• 한국소성가공학회:학술대회논문집
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• 한국소성가공학회 2006년도 춘계학술대회 논문집
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• pp.399-402
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• 2006

The outer race of CV(constant velocity) joint is an important load-supporting automotive part, which transmits torque between the transmission gear box and driving wheel. The outer race is difficult to forge because its shape is very complicated and the required dimensional tolerances are very small. Traditional warm and cold forging methods have their own limitations to produce such a complex shaped part; warm forging requires complex system with relatively higher manufacturing cost, while cold forging is not applicable to materials with limited formability. Therefore, multistage forging may be advantageous to produce complex shaped parts. In order to build a multistage forging system, it is necessary to characterize mechanical properties in response to system design parameters such as temperature, forging speed and reduction. For the analysis of formability of multistage forging process, finite element method(FEM) has been used for the process analysis. As a model case, a constant velocity (CV) joint forging process is analyzed by FEM, since CV joint has a complex shape and also its required dimensional tolerances are very tight. The data acquired by FEM is compared with operational forging data obtained from an industrial production line. Based on this comparative analysis, multistage forging process for CV joints is proposed.

• KIEAE Journal
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• 제13권2호
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• pp.3-12
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• 2013

Recently, New Han-ok is in prevail because it has many good qualities as a dwelling. But the New Han-ok dwellers' needs and satisfaction ratio on their houses are not investigated yet. So, surveys on satisfaction ratio for New Han-ok were carried out to know New Han-ok's existing conditions and inhabitant's responses on New Han-ok dwellings. Followings are results. 1) Dwellers response that it is cool in summer and it is cold in winter. So, design and construction method against cold is needed for New Han-ok. 2) Window is the most picking element of New Han-ok for house improvement. 3) Window opening is main control method for cooling in summer. Warming sources in winter are various such as electricity, gas, oil, wood, etc. 4) PVC window structure and glasses were used for New Han-ok's window system as well as wooden window structure and Han-gi. 5) Interviewees are generally satisfied with New Han-ok's exterior view and inner spaces. Almost no humidifier is used. These results could be used for improvement of Han-ok and basic material for New Han-ok design.

• Nuclear Engineering and Technology
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• 제29권3호
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• pp.229-239
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• 1997

To investigate the realistic behavior of mass and energy release and resultant containment response during large break Loss of Coolant accident (LOCA), analyses are performed for Yonggwang (YGN) 3&4 nuclear power plants by using a merged version of RELAP5/CONTEMPT4 computer code. Comparative analyses by using conservative design computer codes are also peformed. The break types analyzed are the double-ended guillotine breaks at the cold leg and hot leg. The design analysis resulted in containment peak pressure during post-blowdown phase for the cold leg break. However, the RELAP5/CONTEMPT4 analyses show that the containment pressure has a peak during blowdown phase, thereafter it decreases monotonously without the second port-blowdown peak. For the hot leg break, revised design analysis shows much lower pressure than that reported in YGN 3&4 final safety analysis report. The RELAP5/CONTEMPT4 analysis shoos similar trend and confirmed that the bypass flow through the broken loop steam generator during post-blowdown is negligibly small compared to that of cold leg break. The low pressure and temperature predicted tv realistic analysis presented in this paper suggest that the design analysis methodology contains substantial margin and it can be improved to provide benefit in investment protection, such as, relaxing plant technical specifications and reducing containment design pressure.

• 한국의류산업학회지
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• 제12권4호
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• pp.513-522
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• 2010

The aim of this study is to investigate the actual state for the development of the thermally comfortable uniform for workers on a low temperature storage. Observation, interview and survey were executed focusing on the environment, clothing, and human factors which have effects on the comfort of workers. Of 400 distributed, 253 questionnaires were analyzed through descriptives, frequency, ANOVA, t-test, multi-response analysis, correlation analysis with SPSS 12.0. The results are following. Coming and going between a selling area and cold storages, the workers showed to experience a big temperature gap. They indicated to feel cold on face and hands which were not covered by clothing and have got sick because of low temperature. The workers wanted the uniform made of functional fabrics, especially heat insulation fabrics. Female workers rather than male workers, the older, and the longer their working period were, the more uncomfortable they revealed to feel. The workers who works on the daily products part or mainly on the freezer appeared to feel cold more than any other workers. In conclusion, it was found that the uniform which consider steady state and unsteady state heat transfer together must be developed.

