• Journal of Dairy Science and Biotechnology
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• 제27권1호
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• pp.1-12
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• 2009

In 2008, baby formula containing melamine was found to be responsible for a large outbreak of renal failure in infants in China. A total of 294,000 infants were hospitalized, and at least 6 babies died due to ingestion of the tainted formula. Melamine contains high levels of nitrogen (>60%), which is used as an indicator of protein content. Therefore, high levels of melamine in infant formula were thought to be the result of deliberate contamination m an attempt to increase its apparent protein content. Following inspections by China's national inspection agency, assorted products from at least 22 dairy manufacturers across China were found to have varied levels of melamine (range: 0.096196.61 mg/kg). Melamine co-exposure with cyanuric acid can induce acute melamine-cyanurate crystal nephropathy, which can lead to renal failure at much lower doses than if either compound were ingested alone. However, currently, there are very few data on melamine analogues other than cyanuric acid. At an expert meeting of the WHO and FAO held to review toxicological aspects of melamine and cyanuric acid on December 14, 2008, a new tolerable daily intake (TDI) of melamine was established that could be applied to the entire population, including infants. Therefore, a risk assessment of the various theoretical melamine contamination levels in infant formula and selected representative foods (other than infant formula and sole-source nutrition products) is urgently needed for Korean babies and children up to 7 years of age. Although the undetectable level regulation for infant formula may be low enough to guarantee the safety of babies under the age of 1 year (including premature babies), the melamine standard of 2.5 ppm for foods other than baby formula could be insufficient to protect the 95th percentile population aged 1~2 years because of this demographic's high consumption of milk, yogurt, and soy milk (hazard index = 1.79). Because TDIs are chronic values intended to protect an individual over his/her lifetime, occasional modest ingestion in excess of the TDI is not likely to be a health concern. However, children aged 1~2 years may have renal systems that are comparatively more sensitive to the crystallization of melamine and its analogues. Therefore, governmental jurisdictions may need to practice more prudent management of food items that could raise the melamine exposure for this population.

• 자원환경지질
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• 제51권4호
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• pp.371-379
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• 2018

많은 나라에서는 화력발전소 석탄연소 잔재물로 생산되는 석탄재를 소량의 시멘트와 혼합, 저강도 콘크리트를 만들어 지반함몰지, 폐갱도, 도로관거 뒷채움재 등으로 재활용하는 방안이 석탄재의 대규모 처리방안으로 자주 검토된다. 본 연구에서는 석탄재로 저강도콘크리트를 만들어 콘크리트 내 중금속함량 변화를 고찰하였다. 이를 위하여 시멘트만을 사용하는 경우와 시멘트의 반을 비산재로 대체하는 경우, 모래를 골재로 사용하는 경우, 그리고 회처리장의 매립재로 모래골재를 대체하는 경우에 대한 콘크리트 공시체를 제작하여 중금속농도 변화를 고찰하였다. 중금속 함량은 토양오염공정시험기준에 따라 이루어졌으며, 중금속함량에 가장 큰 영향을 주는 재료들도 평가하였다. 연구결과, 시멘트는 다른 어떤 재료들 보다 Cu, Pb, Zn에서 현격히 높은 중금속농도를 보였다. 이로 인하여 시멘트를 비산재로 대체할 경우 중금속 농도는 뚜렷이 낮아지는 경향을 보였다. 매립재는 전체적으로 비산재에 비하여 낮은 중금속농도를 보였지만, 모래보다는 높은 Cu 및 Ni농도와 낮은 Pb농도를 보였다. 전체적으로는 콘크리트 내 중금속농도는 각 재료의 혼합에 의하여 결정되는 양상을 보였다. 본 연구에서 제작된 공시체는 모든 조사된 항목에 있어 토양환경보전법이 정한 토양오염우려기준(1지역)보다 현격히 낮은 농도를 보였다.

• 한국환경농학회지
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• 제40권4호
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• pp.260-269
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• 2021

