• Journal of the Korea Academia-Industrial cooperation Society
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• v.21 no.9
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• pp.358-372
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• 2020

This study examined the effect of cognitive reserve on the cognitive function in adults. In addition, this study investigated the direct and indirect effects of factors, such as subjective memory decline, depression, and quality of life on the cognitive function. The participants consisted of 253 adults who were 40 to 80 years of age. The assessment tools included the cognitive function scale, depression scale, quality of life scale, subjective memory decline, and cognitive reserve scale. The data results were analyzed using SPSS 25.0, and PROCESS macro for SPSS Version 3.3 and bootstrapping were used. The results of multiple mediating of the cognitive reserve and cognitive function in adults did not have a mediating effect in depression and subjective memory decline, and the quality of life showed a complete mediating effect in the relationship between the cognitive reserve and subjective cognitive function. Based on the results of this study, adults must accumulate cognitive reserve continuously through various activities and continuous training so that the cognitive function can lead to a positive direction. Nevertheless, more studies on cognitive reserve and cognitive function in healthy adults are needed.

• The Journal of the Korea Contents Association
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• v.15 no.11
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• pp.359-373
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• 2015

Cognitive reserve(CR) is the ability to optimize or maximize performance through complementary brain networks. CR is relevant to normal aging in cognitive-linguistic abilities. There are few domestic systematic reviews or meta-analyses that analyze the relationships between multiple CR and cognitive-linguistic domains in healthy older people. This meta-analysis included 32 studies published since 2000. In result, education level topped the list, followed by the occupation, cognitively stimulating activities, and the multilingualism. Most studies were related to memory, global cognition, and language. CR had a modest positive association with cognitive-linguistic performance. Multiple domains including memory and language also showed the significant correlations across most measures of CR. This study provides evidence-based information to support cognitive-linguistic ability in normal aging.

• Journal of Physiology & Pathology in Korean Medicine
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• v.38 no.1
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• pp.1-9
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• 2024

Cognitive reserve (CR) is a concept that can explain the discrepancies between the pathologic burden of the disease and clinical manifestations. It refers to the individual susceptibility to age-related brain changes and pathologies related to Alzheimer's disease, thus recognized as a factor affecting the trajectories of the disease. The purpose of this study was to explore the current states of clinical studies on neural substrates of CR in Alzheimer's disease using functional magnetic resonance imaging. We searched for clinical studies on CR using fMRI in the Pubmed, Cochrane library, RISS, KISS and ScienceON on August 14, 2023. Once the online search was finished, studies were selected manually by the inclusion criteria. Finally, we analyzed the characteristics of selected articles and reviewed the neural substrates of CR. Total thirty-four studies were included in this study. As surrogate markers of CR, not only education and occupational complexity, but also composite score and questionnaire-based method, which cover various areas of life, were mainly used. The most utilized methods in resting-state fMRI were independent component analysis, seed-based analysis, and graph theory analysis. Through the analysis, we demonstrated that neuroimaging techniques could capture the neural substrates associated with cognitive reserve. Moreover, functional connectivity of brain regions centered on prefrontal and parietal cortex and network areas such as default mode network showed a significant correlation with CR, which indicated a significant association with cognitive performance. CR may induce differential effects according to the disease status. We hope that this perspective on cognitive reserve would be helpful when conducting clinical researches on the mechanisms of traditional Korean medicine for Alzheimer's disease in the future.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.16 no.5
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• pp.3188-3198
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• 2015

This study explores the health behaviors and related situations of Korean low-income breast cancer survivors using in-depth interview. The study derives 95 concepts, 23 sub-categories and 12 categories in open coding. Illness experiences were categorized by behavioral, psychological, and social domains, cognitive were categorized by causal and destiny thought, emotions were categorized by negative, positive emotion, reserve capacity were categorized by internal and external domains and health behaviors were categorized by behavioral, psychological, and social domains. Understanding illness experience, cognitive, emotion, reserve capacity and health behaviors for Korean low-income breast cancer survivors will be useful in developing social welfare interventions and for enhancing health promotion.

• Journal of Preventive Medicine and Public Health
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• v.52 no.5
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• pp.333-343
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• 2019

Objectives: This study aimed to evaluate the association between dental implants and cognitive function in community-dwelling older adults. Methods: Data were collected from the baseline survey (2016-2017) of the Korean Frailty and Aging Cohort Study. The study sample comprised 1115 community-dwelling people aged 70 years to 84 years who had 0-19 natural teeth. Dental implants and natural teeth were identified by panoramic radiography, while the cognitive function was assessed by the Korean version of the Mini-Mental State Examination (MMSE-KC). The association between dental implants and cognitive function was analyzed by multiple linear regression. Sensitivity analysis was performed to test for potential bias. Results: The mean number of natural teeth in the study population was 9.50 (standard deviation [SD], 6.42), and the mean MMSE-KC score was 24.93 (SD, 3.55). In the simple univariate analysis, tooth replacement, age, sex, smoking status, alcohol consumption, body mass index, osteoporosis, number of natural teeth, periodontitis, chewing discomfort, tooth-brushing frequency, education level, monthly household income, participation in economic activity, living alone, and marital status had a significant impact on the association. After adjusting for confounders, the association between dental implants and cognitive function remained significant (B, 0.85; standard error, 0.40; p<0.05). Age, body mass index, periodontitis, tooth-brushing frequency, and education level were also significantly associated with cognitive function. The results of the sensitivity analyses were consistent with those of the primary analysis. Conclusions: Dental implants were associated with cognitive function in older adults living in the community. Dental implants as tooth replacements may play a role in preserving cognitive function.

