• Title/Summary/Keyword: Collaboration medicine

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XRCC1 Gene Polymorphisms and Breast Cancer Risk: A Systematic Review and Meta-analysis Study

  • Moghaddam, Ali Sanjari;Nazarzadeh, Milad;Moghaddam, Hossein Sanjari;Bidel, Zeinab;Karamatinia, Aliasghar;Darvish, Hossein;Jarrahi, Alireza Mosavi
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.sup3
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    • pp.323-335
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    • 2016
  • Breast cancer risk assessment has developed during years and evaluation of genetic factor affecting risk of breast cancer is an important component of this risk assessment. The aim of this meta-analysis was to investigate the role of XRCC1 polymorphisms (Arg194Trp, Arg280His and Arg399Gln) in risk of breast cancer among different population and categories of menopausal status.PubMed, Medline, Web of Science, and PubMed Central were systematically searched to identify studies evaluating association between breast cancer and XRCC1 gene polymorphisms (Arg194Trp, Arg280His and Arg399Gln). Two authors independently extracted required information. Odds Ratios were pooled for four genetic inheritance models using both fixed and the DerSimonian and Laird random-effect models. Egger's test and contour-enhanced funnel plot was used to evaluate publication bias and small study effect. Additional subgroup analysis was performed for menopausal status, ethnicity, and source of controls. After evaluation and applying inclusion criteria on extracted studies, fifty three studies were included in this meta-analysis. For polymorphisms of Arg194Trp and Arg280His, no significant association was observed in all genetic models. Arg194Trp had a protective effect in post-menopausal status only in homozygote model (OR=0.57 [0.37-0.88]). Arg399Gln showed significant association with breast cancer in homozygote (OR=1.21 [1.10-1.34]), dominant (OR=1.09 [1.03-1.15]) and recessive (OR=1.21 [1.09- 1.35]) genetic models. Arg399Gln was associated with higher risk in post-menopausal status for homozygote and heterozygote models. Our findings suggest that XRCC1 gene polymorphisms modify breast cancer risk in different populations and different categories of menopausal status.

Awareness of Asbestos and Action Plans for Its Exposure can Help Lives Exposed to Asbestos

  • Lee, Hu-Jang;Park, Eun-Kee;Wilson, Donald;Tutkun, Engin;Oak, Chulho
    • Safety and Health at Work
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    • v.4 no.2
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    • pp.84-86
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    • 2013
  • Despite the fact that asbestos is a known carcinogen to humans, it is still used in industrialized countries, especially Asian countries. The global incidence of asbestos-related diseases (ARDs) due to the past use of asbestos, continues to increase, although many countries have adopted a total ban on asbestos use. The implementation of effective strategies to eliminate ARDs is therefore an important challenge in Asia, where asbestos is still mined and consumed. Collaborative efforts and strategies at the local and international levels are vital, in the pursuit toward the elimination of ARDs in this region.

Future Management Strategies for Zoonoses Based on One Health (원헬스 기반 인수공통감염병의 미래 관리 전략)

  • Lee, Kwan
    • Journal of agricultural medicine and community health
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    • v.44 no.1
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    • pp.39-42
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    • 2019
  • Zoonoses are the diseases that are transmitted to human being from vertebrate animals either from livestock animals or from wildlife. Recently, zoonoses are increasingly common as a result of incremental human-animal contact. Propagative infections in wild animals and livestock are transmitted to human beings who are encountered with them. In general, wild animals can transmit infectious agents to livestock, and then livestock further transmit them to human being is a simple model of on how zoonotic diseases get transmitted to human being. This model emphasizes the importance of early detection of zoonoses by surveillance at its incipient stage. Cooperation between the respective ministries plays an important role in the identification of zoonoses and planning for the formulation of better preventive and control policy and strategy. We will be able to predict the occurrence of zoonotic diseases in human on the basis of disease trends in wildlife and livestock once when we obtain the surveillance data and data generated by respective ministries through sound cooperation and collaboration.

