• 한국치위생학회지
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• 제18권2호
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• pp.239-251
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• 2018

Objectives: The purpose of this study was to investigate the effects of dental hygiene students' clinical practice stress, satisfaction and major satisfaction on career preparation behaviors. Methods:This study was conducted targeting the dental hygiene students who have clinical practice experience. The final 305 subjects were analyzed using SPSS 22.0 program. Results: The correlation between clinical practice stress and career satisfaction and career preparation behavior decreases with the higher degree of clinical practice and career preparation behavior. Analysis results about the affecting factors on the level of satisfaction with major satisfaction factors showed the highest factor of preparation behavior, followed by clinical practice and clinical practice stress in order. Analysis results about the affecting factors on the showed the highest factor of preparation behavior, followed by clinical practice and clinical practice stress in order. Conclusions: The results of this study showed that the higher the satisfaction of clinical practice and the higher the satisfaction of career, the more positive the career preparation behavior. Therefore, it's recommended to support continuous education programs to be coherent with dental hygiene student's career preparation behavior based on reinforcing individual competency by obtaining self-confidence and satisfaction from clinical practice.

• 한국융합학회논문지
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• 제9권11호
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• pp.569-579
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• 2018

본 연구는 간호대학생의 핵심기본간호술의 임상수행 경험과 자신감, 임상수행능력 정도를 알아보기 위한 연구이다. 자료는 빈도와 백분율, 평균과 표준편차, t-test, ANOVA, Pearson's Correlation Coefficient, 다중회귀분석을 통하여 분석하였다. 연구결과는 다음과 같다. 핵심기본간호술의 임상수행경험, 수행자신감 및 임상수행능력에서 유의한 차이를 보인 일반적 특성은 학년이며, 임상수행능력과 핵심기본간호술 수행경험 그리고 수행자신감은 순상관관계가 있었다. 임상수행능력에 가장 큰 영향을 미치는 요인은 핵심기본간호술 수행자신감으로 31.2%의 설명력을 보였다. 이러한 결과는 간호대학생의 임상수행능력을 높이기 위해 간호대학생의 핵심기본간호술 수행자신감을 높일 수 있는 다양한 교육과정 개발이 필요함을 보여주는 것이라 하겠다.

• Clinical and Experimental Pediatrics
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• 제53권10호
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• pp.913-916
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• 2010

Congenital factor VII deficiency is a rare autosomal-recessive bleeding disorder. Bleeding manifestations and clinical findings vary widely, ranging from asymptomatic subjects to patients with hemorrhages that may cause significant handicaps. Treatment has traditionally involved factor VII(FVII) replacement therapy using fresh frozen plasma, prothrombin complex concentrates or plasma-derived FVII concentrates. Recombinant activated FVII ($NovoSeven^{(R)}$) is currently considered the first-line treatment for replacement therapy of FVII deficiency. Here we present a case of severe intracerebral and intraventricular hemorrhage in a neonate with congenital FVII deficiency.

• Biomolecules & Therapeutics
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• 제2권1호
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• pp.77-81
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• 1994

The acute toxicity of recombinant human epidermal growth factor, DWP-401 was evaluated in ICR mice of both sexes. Six groups of mice were administered orally or subcutaneously with 0, 0.125, 0.25, 0.5, 1 and 2 mg/kg of DWP-401. Abnormal clinical signs related to the compound were not observed, and no deaths occurred. Gross findings of necropsy revealed no evidence of specific toxicity related to DWP-401. LD$_{50}$ values for both male and female mice were evaluated to be over 2 mg/kg, which is approximately 2, 000 fold of presumed clinical dose.e.

• Clinical and Experimental Pediatrics
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• 제59권6호
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• pp.271-275
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• 2016

Purpose: A limited number of studies have examined the link between F-wave abnormalities and clinical presentation in pediatric Guillain-$Barr{\acute{e}}$ syndrome (GBS). Therefore, this study examined the importance of F-wave abnormalities as a prognostic factor in pediatric GBS patients. Methods: The records and electrodiagnostic studies (EDS) of 70 GBS patients were retrospectively evaluated, and divided into 2 groups according to the results of EDS. Group A (n=33) presented with F-wave abnormalities, and group B (n=26) exhibited normal findings. We compared laboratory reports, clinical features, response to treatment, and prognosis between the 2 groups. Results: Motor weakness was the most frequently observed symptom for either group. Clinically, the incidence of fever and upper respiratory symptoms differed between the 2 groups, while the prevalence of abnormal deep tendon reflex (DTR) was significantly higher in group A than B (P<0.05). Patients diagnosed with GBS had received intravenous immunoglobulin treatment: 94% in group A and 58% in group B. Furthermore, significantly greater numbers of patients in group A showed H-reflex abnormalities and poor prognosis compared with group B (P<0.05). Conclusion: This study demonstrated that F-waves are a clinically important prognostic factor in GBS. F-wave abnormalities were associated with abnormal DTR and poor prognosis in patients. Limited studies have examined the link between F-wave abnormalities and clinical results; therefore, further randomized controlled studies are needed to confirm the clinical characteristics and efficacy of treatments.

