• Communications for Statistical Applications and Methods
• /
• v.20 no.6
• /
• pp.455-466
• /
• 2013

In nested case-control studies, the most common way to make inference under a proportional hazards model is the conditional logistic approach of Thomas (1977). Inclusion probability methods are more efficient than the conditional logistic approach of Thomas; however, the epidemiology research community has not accepted the methods as a replacement of the Thomas' method. This paper promotes the inverse probability weighting method originally proposed by Samuelsen (1997) in combination with an approximate jackknife standard error that can be easily computed using existing software. Simulation studies demonstrate that this approach yields valid type 1 errors and greater powers than the conditional logistic approach in nested case-control designs across various sample sizes and magnitudes of the hazard ratios. A generalization of the method is also made to incorporate additional matching and the stratified Cox model. The proposed method is illustrated with data from a cohort of children with Wilm's tumor to study the association between histological signatures and relapses.

• The Korean Journal of Applied Statistics
• /
• v.15 no.2
• /
• pp.323-336
• /
• 2002

In this paper we consider the modified continual reassessment method in which a cohort consists of three patients. Simulation has been a main research tool in the investigation of CRM. In this paper we propose complete enumeration as an alternative of simulation. Using new method we show that the expected toxicity rate at the MTD converges to the target toxicity rate well as the sample size increases.

• Journal of Advanced Navigation Technology
• /
• v.5 no.1
• /
• pp.1-10
• /
• 2001

Speech has a good characteristics of which car drivers busy to concern with miscellaneous operation can make use in convenient handling and manipulating of devices. By utilizing this, this works proposes a speaker verification method for protecting cars from being stolen and identifying a person trying to access critical on-line services. In this, continuant phonemes recognition which uses language information of speech and MLP(mult-layer perceptron) which has some advantages against previous stochastic methods are adopted. The recognition method, though, involves huge computation amount for learning, so it is somewhat difficult to adopt this in speaker verification application in which speakers should enroll themselves at real time. To relieve this problem, this works presents a solution that introduces speaker cohort models from speaker verification score normalization technique established before, dividing background speakers into small cohorts in advance. As a result, this enables computation burden to be reduced through classifying the enrolling speaker into one of those cohorts and going through enrollment for only that cohort.

• Asian Pacific Journal of Cancer Prevention
• /
• v.16 no.18
• /
• pp.8327-8333
• /
• 2016

Background: The recent epidemiologic transition in Thailand, with decreasing incidence of infectious diseases along with increasing rates of chronic conditions, including cancer, is a serious problem for the country. Breast cancer has the highest incidence rates among females throughout Thailand. Lampang is a province in the upper part of Northern Thailand. A study was needed to identify the current burden, and the future trends of breast cancer in upper Northern Thai women. Materials and Methods: Here we used cancer incidence data from the Lampang Cancer Registry to characterize and analyze the local incidence of breast cancer. Joinpoint analysis, age period cohort model and Nordpred package were used to investigate the incidences of breast cancer in the province from 1993 to 2012 and to project future trends from 2013 to 2030. Results: Age-standardized incidence rates (world) of breast cancer in the upper parts of Northern Thailand increased from 16.7 to 26.3 cases per 100,000 female population which is equivalent to an annual percentage change of 2.0-2.8%, according to the method used. Linear drift effects played a role in shaping the increase of incidence. The three projection method suggested that incidence rates would continue to increase in the future with incidence for women aged 50 and above, increasing at a higher rate than for women below the age of 50. Conclusions: The current early detection measures increase detection rates of early disease. Preparation of a budget for treatment facilities and human resources, both in surgical and medical oncology, is essential.