A Study in the Influence of The Treasured Mirror of Eastern Medicine (Donguibogam) upon the Koryo Medicine in North Korea (최근 북한 고려 의학에 반영된 『동의보감』 연구)

  • Zhang, Zili;Jin, Jun
    • Journal of Korean Medical classics
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    • v.31 no.3
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    • pp.99-107
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    • 2018
  • Objectives: This article aims to clarify the understanding and publication status of both The Treasured Mirror of Eastern Medicine (Donguibogam) and some of its recent research progress made in North Korea, as well as their influences upon the academic of Koryo medicine in North Korea. Methods: Analysis was carried out based on various reference books, dictionaries and Korean translation of Donguibogam (1964 Ver.) published by North Korea, as well as the North Korean quarterly medical journal, Koryo Medicine. Results: The academic of Koryo medicine in North Korea regards Donguibogam, a Korean medical classic as it was written by native Korean physicians and it became an important ground material for basic research and clinical study. Various terminologies used in the original version of Donguibogam were defined as unscientific and superstitious by North Korean academics, which were then subsequently removed from the Korean translation of Donguibogam (1964 Ver.) published by North Korea. Therefore, this version cannot be seen as a complete edition of Donguibogam. Conclusions: The Donguibogam is known as one of the 'three major books of Koryo medicine' in North Korea. As a treasure of East-Asian traditional medical classic, Donguibogam is expected to become the medium for a closer research collaboration between the North and South Koreas including China in the future.

Current Trend of Mibyeong Health Policy and Service in China through Investigation Activity of Mibyeong Technology -Report of China Technology Research Group- (현지 기술 조사활동을 통한 중국의 미병 정책 및 의료서비스 최신 동향 보고)

  • Lee, Jae-Chul;Kim, Dong-Soo;Jang, Eun-Su
    • Journal of Society of Preventive Korean Medicine
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    • v.17 no.1
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    • pp.137-147
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    • 2013
  • Objectives : This study aims to report current trend of Mibyeong health policy and service in China from interview of China Technology Research Group. Methods : China Technology Research Group visited Guanganmen hospital, Yanhuang Dongfang Company, Xinjingzhen health center, and Shanghai Shuguang hospital. With an interpreter, We had interviews about Mibyeong health service and policy trend, medical instrument, and research issue. Results :Mibyeong health service was performed based on KY3H system and collaboration with traditional Chinese medicine hospital. Mibyeong health service consists of diagnosis with nine constitutional type, health guide and preventive treatment. Community health center also provide Mibyeong health service, with cooperative treatment of traditional Chinese medicine and western medicine. China's Mibyeong health policy is established by Top-down decision, even though there is not enough evidence for providing health service to consumer. Through constitutional diagnosis, examinations, and treatment, huge data have been stacked; however, assessment and research based on these data are not processed well. Cooperative treatment of traditional Chinese medicine and western medicine is widely provided to patients, and their works are relatively well classified. Conclusions : China plays leading role in Mibyeong service and it seems to be developed more than Korea's. Further study is necessary to establish Mibyeong policy and health service in Korea.

A Policy Proposal for the Korean Collaboration of Eastern and Western Medicine according to a model of the Chinese Integrative Medicine (중국(中國) 중서의결합(中西醫結合)모형에 따른 한국(韓國)의 한양방협진(韓洋方協診) 정책(政策) 제언(提言))

  • Park, Jeong-Seok;Shin, Byung-Chul;Kim, Chun-Bae;Jeong, Tae-Young;Lee, Yeon-Weol;Cho, Chong-Kwan;Yoo, Hwa-Seung
    • Journal of Haehwa Medicine
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    • v.19 no.1
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    • pp.1-7
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    • 2010
  • Melasma is a common disorder that causes dark colored patches. It generally causes brown spots on the face, especially on the forehead, cheeks, and upper lips. The pattern of patches has bilateral symmetry in yellowish-brown to gray-brown colors. It is much more common in women than in men. Melasma is considered to be caused by environmental and physical constitutional factors and often occurs when a woman's hormone changes by pregnancy or the use of oral contraceptive pills. It is important to combine oriental medicine and Sasang constitutional medicine for treatment of Melasma. Normal treatment of Melasma includes warming oneself, removal of the emotional stress factors, and good nutrition.

