• 한국임상약학회지
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• 제21권2호
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• pp.170-181
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• 2011

Purpose: There is considerable variability in rates of hospitalization for patients with community-acquired pneumonia (CAP) in part because of physicians' uncertainty in assessing the severity of illness at presentation. The purpose of the study was to examine the current treatment patterns and factors influencing the Pneumonia Severity Index (PSI) and clinical outcomes in the patient with CAP. Method: The retrospective data collection of the patients with CAP was conducted and the data were reviewed. The collected data included demographic, clinical, laboratory and microbiological medical information. All patients were stratified into three risk groups according to PSI: low risk (PSI score I-II), moderate risk (III) and high risk (IV-V) groups. The examined treatment patterns were the appropriateness of admissions, category of antibiotics used. The prognostic factors associated with PSI and clinical outcomes were examined. Results: One hundred and six patients' medical data were reviewed. The overall appropriateness of admissions was low presenting many of patients were admitted or intensely treated in the hospital despite of lower risk of prognosis and treated with intravenous antibiotics instead of oral fluoroquinolones. Primary pneumonia pathogens were Klebsiella pneumoniae (27%) and Streptococcus pneumoniae (21.6%). Mean LOS was 8.5 days and was significantly longer (10.0days) (p<0.001) in high risk group. The patients with age >65 (p<0.001), diabetes mellitus (p<0.001), mental alteration (p<0.001), and/or $PaO_2$ <60 mmHg (p<0.001) had a tendency to have higher PSI. The prognostic factors associated with longer LOS were age >65 years (p=0.008), mental status alteration (p<0.001), dyspnea (p=0.002) and PSI score (p=0.001). The prognostic factors associated with mortality were congestive heart failure (p=0.038), systolic blood pressure <90 mmHg (p=0.002) and arterial pH <7.35 (p=0.013). Conclusion: Most of patients were found to over-utilize medical service according to appropriateness of admissions. The elderly, mentally altered patients with low $PaO_2$ had higher PSI score with increased risk of LOS. The mortality could be increased in the patient with disease state of congestive heart failure, high blood pressure, and/or acidosis.

• Annals of Clinical Neurophysiology
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• 제13권2호
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• pp.71-79
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• 2011

Geographical differences in the incidence of amyotrophic lateral sclerosis (ALS) have been reported, and there are still many unresolved problems. The incidence as well as epidemiologic data of ALS is not known in Korea. Web-based multicenter registry of ALS, the Korean ALS registry, was established at January, 2011. The aim of "the Korean ALS registry" is the following: (1) to establish a database for the prospective collection of epidemiological information; (2) to assess the incidence and prevalence; (3) to find the temporal and geographic trends in the disease; (4) to define the full clinical spectrum of the disease; (5) to develop treatment guideline based on the database.

• 대한임상검사과학회지
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• 제38권3호
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• pp.147-151
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• 2006

Although various automated CBC analyzers with different WBC analytical principles were consequently introduced to clinical laboratory, the specific information concerning the suitability or unsuitability of aging samples is scarce. For this reason, we studied the effect of storage duration and temperature on CBC parameter in SE-9000 (SYSMEX Medical Electronics Co., Ltd., Kobe, Japan), automated CBC analyzer. We tested 32 K3-EDTA specimens with SE-9000 during 72 hours. Specimens were kept at room temperature (RT) and refrigerated and were analyzed at 0 hr, 4 hr, 8 hr, 24 hr, 48 hr and 72 hr after the collection of the specimens. The percentage changes from initial value for each parameters were calculated. Among the CBC parameters, hemoglobin, red blood cell count, mean corpuscular hemoglobin and platelets were stable for the study period at both temperatures. The mean corpuscular volume (MCV), hematocrit (Hct) and red cell distribution (RDW) increased and the mean corpuscular hemoglobin concentration (MCHC) decreased over time at room temperature. These parameters were stable when refrigerated. The leukocyte count was stable during 72hr at RT and when refrigerated. At room temperature, the relative percentages of neutrophils tend to increase, whereas those of lymphocyte and monocytes tend to decrease after 48 hours. When refrigerated, those of neutrophils and monocytes tend to increase, whereas those of lymphocytes tend to decreased over time. CBC parameters of refrigerated specimen were reliable for 72 hr for the exception of differential count from 24 hr but many CBC parameters, such as MCV, Hct, MCHC, RDW and differential count of leukocyte of blood stored at room temperature for 24 hr were unreliable.

