• Korean Journal of Acupuncture
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• 제32권4호
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• pp.177-189
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• 2015

Objectives : To develop and validate a survey form for adverse events(AEs) associated with acupuncture and moxibustion treatment. Methods : The 1st version of a survey form consisting of 9 categories was developed and modified based on the analysis of questionnaires from previous studies on AEs. To evaluate content validity of the 1st version, a Delphi survey where experts in acupuncture and moxibustion, and research methodology were invited, was conducted alongside a separate content validity questionnaire. The content validity indices for each item and total scale were calculated as the proportion of the number of experts judging each item or scale valid to the number of total experts. Results : After the Delphi round 1, the content validity of 2 items and total scale was rated as inadequate. The 1st version was modified accordingly, and the 2nd version of the survey form was developed. The content validity of the 2nd version was assessed in the Delphi round 2 and the final version was completed after incorporating the expert comments. The final version consists of 13 questions regarding practitioner/patient information, condition/disease, intervention, treated body parts, safety issue and AE occurrence related with practitioner's behavior or instruments, AEs associated with treatment and emergency actions taken if necessary, time to AE occurrence, outcomes, serious AEs or death, and time to AE disappearance. Conclusions : This newly developed and validated survey form will serve to collect AEs associated with acupuncture and moxibustion treatments in Korea and contribute to establishing the evidence on safety of Korean acupuncture treatment.

• 대한치과교정학회지
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• 제45권2호
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• pp.74-81
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• 2015

Objective: The purposes of this study were 1) to classify lingual dental arch form types based on the lingual bracket points and 2) to provide a new lingual arch form template based on this classification for clinical application through the analysis of three-dimensional virtual models of normal occlusion sample. Methods: Maxillary and mandibular casts of 115 young adults with normal occlusion were scanned in their occluded positions and lingual bracket points were digitized on the virtual models by using Rapidform 2006 software. Sixty-eight cases (dataset 1) were used in K-means cluster analysis to classify arch forms with intercanine, interpremolar and intermolar widths and width/depth ratios as determinants. The best-fit curves of the mean arch forms were generated. The remaining cases (dataset 2) were mapped into the obtained clusters and a multivariate test was performed to assess the differences between the clusters. Results: Four-cluster classification demonstrated maximum inter-cluster distance. Wide, narrow, tapering, and ovoid types were described according to the intercanine and intermolar widths and their best-fit curves were depicted. No significant differences in arch depths existed among the clusters. Strong to moderate correlations were found between maxillary and mandibular arch widths. Conclusions: Lingual arch forms have been classified into 4 types based on their anterior and posterior dimensions. A template of the 4 arch forms has been depicted. Three-dimensional analysis of the lingual bracket points provides more accurate identification of arch form and, consequently, archwire selection.

• 사상체질의학회지
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• 제16권3호
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• pp.25-33
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• 2004

1. Objectives Theoretically Healthy Condition of four constitution is based on intact state of four fundamental factors - digestion, urination, perspiration, defecation. Each one of these four factors is specifically related to its respective constitution. We made SHI(Sasangin Health Index) 10 items from four factors, and examined clinical efficacy of the four factors as index of health status in four constitution. 2. Methods and Procedures We offered QSCCII, SHI and SF-36 questionnaires to adults who had a periodic medical examination. 233 adults were classified to one of four constitution. We compared means of 8 scale scores of SF-36, and computed the correlation coefficient between 8 scale scores of SF-36 and 10 item scores of SHI in four constitution. 3. Results In Soyangin, stool volume and frequency are weakly correlated with health status(P<0.05). In Soeumin, appetite is weakly correlated with health status(P<0.05). In Taeumin, there is no correlation between perspiration and health status. 4. Conclusions 2 factors - digestion, defecation - had clinical efficacy as index of health status.

• 대한한방내과학회지
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• 제40권3호
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• pp.541-550
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• 2019

Objective: The aim of this clinical study was to describe the case of a patient who experienced chronic diarrhea related to seasonal changes that improved with herbal medicine treatment. Methods: A patient with diarrhea and globus hystericus was treated following treatment with Hoehyangbanchong-san-hap-Ukgan-san and Gamisachil-tang. A defecation and urination diary, the Bristol Stool Form Scale, and the Visual Analog Scale (VAS) were used to evaluate the effectiveness of this treatment. Results: During treatment, the patient's Bristol Stool Form Scale score changed from Type 7 to Type 4, and the VAS score was significantly decreased. The symptoms of diarrhea and globus hystericus almost subsided. Conclusion: In this case, Korean traditional herbal medicine reduced the clinical symptoms of diarrhea and globus hystericus.

