• 대한간호학회지
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• 제29권6호
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• pp.1355-1364
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• 1999

Mother and infant relationship has a great influence on child's developments. In this study, nursing intervention to increase maternal sensitivity to the infant's cues was applied to 25 primiparas (Experimental Group). Mother and infant interacations of these primiparas were compared with those of 25 primiparas (Control Group) who did not receive the nursing intervention. Fifty primiparas and infants were recruited from a university hospital, a general hospital, and an OBGY clinic located in Taegu city. Mother and infant interactions were assessed at 6 weeks after birth using videotapes. Feeding situations were videotaped and two trained observers analyzed the tapes. Data were collected from March 23rd to July 27th of 1998. Mother and infant interactions during feeding were assessed by the response rating scale which was modified by the author based on NCAST feeding scale (Barnard, 1978a) and AMIS scale (Price, 1983). The validity of the modified rating scale was verified by faculty members and researchers who previously had research experience in the area. Cronbach's Alpha of the modified scale for this study was .90. The data was analyzed by SAS program, using wilcoxon rank sums test, chi square test, Fisher's exact test, and ANOVA. Findings were as follows: 1. Mothers in the experimental group were more likely to have higher scores in mother and infant interactions during feeding than mothers in the control group. 2. Mothers in the experimental group showed better sensitivity to infant's signals or cues, provided growth fostering, and had higher responsibility to the infant's distress than mothers in the control group. 3. Infants in the experimental group showed higher clarity of cues and responsibility to the mother's behaviors than infants in the control group. 4. Mothers and infants in the experimental group showed higher synchronic responses than mothers and infants in the control group. In conclusion, this study has shown that the applied nursing intervention promoted mother and infant interaction among primiparas. Therefore, this study suggests that the nursing interventions to increase maternal sensitivity to the infant's cues should be broadly applied to primiparas, which can be beneficial to the social, affective, and cognitive developments of their children.

• 대한간호학회지
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• 제29권6호
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• pp.1392-1402
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• 1999

This study was carried out to find out stress-eating relationship in obese high school girls and to investigate the factors related to stress-induced eating. The conceptual framework used in this study was individual difference model. The research method was methodological triangulation. The data of the study were collected from purposively sampled 309 normal high school girls and 314 obese high school girls in S city. 15 volunteers, obese high school girls, enrolled in this qualitative research. Quantitative data was collected from May 6 to June 10, 1997 through questionnaires about stress and stress-related eating changes and from June 23 to August 26, 1997, qualitative data was collected. The results of the study were as follows : 1. Obese high school girls were unaffected by stress(t=-1.84, p=0.0662). 2. Through quantitative analysis, obese people divided into two groups in their response to stress. One group was composed of stress- eater. The other group was composed of non- stress eater. 3. Disinhibition(t=-3.1275, p=0.0019), cognitive restrain (t=-3.1597, p=0.0017), hunger(t=-3.5878, p=0.0004) were significantly different between stress-eaters and non-stress eaters. 4. According to the interview, 5 subjects of obese girls were stress eaters, and 10 subjects were non-stress eaters. Through qualitative research, the related factors of eating were eating attitude & behavior, stimuli situations on eating, and personality. In stress-eater group, they constantly went on a diet, however, they were prompted to eat when an uneasy feeling such as anxiety, depression, annoyance developed. Their personality were entirely optimistic. Whereas non-stress eater group had no interest in diet and didn't appear to have psychological factors to stimulate eating in stressful situations. Their personality was not only optimistic but also keenly characteristic. 5. To compare obese-normal high school girls on the effect of stress in eating. Normal weigh high school girls decreased their eating when stressed(t= -13.62, p=0.0001). In conclusion, this study suggests that there are two different groups in obese high school girls in regards to eating responses on stressful situations. As a result of these finding, clinical and school nurses can detect the stress-eaters who need stress management intervention, and can apply appropriate management program according to the individual needs.