• The Journal of the Korea Contents Association
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• v.20 no.10
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• pp.458-469
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• 2020

Geriatric depression is associated with pathological changes in the brain and increases the risk of cognitive impairment or dementia. However, high cognitive reserve, such as high education, can delay or minimize clinical manifestations of pathologies involving the brain, so the effect of geriatric depression on cognitive impairment or dementia may vary depending on the education level. In this study, the author analyzed data from the Korean Longitudinal Study of Aging (KLoSA) to examine whether the effect of geriatric depression on cognitive function differed depending on education level. Among the 10,254 subjects registered in the KLoSA, the 4,905 subjects who met the inclusion criteria were analyzed by stepwise regression analysis. The results were as follows: first, depressive symptoms predicted low cognitive function after 12 years; second, the negative effect of depressive symptoms on cognitive function after 12 years was higher in the old adult group than in the young adult group; and third, the effect of age was significant only in the low-educated group. These results suggest that depressive symptoms in low-educated old adults may increase the risk of development of dementia in the long term.

• Journal of Advanced Navigation Technology
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• v.17 no.4
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• pp.435-441
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• 2013

This paper proposes a neural net based-predictive connection admission control (CAC) scheme for multiclass users in wireless cognitive radio networks. We classifies cognitive users(cu) into real and non real time services, and then permit only real time services to reserve the demanded resource for spectrum handoff in guard channel for provisioning the desired QoS. Neural net is employed to predict primary user's arrival on time and demanded channels. Resource scheduling scheme is based on $C_IA$(cognitive user I complete access) shown in this paper. For keeping primary users from interference, the CAC is performed on only cognitive user not primary user. Simulation results show that our schemes can guarantee the desired QoS by cognitive real time services.

• Journal of Digital Convergence
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• v.18 no.11
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• pp.87-97
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• 2020

This study summarized longevity factors of enterprises and presented longevity mechanism. By analogy of human aging and corporate longevity, the company's decline and longevity phenomenon were analyzed to derive corporate longevity mechanism, presented domestic and foreign longevity enterprises' cases study using above mechanism. The longevity mechanism first, as the human body restricts free radicals by dietary restrictions, companies also need continuous input efficiency. Second, as cognitive reserve by high thinking activities helps heath lifespan, companies can strengthen their profitability by continuous R&D. Third, as humans improve antioxidant functions by exercise, companies should develop risk management capabilities for environmental changes. This study can contribute to sustainable strategies for corporate managers, ultimately plan to suggest model of evaluation or diagnosis of corporate longevity.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.21 no.5
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• pp.150-166
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• 2020

Based on the theory of cognitive reserve, we undertook this study to develop a cognitive function training program for woman in menopausal transition with complaints of declining in cognitive function. The program was established by applying the analysis, design, and development stages of the network-based instructional system designed by Jung. The cognitive function training program developed by us is an was an 8-week program composed of cognitive and video training using a mobile application. The program consists of 24 sessions, each with 20-30 minutes of duration, to be completed 3 sessions per week. The contents of the cognitive function training comprise of memory, attention, language function, and scenario-based problem-solving for executive functions, all of which are cognitive areas found to be the most vulnerable for menopausal women. The educational contents were developed for eight subject areas, one subject area per week, including the definition of menopause, its causes and symptoms, menopause and brain function, etc. During the pilot test, the cognitive function training program was applied to 10 menopausal women who complained of cognitive function decline. The results indicated that, after eight weeks of training, the overall cognitive function of participants increased, revealing statistically significant differences (t=-3.04, p=.014) after the program was completed. The mobile app-based cognitive function training program might not only improve patients' memory functions but also potentially reduce the incidence of dementia.

• Journal of Korean Neurosurgical Society
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• v.56 no.3
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• pp.188-193
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• 2014

Objective : Moyamoya disease (MMD) is a chronic cerebrovascular occlusive disease of unknown etiology. In addition, the neurocognitive impairment of adults with MMD is infrequently reported and, to date, has not been well described. We attempted to determine both the neurocognitive profile of adult moyamoya disease and whether a superficial temporal artery-middle cerebral artery (STA-MCA) anastomosis can improve the neurocognitive impairment in exhibiting hemodynamic disturbance without stroke. Methods : From September 2010 through November 2012, 12 patients with angiographically diagnosed MMD underwent STA-MCA anastomosis for hemodynamic impairment. Patients with hypoperfusion and impaired cerebrovascular reserve (CVR) capacity but without evidence of ischemic stroke underwent a cognitive function test, the Seoul Neuropsychological Screening Battery (SNSB). Five patients agreed to undergo a follow-up SNSB test. Data from preoperative and postoperative neurocognitive function tests were compared and analyzed. Results : Five of 12 patients were enrolled. The median age was 45 years (range, 24-55 years). A comparison of preoperative to postoperative status of SNSB, memory domain, especially delayed recall showed significant improvement. Although most of the domains showed improvement after surgery, the results were not statistically significant. Conclusion : In our preliminary study, large proportions of adult patients with MMD demonstrate disruption of cognitive function. This suggests the possibility of chronic hypoperfusion as a primary cause of the neurocognitive impairment. When preoperative and postoperative status of cognitive function was compared, memory domain showed remarkable improvement. Although further study is needed, neurocognitive impairment may be an indication for earlier intervention with reperfusion procedures that can improve cognitive function.