• Title/Summary/Keyword: Coagulation test

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Blood Compatibility of Hollow Fiber Membranes Treated by Plasma Polymerization (플라즈마 중합 처리된 중공사 막의 혈액 적합성)

  • Lee, Sam-Cheol;Kwon, O-Sung
    • Membrane Journal
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    • v.15 no.3
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    • pp.233-240
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    • 2005
  • Surface modification of polypropylene hollow fiber membranes was performed in order to develop blood-compatibility biomaterials for use in the blood contacting surfaces and oxygenation membranes of a lung assist device (LAD), important medical device even more useful. Blood compatibility of materials was determined by using anticoagulation blood and evaluating formation of blood clots on their surfaces as well as activation of plasma coagulation cascade, platelet adhesion, and aggregation. It was verified that the number of platelets on the silicone coated fibers was significantly lower than that on untreated fiber membrane, indicating improved blood compatibility. It was also found that the polypropylene hollow fiber membranes using plasma treatment exhibited suppression of complement activation in blood compatibility test.

Seasonal variation of assimilable organic carbon and its impact to the biostability of drinking water

  • Choi, Yonkyu;Park, Hyeon;Lee, Manho;Lee, Gun-Soo;Choi, Young-june
    • Environmental Engineering Research
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    • v.24 no.3
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    • pp.501-512
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    • 2019
  • The seasonal effects on the biostability of drinking water were investigated by comparing the seasonal variation of assimilable organic carbon (AOC) in full-scale water treatment process and adsorption of AOC by three filling materials in lab-scale column test. In full-scale, pre-chlorination and ozonation significantly increase $AOC_{P17\;(Pseudomonas\;fluorescens\;P17)}$ and $AOC_{NOX\;(Aquaspirillum\;sp.\;NOX)}$, respectively. AOC formation by oxidation could increase with temperature, but the increased AOC could affect the biostability of the following processes more significantly in winter than in warm seasons due to the low biodegradation in the pipes and the processes at low temperature. $AOC_{P17}$ was mainly removed by coagulation-sedimentation process, especially in cold season. Rapid filtration could effectively remove AOC only during warm seasons by primarily biodegradation, but biological activated carbon filtration could remove AOC in all seasons by biodegradation during warm season and by adsorption and bio-regeneration during cold season. The adsorption by granular activated carbon and anthracite showed inverse relationship with water temperature. The advanced treatment can contribute to enhance the biostability in the distribution system by reducing AOC formation potential and helping to maintain stable residual chlorine after post-chlorination.

Role of the HPV DNA Test in Follow-up of Treated Cervical Intraepithelial Neoplasia in Bangladesh

  • Nessa, Ashrafun;Rashid, Mohammad Harun Ur;Jahan, Munira;Ferdous, Noor-E;Nahar, Pervin Akhter Shamsun;Chowdhury, Afroza
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.19
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    • pp.8063-8067
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    • 2014
  • Background: Cervical cancer is a major public health problem in Bangladesh. Persistence of high risk human papillomavirus (HRHPV) influences the progression of the disease, with an important role in followup for cervical intraepithelial neoplasia (CIN). Objective: To establish application of high risk HPV DNA test in the follow-up of women after treatment of CIN. Materials and Methods: This cross-sectional and hospital based study was carried out among 145 CIN treated women during the previous six months to three years at the colposcopy clinic of Bangabandhu Sheikh Mujib Medical University, Dhaka, between January 2011 and June 2012. Pap smear and HPV samples were collected and colposcopy was performed to find out the persistence of the disease. Cervical samples obtained were tested for HPV DNA using the Hybrid Capture II (HC-II) test. A cervical biopsy was collected whenever necessary. The results were compared to assess the efficacy of different methods during follow up such as Pap smear, HPV test and colposcopy. Results: Mean age of the recruited women (n=145) was 33.6 (${\pm}7.6$), mean age of marriage was 16.8 (${\pm}2.9$) and mean age of 1st delivery was 18.8 (${\pm}3.5$) years. More than half had high grade CIN before treatment and 115 (79.3%) women were managed by LEEP and 20.7% were managed by cold coagulation. Among the 145 treated women, 139 were negative for HPV DNA and six of them (4.1%) were HPV positive. Sensitivity of Pap smear (40.0) and HPV DNA test (40.0) was poor, but specificity was quite satisfactory (>93.0) for all the tests. Conclusions: The high risk HPV DNA test can be an effective method of identifying residual disease. It can be added to colposcopy and this should be applied to all treated women attending for their first or second post-treatment follow-up visit at 6 months to one year, irrespective of the grade of treated CIN.