• Earthquakes and Structures
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• 제4권6호
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• pp.629-647
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• 2013

Loading protocols have been developed for quasi-static cyclic testing of structures and components. However, it is uncertain if protocols developed for conditions of intense ground shaking in regions of high seismicity would also be applicable to regions of low-moderate seismicity that are remote from the tectonic plate boundaries. This study presents a methodology for developing a quasi-static cyclic displacement loading protocol for experimental bracing evaluation of cold-formed steel stud shear walls. Simulations presented in the paper were based on conditions of moderate ground shaking (in Australia). The methodologies presented are generic in nature and can be applied to other regions of similar seismicity conditions (which include many parts of China, Korea, India and Malaysia). Numerous response time histories including both linear and nonlinear analyses have been generated for selected earthquake scenarios and site classes. Rain-flow cycle counting method has been used for determining the number of cycles at various ranges of normalized displacement amplitude. It is found that the number of displacement cycles of the loading protocol increases with increasing intensity of ground shaking (associated with a longer return period).

• 한국의사학회지
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• 제34권2호
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• pp.25-43
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• 2021

Among the ancient ideas of East Asia, there is a myth about the symbol of the Four Gods who commands all directions in the east, south, west, and north, and this is also reflected in the medical field. However, although there is discussion about Qinglong Decoction (青龍湯), Baihu Decoction (白虎湯) and Xuanwu Decoction (玄武湯) in the 『Shanghan Lun (傷寒論)』, there is no content focusing on Zhuniao decoction (朱鳥湯). Considering the consistent perspective of 『Shanghan Lun』, which recognizes the disease-syndrome and seeks prescriptions based on yin and yang thinking, this is very unusual. Therefore, in this study, it was revealed that the concept of 'Sishen Decoction (四神湯)' itself was a concept that emerged when the authors of 『Shanghan Lun』 established the 'eight-principles syndrome differentiation (八綱辨證)' system in their recognition and response to diseases-syndromes. Based on this, I considered the following possibilities: They were able to present Qinglong decoction, Baihu Decoction and Xuanwu decoction, as appropriate prescriptions for 'exterior cold excess syndrome (表寒實證)', 'interior heat deficiency syndrome (裏熱虛證)', and 'interior cold deficiency syndrome (裏熱實證)'. However, it is possible that the name of the prescription 'Zhuniao decoction' was not intentionally used, because it was not possible to provide an appropriate prescription for 'exterior cold excess syndrome (表熱實證)'.

• 대한한의학회지
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• 제28권3호통권71호
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• pp.261-272
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• 2007

Objectives : This study was conducted to determine the analgesic effect of Acanthopanax sessiliflorus using the model of neuropathic pain and formalin-induced pain. Methods : A model of neuropathic pain was made by injuring the tibial nerve and sural nerve while the common peroneal nerve was maintained. After 2 weeks, the Acanthopanax sessiliflorus was orally administered to rats. The author performed behavioral teststo try out mechanical allodynia using von frey filament and cold allodynia using acetone, which are calculated by counting withdrawal response on foot. Thirty minutes after the Acanthopanax sessiliflorus injection in the abdominal cavity, the formalin test was performed. 2% formalin in a volume of $20{\mu}l$was injected subcutaneously into the plantar surface of the hindpaw with 26-G needle. To access formalin-induced pain behavior, paw licking time was measured every 5 min. Results : The Acanthopanax sessiliflorus 400mg/10ml/kg group showed significant decrease the withdrawal response of mechanical allodynia using von frey filament in the 10min, 30min, 60min and 120min increments compared with the control group. There were no significant differences in each group in the withdrawal response of cold allodynia using acetone. The Acanthopanax sessiliflorus group showed significant decrease in the formalin-induced pain behavior in the 15min, 20min and 25min increments compared with the control group. Conclusions : The Acanthopanax sessiliflorus may have a significant analgesic effect on the general pain as well as nerve injury pain.

• Korean Chemical Engineering Research
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• 제53권4호
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• pp.524-529
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• 2015