• 한국치위생학회지
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• 제19권4호
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• pp.449-465
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• 2019

Xylitol is a sweetening agent used to prevent dental caries. It is formulated and consumed in various forms, and its use is recommended in particular for oral health. However, dental specialists are not familiar with xylitol or well-acquainted with the appropriate method to use it. Furthermore, the caries-prevention effect of xylitol has been controversial. Thus, in this study, we aimed to analyze previously published studies on the dental caries prevention effect of xylitol to verify its true effects and establish an appropriate method to use it. We analyzed 94 clinical research manuscripts obtained from domestic and international online databases and found that although 11 manuscripts reported no significant dental caries prevention effect of xylitol, most manuscripts reported dental caries prevention with xylitol. Compared to the manuscripts that reported dental caries prevention with xylitol, those are assessed lower amounts of xylitol or shorted consumption periods, and had dosage form that could not retain xylitol sufficiently long in the mouth, similar to milk. Thus, consumption of 5-11 g of xylitol in the form of gums, candies, or tablets over a long time period could effectively reduce the risk of dental caries. It has the advantage of ease of consumption, regardless of the gender, age, or disability of the person.

• 대한수의학회지
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• 제40권3호
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• pp.587-599
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• 2000

This study was conducted to observe the severity of the disease and pathogenecity of Babesia gibsoni parasite on the splenectomized dogs(SPD) and nonsplenectomized(intact) dogs (NSPD) experimentally infected with B gibsoni. The average prepatent period was 4 days in the SPD and 8 days in the NSPD, respectively. Peak parasitaemia(PE) ranged from 26% to 34% of erythrocytes infected in the SPD and from 4% to 5% in the NSPD. Latent parasitaemia was still detectable 40 days as low as under 1.0% of erythrocytes infected after the initial parasitaemia in the SPD. Blood packed cell volume(PCV) decreased to as little as 6.4% to 6.9% in the SPD. The clinical signs were mild fever and anemia in the NSPD, remissions and exacervations of temperature, intermittent or spike-like increases of temperature, progressive polychromatophilic macrocytic anemia with anisocytosis, icterus, marked loss of appetite, rarely haemoglobinuria, and deep brown-yellowish urine in the SPD. Gross pathologic changes mainly involved slightly enlargement of liver and spleen in the NSPD and marked enlargement of liver in the SPD. Anatomic changes associated with the disease included diffuse periportal and centrilobular hephatitis, and membranoproliferative glomerulonephritis. Hyaline droplets, resulting protein metabolic alterations, were found in the convoluted ephithelium of the kidney. The density of lymphocytes within the liver sinusoids was markedly increased. Aggregates of large monocytes and macrophages were demonstrated in the centrilobular veins of the liver. The density of these cells in the centrilobular veins were greatest in the SPD. The forms of B gibsoni parasite found in the acute stage of SPD were large signet ring form, small signet ring form, pyriform, elongated form, comma form, head-phone form, oval form, peared form, racket-like form, amoeboid form, triangle form, quartered form, dot form, band form and multiple, and rosette form, et al. The severity of the disease and pathogenecity of B gibsoni parasite were mild in the NSPD but fatal in the SPD.

• Journal of Oral Medicine and Pain
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• 제21권1호
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• pp.141-152
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• 1996

Oral Lichen Planus(OLP) is a idiopathic chronic inflammatory disease with more difficult to clear and higher recurrent rate than cutaneous lesions. But, there has been no estabilished theories about the proper treatment for OLP. The purpose of this study is to examine the clinical feature, relationship with systemic disease and dental treatment of OLP patients of Korea and to gain helpful information about clinical characteristics and treatment of OLP. The subjects chosen for the study were 54 patients who had visited Department of Oral Diagnosis & Oral Medicine at Yonsei University Dental Hospital Dental Hospital and diagnosed as OLP. Previous clinical records has been reviewed and questionnaires, oral examination, laboratory examination were done and recorded. The following results were obtained : 1. Of the 54 patients, 21 were men and 33 were women with an average age of 47.8 years. 2. The most common intraoral site was bilateral buccal mucosa, followed by unilateral buccal mucosa, gingiva, vesibule, lip mucosa, glossal mucosa, palatal mucosa and mouth floor. 3. The mixed, erosive and reticular form of OLP was most frequent(83.3%) clinical form. 4. OLP patients with liver disease were 5, and drug medication patients were 7. But, we could not find its evidence of association with OLP. 5. Associated events on onset of symptom were stress, denture wearing, dental treatemtn, and common cold. 6. Associated symptoms were dry mouth, tingling, sore throat, and altered taste perception. 30.8% of patients had no specific associated symptoms. 7. Aggravating factors of symptom were peppery food, hot food, fatigue, toothpaste, salty food, sour food, tension, and conversation. Reducing factors were cold food, sleeping. 69.2% of patients had no specific reducing factors. 8. There were no significant differences between normal papulation and OLP patients in CBC, SGOT< SGPT, Serum iron, Total iron binding capacity. 66.7% of subjects were positive response to fungus study for Candida Albicans. The incidence of stress and dental treatment on onset of symptom appeared high in OLP patients. Especially, high incidence of positive response to fungus study for Candida albicans, prescription of anti-fungal agents and dental treatment considerations may be helpful to treatment of OLP.

