• The Korean Journal of Physiology and Pharmacology
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• v.26 no.1
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• pp.47-57
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• 2022

Stiripentol is an anti-epileptic drug for the treating of refractory status epilepticus. It has been reported that stiripentol can attenuate seizure severity and reduce seizure-induced neuronal damage in animal models of epilepsy. The objective of the present study was to investigate effects of post-treatment with stiripentol on cognitive deficit and neuronal damage in the cornu ammonis 1 (CA1) region of the hippocampus proper following transient ischemia in the forebrain of gerbils. To evaluate ischemia-induced cognitive impairments, passive avoidance test and 8-arm radial maze test were performed. It was found that post-treatment with stiripentol at 20 mg/kg, but not 10 or 15 mg/kg, reduced ischemia-induced memory impairment. Transient ischemia-induced neuronal death in the CA1 region was also significantly attenuated only by 20 mg/kg stiripentol treatment after transient ischemia. In addition, 20 mg/kg stiripentol treatment significantly decreased ischemia-induced astrocyte damage and immunoglobulin G leakage. In brief, stiripentol treatment after transient ischemia ameliorated transient ischemia-induced cognitive impairment in gerbils, showing that pyramidal neurons were protected and astrocyte damage and blood brain barrier leakage were significantly attenuated in the hippocampus. Results of this study suggest stiripentol can be developed as a candidate of therapeutic drug for ischemic stroke.

• Journal of Korean Academy of Nursing
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• v.52 no.2
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• pp.121-133
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• 2022

Purpose: This study examined the impact of a virtual reality intervention program based on psychological needs on behavioral and psychological symptoms, apathy, and quality of life (QOL) in patients with dementia or mild cognitive impairment living in nursing facilities. Methods: This study is nonequivalent control group pretest-posttest design of quasi-experimental study. The study collected data from November 18, 2020 to July 24, 2021 from patients with dementia or mild cognitive impairment (30 in the experimental group and 30 in the control group) at three nursing facilities in G city using self-reporting and caregiver-informant reporting methods. The analysis employed the chi-square test, Fisher's exact test, paired t-test, independent t-test, Wilcoxon signed rank test, Mann-Whitney U, repeated measures ANOVA, GEE, using SPSS/WIN 27.0. Results: The severity of behavioral and psychological symptoms (Wald 𝛘² = 2.68, p = .102) and the care burden of caregivers (Wald 𝛘² = 1.72, p = .190) were not significant and was no significant time and group interaction effect (Wald 𝛘² = 0.63, p = .426, Wald 𝛘² = 0.52, p =. 471). The difference in apathy and QOL score were statistically significant for the group-time interaction (F = 43.65, p < .001; F = 4.35, p = .041). Conclusion: The virtual reality intervention program of this study shows a positive effect on the apathy reduction and QOL of patients with dementia or mild cognitive impairment residing in nursing facilities.

• Women's Health Nursing
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• v.28 no.4
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• pp.275-285
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• 2022

Purpose: This study explored the experiences of pregnant women with depressed mood participating in a group cognitive behavioral therapy (CBT) program using video communication, based on Beck's cognitive theory. Methods: The participants were six pregnant women out of 13 women who had participated in an 8-session group CBT program using video communication for women with depressed mood (Edinburgh Postnatal Depression score of ≥9). Data were collected from February 20 through March 25, 2021. In-depth individual interviews were conducted through a video conferencing platform at 1 month post-baseline. Thematic analysis was done. Results: Three themes, 10 subthemes, and 38 concepts were derived from experiences of participating in the 4-week group CBT program (twice a week). The first theme, entitled "continuing realization" had subthemes of "a negative and instable self," "a selfish judgment that excludes others," and "a strong belief in self-control." The second theme, entitled "attempt to change for restoration" had subthemes of "shift to rational thinking," "freedom from suppressed beliefs," "tolerance of other people," and "courage for self-expression." The third theme, entitled "departure for a positive life," had subthemes of "emotional healing," "faith in oneself," and "reestablishing the criteria for happiness." Conclusion: Pregnant women with depressed mood expressed that continuing realizations and attempts to change supported their transition toward a positive direction of healing. Thus, they were able to change their distorted thinking into rational thinking through CBT using video communication. These findings support the use of group CBT using video communication with pregnant women who have depressed mood.