BACKGROUND: Diquat dibromide is a fast-acting nonselective herbicide and plant growth regulator. In this study, in order to understand the possibility of unintentional pesticide contamination in the following crops, the phytotoxicity and transition of diquat dibromide residue in soil into the following crops such as pepper, radish, lettuce and corn have been assessed through phytotoxicity trial and residual evaluation in the unintentional contamination of the higher residual diquat dibromide. METHODS AND RESULTS: The pepper, radish, lettuce and corn were cultivated in the sandy soil and loam soil where the 35 mg/kg and 90 mg/kg diquat dibromide were applied, respectively. Mild growth inhibition symptoms were observed in radish, lettuce and corn crops at the 90 mg/kg- diquat dibromide treatment on the 30 day of cultivation. Diquat dibromide was analyzed using liquid chromatography QTRAP (LC-MS/MS). The recovery rates of diquat dibromide from soil and crop were determined within range from 89.1 to 116.4% with relative standard deviation less than 14.7%. Diquat dibromide residues in soil were found to be 23.90-30.22 and 69.59-82.57 mg/kg from the 35 mg/kg and 90 mg/kg of diquat dibromide-treated soil, respectively after 30 days of crop cultivation. This result implicates that diquat dibromide did not convert to metabolites and remained mostly in the soil, even though it was partially decomposed during crop cultivation. In addition, the diquat dibromide in pepper and radish that were grown for 47 days, and lettuce and corn that were cultivated for 30 days were detected to be 0.01 mg/kg or less in the sandy loam and loam soil where the 90 mg/kg diquat dibromide was applied. CONCLUSION(S): Diquat dibromide did not cause severe phytotoxicity in the following crops as well as it did not uptake and distribute to the following crops, even though it was considered to be residual in the soil.

• 한국대기환경학회지
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• 제30권3호
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• pp.281-290
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• 2014

This study was conducted to evaluate the distribution characteristics of $PM_{10}$ and heavy metals concentrations in the ambient air of Gyeonggi-do area by region and season from February, 2013 to March, 2014. The regression model for the prediction of formation characteristics and contamination degree of $PM_{10}$ and heavy metals by correlation analysis and regression analysis for using the multivariate statistical analysis was also established. The main wind direction during the investigation period was South East (SE) and West South West (WSW) winds, and the concentration of $SO_2$ at Ansan with industrial region showed 1.6 times higher than Suwon, Euiwang with residential region. The concentrations (median) of Pb, Cu and Ni at Ansan showed 3.2~4.5, 1.9~2.2 and 1.7~2.6 times respectively higher than those at Suwon. By the seasonal concentration variation, the concentrations of $PM_{10}$, Pb, Fe and As in winter and spring (December to May) showed 1.7, 1.9, 1.9 and 2.7 times respectively higher than those in summer and fall (June to November). As, Fe and $PM_{10}$ had a big difference by the seasonal factors, and Cu and Ni were evaluated to be influenced by the regional factors. From the results of correlation analysis among the target items, the correlation coefficient of PM and Mn had 0.82 (p/0.01) and that of Fe and Mn had 0.82 (p/0.01), which showed high correlation. And the correlation coefficients for $SO_2$ and Pb, CO and $PM_{10}$ were 0.66 (p/0.01) and 0.62 (p/0.01) respectively. The multiple linear regression models for $PM_{10}$, Pb, Cu, Cr, As, Ni, Fe and Mn were established by independent variables of CO, $SO_2$ and meteorological factors (wind speed, relative humidity). In the regression models, independent variable $SO_2$ was in cause-and-effect relationship with all dependent variables, and $PM_{10}$, Fe and Mn were influenced by CO and wind speed, and Pb, Cu, Ni and As had a main factor of $SO_2$.

• 한국양식학회지
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• 제11권1호
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• pp.99-103
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• 1998

rotifer의 배양조에 혼재된 Artemia가 rotifer의 증식에 미치는 영향을 검토하였다. 실험에는 Koshiki주의 rotifer, Brachionus rotundiformis와 미국 샌프란시스코의 Great Salt lake주의 Artemia sp.를 사용했다. 그리고 모든 실험은 염분을 22ppt, 배양 온도는 $25^{\circ}C.$, 먹이로서 N. oculata을 2일 간격으로 ml 당 $7{\times}10^5$ 세포씩 공급하면서, 50 ml의 비이커에 N. oculata 현탁액을 40ml씩 넣고, rotifer 20마리 그리고 Artemia는 3마리씩 각 수조에 수용하여 각 생물들을 단일종 배양한 경우와 혼합 배양한 경우의 증식을 비교하였다. rotifer와 Artemia 유생을 혼합 배양한 경우, 두 생물은 한정된 먹이 N. oculata 조건하에서 먹이 경쟁(food competition)을 하였다. 또한, rotifer의 대량 배양조에 Artemia 성체의 급속한 섭식 활동에 의해서 심각한 먹이 부족 현상을 일으켰다. 결국, Artemia 성체는 rotifer의 안정적인 생산을 크게 방해하는 rotifer 증식 억제 요인으로서 작용했다. 즉, rotifer을 안정적으로 생산하기 위해서는 종묘 생산 과정에서 유발될 수 있는 Artemia의 혼재가 일어나지 않도록 각별한 주의가 필요하다.

