• Journal of Korean society of Dental Hygiene
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• v.18 no.2
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• pp.165-175
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• 2018

Objectives: This study aims to examine the factors that influence the organizational citizenship behavior of clinical dental hygienists to use them as basic data for improving effectiveness and efficiency of dental clinics and hospitals. Methods: A self-reported questionnaire was answered by 250 clinical dental hygienists in Seoul, Gyeonggi, Chungcheong, Jeolla and Gyeongsang province areas who were chosen using convenient sampling method from May 1st to June 30th of 2017. The data was analyzed using IBM SPSS/WIN 22.0 factor analysis on clinical dental hygienists' organization citizenship behavior, organizational commitment, empowerment, self-leadership and job satisfaction. T-test and one-way ANOVA were performed for subjects' general characteristics and organizational citizenship behavior, organizational commitment, empowerment, self-leadership and job satisfaction depending on their job characteristics. The mean comparison was drawn using the Scheffe test. Pearson's correlation and multiple regression analysis were performed to examine the relation of clinical dental hygienists' organizational citizenship behavior, organizational commitment, empowerment, self-leadership and job satisfaction Also, the significance level was set at 0.05. Results: Clinical dental hygienists' organizational citizenship behavior was 3.84 points with organizational commitment of 3.27, empowerment of 3.41, self-leadership 3.45 and job satisfaction of 3.57. Factors that influence clinical dental hygienists' organizational citizenship behavior appeared in the order of organizational commitment, job satisfaction, self-leadership, empowerment and job intensity, and the model's explanation power was 45.6%. Conclusions: Clinical dental hygienists' organizational citizenship behavior was correlated to career, organizational commitment, empowerment, self-leadership and job satisfaction, where organizational commitment had the biggest influence. Therefore, clinical dental hygienists organizational citizenship behavior needs further studies and investigtae more ways to promote factors that influence organizational citizenship behavior.

• Journal of the Korea Safety Management & Science
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• v.19 no.4
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• pp.125-132
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• 2017

The purpose of this study was to assess the correlation between attitude of Patient Safety Management(PSM) and practice of PSM and clinical practice satisfaction of nursing students, also identified how these factors attitude and practice of PSM influence on clinical practice satisfaction, eventually aimed to develop education programs to strengthen practice of PSM in nursing students. A descriptive design was used in the study. The multiple regression was used for the study to prove the factors how the attitude and practice of PSM were affected to the clinical practice satisfaction. The study subjects were 226 nursing students. The results show that attitude of PSM mean was 3.71, practice of PSM mean 3.97, the clinical practice satisfaction mean 3.31. Among the general characteristics, clinical practice satisfaction showed significant differences in satisfaction of major(F=5.10, p=.001), the existence of role model(t=2.64, p=.009). Significant positive correlation was found between attitude of PSM, practice of PSM and the clinical practice satisfaction. Practice of PSM(${\beta}=.39$) was shown as the most important factor to affect on the Satisfaction on clinical practice, also the explanation power of value for this study was found 41.1%. Consequently, this study indicates to develop the education program to strengthen practice of PSM. Also process the additional study for the nursing students in other areas.

• Journal of Digital Convergence
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• v.19 no.2
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• pp.275-288
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• 2021

This study was attemted to grasp the factors affecting the clinical decision-making ability of nurse. Data were collected from 156 nurse working in hospital in G-do. Analysis was done using t-test, ANOVA, Pearson correlation coefficient, and Multiple regression with IBM SPSS WIN/25.0. The most influential factor on the subjects' clinical decision-making ability was nursing Research 'very interest', critical thinking tendency, 'master/doctor', clinical experience 'more than 20 years and 1 month', moral behavior, nursing research 'important', 'single', clinical work experience '5 years, 1 month-10 years', department work experience '3 years 1 month-5 years'. The explanatory power was 51.4%. It was significant in that it was confirmed that interest and importance, moral behavior, academic background, and career are variables that influence clinical decision-making ability. The results of this study can be utilized as basic data for the development of intervention plans and programs that can increase clinical decision-making ability in the context of an ethical dilemma. In addition, developing and verifying educational programs that can increase clinical decision-making abilities in ethical dilemmas is needed.

