• 제목/요약/키워드: Co-laboratory

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독수리(Aegypius monachus)의 흡입마취에서 Capnography를 이용한 호기말 이산화탄소분압 모니터링 (Capnographic Monitoring of End-Tidal Partial Pressure of Carbon Dioxide in Anesthetized Cinereous vultures (Aegypius monachus))

  • 박원규;석성훈;박세진;이승용;김영기;황재민;정동혁;이희천;연성찬
    • 한국임상수의학회지
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    • 제32권4호
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    • pp.380-384
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    • 2015
  • The relationships between end-tidal partial pressure of carbon dioxide ($P_{ET}CO_2$) and arterial partial pressure of carbon dioxide ($P_aCO_2$), and between $P_{ET}CO_2$ and blood pH in isoflurane-anesthetized cinereous vultures were evaluated. Nine cinereous vultures (weighing 7.3-9.5 kg) were anesthetized via mask with isoflurane, intubated, and connected to a mechanical ventilator. By mechanical ventilator, respiratory rate was altered to achieve a $P_{ET}CO_2$ randomly selected among 30 to 35 mmHg. $P_aCO_2$ and blood pH were determined in serial arterial samples and compared with concurrent $P_{ET}CO_2$ measured with a sidestream capnography. Thirty six samples, nine cinereous vultures were tested 4 times each, were used to determine correlations coefficients between $P_aCO_2$ and $P_{ET}CO_2$, and between $P_{ET}CO_2$ and blood pH. Strong correlations were observed between $P_aCO_2$ and $P_{ET}CO_2$ (r = 0.951, P = 0.000, y = 1.679x - 30.236, $R^2=0.905$) as well as between $P_{ET}CO_2$ and blood pH (r = -0.728, P = 0.000, y = -0.024x + 8.389, $R^2=0.530$) with Pearson's correlation coefficient and simple linear regression. These results suggest that the capnography used provided a sufficiently accurate estimation of $P_aCO_2$ and blood pH. Thus, the monitoring of $P_{ET}CO_2$ can be useful method to prevent hypoventilation for cinereous vultures receiving mechanical ventilation.

Identification and functional prediction of long non-coding RNAs related to oxidative stress in the jejunum of piglets

  • Jinbao Li;Jianmin Zhang;Xinlin Jin;Shiyin Li;Yingbin Du;Yongqing Zeng;Jin Wang;Wei Chen
    • Animal Bioscience
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    • 제37권2호
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    • pp.193-202
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    • 2024
  • Objective: Oxidative stress (OS) is a pathological process arising from the excessive production of free radicals in the body. It has the potential to alter animal gene expression and cause damage to the jejunum. However, there have been few reports of changes in the expression of long noncoding RNAs (lncRNAs) in the jejunum in piglets under OS. The purpose of this research was to examine how lncRNAs in piglet jejunum change under OS. Methods: The abdominal cavities of piglets were injected with diquat (DQ) to produce OS. Raw reads were downloaded from the SRA database. RNA-seq was utilized to study the expression of lncRNAs in piglets under OS. Additionally, six randomly selected lncRNAs were verified using quantitative real-time polymerase chain reaction (qRT-PCR) to examine the mechanism of oxidative damage. Results: A total of 79 lncRNAs were differentially expressed (DE) in the treatment group compared to the negative control group. The target genes of DE lncRNAs were enriched in gene ontology (GO) terms and Kyoto encyclopedia of genes and genomes (KEGG) signaling pathways. Chemical carcinogenesis-reactive oxygen species, the Foxo signaling pathway, colorectal cancer, and the AMPK signaling pathway were all linked to OS. Conclusion: Our results demonstrated that DQ-induced OS causes differential expression of lncRNAs, laying the groundwork for future research into the processes involved in the jejunum's response to OS.