• 한국학교보건학회지
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• 제28권2호
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• pp.56-66
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• 2015

The purpose of this study was to investigate factors associated with coping responses in Korean public high school students. Methods: This study employed a descriptive survey research design. The sample included 263 high school students who responded to a self-report questionnaire. Variables included socio-demographic characteristics, health-related characteristics, academic stress, somatization symptoms, social support, and coping responses. Data were analyzed using descriptive statistics, t-tests, ANOVA, Pearson's correlations, and multiple regressions. Results: Participants, regarding their school life, reported moderate levels of academic stress ($M{\pm}SD=2.3{\pm}0.52$) and somatization symptoms ($M{\pm}SD=2.3{\pm}0.71$), and a relatively high level of social support ($M{\pm}SD=4.2{\pm}0.67$). All the variables were associated with the use of multiple coping responses. Active-cognitive coping ($M{\pm}SD=2.9{\pm}0.68$) was most frequently used, followed by active-behavioral coping ($M{\pm}SD=2.5{\pm}0.56$). and avoidant coping ($M{\pm}SD=2.3{\pm}0.75$). Significant relationships were found among the measured variables: positive relation between academic stress and somatization symptoms, but, negative between academic stress and both somatization symptoms and social support. Students who had higher stress and more somatization symptoms were more likely to use avoidant coping than the others. In multiple regression analysis, while factors associated with each coping response differed, gender appeared to be a significant factor in all methods. Variables included in the final model explained 27% of the variance in avoidant coping (F=11.40, p<.001). Conclusion: Based on the study results, schools should provide tailored educational programs to help high school students reduce multisource stress and somatization symptoms at school and cope with them in more active and effective ways.

• 영재교육연구
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• 제22권3호
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• pp.729-755
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• 2012

우리나라의 소외된 영재를 이해하기 위한 노력의 일환으로 질적 사례연구 기법을 적용하여 가난하고 신체적 아픔이 있는 과학영재의 학습 특성과 전술에 대해 알아보았다. 이를 위해 연구 현장인 주말 물리교실을 중심으로 참여관찰을 했고, 참여자와 참여자의 어머니, 초등학교 5학년 때 담임교사와 면담을 진행하였다. 또한 현지문헌과 자기보고서를 추가로 활용하여 참여자를 종합적으로 이해하고자 했다. 그 결과, 참여자의 학습 특성은 내적동기와 열등감에서 기인하는 '능동적인 학습'과 배척된 관계 속에서 드러나는 '배움을 향한 몸부림'으로 정리할 수 있었다. 참여자의 학습 전술은 경제적 여력이 충분하지 않은 상태에서 배움에 대한 욕구를 충족하기 위한 전략적인 수단으로 '다양한 학습 경로'과 '메타인지적 사고', 그리고 '맞장구치기'의 세 전술을 발견하였다.

• 한국콘텐츠학회논문지
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• 제15권3호
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• pp.57-67
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• 2015

이 연구의 목적은 초등 과학 영재 학생들을 대상으로 과학박물관 탐방학습을 실시하여 관찰의 유형을 분류하고 이를 분석하였다. 이를 위해 과학 영재 학생 10명을 선정하여 탐방학습이 진행되는 동안 일어나는 관찰을 언어로 표현하도록 하여 모든 관찰 내용과 대화를 녹음하였다. 그 결과는 다음과 같다. 인지적 측면에서는 응답의 빈도가 높았고 자신의 의견을 배제하고 전시물과 관련하여 질문하고 응답하는 빈도가 높았으며, 정의적 측면에서는 권유의 빈도수가 가장 많았다. 관찰의 유형을 분류하고 이를 분석한 결과에서는 단수의 관찰 대상 전체를 시간 독립적으로 관찰하는 빈도가 높고, 시각을 사용하여 조작을 하지 않고 정성적인 방법으로 관찰하는 빈도가 높았다. 따라서 질문을 통한 언어적 상호작용은 관찰의 빈도와 다양성에 긍정적인 영향을 주며, 과학박물관 탐방학습에서 과학 영재 학생들의 다양한 관찰을 유도하기 위해서는 프로젝트 학습과 같은 특정 전시관이나 전시물을 학생이 직접 선택하여 집중 탐구할 수 있는 시간이나 학습지를 마련하면 더 효과적인 관찰 학습이 이루어질 수 있을 것으로 보인다.