Improvement of Medium and Small Urban Stream Water Quality and Applicability of Design Factor Using Biological and Physicochemical Processing (도심지역 내 중·소하천 수질 개선을 위한 가압부상 및 관로형 미생물 부착 공정 적용에 관한 연구)

  • Kim, Moon-Ki;Choi, Jung-Su;Kim, Sam-Ju;Kim, Hyun-Gu
    • Journal of Korean Society of Environmental Engineers
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    • v.35 no.7
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    • pp.509-517
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    • 2013
  • The purpose of this study is to assess the applicability of device-type stream coagulation process which combines physiochemical, biological processing for efficient improvement of water quality in small, middle-sized urban streams. The stream purification facility of this study is compose of pressure flotation type Micro Bubble Process(MBP) to remove TSS and TP and conduit line type Attached Microbial Pipe System(AMPS) to remove BOD. Test conditions of each device were set by floating stay time and change of ultra fine bubble injection amount of MBP, and change of AMPS stay time. Also, removal efficiency of pollution sources of each process were assess by change of season. As result of continuous operation of each process, MBP showed a maximum of TSS 83.69%, TP 95.15% process efficiency and AMPS showed a maximum of 52.95% TBOD5 removal efficiency. Also as result of circular operation of each process, MBP showed a maximum of TSS 69.75%, TP 70.17% process efficiency and AMPS showed a maximum of 68.58% TBOD5 removal efficiency. Therefore, it is considered that this stream coagulation process is effective in improving the water quality of streams in urban areas.

Removal of Cs and Sr in Water Using Chemical and Natural Coagulants (화학 및 천연 응집제를 이용한 수중 Cs, Sr 제거)

  • Kim, Seongbeom;Kim, Youngsug;Kang, Sungwon;Oh, Daemin;Lee, Wontae
    • Journal of Korean Society of Environmental Engineers
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    • v.38 no.12
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    • pp.662-666
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    • 2016
  • This study investigated removal of radionuclides (Cs, Sr) in surface water by coagulation and precipitation. Jar tests were conducted with various chemical and natural coagulants to remove the stabilized radionuclides ($^{133}Cs$, $^{88}Sr$). Chemical coagulants included aluminum sulfate, poly aluminum chloride, and poly aluminum hydroxide chloride silicate (PACS); natural coagulants (minerals) included illite and zeolite. Chemical coagulant alone could achieve removals of Cs and Sr less than 10%; The removals increased up to 23.1% for Cs and 17.8% for Sr with addition of poly-dimethyldiallylammonium chloride (polyDADMAC) along with the chemical coagulants. Compared with chemical coagulants, natural coagulants (minerals) could achieve higher removals of Cs and Sr. Addition of zeolite along with PACS and polyDADMAC increased the removal rates up to 36.9% for Cs and 17.1% for Sr.

