• Title/Summary/Keyword: Clinical review

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Factors associated with willingness to participate in clinical trials for cancer patients: an exploratory narrative review (암 환자의 임상시험 참여 의향과 연관된 요인: 탐색형 서술적 문헌고찰)

  • Kim, Kun Hyung;Hwang, Bo Yown;Son, Gyung Mo
    • Journal of Acupuncture Research
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    • v.33 no.3
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    • pp.145-152
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    • 2016
  • Objectives : This study aimed to investigate both cancer patients' willingness to participate (WTP) in clinical trials and its associated factors. Methods : We searched MEDLINE (PubMed) for studies that had investigated cancer patients' WTP in clinical trials. Search terms included 'willingness to participate', 'cancer' and 'trial'. Studies published within the last five years up to July 26, 2016 were potentially eligible. Results : Of 44 initial hits, 14 studies (12 quantitative and 2 qualitative) were included. Two out of the 14 studies investigated WTP in an acupuncture trial. Study designs, such as WTP measurement methods, investigation settings, and type of cancer, varied. The proportion of participants with a WTP was widely distributed between the studies (median 48.6 %, range 11.1 % to 88.3 %). Factors associated with WTP included various socio-demographic factors, clinical factors, participants' knowledge/attitudes toward clinical trials, travel distance, information from physicians, and trust toward physicians. Conclusion : WTP and its associated factors were variable across the reviewed studies, which might be due to different research methods and contexts. Whether or not common factors associated with cancer patients' WTP in clinical trials exist remains unclear and thus warrants further research.

The Change of Basic and Postgraduate Medical Education after Intern Training System Dismantling (인턴수련제도 폐지에 따른 기본의학교육-졸업 후 의학교육의 변화)

  • Kim, Byung Soo
    • Korean Medical Education Review
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    • v.15 no.2
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    • pp.69-74
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    • 2013
  • This study aimed to review the expected changes in the medical educational environment and to evaluate approaches to coping with the abolition of the postgraduate intern training system. It is expected that after the intern training system is dismantled, postgraduate medical students will be deprived of the opportunity to practice opportunity for clinical practice and to inquire into their medical specialization. Therefore, major improvements in the clinical education curriculum must be made so that students can do so through the clinical education program. Offering students the opportunity to perform clinical practice through the clinical education program might require a revision in the laws and regulations on clinical education as well as the standardization of the clinical education curriculum in line with international practices. Reform measures to provide students the opportunity to inquire their specializations might be the introduction of a medical curriculum containing diverse fields and the establishment of a matching program to assign medical students to their residency programs after medical school. Finally, the fact that the basic concern of postgraduate medical education is the cultivation of primary care physicians must not be forgotten even after the dismantling of the postgraduate intern training system.

Historical Review of Sensory Integration in Korea (감각통합치료의 역사적 고찰)

  • Kim, Kyeong-Mi
    • The Journal of Korean Academy of Sensory Integration
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    • v.1 no.1
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    • pp.73-79
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    • 2003
  • The significant historical events and developments in the area of approach for sensory integration in Korean Society of Sensory Integration Therapists(KSSIT) are reviewed to stimulate future planning and clinical application in professional and health promotion. The paper reviewed the purposes of establishment, the role of members, progress of regular meetings and education for members and seminars in KSSIT. This review is placed within the context of the progressive period of KSSIT history, 1997-2003. Historical data are used as primary sources as records of events in KSSIT's homepage, official transcripts, professional articles, and secondary sources such as news letters for occupational therapists and oral information from first members. This review examined current actions and thinking, and suggests further actions and thinking for progressive professional education programs, research, clinical applications and public relations in sensory integration approach in KSSIT.

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The Effect of Public Report on Antibiotics Prescribing Rate (급성상기도감염 항생제 처방률 공개 효과 분석)

  • Kim, Su-Kyeong;Kim, Hee-Eun;Back, Mi-Sook;Lee, Suk-Hyang
    • Korean Journal of Clinical Pharmacy
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    • v.20 no.3
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    • pp.242-247
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    • 2010
  • Controlling inappropriate antibiotics prescribing for acute upper respiratory infections(URI) is a very important for prudent use of antibiotics and resistance control. Health Insurance Review and Assessment Service (HIRA) introduced Prescribing Evaluation Program and publicly reported antibiotics prescribing rate for URI of each health institution. We performed segmented regression analysis of interrupted time series to estimate the effect of public report on antibiotics prescribing rate using national health insurance claims data. The results indicate that just before the public report period, clinics' monthly antibiotics prescribing rate for URI was 66.7%. Right after the public report, the estimated antibiotics prescribing rate dropped abruptly by 12.3%p. There was no significant changes in month-to-month trend in the prescribing rate before and after the intervention.

A critique: The good and bad of a review

  • McMullen, Debbie;McClean, Rhett;Pak, Sok Cheon
    • CELLMED
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    • v.5 no.3
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    • pp.16.1-16.3
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    • 2015
  • Evidence based medicine involves using both the individual clinician's expertise and the current best available external clinical evidence from systematic research in deciding on the appropriate care for individual patients. The current approach to evidence based practice in healthcare adds a third component which is patient values. Evidence based practice is thus a triad, in which the practitioner's expertise, research evidence and the patient's values are all given consideration. The balance to be struck between them depends on the individual case. The literature indicates that complementary medicine practitioners are moving away from traditional knowledge and towards the use of evidence based practice in their clinical discussions. In the context of the daily practice of complementary medicine practitioners and their continuing development of their knowledge base of evidence based practice, this short review discusses the good and bad of a review journal article.

