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Outcomes of nonsurgical periodontal therapy in severe generalized aggressive periodontitis

  • Bouziane, Amal (Department of Periodontology, Faculty of Dental Medicine, Biostatistical, Clinical, and Epidemiological Research Laboratory, Faculty of Medicine and Pharmacy, Mohammed V Souissi University) ;
  • Benrachadi, Latifa (Department of Periodontology, Faculty of Dental Medicine, Mohammed V Souissi University) ;
  • Abouqal, Redouane (Biostatistical, Clinical, and Epidemiological Research Laboratory, Faculty of Medicine and Pharmacy, Mohammed V Souissi University) ;
  • Ennibi, Oumkeltoum (Department of Periodontology, Faculty of Dental Medicine, Mohammed V Souissi University)
  • Received : 2014.04.21
  • Accepted : 2014.08.10
  • Published : 2014.08.30

Abstract

Purpose: Aggressive periodontitis, especially in its severe form, was traditionally considered to have an unfavourable prognosis. It required a complex treatment and its stabilization was often achieved by surgical therapy. The aim of this study was to investigate the results of nonsurgical periodontal treatment in severe generalized forms of aggressive periodontitis. Methods: Patients with advanced generalized aggressive periodontitis were included in the study. Probing depth (PD) of pockets ${\geq}7mm$ and clinical attachment level (CAL) of sites with attachment loss ${\geq}5mm$ were measured at baseline before nonsurgical periodontal treatment, at re-evaluation, and after treatment. The following other parameters were recorded: resolution of inflammation and bone fill. We compared the baseline values with re-evaluation and posttreatment values using the Friedman test. The Wilcoxon test with the Bonferroni correction was used for both re-evaluation and posttreatment values. Results: Seven patients with 266 periodontal sites were examined. A significant difference was found between values, reported as medians with interquartile ranges, for PD at baseline (7.94 [7.33-8.19] mm) and both re-evaluation (4.33 [3.63-5.08] mm) and posttreatment (3.54 [3.33-4.11] mm) values (P=0.002). A significant difference was also found between values for CAL at baseline (9.02 [7.5-9.2] mm) and both re-evaluation (6.55 [6.30-6.87] mm) and posttreatment (6.45 [5.70-6.61] mm) (P=0.002). Inflammation was resolved and angular bone defects were repaired in all cases. Conclusions: These therapeutic results suggest that this form of periodontitis could have positive outcomes after nonsurgical periodontal treatment. The reparative potential of tissue affected by severe aggressive periodontitis should encourage clinicians to save apparently hopeless teeth in cases of this form of periodontitis.