Reasonable necessity of preoperative laboratory tests in office-based oral and maxillofacial surgery

  • Mi Hyun Seo;Mi Young Eo;Kezia Rachellea Mustakim;Buyanbileg Sodnom-Ish;Hoon Myoung;Soung Min Kim
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.49 no.3
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    • pp.142-147
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    • 2023
  • Objectives: As medical history before surgery is often based on patient reporting, there is the possibility that patients intentionally hide underlying diseases or that dentists cannot recognize abnormal health states. Therefore, more professional and reliable treatment processes are needed under the Korean dental specialist system. The purpose of this study was to elucidate the necessity of a preoperative blood testing routine prior to office-based surgery under local anesthesia. Patients and Methods: Preoperative blood lab data for 5,022 patients from January 2018 to December 2019 were assembled. Study participants were those who underwent extraction or implant surgery under local anesthesia at Seoul National University Dental Hospital. Preoperative blood tests included complete blood count (CBC), blood chemistry, serum electrolyte, serology, and blood coagulation data. Values outside of the normal range were considered an "abnormality," and the percentage of abnormalities among the total number of patients was calculated. Patients were divided into two groups based on the presence of underlying disease. The rates of abnormalities in the blood tests were compared between groups. Chi-square tests were performed to compare data from the two groups, and P<0.05 was considered statistically significant. Results: The percentages of males and females in the study were 48.0% and 52.0%, respectively. Of all patients, 17.0% (Group B) reported known systemic disease, while 83.0% (Group A) reported no specific medical history. There were significant differences between Groups A and B in CBC, coagulation panel, electrolytes, and chemistry panel (P<0.05). In Group A, the results of blood tests that required a change in procedure were identified even though the proportion was very small. Conclusion: Preoperative blood tests for office-based surgery can detect underlying medical conditions that are difficult to identify from patient history alone and can prevent unexpected sequelae. In addition, such tests can result in a more professional treatment process and build patient confidence in the dentist.

Clinical Analysis of Ventilator-associated Pneumonia (VAP) in Blunt-chest-trauma Patients (흉부둔상환자에서 인공호흡기 관련 폐렴환자의 임상적 분석)

  • Oh, Joong Hwan;Park, Il Hwan;Byun, Chun Sung;Bae, Geum Suk
    • Journal of Trauma and Injury
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    • v.26 no.4
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    • pp.291-296
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    • 2013
  • Purpose: Prolonged ventilation leads to a higher incidence of ventilator-associated pneumonia (VAP), resulting in weaning failure and increased medical costs. The aim of this study was to analyze clinical results and prognostic factors of VAP in patients with blunt chest trauma. Methods: From 2007 to 2011, one hundred patients undergoing mechanical ventilation for more than 48 hours were divided into two groups: a VAP-negative group, (32 patients, mean age; 53 years, M:F=25:7) and a VAP- positive group, (68 patients, mean age; 60 years, M:F=56:12). VAP was diagnosed using clinical symptoms, radiologic findings and microorganisms. The injury severity score (ISS), shock, combined injuries, computerized tomographic pulmonary findings, transfusion, chronic obstructive lung disease (COPD), ventilation time, stay in intensive care unit (ICU) and hospital stays, complications such as sepsis or disseminated intravascular coagulation (DIC) and microorganisms were analyzed. Chi square, t-test, Mann-Whitney U test and logistic regression analysies were used with SPSS 18 software. Results: Age, sex, ISS, shock and combined injuries showed no differences between the VAP - negative group and - positive group (p>0.05), but ventilation time, ICU and hospital stays, blood transfusion and complications such as sepsis or DIC showed significant differencies (p<0.05). Four patients(13%) showed no clinical symptoms eventhough blood cultures were positive. Regardless of VAP, mortality-related factors were shock (p=0.036), transfusion (p=0.042), COPD (p=0.029), mechanical ventilation time (p=0.011), ICU stay (p=0.032), and sepsis (p=0.000). Microorgnisms were MRSA(43%), pseudomonas(24%), acinetobacter(16%), streptococcus(9%), klebsiela(4%), staphillococus aureus(4%). However there was no difference in mortality between the two groups. Conclusion: VAP itself was not related with mortality. Consideration of mortality-related factors for VAP and its aggressive treatment play important roles in improving patient outcomes.

