• Korean Journal of Clinical Pharmacy
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• v.21 no.2
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• pp.170-181
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• 2011

Purpose: There is considerable variability in rates of hospitalization for patients with community-acquired pneumonia (CAP) in part because of physicians' uncertainty in assessing the severity of illness at presentation. The purpose of the study was to examine the current treatment patterns and factors influencing the Pneumonia Severity Index (PSI) and clinical outcomes in the patient with CAP. Method: The retrospective data collection of the patients with CAP was conducted and the data were reviewed. The collected data included demographic, clinical, laboratory and microbiological medical information. All patients were stratified into three risk groups according to PSI: low risk (PSI score I-II), moderate risk (III) and high risk (IV-V) groups. The examined treatment patterns were the appropriateness of admissions, category of antibiotics used. The prognostic factors associated with PSI and clinical outcomes were examined. Results: One hundred and six patients' medical data were reviewed. The overall appropriateness of admissions was low presenting many of patients were admitted or intensely treated in the hospital despite of lower risk of prognosis and treated with intravenous antibiotics instead of oral fluoroquinolones. Primary pneumonia pathogens were Klebsiella pneumoniae (27%) and Streptococcus pneumoniae (21.6%). Mean LOS was 8.5 days and was significantly longer (10.0days) (p<0.001) in high risk group. The patients with age >65 (p<0.001), diabetes mellitus (p<0.001), mental alteration (p<0.001), and/or $PaO_2$ <60 mmHg (p<0.001) had a tendency to have higher PSI. The prognostic factors associated with longer LOS were age >65 years (p=0.008), mental status alteration (p<0.001), dyspnea (p=0.002) and PSI score (p=0.001). The prognostic factors associated with mortality were congestive heart failure (p=0.038), systolic blood pressure <90 mmHg (p=0.002) and arterial pH <7.35 (p=0.013). Conclusion: Most of patients were found to over-utilize medical service according to appropriateness of admissions. The elderly, mentally altered patients with low $PaO_2$ had higher PSI score with increased risk of LOS. The mortality could be increased in the patient with disease state of congestive heart failure, high blood pressure, and/or acidosis.

• Annals of Clinical Neurophysiology
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• v.13 no.2
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• pp.71-79
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• 2011

Geographical differences in the incidence of amyotrophic lateral sclerosis (ALS) have been reported, and there are still many unresolved problems. The incidence as well as epidemiologic data of ALS is not known in Korea. Web-based multicenter registry of ALS, the Korean ALS registry, was established at January, 2011. The aim of "the Korean ALS registry" is the following: (1) to establish a database for the prospective collection of epidemiological information; (2) to assess the incidence and prevalence; (3) to find the temporal and geographic trends in the disease; (4) to define the full clinical spectrum of the disease; (5) to develop treatment guideline based on the database.

• Korean Journal of Clinical Laboratory Science
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• v.38 no.3
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• pp.147-151
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• 2006

Although various automated CBC analyzers with different WBC analytical principles were consequently introduced to clinical laboratory, the specific information concerning the suitability or unsuitability of aging samples is scarce. For this reason, we studied the effect of storage duration and temperature on CBC parameter in SE-9000 (SYSMEX Medical Electronics Co., Ltd., Kobe, Japan), automated CBC analyzer. We tested 32 K3-EDTA specimens with SE-9000 during 72 hours. Specimens were kept at room temperature (RT) and refrigerated and were analyzed at 0 hr, 4 hr, 8 hr, 24 hr, 48 hr and 72 hr after the collection of the specimens. The percentage changes from initial value for each parameters were calculated. Among the CBC parameters, hemoglobin, red blood cell count, mean corpuscular hemoglobin and platelets were stable for the study period at both temperatures. The mean corpuscular volume (MCV), hematocrit (Hct) and red cell distribution (RDW) increased and the mean corpuscular hemoglobin concentration (MCHC) decreased over time at room temperature. These parameters were stable when refrigerated. The leukocyte count was stable during 72hr at RT and when refrigerated. At room temperature, the relative percentages of neutrophils tend to increase, whereas those of lymphocyte and monocytes tend to decrease after 48 hours. When refrigerated, those of neutrophils and monocytes tend to increase, whereas those of lymphocytes tend to decreased over time. CBC parameters of refrigerated specimen were reliable for 72 hr for the exception of differential count from 24 hr but many CBC parameters, such as MCV, Hct, MCHC, RDW and differential count of leukocyte of blood stored at room temperature for 24 hr were unreliable.