• Clinical and Experimental Reproductive Medicine
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• v.26 no.2
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• pp.271-274
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• 1999

Activated factor XII (FXIIc: Hageman factor) is a central component of the contact activation system of blood coagulation, fibrinolysis, and kinin formation. Although patients deficient in FXIIc (up to 50% of normal) do not show increased bleeding tendency, thrombotic complications were reported in 8% to 10% among these patients. The reduced generation of bradykinin resulting in diminished release of tissue plasminogen activator is proposed as a cause of thrombosis in factor XII (FXII)-deficient patients. Similarly, in patients with elevated levels of circulating antiphospholipid antibodies, hemostasis may be impaired resulting in excessive thrombophilia. Both vascular and placental thromboses because of antiphospholipid antibodies or FXIIc deficiency have been reported to be associated with recurrent fetal loss. We have experienced a case of factor XII deficiency in woman with recurrent spontaneous abortion. So we report this case with a brief review of literatures.

• The Korean Journal of Health Service Management
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• v.6 no.2
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• pp.1-13
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• 2012

The purpose of this study was to investigate the factors that affect the performance of health insurance review department workers of Korean tertiary hospitals, general hospitals and hospitals. A survey was conducted through structured questionnaire for chiefs and members of health insurance review departments of hospitals, and data from 1,064 respondents were utilized in the final analysis. Survey items included general characteristics of the hospitals and health insurance review departments, job satisfaction and organizational commitment as organizational effectiveness. As multiple linear regression results, in the case of chiefs, the most significantly related factor to job satisfaction was a monthly salary. The other related factor was job stress. In the case of members, the most significantly related factor was job stress. The other related factors were more monthly salary, religious believer, and less complex workplace, in order. As organizational commitment, in the case of chiefs, the most significantly related factor was a monthly salary. The other related factor was more clinical experience. In the case of members, the most significantly related factor was job stress. The other related factors were more monthly salary, tertiary hospitals, more age, and less complex workplace, in order.

• Clinical and Experimental Reproductive Medicine
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• v.17 no.2
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• pp.197-202
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• 1990

Early studies demonstrated that seminal plasma has a factor which inhibits fertilizing ability in a reversible manner. The factor can be precipitated by centrifugation at 104000g for 18 hr. The precipitate was applied to a CM cellulose column and eluted with high salt concentration. This fraction possessed antifertilizing activity was applied to a Sephacryl S-200 column according to a modification of the method of Reddy et al. Using such inhibition of in vitro fertilization ability as an assay, we have carried our experiments to purified the factor. When the factor was added to IVF medium, 70-80% of fertilization was inhibited.

• Clinical and Experimental Reproductive Medicine
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• v.4 no.2
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• pp.35-43
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• 1977

A total of 636 patients of primary infertility were analyzed by computer on the basis of statistical evaluation of etiological factors and therapy with the outcome of the pregnancy. In this report, it included the results of the study analyzed the single etioligic factors responsible for the primary infertility with the outcome of the pregnancy. 1. Two hundred and fourty one patients out of a total 636(37.9%) achieved pregnancy. 2. Four hundred and fifty nine patients out of a total 636(72%) had a single etuiologic factor responsible for the primary infertility. 3. One hundred and seventy six patients out of 459 parients (38.3%) who had a single etiologic factor responsible for the primary infertility achieved a pregnancy. 4. The endometriosis was the most frequent responsible factor for the primary infertility. 5. The success rate of the pregnancy was different in each etioligic factor responsible for the primary infertility. The highest success rate of the pregnancy was in the patients who had the intermediate factor responsible for the primary infertility as much as 66.7% of the patients. 6. The expectancy of the pregnancy in terms of the duration of the therapy and the follow-up was variable and depended upon the etiologic factor of the primary infertility.

• Journal of the Institute of Electronics Engineers of Korea CI
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• v.48 no.2
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• pp.28-37
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• 2011

With growing concerns about healthy life recently, although the podiatry which deals with the whole area for diagnosis, treatment of foot and leg, and prevention has been widely interested, research in our country is not active. Also, because most of the previous researches in data analysis performed the quantitative approaches, the reasonable level of reliability for clinical application could not be guaranteed. Clinical data mining utilizes various data mining analysis methods for clinical data, which provides decision support for expert's diagnosis and treatment for the patients. Because the decision tree can provide good explanation and description for the analysis procedure and is easy to interpret the results, it is simple to apply for clinical problems. This study investigate rules of item of diagnosis in disease types for adapting decision tree after collecting diagnosed data patients who are 2620 feet of 1310(males:633, females:677) in shoes clinic (department of rehabilitation medicine, Chungnam National University Hospital). and we classified 15 foot diseases followed factor of 22 foot diseases, which investigated diagnosis of 64 rules. Also, we analyzed and compared correlation relationship of characteristic of disease and factor in types through made decision tree from 5 class types(infants, child, adolescent, adult, total). Investigated results can be used qualitative and useful knowledge for clinical expert`s, also can be used tool for taking effective and accurate diagnosis.