Keywords

References

  1. Parameter on aggressive periodontitis. American Academy of Periodontology. J Periodontol 2000;71(5 Suppl):867-9. https://doi.org/10.1902/jop.2000.71.5-S.867
  2. Demmer RT, Papapanou PN. Epidemiologic patterns of chronic and aggressive periodontitis. Periodontol 2000 2010;53:28-44. https://doi.org/10.1111/j.1600-0757.2009.00326.x
  3. Haubek D, Ennibi OK, Poulsen K, Poulsen S, Benzarti N, Kilian M. Early-onset periodontitis in Morocco is associated with the highly leukotoxic clone of Actinobacillus actinomycetemcomitans. J Dent Res 2001;80:1580-3. https://doi.org/10.1177/00220345010800062001
  4. Eickholz P, Kaltschmitt J, Berbig J, Reitmeir P, Pretzl B. Tooth loss after active periodontal therapy. 1: patient-related factors for risk, prognosis, and quality of outcome. J Clin Periodontol 2008;35:165-74. https://doi.org/10.1111/j.1600-051X.2007.01184.x
  5. Dubrez B, Baehni P, Cimasoni G. A case of localized juvenile periodontitis: treatment and 3 years follow-up with superimposable radiographs. J Clin Periodontol 1996;23:557-62. https://doi.org/10.1111/j.1600-051X.1996.tb01824.x
  6. Sewon LA. Rapid bony healing in localized juvenile periodontitis: a case report. Scand J Dent Res 1993;101:371-4.
  7. Novak MJ, Stamatelakys C, Adair SM. Resolution of early lesions of juvenile periodontitis with tetracycline therapy alone: long-term observations of 4 cases. J Periodontol 1991;62:628-33. https://doi.org/10.1902/jop.1991.62.10.628
  8. Mattout P, Moskow BS, Fourel J. Repair potential in localized juvenile periodontitis: a case in point. J Periodontol 1990;61:653-60. https://doi.org/10.1902/jop.1990.61.10.653
  9. Moskow BS. Healing potential in periodontal lesions: localized juvenile periodontitis. J N J Dent Assoc 1986;57:45-51.
  10. Lindhe J, Liljenberg B. Treatment of localized juvenile periodontitis: results after 5 years. J Clin Periodontol 1984;11:399-410. https://doi.org/10.1111/j.1600-051X.1984.tb01338.x
  11. Buchmann R, Nunn ME, Van Dyke TE, Lange DE. Aggressive periodontitis: 5-year follow-up of treatment. J Periodontol 2002;73:675-83. https://doi.org/10.1902/jop.2002.73.6.675
  12. Kamma JJ, Baehni PC. Five-year maintenance follow-up of early-onset periodontitis patients. J Clin Periodontol 2003;30:562-72. https://doi.org/10.1034/j.1600-051X.2003.00289.x
  13. Aimetti M, Romano F, Guzzi N, Carnevale G. One-stage full-mouth disinfection as a therapeutic approach for generalized aggressive periodontitis. J Periodontol 2011;82:845-53. https://doi.org/10.1902/jop.2010.100468
  14. Aimetti M, Romano F, Guzzi N, Carnevale G. Full-mouth disinfection and systemic antimicrobial therapy in generalized aggressive periodontitis: a randomized, placebo-controlled trial. J Clin Periodontol 2012;39:284-94. https://doi.org/10.1111/j.1600-051X.2011.01795.x
  15. Griffiths GS, Ayob R, Guerrero A, Nibali L, Suvan J, Moles DR, et al. Amoxicillin and metronidazole as an adjunctive treatment in generalized aggressive periodontitis at initial therapy or re-treatment: a randomized controlled clinical trial. J Clin Periodontol 2011;38:43-9. https://doi.org/10.1111/j.1600-051X.2010.01632.x
  16. Darby IB, Hodge PJ, Riggio MP, Kinane DF. Clinical and microbiological effect of scaling and root planing in smoker and non-smoker chronic and aggressive periodontitis patients. J Clin Periodontol 2005;32:200-6. https://doi.org/10.1111/j.1600-051X.2005.00644.x
  17. Hughes FJ, Syed M, Koshy B, Marinho V, Bostanci N, McKay IJ, et al. Prognostic factors in the treatment of generalized aggressive periodontitis: I. Clinical features and initial outcome. J Clin Periodontol 2006;33:663-70. https://doi.org/10.1111/j.1600-051X.2006.00966.x
  18. Yek EC, Cintan S, Topcuoglu N, Kulekci G, Issever H, Kantarci A. Efficacy of amoxicillin and metronidazole combination for the management of generalized aggressive periodontitis. J Periodontol 2010;81:964-74. https://doi.org/10.1902/jop.2010.090522
  19. Guerrero A, Griffiths GS, Nibali L, Suvan J, Moles DR, Laurell L, et al. Adjunctive benefits of systemic amoxicillin and metronidazole in non-surgical treatment of generalized aggressive periodontitis: a randomized placebo-controlled clinical trial. J Clin Periodontol 2005;32:1096-107. https://doi.org/10.1111/j.1600-051X.2005.00814.x
  20. Kaner D, Bernimoulin JP, Hopfenmuller W, Kleber BM, Friedmann A. Controlled-delivery chlorhexidine chip versus amoxicillin/metronidazole as adjunctive antimicrobial therapy for generalized aggressive periodontitis: a randomized controlled clinical trial. J Clin Periodontol 2007;34:880-91. https://doi.org/10.1111/j.1600-051X.2007.01122.x
  21. Mestnik MJ, Feres M, Figueiredo LC, Duarte PM, Lira EA, Faveri M. Short-term benefits of the adjunctive use of metronidazole plus amoxicillin in the microbial profile and in the clinical parameters of subjects with generalized aggressive periodontitis. J Clin Periodontol 2010;37:353-65. https://doi.org/10.1111/j.1600-051X.2010.01538.x
  22. Baltacioglu E, Aslan M, Sarac O, Saybak A, Yuva P. Analysis of clinical results of systemic antimicrobials combined with nonsurgical periodontal treatment for generalized aggressive periodontitis: a pilot study. J Can Dent Assoc 2011;77:b97.
  23. Wennstrom A, Wennstrom J, Lindhe J. Healing following surgical and non-surgical treatment of juvenile periodontitis: a 5-year longitudinal study. J Clin Periodontol 1986;13:869-82. https://doi.org/10.1111/j.1600-051X.1986.tb02245.x
  24. Machtei EE, Cho MI, Dunford R, Norderyd J, Zambon JJ, Genco RJ. Clinical, microbiological, and histological factors which influence the success of regenerative periodontal therapy. J Periodontol 1994;65:154-61. https://doi.org/10.1902/jop.1994.65.2.154

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  1. Aggressive Periodontitis Etiology, Pathophysiology, and Treatment: A Recent Review vol.8, pp.1, 2014, https://doi.org/10.5005/jp-journals-10029-1189