• Journal of Internet Computing and Services
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• v.22 no.1
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• pp.89-98
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• 2021

Community-acquired pneumonia (CAP) is a major risk factor of mortality in chronic obstructive pulmonary disease (COPD). Streptococcus pneumoniae (colloquially known as pneumococcus) is one of important pathogens of CAP in patients with COPD. Preventive interventions for pneumonia include pneumococcal and influenza vaccinations. A prospective, cohort study has been performed to investigate the protective effects of pneumococcal and influenza vaccinations on the severity of community-acquired pneumonia requring hospital admission in patients with COPD. Seven university-affiliated hospitals in Korea have participated in the study. The aim of this study was to construct an online registration system for the multi-institutional researchers that facilitates efficient collection and management of COPD patient data. This study has presented three basic strategies-accurate data input, convenient data completion, and real-time data management-to supplement the demerits of existing offline clinical study. The proposed online registration system has already been applied to a multi-institutional clinical study and was acknowledged for its high performance.

• The Journal of Pediatrics of Korean Medicine
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• v.38 no.1
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• pp.10-22
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• 2024

Objectives This bibliometric analysis aimed to determine the status of pediatric acupuncture research. Methods Relevant bibliographic information up to January 9, 2024, was collected through searches in the Web of Science Core Collection. Bibliographic information was preprocessed for data analysis and analyzed using VOSviewer software. Network maps of the authors and their affiliated institutions in the included studies were constructed and visualized, and clusters for each major node were identified. In addition, the latest research keywords were visualized using an overlay visualization function. Results The field of pediatric acupuncture research has shown a 20.5-fold quantitative increase in the number of publications over the past 30 years (1991 - 2023). In the field of pediatric acupuncture research, the United States has the highest productivity and influence, and South Korea ranked 7th in productivity and 10th in influence. Through keyword analysis in the field of pediatric acupuncture research, four clusters were identified. Pain management, use in pediatric oncology, and use in postoperative management were identified as important clinical topics. There is a lack of exchange among researchers in the field of pediatric acupuncture. Conclusions Pediatric acupuncture research continues to show quantitative growth and western countries have shown high productivity and influence in this field. In this study, the major keywords in the field of pediatric acupuncture research were identified, and the results can be used to establish the research direction of the Korean medicine community.

• Proceedings of the Korean Society of Near Infrared Spectroscopy Conference
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• 2001.06a
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• pp.4114-4114
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• 2001

For the quality control of tablets several parameters have to be checked. The most important one is the content of an active ingredient which has to match a narrow range around the designated content. The only useful measurement mode is transmission which provides information of the complete tablet. A measurement in diffuse reflectance would register only the surface which is useless especially in case of a coated tablet. In this work tablets for a clinical study (placebo/verum studies) with very low concentrations of the active ingredient were measured. The concentration range was 0 to 6 mg with a total weight of the tablets of 105 mg, leading to a highest concentration of the active component of 5.7% by weight. Especially the spectroscopic distinction between the placebo and the low dosage forms with 0.25 and 0.5 mg active agent requires an extraordinarily accurate sampling technique. Using the VECTOR 22/N-T in transmission mode allows the collection of the information from the complete tablets. A quantitative PLS-model with transmission spectra from the tablets described above shows that the active substance can be predicted with a RMSECV (root mean square error of cross validation) of 0.04% absolute for this special application. The results are compared with those of measurements in diffuse reflectance using different accessories.

• Journal of Convergence for Information Technology
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• v.12 no.5
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• pp.21-31
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• 2022

This study attempted to identify factors affecting the clinical nurse's medication safety competence. Data collection was conducted with 154 nurses working in two tertiary general hospitals. Data were analyzed using by t-test, ANOVA, Pearson correlation coefficient, and stepwise multiple regression analysis with SPSS 26.0 program. As a result of the study, medication safety competence had a statistically significant correlation with problem-solving ability and self-efficacy. The factors influencing medication safety competences were in order of self-efficacy, problem-solving ability, work pattern, and current site work experience, which together accounted for 64.7% of the total variance. Therefore, in order to improve the clinical nurse's medication safety competences, prioritizing the development of a program to enhance self-efficacy and problem-solving ability is required.