• 한국정보과학회논문지:데이타베이스
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• 제33권2호
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• pp.239-249
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• 2006

병원정보시스템(Hospital Information System)은 다른 병원정보시스템과 서로 독립적으로 운영되므로 상호운영성(Interoperability)이 배제되어 왔다. 이 연구는 HL7 표준임상문서구조(Health Level 7, Clinical Document Architecture)와 XML 스키마의 분석과 설계를 통하여 새로운 패러다임의 병원정보시스템을 제안한다. 퇴원요약지로부터 필수 항목을 규정하여 템플릿을 정의한 후 임상문서구조를 설계하여 자동적으로 임상문서를 생성되도록 하였다. XML 스키마는 HL7에서 정의한 참조정보모델(Reference Information Model)을 기반으로 분석하였고, 전송 프로토콜은 HL7 V2.4를 사용하였다. 본 연구가 가지는 의의는 첫째, 국제 표준인 HL7 표준임상문서구조를 사용하기 위한 확장과 정제과정의 연구를 했으며, 둘째, 표준임상문서구조를 사용할 수 있는 웹 기반의 차세대 병원정보시스템의 구조를 제안하였다. 결론적으로, 한국의 퇴원요약 표준임상문서구조에 대한 본 연구로 말미암아 평생전자의무기록(Electronic Health Record)과 임상데이타저장소(Clinical Data Repository)를 포함하여 다양한 보건의료기관 간 의료정보 공유의 기반이 될 것이다.

• Journal of Acupuncture Research
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• 제30권5호
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• pp.139-153
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• 2013

Background or Objectives : The purpose of this study is to review oriental medicine journal clinical study in human that have been utilize Electroacupuncture in Korea. Methods : We investigated clinical studies in relation to electroacupuncture through 70 articles from OASIS excluded studies used rats and reviews. Results : Of 162 articles, totally 70 articles selected. There was differences ways of stimulation. In 70 articles, 19 type of instrument is used. About Stimulation time, 15 minutes form 40 percent, 20 minute form 37.1 percent, 30 minute form 11.4 percent. About stimulation intensity, there was 20 articles is unknown intensity. Only 21 articles present intensity by value. In frequency, 2 Hz frequency is used the most, 21 articles. Below 10 Hz frequency is used 54.2 % in 70 articles. There was 7 articles is unknown frequency. Conclusions : The result of this study could provide useful information of field of electroacupuncture is used in oriental medicine. Studies of electroacupuncture should be carried out in many different ways.

• Journal of Periodontal and Implant Science
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• 제44권4호
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• pp.201-206
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• 2014

Purpose: Aggressive periodontitis, especially in its severe form, was traditionally considered to have an unfavourable prognosis. It required a complex treatment and its stabilization was often achieved by surgical therapy. The aim of this study was to investigate the results of nonsurgical periodontal treatment in severe generalized forms of aggressive periodontitis. Methods: Patients with advanced generalized aggressive periodontitis were included in the study. Probing depth (PD) of pockets ${\geq}7mm$ and clinical attachment level (CAL) of sites with attachment loss ${\geq}5mm$ were measured at baseline before nonsurgical periodontal treatment, at re-evaluation, and after treatment. The following other parameters were recorded: resolution of inflammation and bone fill. We compared the baseline values with re-evaluation and posttreatment values using the Friedman test. The Wilcoxon test with the Bonferroni correction was used for both re-evaluation and posttreatment values. Results: Seven patients with 266 periodontal sites were examined. A significant difference was found between values, reported as medians with interquartile ranges, for PD at baseline (7.94 [7.33-8.19] mm) and both re-evaluation (4.33 [3.63-5.08] mm) and posttreatment (3.54 [3.33-4.11] mm) values (P=0.002). A significant difference was also found between values for CAL at baseline (9.02 [7.5-9.2] mm) and both re-evaluation (6.55 [6.30-6.87] mm) and posttreatment (6.45 [5.70-6.61] mm) (P=0.002). Inflammation was resolved and angular bone defects were repaired in all cases. Conclusions: These therapeutic results suggest that this form of periodontitis could have positive outcomes after nonsurgical periodontal treatment. The reparative potential of tissue affected by severe aggressive periodontitis should encourage clinicians to save apparently hopeless teeth in cases of this form of periodontitis.