• 인터넷정보학회논문지
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• 제22권1호
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• pp.89-98
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• 2021

지역사회획득폐렴은 만성폐쇄성페질환 환자 사망의 중요 원인 질환이며 폐렴구균은 폐렴의 중요 원인균이다. 폐렴구균에 의한 폐렴을 예방하는 대표적인 방법으로는 폐렴구균백신과 독감백신의 접종을 들 수 있다. 국내 주요 7개 대학병원에서는 전향적, 다기관, 코호트 연구를 통하여 폐렴으로 입원한 만성폐쇄성폐질환 환자를 대상으로 폐렴구균예방접종과 독감예방접종여부에 따라 폐렴의 중증도에 차이가 있는지에 대해 연구하였다. 본 연구의 목적은 다기관 연구자들이 만성폐쇄성폐질환 환자의 데이터를 효과적으로 수집하고 관리하도록 도움을 주는 온라인 등록 시스템을 구축하는 것이다. 본 연구에서는 기존의 오프라인 임상 연구의 단점을 보완하기 위해 정확한 데이터의 입력과 편리한 데이터 완성, 그리고 실시간 데이터 관리 등의 세 가지 기본 전략을 제시하였다. 개발된 온라인 등록 시스템은 다기관 임상 연구에 활용되어 그 성능을 평가받았다.

• 대한한방소아과학회지
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• 제38권1호
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• pp.10-22
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• 2024

Objectives This bibliometric analysis aimed to determine the status of pediatric acupuncture research. Methods Relevant bibliographic information up to January 9, 2024, was collected through searches in the Web of Science Core Collection. Bibliographic information was preprocessed for data analysis and analyzed using VOSviewer software. Network maps of the authors and their affiliated institutions in the included studies were constructed and visualized, and clusters for each major node were identified. In addition, the latest research keywords were visualized using an overlay visualization function. Results The field of pediatric acupuncture research has shown a 20.5-fold quantitative increase in the number of publications over the past 30 years (1991 - 2023). In the field of pediatric acupuncture research, the United States has the highest productivity and influence, and South Korea ranked 7th in productivity and 10th in influence. Through keyword analysis in the field of pediatric acupuncture research, four clusters were identified. Pain management, use in pediatric oncology, and use in postoperative management were identified as important clinical topics. There is a lack of exchange among researchers in the field of pediatric acupuncture. Conclusions Pediatric acupuncture research continues to show quantitative growth and western countries have shown high productivity and influence in this field. In this study, the major keywords in the field of pediatric acupuncture research were identified, and the results can be used to establish the research direction of the Korean medicine community.

• 한국근적외분광분석학회:학술대회논문집
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• 한국근적외분광분석학회 2001년도 NIR-2001
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• pp.4114-4114
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• 2001

For the quality control of tablets several parameters have to be checked. The most important one is the content of an active ingredient which has to match a narrow range around the designated content. The only useful measurement mode is transmission which provides information of the complete tablet. A measurement in diffuse reflectance would register only the surface which is useless especially in case of a coated tablet. In this work tablets for a clinical study (placebo/verum studies) with very low concentrations of the active ingredient were measured. The concentration range was 0 to 6 mg with a total weight of the tablets of 105 mg, leading to a highest concentration of the active component of 5.7% by weight. Especially the spectroscopic distinction between the placebo and the low dosage forms with 0.25 and 0.5 mg active agent requires an extraordinarily accurate sampling technique. Using the VECTOR 22/N-T in transmission mode allows the collection of the information from the complete tablets. A quantitative PLS-model with transmission spectra from the tablets described above shows that the active substance can be predicted with a RMSECV (root mean square error of cross validation) of 0.04% absolute for this special application. The results are compared with those of measurements in diffuse reflectance using different accessories.

• 디지털산업정보학회논문지
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• 제19권4호
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• pp.97-115
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• 2023

In South Korea, chronic kidney disease(CKD) impacts around 4.6 million adults, leading to a high reliance on hemodialysis. For effective dialysis, vascular access is crucial, with decisions about vascular surgeries often made during dialysis sessions. Anticipating these needs could improve dialysis quality and patient comfort. This study investigates the use of Artificial Intelligence(AI) to predict the timing of surgeries for dialysis vessels, an area not extensively researched. We've developed an AI algorithm using predictive maintenance methods, transitioning from machine learning to a more advanced deep learning approach with Long Short-Term Memory(LSTM) models. The algorithm processes variables such as venous pressure, blood flow, and patient age, demonstrating high effectiveness with metrics exceeding 0.91. By shortening the data collection intervals, a more refined model can be obtained. Implementing this AI in clinical practice could notably enhance patient experience and the quality of medical services in dialysis, marking a significant advancement in the treatment of CKD.