• Journal of Korean Dental Science
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• 제16권2호
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• pp.172-181
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• 2023

Purpose: To investigate the effect of epidermal growth factor (EGF) with collagen matrix (CM) for increasing gingival thickness. Materials and Methods: In five mongrel dogs, bilateral gingival defects were surgically made on the maxillary canines. After two months, either a subepithelial connective tissue graft (group SCTG) or CM with EGF (0.1 ug/ml, group EGF) was grafted, and the flap was coronally positioned to cover the graft materials. The animals were sacrificed after three months. Intraoral scanning was performed for soft tissue analysis. Histologic and histomorphometric analyses were performed. Result: Two animals exhibited wound dehiscence during the healing phase, leaving three for analysis. No statistically significant difference was found in soft tissue changes (P>0.05). The level of gingival margin (GM) increased in both groups (1.02±0.74 mm in group SCTG vs. 1.24±0.83 mm in group EGF). Linear increases at the GM pre-augmentation in the soft tissue profile were 1.08±0.58 mm in group SCTG and 0.96±0.73 mm in group EGF. Histomorphometric parameters (keratinized tissue height, tissue thickness, and rete peg density) were not significantly different between the groups (P>0.05). Conclusion: EGF loaded onto CM led to comparable gingival phenotype enhancement to SCTG.

• Physical Therapy Rehabilitation Science
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• 제13권1호
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• pp.71-77
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• 2024

Objective: The purpose of this study is to present practice guidelines on what physical therapy students must learn during clinical training and how to evaluate them. Design: Design & development research Methods: A Delphi survey was conducted with 16 experts. Experts who participated in the study were asked to respond to 15 musculoskeletal system, 14 nervous system, and 12 physical factor therapy items through an online survey with a 5-point Likert score for each item regarding suitability and importance. Results: As a result of defining the core basic physical therapy skills that students in the Department of Physical Therapy must learn through clinical practice and in the process of evaluating them, there was a strong opinion that among the specific fields of physical therapy, evaluation items related to the musculoskeletal system, nervous system, and cardiorespiratory system were important. On the contrary, physical factor therapy showed poor results. Conclusions: In a previous study, opinions on the specialty of physical therapists were collected from current physical therapists, and the field of physical factor therapy was evaluated low. I think this reflects the perception that treatment using electricity has been commonly used in the field of physical therapy for a long time and does not require deep expertise among clinicians. Physical therapy clinical practice guidelines and efficient operation plans for clinical practice were presented. Through this, it can be usefully applied in hospitals where physical therapy students undergo clinical training in the future.

• 보건의료산업학회지
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• 제8권4호
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• pp.149-161
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• 2014

The purpose of this study was to identify the association of factors related to clinical practice training for clinical competence among nursing students, and to analyze those factors influencing clinical competence, providing recommendations for improving their clinical competence and clinical learning environment. This descriptive correlative study completed organized questionnaires from 557 nursing students. The data was analyzed by SPSS 19.0. The most important factor affecting the clinical competence among nursing students was teaching effectiveness (${\beta}=.22$). followed by critical thinking (${\beta}=.19$). and the professional self-concept (${\beta}=.19$). The explained variable for clinical competence was 45.2% in nursing students. Thus, the development of an effective clinical internship program is important for strengthening nursing students' clinical competence. We suggest that the capability of nursing students should be strengthened and effective clinical internship programs should be developed to improve the clinical competence of nursing students.

• 한국임상약학회지
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• 제18권2호
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• pp.75-83
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• 2008

Purpose: Currently lung cancer ranks second in cancer for incidence rate and is a disease that ranks first for a death rate by cancerous growth because it is already advanced at the time of diagnosis. The purpose of this paper was to analyze the factors that affect the effectiveness of and rash occurrence by Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor (EGFR TKI) in patients with non-small cell lung cancer. Methods: A retrospective chart review of 100 patients, who took EGFR TKI (erlotinib, gefitinib) among patients who were diagnosed with non-small cell lung cancer in a Hospital in Korea between May 2005 and February 2008, was conducted. The drug effectiveness was evaluated by Response Evaluation Criteria In Solid Tumor. Results: EGFR mutation was the only factor associated with drug response (complete response and partial response). When stable disease was added to drug response as the evaluation parameter, ECOG and rash as well as EGFR mutation were found to be important factors. Survival, however, was not affected by EGFR mutation. The factors influenced on survival were older age (${\geq}65$), low ECOG ($1{\sim}2$), adenocarcinoma and rash. In the case of rash, group with EGFR mutation or low ECOG showed significantly higher chance of occurrence. There was no significant difference in rash occurrence between gefitinib and erlotinib groups. Conclusions: Based on the results, EGFR mutation positive and low ECOG ($1{\sim}2$) were significantly important factors for both effectiveness of EGFR TKI and rash occurrence. Also, rash itself was found to be an independently significant factor for the disease control and survival. Therefore, while administering EGFR TKI, patients who have the factors associated with rash occurrence should be closely monitored for effective and safe drug therapy.

• 한국콘텐츠학회논문지
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• 제13권1호
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• pp.311-321
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• 2013

본 연구는 학제별 간호대학생의 임상실습만족도를 확인하고, 임상실습만족도에 영향을 미치는 요인을 파악하여 비교하기 위해 두 도시의 1개 전문대학 간호과와 2개 대학교 간호학과에 다니는 2~4학년생 420명을 대상으로 자존감, 자기효능감, 대인관계, 전공만족도 및 임상실습만족도에 대한 설문지를 작성하도록 하였고, 기술 통계, t-test, one-way ANOVA, Pearson correlation coefficient, Hierarchical multiple regression으로 분석하였다. 연구 결과 3년제와 4년제 간호대학생의 임상실습만족도는 자존감, 자기효능감, 대인관계, 전공만족도와 유의한 순 상관 관계가 있었다. 3년제 간호대학생의 임상실습만족도에 영향을 미치는 요인은 전공만족도였고, 26.8%를 설명하였으며, 4년제 간호대학생의 임상실습만족도에 영향을 미치는 요인은 전공만족도와 대인관계 및 성별이었고, 31.9%를 설명하였다. 결론적으로 간호대학생의 임상실습 만족도를 높이기 위해서 전공만족도와 대인관계 등의 영향 요인을 기초로 한 중재 프로그램 개발이 필요하다.