• 디지털산업정보학회논문지
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• 제11권4호
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• pp.113-127
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• 2015

An interface in smart device environment is changing to TUI(touch user interface) environment where a system is being controlled by physical touch, differently from a system controlled through conventional mouse and keyboard. What is more important than anything else in this TUI environment is to implement interface in consideration of learn ability and cognitive constructivism according to user's experience. Therefore, now is the time when it is necessary to carry out various studies on smart content design process going a step farther together with discussing the details of user's experience factor. Hence, this study was intended to look into what effect a user's experiential traits had on the production of contents for the purpose of measures for improving TUI user satisfaction in order to effectively realize contents in smart environment. Results were yielded by using a statistical empirical analysis such as cross-tabulation analysis according to important variable and user, paired t-test, multiple response analysis, and preference frequency analysis of user preference on the basis of a survey. As a result, a system was presented for implementing DFSS(Design For Six Sigma) process. TUI experience factor can be divided into direct habitual experience, direct learning experience, indirect habitual experience, and indirect learning experience. And in the results of study, it was possible to find that the important variables of this study had a positive effect on the improvement of use satisfaction with contents on the whole according to the user convenience of smart contents. This study is expected to have a positive effect on efficient smart device-based contents production by providing objective information according to empirical analysis to smart media-based developer and designer and presenting a model for improving the changed TUI usability.

• 한국약용작물학회지
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• 제28권2호
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• pp.85-94
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• 2020

Background: Alzheimer's disease (AD) is caused by various factors, such as cholinergic dysfunction, regulation of neurotrophic factor expression, and accumulation of amyloid-beta. We investigated whether or not a combination of Carthamus tinctorius L. seed and Taraxacum coreanum (CT) has a protective effect on scopolamine-induced memory impairment in a mouse model. Methods and Results: Mice were orally pretreated with CT (50, 100 and 200 mg/kg/day) for 14 days, and scopolamine (1 mg/kg/day) was injected intraperitoneally before subjecting them to behavior tests. CT-administered mice showed better novel object recognition and working memory ability than scopolamine-treated control mice. In T-maze and Morris water maze tests, CT (100 and 200 mg/kg/day) significantly increased space perceptive ability and occupancy to the target quadrant, respectively. In addition, 100 and 200 mg/kg/day of CT attenuated cholinergic dysfunction through inhibition of butyryl cholinesterase in brain tissue. Furthermore, CT-administered mice showed higher cyclic adenosine monophosphate-response element-binding protein (CREB) levels and lower amyloid precursor protein (APP) levels compared to scopolamine-treated control mice. Conclusions: CT improved scopolamine-induced memory impairment through inhibition of cholinergic dysfunction, up-regulation of CREB, and down-regulation of APP. Therefore, CT could be a useful therapeutic agent for AD with protective effects on cognitive impairment.

• Clinical and Experimental Pediatrics
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• 제63권1호
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• pp.25-29
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• 2020

Background: Pain during the developmental period may adversely affect developing neuronal pathways and result in adverse neurodevelopmental, cognitive, and behavioral effects in later life. Immunizations, e.g., hepatitis B vaccine (HBV), administered at birth are painful experiences to which neonates are universally subjected. Purpose: Here we aimed to study and compare the effectiveness of various nonpharmacological pain management methods in newborns to enable the development of safe and effective analgesic methods for newborns. Methods: This prospective study was conducted at a tertiary care hospital in the Himalayan region. Three hundred term healthy neonates were divided into 6 groups of 50 each. Groups 1-5 were intervention groups, patients of which received a nonpharmacological intervention (breastfeeding, nonnutritive sucking, rocking, 25% sucrose, or distilled water) before the intramuscular HBV, while patients in group 6 received no intervention. The pain response in each group after the HBV injection was assessed and compared using cry duration and Douleur Aigue Nveau-ne (DAN) score, a behavioral acute pain rating scale for newborns. Results: Cry duration was decreased in all intervention groups, significantly so in the sucrose (19.90 seconds), breastfeeding (31.57 seconds), and nonnutritive sucking (36.93 seconds) groups compared with controls (52.86 seconds). DAN scores decreased significantly (P<0.05) at one or more points i.e. 30, 60, or 120 seconds in the breastfeeding and 25% sucrose intervention groups compared with controls. Conclusion: Oral sucrose and nonnutritive sucking are simple yet underutilized nonpharmacological interventions that effectively reduce pain in newborns.