• Journal of the Korean Chemical Society
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• v.54 no.1
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• pp.150-157
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• 2010

In this study, we investigated the differences of mapping understanding and the types of mapping errors by the levels of students' cognitive/affective variables and the relationships between mapping understanding and these variables in learning 'concentration and reaction rate' with analogy. After administering the tests regarding logical thinking ability, visual imagery ability, analogical reasoning ability, self efficacy, and need for cognition as pretests, students learned with analogy. Then, students' familiarity and mapping understanding were examined. Analyses of the results revealed that the scores of the mapping understanding for the students with higher levels of all cognitive/affective variables except visual imagery ability and familiarity were significantly higher than those for the students with lower levels. The differences in the types of the mapping errors such as overmapping, failure to map, impossible mapping, artificial mapping, mismapping, rash mapping, and retention of a base feature were also found by the levels of students' cognitive and affective variables. The scores of students' mapping understanding were positively correlated with those of all cognitive and affective variables. The results of multiple regression analysis indicated that students' science achievement, logical thinking ability, and familiarity were significant predictors of mapping understanding. Educational implications of these findings are discussed.

• Asia-Pacific Journal of Business Venturing and Entrepreneurship
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• v.9 no.4
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• pp.145-153
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• 2014

This study examined the linkage between positive cognitive bias and entrepreneurial intention. Self-enhancement, unrealistic optimism, and illusion of control have been collectively referred as positive cognitive bias. We examined the effects of positive cognitive bias on attitudes toward success and failure. And we also examined the effect of attitudes toward success and failure on entrepreneurial intension. This study investigated these relationships using 240 high school students. The result of analysis indicated that the self-enhancement bias and unrealistic optimism bias had positive effects on attitude toward failure, but it had not any effect on attitude toward success. The illusion of control bias has positive effects on attitude toward success, but it had not any effect on attitude toward failure. The attitudes toward success and failure had positive effect on entrepreneurial intension. Then results of this study suggests that the cognitive biases showed a role of antecedents of attitudes toward success and failure. Finally, this study concluded with a discussion of the implications of the research findings and directions for future research.

• Science of Emotion and Sensibility
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• v.16 no.2
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• pp.249-264
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• 2013

Using social network analysis, this study examined cognitive representations of ideal public figures as well as politicians and entertainers who are often regarded as public figures in Korea. Participants expected ideal public figures to possess only positive characteristics, such as high morality, integrity, competence. However, their assessment of politicians and entertainers reflected in their cognitive representations turned out to be fairly different from the image of ideal public figures. Personality traits and behavioral characteristics featured in cognitive representations of politicians were dominantly negative. Cognitive representations of entertainers incorporated both positive and negative characteristics highly interconnected to each other. This study also explored how people respond affectively toward ideal public figures, politicians and entertainers. Participants showed only positive feelings toward ideal public figures. However, their' affective responses toward politicians were entirely negative and toward entertainers, both positive and negative affects were shown. We discussed the disjunction between the representations of politicians and entertainers and of ideal public figures and suggested directions of future research.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.21 no.7
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• pp.544-554
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• 2020