• 한국조리학회지
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• 제20권6호
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• pp.200-210
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• 2014

본 연구에서는 방울토마토를 이용하여 다양한 온도와 저장기간(0, 7, 그리고 14일) 및 포장재의 기체조성을 달리하여 품질 변화 및 대장균, 곰팡이 그리고 효모와 같은 미생물의 오염도에 관해 분석하였다. 본 연구는 $5^{\circ}C$, $10^{\circ}C$ 그리고 $15^{\circ}C$의 상태에서 0일 7일 그리고 14일간 저장하여 pH, 색도 변화 및 미생물의 성장패턴을 확인하였다. 방울토마토의 pH의 변화에서는 기간에 따른 증가를 확인하였지만, 큰 차이는 보이지 않았다. 또한, 색도를 측정하였을 때도 기체조성과 온도에 독립적으로 밝기와 적색도 그리고 황색도에서 불규칙한 결과를 확인하였다. 미생물은 총균수, 대장균군수, 곰팡이 및 효모를 측정하였다. 혼합가스로 $5^{\circ}C$, $10^{\circ}C$ 그리고 $15^{\circ}C$의 상태에서 저장한 방울토마토의 미생물도 불규칙적인 생장패턴을 확인하였다. 그러나 산소함량에 비해 이산화탄소 함량이 많은 포장재에서 평균적으로 균의 생장 속도를 늦출 수 있는 것을 확인하였다. 따라서 본 연구는 저장이 우수한 최적의 기체조성 및 온도 등의 확립을 위한 기초자료로 제공할 수 있을 것으로 사료된다.

• 생물환경조절학회지
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• 제19권4호
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• pp.343-350
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• 2010

본 연구는 수확시기와 같은 수확 전 요인이 수확 후 신선편이 결구상추의 품질과 미생물 수에 미치는 영향을 구명하기 위하여 수행하였다. 신선편이 가공업체에서 사용하는 결구상추를 5, 6, 7, 10, 12월에 수확하여 관행적인 방법으로 가공한 뒤 필름에 포장하고 $5^{\circ}C$에서 9일 동안 저장하면서 품질 조사를 하였다. 미생물 측정을 위한 샘플은 각 단계별(수확, 수송, 가공전, 절단, 1차-세척, 2차-세척, 저장 후 3, 6, 9일)로 수집되었다. 실험 결과 하우스에서 재배되어 5, 10월에 수확된 결구상추는 신선편이 가공 후 포장백 내부의 $O_2$ 농도가 낮고 $CO_2$는 매우 높았으며, 제품의 전해질 누출이 높게 나타났다. 반면 노지에서 재배된 6, 7월 수확 및 겨울철 하우스재배인 12월에 수확한 원료 는 비교적 낮은 $CO_2$, 전해질 누출 및 갈변을 나타내었다. 원료상태의 미생물수는 7월(6.76 log)에 가장 높았고, 신선편이 가공 후 저장중의 미생물 증식은 5월 시료에서 가장 높게 나타났다. 이상의 결과로부터 신선편이 결구상추를 고온, 저습조건의 노지에서 재배되어 6월 상순에 수확한 원료를 사용한 경우 품질과 미생물적 안전성이 모두 우수하였다. 반면, 하우스에서 재배되어 10월에 수확한 결구상추를 원료로 사용한 경우 가공 전과 후의 미생물적 안전성은 모두 우수하였으나, 이취가 빨리 발생하여 품질특성이 나쁘게 나타났다. 따라서 연중 고품질의 신선편이 결구상추 생산을 위해서는 품질과 안전성을 동시에 제어하고 원료의 환경에 따른 품질유지 기간을 달리 설정할 필요가 있는 것으로 생각된다.

• 한국축산식품학회지
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• 제27권1호
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• pp.127-131
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• 2007

본 연구는 단기 숙성형 생햄의 식중독균 오염 상태와 냉장 및 실온 저장 조건 중 미생물수의 변화를 살펴보기 위하여 실시되었다. 생햄의 등심 원료육에서의 미생물 오염도를 조사한 결과 총균수는 $3.11\;log\;CFU/cm^2$이었고 유산균, Pseudomonas spp., Clostridium perfringens 및 효모와 곰팡이는 모두 2 log 미만이었으나 Enterobacteriaceae가 3.11 log로서 주종균이었다. 생햄 원료 및 10과 $25^{\circ}C$에서 저장 된 제품에서 Salmonella spp., Staphylococcus aureus, Vibrio parahaemolyticus, Clostridium perfringens, Listeria monocytogenes와 Escherichia coli O157:H7 등 6가지 식중독균은 발견되지 않았다. 생햄의 초기 총균수는 3.06 log CFU/g이었으며 90일 후에도 균수 증가는 미미하여 $10^{\circ}C$와 $25^{\circ}C$에서 각각 4.6과 4.69 log CFU/g이었다. 생햄의 저장 중 주 종균은 유산균과 Staphylococcus균이었다.