• The Korean Journal of Physiology and Pharmacology
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• 제21권6호
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• pp.579-589
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• 2017

Anesthetics are used extensively in surgeries and related procedures to prevent pain. However, there is some concern regarding neuronal degeneration and cognitive deficits arising from regular anesthetic exposure. Recent studies have indicated that brain-derived neurotrophic factor (BDNF) and cyclic AMP response element-binding protein (CREB) are involved in learning and memory processes. Genistein, a plant-derived isoflavone, has been shown to exhibit neuroprotective effects. The present study was performed to examine the protective effect of genistein against isoflurane-induced neurotoxicity in rats. Neonatal rats were exposed to isoflurane (0.75%, 6 hours) on postnatal day 7 (P7). Separate groups of rat pups were orally administered genistein at doses of 20, 40, or 80 mg/kg body weight from P3 to P15 and then exposed to isoflurane anesthesia on P7. Neuronal apoptosis was detected by TUNEL assay and FluoroJade B staining following isoflurane exposure. Genistein significantly reduced apoptosis in the hippocampus, reduced the expression of proapoptotic factors (Bad, Bax, and cleaved caspase-3), and increased the expression of Bcl-2 and Bcl-xL. RT-PCR analysis revealed enhanced BDNF and TrkB mRNA levels. Genistein effectively upregulated cAMP levels and phosphorylation of CREB and TrkB, leading to activation of cAMP/CREB-BDNF-TrkB signaling. PI3K/Akt signaling was also significantly activated. Genistein administration improved general behavior and enhanced learning and memory in the rats. These observations suggest that genistein exerts neuroprotective effects by suppressing isoflurane-induced neuronal apoptosis and by activating cAMP/CREB-BDNF-TrkB-PI3/Akt signaling.

• 한국융합학회논문지
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• 제8권6호
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• pp.1-7
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• 2017

본 연구는 디지털 사이니지와 스마트 기술이 융합되면서 디지털 사이니지의 상호작용성(고/저)와 인게이지먼트(고/저)에 따라 기억 효과와 브랜드 태도 효과의 차이가 어떻게 나타나는지를 살펴보았다. 2X2 피험자간 요인설계를 통해 실증적으로 분석하였으며, SPSS 18을 이용하여 Two Way MANOVA분석을 통해 검증하였다. 연구 결과, 첫째, 디지털 사이니지의 상호작용성과 인게이지먼트 수준이 낮으면 '종합적 기억정보'가 많이 회상되나 두 조건이 모두 높으면 '속성기억정보'가 회상되는 것으로 나타났다. 둘째, 디지털 사이니지의 상호작용성이 낮고 인게이지먼트 수준이 높으면 제품의 제품에 대한 전반적인 태도를 형성하는 기억 정보가 많이 회상되었다. 또한 상호작용성 수준이 높고 인게이지먼트가 낮아도 속성 정보보다는 전반적인 평가를 통한 태도적인 인지 반응이 높게 형성되었다. 셋째, 브랜드 태도는 상호작용성 수준이 나자고 인게이지먼트 수준이 높을 때 긍정적이었다. 이는 디지털 사이니지를 통해 제품에 대한 태도를 긍정적으로 형성시키기 위해서는 상호작용을 최소화하는 대신 디지털 사이니지 미디어 자체에 대한 몰입을 극대화하는 방안이 브랜드에 대한 경험을 통해 태도 형성에 긍정적인 영향을 미칠 수 있다.