was provided to the control group. The data were collected using self-report questionnaires and analyzed to examine differences in the test scores before and after the intervention. The scores of critical thinking disposition, problem-solving process, and clinical competence increased significantly in the experimental group but did not in the control group. The difference between the two groups was also statistically significant in critical thinking disposition, problem-solving process, and clinical competence. It is necessary that a robust educational program or training to enhance critical thinking ability of nurses are provided in clinical settings and that nurses keep going on thinking critically in their practice.

• Journal of Engineering Education Research
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• v.25 no.5
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• pp.94-103
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• 2022

In this study, we examined the cases of online video classes conducted under the COVID-19 situation for 46 first-year students majoring in electrical engineering at a 3-year college in Gyeongnam. The research was carried out according to the course development process so that classes could be conducted efficiently, focusing on electromagnetism(1) course in the second semester of the first year. The online class consisted of uploading PPT recorded videos and lecture materials to the LMS and giving assignments. The contents of the study were in the scope of examining learners' perceptions through online learning contents, assignment submission, mutual feedback between instructors and learners, university-level lecture evaluation, and free opinions on online video-based electromagnetism(1) classes. As a result of the study, it was confirmed that online lecture review and problem-solving are particularly important for understanding lecture materials, and also given the nature of engineering subjects that require plenty of mathematical expressions, the detailed and immediate feedback provided by instructor enhances learners' class satisfaction and understanding. Based on these, the direction of online classes to be developed after the COVID-19 pandemic and teaching and learning methods suitable for the characteristics of subjects were discussed.