• 대한한의학회지
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• 제23권1호
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• pp.67-82
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• 2002

Objectives: In recent years, extensive focus has been laid on adulteration of herbal medicine with heavy metals. This may be mainly due to soil contamination by environmental pollution. The objective of this study is to identify the contents of various heavy metals in the blood from Ohjeok-san (Wuji-san) Decoction (OD) treated-rats. Methods: For this study, 13 kinds of metals including essential and heavy metals, i.e. A1, As, Cd, Co, Cr, Cu, Fe, Hg, Mn, Ni, Pb, Se and Zn were analyzed by a slight modification of EP A methods and the following results are obtained. Results: 1. There was no significant difference between the OD-treated groups and control group in liver, kidney, bone, brain and weight, especially no significant difference at the 5th and 10th days in weight and the amount of food intake. 2. The amount of each metal analyzed in the blood were as follows; A1: 2.3~3.07 mg/l, As: 2.90~3.66 mg/l, Cd: 0~0.001 mg/l, Co: 0~0.01 mg/l, Cr: 0.40~043 mg/l, Cu: 0.93~1.88 mg/l, Fe: 414.35~464.46 mg/l, Hg: 0.01 mg/l, Mn: 0.10~0.17 mg/l, Ni: 0.01 mg/l, Pb: 0.03~012 mg/l, Se: 0.73 mg/l, Zn: 3.41~4.13 mg/l by groups, respectively. In control and experimental group, Experimental I and other experimental II, III, IV, and V groups, there were no significant differences. 3. The amount of non-toxic metals (A1, Co, Cu, Fe, Mn, Se, Zn) were $64.1{\pm}7.71{\;}mg/l$ in the control group and 60.70~67.58 mg/l in the experimental groups I, II, III, IV and V. The amount of Toxic metals (As, Cd, Cr, Ag, Pb) were $0.68{\pm}0.21{\;}mg/l$ in the control group and 0.57 ~ 0.66mg/l in the experimental groups. The total amount of metals were 32.35 mg/l in the control group and 30.48~34.12 mg/l in the test groups I, II, III, IV and V, respectively. Conclusions: There was no significant difference of metal concentration in the blood from the OD-treated-rats compared to those of the control group even if higher dosage (1~8 times the dosage for a person) of OD was administered. This may be mainly due to a decoction treatment which contains only supernatants filtered from the herb-mass after boiling. This indicates the legal limitation for metal concentration in herbal medicine must be applied according to different treatment methods of herbal medicine.

• 한국안전학회지
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• 제31권3호
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• pp.42-46
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• 2016

In LCD Display or semiconductor manufacturing processes, the anti-static technology of glass substrates and wafers becomes one of the most difficult issues which influence the yield of the semiconductor manufacturing. In order to overcome the problems of wafer surface contamination various issues such as ionization in decompressed vacuum and inactive gas(i.e. $N_2$ gas, Ar gas, etc.) environment should be considered. Soft X ray radiation is adequate in air and $O_2$ gas at atmospheric pressure while UV radiation is effective in $N_2$ gas Ar gas and at reduced pressure. At this point of view, the "vacuum ultraviolet ray ionization" is one of the most suitable methods for static elimination. The vacuum ultraviolet can be categorized according to a short wavelength whose value is from 100nm to 200nm. this is also called as an Extreme Ultraviolet. Most of these vacuum ultraviolet is absorbed in various substances including the air in the atmosphere. It is absorbed substances become to transit or expose the electrons, then the ionization is initially activated. In this study, static eliminator based on the vacuum ultraviolet ray under the above mentioned environment was tested and the results show how the ionization performance based on vacuum ultraviolet ray can be optimized. These vacuum ultraviolet ray performs better in extreme atmosphere than an ordinary atmospheric environment. Neutralization capability, therefore, shows its maximum value at $10^{-1}{\sim}10^{-3}$ Torr pressure level, and than starts degrading as pressure is gradually reduced. Neutralization capability at this peak point is higher than that at reduced pressure about $10^4$ times on the atmospheric pressure and by about $10^3$ times on the inactive gas. The introductions of these technology make it possible to perfectly overcome problems caused by static electricity and to manufacture ULSI devices and LCD with high reliability.