• 융합정보논문지
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• 제12권5호
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• pp.21-31
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• 2022

본 연구는 임상간호사의 투약안전역량에 영향을 미치는 요인을 규명하고자 시도되었다. 자료의 수집은 상급종합병원 두 곳에 재직하고 있는 154명의 간호사를 대상으로 진행하였다. 자료의 분석은 SPSS 26.0 프로그램으로 t-검정, ANOVA, 상관관계, 단계적 다중회귀분석을 하였다. 연구결과 투약안전역량은 문제해결능력과 자기효능감과 유의한 상관관계가 있었다. 자기효능감, 문제해결능력, 근무형태, 현부서 근무경력 순으로 투약안전역량에 영향을 미치는 것으로 나타났고 이들 변수는 전체변량의 64.7%의 설명력을 가졌다. 따라서 임상간호사의 투약안전역량을 증진시키기 위해서는 무엇보다도 자기효능감과 문제해결능력을 증진시키기 위한 프로그램이 개발 될 필요가 있겠다.

• 융합정보논문지
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• 제10권10호
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• pp.236-245
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• 2020

본 연구의 목적은 임상치과위생사의 조직몰입을 증진하고자 정서적 소진, 적응유연성, 직무착근도와 조직몰입과의 관련성을 파악함으로써 효과적인 치과의료전달체계 및 인력관리에 기초자료를 제공하고자 시도되었다. 자료 수집은 2019년 11월 11일부터 12월 30일까지 대전·충청·전라 지역에 근무하는 치과위생사를 편의표본추출 하였으며, 자기기입식 설문법을 사용하였다. 조직몰입과 적응유연성, 직무착근도는 양의 상관관계를 나타냈고, 정서적 소진은 음의 상관관계를 나타냈으며, 정서적 소진과 적응유연성, 직무착근도는 음의 상관관계를 나타냈고, 적응유연성과 직무착근도는 양의 상관관계를 나타냈다. 조직몰입에 영향 요인은 정서적 소진, 적응유연성, 직무착근도 순으로 높게 나타났다. 이에 임상치과위생사의 조직몰입을 효율적으로 유지 및 관리하기 위한 프로그램 탐구 시 정서적 소진, 적응유연성, 직무착근도를 포함한 맞춤형 중재전략이 함께 고려될 필요가 있을 것으로 생각된다.

• 대한통합의학회지
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• 제11권4호
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• pp.157-166
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• 2023

Purpose : The purposes of this study were to determine the relationships of communication skills with smartphone addiction and self-efficacy before clinical practice training among nursing students and to provide basic data for developing and verifying the effectiveness of an intervention program for improving nursing students' communication skills. Methods : This study targeted those who obtained consent to collect data explained the purpose and procedure of the study for the first and second graders of the nursing department at one university located in B city. The data collection period was from April 24 to May 13, 2023. A total of 207 questionnaire responses were included in the analysis. The collected data were analyzed using t-tests and analysis of variance in the SPSS/Win 230 program. The results were reported as real numbers, percentages, mean values, and standard deviations. The correlations between the variables were analyzed using the Pearson correlation coefficient. Results : Smartphone addiction according to the general characteristics of the study subjects showed significant differences in 'residence type' (F=2.91, p=.035) and 'average smartphone usage time' (F=20.15, p=.000). It seemed. self-efficacy was determined by 'age' (F=2.74, p=.045), 'subjective academic level' (F=7.71, p=.001), and 'average smartphone usage time' (F=3.96, p=.009) showed a significant difference. Communication skills showed a significant difference in 'average smartphone usage time' (F=3.83, p=.011). The correlation between the variables of the study subjects showed that self-efficacy was negatively correlated with smartphone addiction (r=-.42, p<.001), and communication ability was positively correlated with self-efficacy. It was found that (r=.55, p<.001). 15) Conclusion : On the basis of the study results, the higher the nursing students' smartphone addiction, the lower their self-efficacy, and the higher their communication ability, the higher their self-efficacy. Therefore, intervention research is necessary to develop interventions for preventing smartphone addiction and increasing communication ability among nursing students.