Future of Preventive Medicine Education in Korea: Hopes and Challenges (우리나라 예방의학교육의 미래: 희망과 도전)

  • Meng, Kwang-Ho
    • Journal of Preventive Medicine and Public Health
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    • v.39 no.1
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    • pp.7-12
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    • 2006
  • Throughout the century, based on the precedent set by Flexner in the United States, almost every subsequent report on the reform of medical education has pointed out the need for more prevention-oriented teaching in the curriculum. This has been particularly so in countries like Korea where the basic public health services have been so important for the improvement of health of the people. And, in fact, preventive medicine and public health have contributed a great deal to the prevention of communicable diseases and prolongation of life expectancy. Recently, however, along with the educational reform that emphasizing the interdisciplinary teaching, integration of basic science and clinical education, and centralization of responsibility for the medical education curriculum, concerns are being voiced by preventive medicine educators. These concerns are primarily centered around the fear that the implementation of interdisciplinary, centrally administered courses would result in a weakening of content and teaching expertise as well as a loss of departmental power and control. This paper foresees that preventive medicine and public health will be more important in Korea in the future and proposes that preventive medicine educators will have to step forward and turn the challenges of curricula restructuring into opportunities to expand the role of preventive medicine in the curricula of their institutions.

Clinical Observation on 2 Cases of Acute Disseminated Encephalomyelitis(ADEM) (급성 파종성 뇌척수염 환자의 치험 2례)

  • Koo, Beom-Mo;Lee, Kyung-Yun;Yang, Dong-Ho;Kim, Sung-Keun;Lim, Chang-Sun;Park, Young-Chul;Yi, Joo-Il;Kim, Joo-Young
    • Journal of Acupuncture Research
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    • v.25 no.3
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    • pp.189-196
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    • 2008
  • Objectives : The purpose of this case is to report the improvement of the patients with Acute Disseminated Encephalomyelitis(ADEM) after acupuncture, moxibustion, and herbal medicine. Methods : We treated the patients with acupuncture, moxibustion and herbal medication. Results : We treated two cases of Acute Disseminated Encephalomyelitis(ADEM). These two patients improved significantly through treatment, acupuncture, moxibustion, herbal medicine, and western medicine. Conclusions : In Acute Disseminated Encephalomyelitis (ADEM), the initial diagnosis is important, and through a collaboration of Western and Korean medicine, we were able to achieve meaningful treatment results.

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The values evident in strengthening community actions: health plus happiness plus projects in Gyeongsangnam-Do (주민주도형 건강증진전략이 수반하는 가치: 경상남도 건강플러스 행복플러스 사업을 중심으로)

  • Kim, Jang-Rak;Jeong, Baekgeun;Park, Ki-Soo;Kang, Yune-Sik
    • Korean Journal of Health Education and Promotion
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    • v.32 no.4
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    • pp.13-23
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    • 2015
  • Objectives: his study was performed to examine whether a community organization strategy had been driven by core values explicit in Ottawa Charter and to give some suggestions for using values in health promotion practice in Korea. Methods: We searched literature online with key words of 'values', 'health promotion', and/or 'Ottawa Charter', etc, and reviewed published papers on design, implementation, and evaluation of Health Plus Happiness Plus Projects in Gyeongsangnam-Do, a community organization strategy. Results: Evident core values since Ottawa Charter had been holistic definition of health, empowerment, community participation, addressing the impact of broader determinants of health, reducing social inequities and injustice, and intersectoral collaboration. A community organization strategy was good at realization of most values. Some ways for value-driven health promotion practice were suggested. Conclusions: More discussion and debate on values in health promotion are needed in Korea.

Human and Society-Centered Learning Outcomes in Basic Medical Education (사람과 사회 중심의 기본의학 학습성과)

  • Kim, Dae Hyun
    • Korean Medical Education Review
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    • v.18 no.3
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    • pp.150-155
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    • 2016
  • Learning objectives for human and society-centered basic medical education to improve physicians' ability to practice in a Korean context were developed by the Korean Association of Medical Colleges in 2015-2016. The task-force committee identified eight domains for medical practitioners: human illness, reflection and self-improvement, patient safety, communication and collaboration, medical ethics, legal issues, social accountability, and professionalism. A total of 172 enabling learning outcomes and 42 terminal learning outcomes were identified by the workshop. The workshop members were representatives from 41 medical schools, the Korean Medical Association, and a scientific group (medical ethics, legal issues, and medical communication). The curriculum for "medical humanity and social medicine" was first published in 2007. The human and society-centered learning objectives that were developed will be revised annually.