본 논문에서는 저온활성 protease의 생산을 최적화하기 위하여 극지 미생물인 Enterobacteriaceae sp. PAMC 25617의 반응표면분석법을 이용한 배지의 최적화를 수행하였다. One-factor-at-a-time 방법을 이용하여 yeast extract, TritonX-100이 protease의 생산에 영향을 미치는 주요인자인 것을 확인하였다. 물리적인 환경 요인으로 pH를 추가하여 반응표면분석 방법을 이용한 최대 protease 생산 농도를 갖는 각 인자들의 농도를 확인한 결과 5 g/L peptone, 3 g/L malt extract, 10 g/L $C_6H_{12}O_6$, 6.690 g/L yeast extract, 0.018 g/L TritonX-100의 농도에 pH 6.777의 조건에서 미생물을 배양하였을 경우, 최대 10.049 U/L의 protease가 생산될 수 있는 것으로 예측되었다. 실제 배양 결과 8.03 U/L의 protease가 얻어졌으며, 최적화 이전의 생산농도와 비교하여 150% 이상의 증가를 이루었다. 결과적으로 배지최적화를 통한 protease 생산량의 증가에 반응표면분석법의 적용이 유용하다는 것을 확인할 수 있는다. 이러한 결과로부터, 배지 최적화를 이용한 극지 미생물 유래 cold-adapted protease 생산량의 증가가 여러 산업 분야에서 유용하게 이용될 수 있을 것으로 생각된다.

• 대한한방내과학회지
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• 제41권4호
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• pp.553-562
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• 2020

Objective: To investigate the vasodilatory effect of Sipjeondaebo-tang by inhibiting RhoA activity in vascular cells during cold exposure. Methods: Human vascular endothelial cells and pericytes were pretreated with Sipjeondaebo-tang for 30 min, followed by incubation at 37 ℃ (control) or 25 ℃ (cold exposure) for 30 min. Activation of endothelin-1-mediated RhoA in pericytes was assessed by pretreating the cells with Sipjeondaebo-tang for 30 min, followed by incubation with endothelin-1 at 37 ℃ for 30 min. Western blotting was performed to measure the expression of active RhoA. Endothelin-1 and nitric oxide release from endothelial cells was examined with enzyme-linked immunosorbent assay kits. The formation of stress fibers and focal adhesion complexes was analyzed by immunocytochemistry. Results: Cold treatment activated RhoA in both pericytes and vascular endothelial cells, whereas Sipjeondaebo-tang treatment inhibited this activation. Sipjeondaebo-tang treatment also reversed the cold-mediated production of endothelin-1 and nitric oxide. Cold exposure promoted the formation of stress fibers and focal adhesion complexes by increasing the expression of phospho-focal adhesion complex kinase, whereas Sipjeondaebo-tang treatment suppressed this response. Conclusions: These findings suggested that Sipjeondaebo-tang inhibits cold-induced RhoA activation and its related pathway components, including endothelin-1 and nitric oxide, in vascular cells. Therefore, Sipjeondaebo-tang could be beneficial for the treatment of Raynaud's phenomenon.

• 미생물학회지
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• 제54권3호
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• pp.200-207
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• 2018

높은 염분 농도에서 glycine betaine은 Bacillus subtilis 안으로 유입되어 세포 생장이 지속될 수 있게 한다. 뿐만 아니라 최근 연구 결과에 따르면 저온에서도 glycine betaine이 세포 생장을 지속시키는 것으로 알려져 있다. 저온에서 Bacillus subtilis의 생장을 저해시키는 세포 대사 활동으로는 세포막 운송과 단백질 합성을 들 수 있다. 세포막 구조와 관련하여 저온에서 세포막 운송에 영향을 주는 유전자들로는 bkdR과 des가 있고, 단백질 합성 과정에서 RNA helicase 유전자인 ydbR과 yqfR들은 저온 민감성을 보인다. 따라서 Bacillus subtilis 저온 민감성 유전자 결손 세포들에 대한 glycine betaine의 효과를 조사하여 저온에서의 glycine betaine 생리적 기능에 대해 알아보고자 하였다. 이 결과 glycine betaine의 존재 유무에 따라 야생형 Bacillus subtilis와 ydbR과 yqfR 결손 균주의 저온생장에 큰 차이를 보였다($T_d$차이 190~686 min). 반면에 bkdR이나 des 결손균주의 경우에는 glycine betaine 존재 유무에 따라 차이를 보이지 않았다. Glycine betaine의 전구체인 choline으로 대치하여도 저온에서의 생장은 같은 결과를 보였다. Glycine betaine의 영향이 세포막 구조와 관련이 있는 유전자 bkdR과 des 결손균주에 미치는 영향이 적은 것을 알아보기 위해 세포막에 영향을 주는 세제의 효과를 조사하였다. Triton X-100과 N-lauryl sarcosine 세제에 의해 bkdR 결손 균주가 야생형에 비해 더 영향 받는 것을 확인하였고 이는 bkdR 결손이 저온에서 막 구조를 변형하여 glycine betaine의 투과에 영향을 미치는 것으로 보인다.