The purpose of this research was to determine the effect of baking and pastry activity programs on the cognitive function of the elderly with dementia. The study was carried out on 19 elderly with dementia who attended K city C daycare center and who provided consent. A total of 10 elderly were assigned to the experimental group, and the other nine were assigned to the control group. To test the effectiveness of the program, this research used the pretest-posttest control group design. The experimental group administered the program from January 2, 2017 to February 28, 2017. However, the control group did not undergo a separate program. Fisher's accuracy test was performed to identify the homogeneity of the experimental and control groups. Mann-Whitney U Test was conducted to identify the homogeneity of the cognitive functions of the experimental and control groups prior to the launch of the program. Wilcoxon Matched-Pairs Signed-Rank and Mann-Whitney U Test were conducted to determine the effects of the program on the cognitive function of the elderly with dementia. As a result, the program verified the effect on the cognitive function of the elderly with dementia. According to these findings, the important issues and limitations of the research are discussed.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.18 no.5
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• pp.355-365
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• 2017

This study investigatedwhether occupational therapeutic craft activity improves cognitive function and hand function in patients with acute stroke, with the hope of providing clinically useful results for further studies. From March 2016 to November 2016, thirty acute patients with stroke at A general hospital and B rehabilitation hospital in Seoul and Gyeonggi-do, Korea were enrolled and randomly divided into two groups. One group was treated with occupational therapeutic craft activity,and the other general exercise. The subjects performed each activity for 30 minutestwice weekly, for four weeks. To test the effect of intervention, hand function was tested with the Box & Block Test and the Jebsen-Taylor Hand Function Test.Cognitive function measures were the NCSE and Trail-Making Test. Over the four weeks of treatment activities, in the occupational therapeutic craft activity group, hand function measures(p<.05) increased significantly,as did cognitive function measures(p<.05). This study shows that occupational therapeutic craft activity improves hand function and cognitive function effectively in patients with acute stroke. Occupational therapeutic craft activity programscan be based on this study to prepare intervention programs for further studies with acute stroke patients.

• Science of Emotion and Sensibility
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• v.6 no.3
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• pp.63-72
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• 2003

This study investigated how cognitive style and training context influenced visual discrimination skill acquisition and transfer under time pressure. This experiment consisted of a screening session, a training session, and a transfer session using random polygon comparison tasks. Screening session was designed to separate participants according to their cognitive style (analytic or holistic). Training session was divided into difficult and easy conditions. In transfer session, participants compared polygon pairs in a novel task. The stimuli were presented for 1.5 seconds to examine the influence of time pressure. Through the all sessions, this experiment measured accuracy and response time. According to the results of this study, analytic group responded as quickly as holistic group in the beginning of training session because time pressure induced them to the holistic strategy. However, as training session progressed, their slopes of reaction time increased, suggesting that their own analytic style emerged. Holistic group showed flatter slopes than did analytic group for training session. Of interest is the slopes increased at the beginning of transfer session, suggesting that they developed analytic strategies in difficult training context. It is suggested individuals differently develop strategic processing skills depending on cognitive styles even under time pressure.

• Therapeutic Science for Rehabilitation
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• v.1 no.1
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• pp.29-38
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• 2012

Introduction : This study reviews the main areas of cognitive rehabilitation including executive dysfunction, memory dysfunction, perceptual dysfunction, attention deficit, and dysfunctions in activities of daily living in order to apply to the adaptation of occupational therapy. Body : Cognition programs based on the virtual reality are being used not only to evaluate but to train the overall components of human's cognition. Because the cognitive program is concentrating on the real environment, it is known to bring a remarkable transitional effect to the actual environment, compared to the basic computer-based evaluation and training. Applying virtual reality to the rehabilitation program can develop and advance the high technology and can result in a major effect on the innovative treatment technology. Conclusions : In this process, virtual reality is expected to be researched more in the near future. Particularly in the cognitive realm, it is imperative for researchers to pay attention to the improved transitional effect of the virtual reality toward the actual environment, rather than the already existing method of evaluations. Therefore, application of the virtual reality for the cognitive training should be researched for various types of subjects in the diverse aspects of congnitive function. Application of the virtual reality in the cognitive function has its unlimited potential, thus the rehabilitation program integrated with not only evaluation but training and education is expected extensively in the future.