A Study on the Particle Separation Technology of Contaminated Dredged Sediments (오염 준설퇴적토의 입자분리기술에 관한 연구)

  • Park, Jeong Jun;Hwnag, Soon Gab;Shin, Eun Chul
    • Journal of the Korean Geosynthetics Society
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    • v.12 no.3
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    • pp.87-94
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    • 2013
  • As sediment contamination problems have recently been raised in Korea, the need for technologies to remove contaminants in sediments has increased. Contaminated sediments in Korea has been annually dredged and treated using processes of coagulation/flocculation, sedimentation on barges, dewatered and dried at prepared site, and then disposed at a landfill site, which is very costly, and only a limited landfill space available in Korea. Contaminants in media containing a high percentage of silt and clay sized particles, typically, are strongly adsorbed on the particles and difficult to remove. Particle separation processes that separate the fine clay and silt particles from the coarser sand and gravel and concentrate the contaminants into a smaller volume of sediment that can be further treated of disposed of, are very effective in the post step processes. In this study are to test the feasibility of treating dredged sediments using a hydrocyclone process, and to estimate design parameters for a pilot scale test. A hydrocyclone was operated to separate larger particles from the sediments. It was found that the particle separation was greatly affected by the solid contents and inlet pressure in the hydrocyclone.

Optimization of Ingot Mold Design Parameters for Austenite Heat-resistant Steel Through Computational Simulation (전산모사를 통한 오스테나이트계 내열강용 잉곳 몰드 설계 파라미터 최적화)

  • Hwang, SooBeen;Park, JongHwa;Jo, SangHyun;Park, SeongIk;Kim, YunJae;Kim, Donggyu
    • Journal of Korea Foundry Society
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    • v.42 no.1
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    • pp.3-11
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    • 2022
  • In this study, the parameters on the shrinkage defect of HR3C alloy was secured through computer simulation research, and the ingot mold with greater than 85% of sound area was designed and manufactured. Moreover, the optimized coagulation was proposed at design stage through computer simulation and test was performed upon ingot manufactured. After the test, the defect pattern was analyzed through cutting and non-destructive inspection to verify the parameter and ingot mold design. Based on the verification results, shrinkage defect parameters such as Niyama, Feed Efficiency, and Hot Tear Intensity of HR3C Alloys were obtained. In addition, through the secured parameters, a plan for designing ingot mold with a Non-defect area of 85% or more was secured.

On-line Monitoring of the Flocs in Mixing Zone using iPDA in the Drinking Water Treatment Plant (정수장 응집혼화공정에서의 응집플럭 연속 모니터링)

  • Ga, Gil-Hyun;Jang, Hyun-Sung;Kim, Young-Beom;Kwak, Jong-Woon
    • Journal of Korean Society of Environmental Engineers
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    • v.31 no.4
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    • pp.263-271
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    • 2009
  • This study evaluated the flocs forming characteristics in the mixing zone to increase the coagulation effect in the drinking water plant. As a measuring tool of formed flocs, on-line particle dispersion analyzer (iPDA) was used in Y drinking water plant. To evaluate the forming flocs, many parameters such as poly amine, coagulant dosing amount, raw water turbidity, and pH was applied in this study. During the periods of field test, poly aluminium chloride (PACl) as a coagulant was used. With the increase of the raw water turbidities, poly amine was also added as one of aids for increasing in coagulation efficiency. The turbidity and pH of raw water was ranged from 7 to 9 and from 25 to 140 NTU, respectively. The increasing of raw water turbidity brought the bigger floc sizes accordingly. From a regression analysis, $R^2$ value was 0.8040 as a function of T, raw water turbidity. Floc size index (FSI) was obtained from a correlation equation as follows; FSI = 0.9388logT - 0.3214 Also, polyamine gave the bigger flocs the moment it is added to the coagulated water in the rapid mixing zone. One of parameters influencing the floc sizes was the addition of powdered active carbon(PAC) in the mixing zone. In case of higher turbidity of raw water, $R^2$ value was 0.9050 in the parameters of [PACl] and [PAC]; FSI = $0.0407[T]^{0.324}[PACI]^{0.769}[PAC]^{0.178}$ On-line floc monitor was beneficial to evaluate the flocs sizes depending on the many parameters consisting raw water properties, bring the profitable basic data to control the mixing zone more effectively.