• Asian-Australasian Journal of Animal Sciences
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• v.21 no.7
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• pp.1003-1010
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• 2008

The objective of the present study was to identify differences in the expression levels of liver proteins between healthy and ketotic cows, establish a liver metabolic interrelationship of ketosis and elucidate the metabolic characteristics of the liver during ketosis. Liver samples from 8 healthy multiparous Hostein cows and 8 ketotic cows were pooled by health status and the proteins were separated by two-dimensional-electrophoresis (2D-E). Statistical analysis of gels was performed using PDQuest software 8.0. The differences in the expression levels of liver proteins (p<0.05) between ketotic and healthy cows were identified by matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF-TOF) tandem mass spectrometry. Five enzymes/proteins were identified as being differentially expressed in the livers of ketotic cows: expression of 3-hydroxyacyl-CoA dehydrogenase type-2 (HCDH), acetyl-coenzyme A acetyltransferase 2 (ACAT) and elongation factor Tu (EF-Tu) were down-regulated, whereas that of alpha-enolase and creatine kinase were up-regulated. On the basis of this evidence, it could be presumed that the decreased expression of HCDH, which is caused by high concentrations of acetyl-CoA in hepatic cells, in the livers of ketotic cows, implies reduced fatty acid ??oxidation. The resultant high concentrations of acetyl-CoA and acetoacetyl CoA would depress the level of ACAT and generate more ??hydroxybutyric acid; high concentrations of acetyl-CoA would also accelerate the Krebs Cycle and produce more ATP, which is stored as phosphocreatine, as a consequence of increased expression of creatine kinase. The low expression level of elongation factor Tu in the livers of ketotic cows indicates decreased levels of protein synthesis due to the limited availability of amino acids, because the most glucogenic amino acids sustain the glyconeogenesis pathway; thus increasing the level of alpha-enolase. Decreased protein synthesis also promotes the conversion of amino acids to oxaloacetate, which drives the Krebs Cycle under conditions of high levels of acetyl-CoA. It is concluded that the livers of ketotic cows possess high concentrations of acetyl-CoA, which through negative feedback inhibited fatty acid oxidation; show decreased fatty acid oxidation, ketogenesis and protein synthesis; and increased gluconeogenesis and energy production.

• The Korean Journal of Physiology and Pharmacology
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• v.21 no.4
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• pp.361-370
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• 2017

Previous reports have suggested that physical and psychological stresses may trigger fibromyalgia (FM). Stress is an important risk factor in the development of depression and memory impairments. Antidepressants have been used to prevent stress-induced abnormal pain sensation. Among various antidepressants, tianeptine has been reported to be able to prevent neurodegeneration due to chronic stress and reverse decreases in hippocampal volume. To assess the possible effect of tianeptine on FM symptoms, we constructed a FM animal model induced by restraint stress with intermittent cold stress. All mice underwent nociceptive assays using electronic von Frey anesthesiometer and Hargreaves equipment. To assess the relationship between tianeptine and expression levels of brain-derived neurotrophic factor (BDNF), cAMP response element-binding protein (CREB), and phosphorylated cAMP response element-binding protein (p-CREB), western blotting and immunohistochemistry analyses were performed. In behavioral analysis, nociception tests showed that pain threshold was significantly decreased in the FM group compared to that in the control group. Western blot and immunohistochemical analyses of medial prefrontal cortex (mPFC) and hippocampus showed downregulation of BDNF and p-CREB proteins in the FM group compared to the control group. However, tianeptine recovered these changes in behavioral tests and protein level. Therefore, this FM animal model might be useful for investigating mechanisms linking BDNF-CREB pathway and pain. Our results suggest that tianeptine might potentially have therapeutic efficacy for FM.