• Journal of Korea Society of Digital Industry and Information Management
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• v.19 no.4
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• pp.97-115
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• 2023

In South Korea, chronic kidney disease(CKD) impacts around 4.6 million adults, leading to a high reliance on hemodialysis. For effective dialysis, vascular access is crucial, with decisions about vascular surgeries often made during dialysis sessions. Anticipating these needs could improve dialysis quality and patient comfort. This study investigates the use of Artificial Intelligence(AI) to predict the timing of surgeries for dialysis vessels, an area not extensively researched. We've developed an AI algorithm using predictive maintenance methods, transitioning from machine learning to a more advanced deep learning approach with Long Short-Term Memory(LSTM) models. The algorithm processes variables such as venous pressure, blood flow, and patient age, demonstrating high effectiveness with metrics exceeding 0.91. By shortening the data collection intervals, a more refined model can be obtained. Implementing this AI in clinical practice could notably enhance patient experience and the quality of medical services in dialysis, marking a significant advancement in the treatment of CKD.

• Journal of Convergence for Information Technology
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• v.10 no.10
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• pp.236-245
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• 2020

The purpose of this study was to determine the associations among emotional burnout, resilience, job embeddedness, and organizational commitment, provide basic data for an effective dental care delivery system and manpower management, and promote organizational commitment in clinical dental hygienists. For data collection, convenience sampling was performed among dental hygienists working in Daejeon and Chungcheong and Jeolla Provinces from November 11 to December 30, 2019, and a self-administered questionnaire was used. Organizational commitment was positively correlated with resilience and job embeddedness and was negatively correlated with emotional burnout; emotional burnout was negatively correlated with resilience and job embeddedness; and resilience was positively correlated with job embeddedness. The factor most significantly affecting organizational commitment was emotional burnout, followed by resilience and job embeddedness. It is therefore necessary to give another consideration to a customized intervention strategy, which involves emotional burnout, resilience, and job embeddedness, in exploring a program that helps clinical dental hygienists maintain and manage organizational commitment efficiently.

• Journal of The Korean Society of Integrative Medicine
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• v.11 no.4
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• pp.157-166
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• 2023

Purpose : The purposes of this study were to determine the relationships of communication skills with smartphone addiction and self-efficacy before clinical practice training among nursing students and to provide basic data for developing and verifying the effectiveness of an intervention program for improving nursing students' communication skills. Methods : This study targeted those who obtained consent to collect data explained the purpose and procedure of the study for the first and second graders of the nursing department at one university located in B city. The data collection period was from April 24 to May 13, 2023. A total of 207 questionnaire responses were included in the analysis. The collected data were analyzed using t-tests and analysis of variance in the SPSS/Win 230 program. The results were reported as real numbers, percentages, mean values, and standard deviations. The correlations between the variables were analyzed using the Pearson correlation coefficient. Results : Smartphone addiction according to the general characteristics of the study subjects showed significant differences in 'residence type' (F=2.91, p=.035) and 'average smartphone usage time' (F=20.15, p=.000). It seemed. self-efficacy was determined by 'age' (F=2.74, p=.045), 'subjective academic level' (F=7.71, p=.001), and 'average smartphone usage time' (F=3.96, p=.009) showed a significant difference. Communication skills showed a significant difference in 'average smartphone usage time' (F=3.83, p=.011). The correlation between the variables of the study subjects showed that self-efficacy was negatively correlated with smartphone addiction (r=-.42, p<.001), and communication ability was positively correlated with self-efficacy. It was found that (r=.55, p<.001). 15) Conclusion : On the basis of the study results, the higher the nursing students' smartphone addiction, the lower their self-efficacy, and the higher their communication ability, the higher their self-efficacy. Therefore, intervention research is necessary to develop interventions for preventing smartphone addiction and increasing communication ability among nursing students.