A Review of Acupuncture Treatment for Infertility

  • Chun, Hea sun;Song, Ho-Sueb
    • Journal of Acupuncture Research
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    • v.38 no.4
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    • pp.257-264
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    • 2021
  • The purpose of this study was to analyze acupuncture treatment methods and acupoint used to treat infertility in the last decade. The data were retrieved from 2010.1 to 2021.8. using national and international electronic databases (PubMed, EMBASE, OASIS, NDSL, and KISS). "Infertility," "sterility," "acupuncture," "electroacupuncture," "bloodletting," "pharmacopuncture," were used as search terms. All studies were mainly concerned with acupuncture treatment of infertility, but the studies which were not related included; (1) infertility or acupuncture treatment; (2) animal studies; (3) review/meta/protocol or clinical study; comparative studies and case reports which were excluded from this review. Only clinical trials for acupuncture treatment of infertility were included in this review (n = 18). For infertility treatment studies using acupuncture, polycystic ovarian syndrome was the main cause of infertility, the most common acupoint used was CV4, CV3, CV6, SP6, BL23, and the treatment effect significantly improved in the group receiving acupuncture treatment compared with the control group, or the group taking Western medicine alone. In some studies, the group using acupuncture treatment did not show side effects. Acupuncture is an effective treatment for infertility.

Criteria for clinical translucency evaluation of direct esthetic restorative materials

  • Lee, Yong-Keun
    • Restorative Dentistry and Endodontics
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    • v.41 no.3
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    • pp.159-166
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    • 2016
  • The purpose of this review was to suggest practical criteria for the clinical translucency evaluation of direct esthetic restorative materials, and to review the translucency with these criteria. For the evaluation of reported translucency values, measuring instrument and method, specimen thickness, background color, and illumination should be scrutinized. Translucency parameter (TP) of 15 to 19 could be regarded as the translucency of 1 mm thick human enamel. Visual perceptibility threshold for translucency difference in contrast ratio (${\Delta}CR$) of 0.07 could be transformed into ${\Delta}TP$ value of 2. Translucency differences between direct and indirect resin composites were perceivable (${\Delta}TP>2$). Universal and corresponding flowable resin composites did not show perceivable translucency differences in most products. Translucency differed significantly by the product within each shade group, and by the shade group within each product. Translucency of human enamel and perceptibility threshold for translucency difference may be used as criteria for the clinical evaluation of translucency of esthetic restorative materials.

Functional Electrical Stimulation : A Review of Clinical Application (기능적 전기자극의 임상 적용에 관한 고찰)

  • Cho, Mi-Suk;Lee, In-Hak;Kim, In-Sup
    • Journal of the Korean Academy of Clinical Electrophysiology
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    • v.4 no.1
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    • pp.39-47
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    • 2006
  • Functional Electrical Stimulation(FES) cause paralysed muscles to contract in some clinical circumstances. Generally, FES has been thought of as a valuable tool in activating any skeletal muscle paralysed as a result of upper motor neuron damage. But, the function of cardiac and smooth muscle is also affected by upper motor neuron damage. Today, various applications of FES are investigated, including conditioning cardiovascular exercise, caugh and breathing assistant, improving bowel and bladder control, hand grasp, standing and walking etc. This review will focus on the literature reporting application of FES to control respiratory capabilities and internal organ function as well as increase muscular strength, hand grasp, standing and walking in patients with upper motor diseases.

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Systemic Review of RCTs focusing on Chronic Fatigue

  • Son, Chang-Gue
    • The Journal of Korean Medicine
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    • v.30 no.6
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    • pp.80-85
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    • 2009
  • Objective: This study aimed to build an overview of randomized clinical controlled trials (RCTs) for chronic fatigue-related symptoms to extract the useful data for management of patients and development of therapeutics using Korean traditional medicine in the future. Methods: All RCT-derived papers for chronic fatigue-related symptoms were collected via PubMed Database. We surveyed elementary information of RCTs such as clinical question, study design, and its quality and results. Results: A total of fifty-three RCTs met these review criteria. Most of the RCTs were performed in Western countries, particularly the UK and USA. The major portion of RCTs focused on chronic fatigue syndrome using immune modulators, psychotherapeutic and anti-depressants. Five RCTs using complementary and alternative medicine, including herbal remedies, showed positive results. Conclusions: Fatigue-related symptoms are a main target of Oriental medicine. This study provides helpful information for planning clinical study of chronic fatigue-related symptoms using traditional Korean medicine.

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Clinical utilization of cord blood over human health: experience of stem cell transplantation and cell therapy using cord blood in Korea

  • Lee, Young-Ho
    • Clinical and Experimental Pediatrics
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    • v.57 no.3
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    • pp.110-116
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    • 2014
  • Cord blood (CB) has been used as an important and ethical source for hematopoietic stem cell transplantation (SCT) as well as cell therapy by manufacturing mesenchymal stem cell, induced pleuripotential stem cell or just isolating mononuclear cell from CB. Recently, the application of cell-based therapy using CB has expanded its clinical utility, particularly, by using autologous CB in children with refractory diseases. For these purposes, CB has been stored worldwide since mid-1990. In this review, I would like to briefly present the historical development of clinical uses of CB in the fields of SCT and cell therapy, particularly to review the experiences in Korea. Furthermore, I would touch the recent banking status of CB.