Complete Genome Sequence of Salmonella enterica Serovar Pullorum Multidrug Resistance Strain S06004 from China

  • Li, Qiuchun;Hu, Yachen;Wu, Yinfei;Wang, Xiaochun;Xie, Xiaolei;Tao, Mingxin;Yin, Junlei;Lin, Zhijie;Jiao, Yang;Xu, Lijuan;Jiao, Xinan
    • Journal of Microbiology and Biotechnology
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    • 제25권5호
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    • pp.606-611
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    • 2015
  • As Salmonella enterica serovar Pullorum remains a major economic problem for the poultry industries of countries with no efficient control measures, we presented a multidrug resistance strain S06004 (isolated from a clinically sick chicken in China in 2006) for genome sequencing. The genome comparison showed that the strain contained two prophages, the ST104 and prophage-4 (Fels2) of E. coli LF82, which were not detected in the only published genomes of S. Pullorum RKS5078 and CDC1983-67. In addition, the GyrA Ser83 point mutation, drugresistant genes, and many antibiotic pump systems that are present in S06004 may be contributing to the multidrug resistance of this strain.

THE PREPARTION AND CHAEATERIZATION OF ALUMINA UF MEMBRANE BY SOL-GEL PROCESS

  • Choi, Y. H.;Paik, J. S.;Kim, H. C.;Lee, S. B.;Oh-kim, E. O.
    • 한국막학회:학술대회논문집
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    • 한국막학회 1991년도 추계 총회 및 학술발표회
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    • pp.29-33
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    • 1991
  • Alumina UF membranes were prepared by sol-gel process and their gas permeabilities were characterized. Alumina MF membrane with average pore diameter about 0.12$\mu$m and tubular shape was used as a support. Gas permeation measurements of helium and nitrogen gas exhibited the permeabilities of 1.58 $\times$ 10E-6 and $0.63 \times 10E-6 cc\cdot cm(STP)/cm^2\cdot sec \cdot cmHg$, respectively. The permeability ratio was 2.5. This means the gas permeation is fully governed by knudsen diffusion mechanism.

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소염효소제(消炎酵素劑)의 약제학적(藥劑學的) 연구(硏究) (Pharmaceutical Studies on Anti-inflammatory Enzyme Preparations)

  • 이강춘;양중익;민신홍;이상의;김용배
    • Journal of Pharmaceutical Investigation
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    • 제8권1호
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    • pp.27-36
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    • 1978
  • Spherical granules of anti-inflammatory enzyme were prepared by mixer granulation and the recovery rate of enzyme activity by processing was compared with tablet ones. In the enteric granule coating .processing, the effect of the amount of coating solution and the conentration of fatty alcohol on disintegration and stabilities on the accelerated conditions were also studied. Being prepared in non-pressure and non-aqueous condition, spherical granules of enzyme made better recovery of enzme activity than tablet ones by 10 times. Combined processing of both mixer granulation and enteric granule film coating provided the noble enteric coated granules, in the sense of disintegration and stabilities, was obtained from using 0.125% fatty alcohol in coating solution.

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Flyback Transformer를 갖는 Switched Reluctance Motor의 구동회로 (Drive Circuit for Switched Reluctance Motor with Flyback Transformer)

  • 임준영;조관열;백인철;신두진;김정철
    • 대한전기학회:학술대회논문집
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    • 대한전기학회 1993년도 하계학술대회 논문집 B
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    • pp.833-836
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    • 1993
  • A flyback type power converter circuit for switched reluctance motor drives is presented. In this converter circuit, the energy extracted from an off going phase is stored in an additional capacitor. The energy stored is used to either be returned to the source frequently or energize the conducting phase during the conduction interval through the transformer. The additional switch to pass the energy stored in the capacitor to the source or the conducting phase is switched under a relatively low voltage condition. Its switching frequency is relatively high so that the size of the transformer can be reduced. The design guideline for the capacitor and the transformer is described. The effectiveness of the presented converter circuit is compared to other circuits through the analysis and experiment.

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