• Journal of Korean Society of Forest Science
• /
• v.103 no.4
• /
• pp.670-678
• /
• 2014

This paper analyzes the characteristics of population change and makes the population projection in the mountainous area of Korea. Mountainous areas are defined as local towns (eup or myeon) with forest area more than 70 percent of land area, population density less than 111 people per square kilometer, and plowland area less than 21 percent of land area. The population in mountainous areas has decreased dramatically, while the ageing index has increased over the past two decades. To make the population projection, the cohort-change ratios method is applied. The results revealed that a multitude of young people aged 10 to 39 moved to cities to find education and job chance and some people aged 40 and over moved to mountainous areas as the trends of urban-to-rural migration. This continuing trend will culminate in 680 thousand people in population and 1,035 of ageing index in 2030, which will lead to the unequal land development and inefficient forest management. Thus, policy makers need to develop stimulus plans to revitalize and stabilize the economy of mountainous areas.

• Communications for Statistical Applications and Methods
• /
• v.25 no.5
• /
• pp.545-557
• /
• 2018

The inclusion of covariates in the model often affects not only the estimates of meaningful variables of interest but also its statistical significance. Such gap between statistical and subject-matter significance is a critical issue in huge sample studies. A popular huge sample study, the sample cohort data from Korean National Health Insurance Service, showed such gap of significance in the inference for the effect of obesity on cause of mortality, requiring careful consideration. In this regard, this paper proposes a sample size calibration method based on a Monte Carlo t (or z)-test approach without Monte Carlo simulation, and also proposes a test procedure for subject-matter significance using this calibration method in order to complement the deflated p-value in the huge sample size. Our calibration method shows no subject-matter significance of the obesity paradox regardless of race, sex, and age groups, unlike traditional statistical suggestions based on p-values.

• Korean journal of applied entomology
• /
• v.61 no.4
• /
• pp.549-554
• /
• 2022

Life table-related studies in insect ecology have been an interesting topic for insect researchers. Two calculation methods are commonly applied to estimate the intrinsic rate of natural increase (r_m) in the life table statistics. The first method is to estimate an approximate r_m by dividing the natural logarithm of the net reproductive rate (R₀) by mean generation time (T) (namely mean generation time-based method). Another approach is to apply the Lotka-Euler equation derived from the population growth equation of Lotka-Volterra to estimate accurate r_m using the maximum likelihood method (Lotka-Euler equation-based method). In the latter case, there is a difference in the estimated r_m value when the initial age class of the target cohort was set to "0" or "1", which confused the application. In this short review, a brief history of the calculation process of the life table was reviewed. It was again confirmed in the Lotka-Euler equation-based method that the form of $\sum\limits_{x=1}^{w}e^{-rx}l_xm_x=1$ should be applied to estimate r_m when the first age class was set to zero, while the form of $\sum\limits_{x=0}^{w}e^{-r(x+1)}l_xm_x=1$ when set to one.

• Communications for Statistical Applications and Methods
• /
• v.22 no.6
• /
• pp.599-604
• /
• 2015

Kendall's tau statistic has been applied to test an association of bivariate random variables. However, incomplete bivariate data with a truncation and a censoring results in incomparable or unorderable pairs. With such a partial information, Tsai (1990) suggested a conditional tau statistic and a test procedure for a quasi independence that was extended to more diverse cases such as double truncation and a semi-competing risk data. In this paper, we also employed a conditional tau statistic to estimate an association of bivariate interval censored data. The suggested method shows a better result in simulation studies than Betensky and Finkelstein's multiple imputation method except a case in cases with strong associations. The association of incubation time and infection time from an AIDS cohort study is estimated as a real data example.

• 대한예방의학회:학술대회논문집
• /
• 2001.10a
• /
• pp.240-241
• /
• 2001

• Korean Journal of Human Ecology
• /
• v.21 no.4
• /
• pp.629-647
• /
• 2012

This study explored what Korean college students, especially preservice teacher in early childhood education, experienced and how they constructed the meanings of experiences about their subject- matter course (early childhood mathematics education) taught in English. One cohort- 20 senior students- majoring in early childhood education in a 4-year university was participated in this study. Using action research method and narrative research method, data were analyzed. The findings were as follows: 1) preservice teacher experienced some difficulties to construrct professional knowledge through English. 2) They challenged to overcome these difficulties through active participation. 3) They got supports from instructor and peer group. 4) They accomplished the course with self-satisfaction. 5) They experienced the conflicts between social requirements and personal needs.