• Title/Summary/Keyword: Clinical Manifestation

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Review of Cytokines for Nursing Research (사이토카인을 활용한 간호학 연구방향에 대한 고찰)

  • Shin, Gi-Soo;Lee, Kung-Suk;Jeong, Jae-Sim
    • Journal of Korean Biological Nursing Science
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    • v.9 no.2
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    • pp.153-158
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    • 2007
  • Purpose: Cytokines have widespread and potent effects across the life span. This study was carried out to understand about cytokines that influence nursing research and practice. Method: Journal publications rewied include cytokine topics on CINAHL and Korean nursing research from January 2000 to December 2006. Result: In this study, the specific and numerical expression of for the level of Cytokines as a physiological factor related to the disease clearly provides the patient's disease mechanism and manifestation of the symptoms. Also, it can be the basise of nursing research and evidence-based nursing intervention. Conclusion: The practical use of Cytokines has to be considered to set up the direction of the nursing research and the study of the standard manual of Cytokines is continuously required.

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Cytologic Diagnosis of Metastatic Hepatocellular Carcinoma by Aspiration Cytology of Sacrum (천골의 세침흡인검사로 진단된 전이성 간세포암종)

  • Shim, Jung-Weon;Ko, Ill-Hyang
    • The Korean Journal of Cytopathology
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    • v.1 no.2
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    • pp.179-184
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    • 1990
  • Bone metastasis of hepatocellular carcinoma appears to be peculiar when clinical manifestation of liver disease is not apparent, and initial diagnosis of metastatic hepatocellular carcinoma by fine needle aspiration cytology is rarely obtained. We experienced a case of 45-year-old man with metastatic hepatocellular carcinoma in the sacrum, which was diagnosed by fine needle aspiration cytology. The intrahepatic mass, measuring 1.2 cm in diameter and kept unchanged in size for two years, was never proved to be hepatocellular carcinoma histopathologically. The aspirated neoplastic cells were mostly in sheets, showing abundant acidophilic cytoplasm and large, round, centrally located nuclei with single, prominent acidophilic mucleoli. In the cell block section, diagnosis of metastatic well-differentiated hepatocellular carcinoma was made without difficulty, and definite trabecular fashion with sinusoidal endothelial cell lining was found.

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Pediatric Dysphagia (기질적 섭식장애)

  • Kim, Min-Young
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • v.12 no.sup1
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    • pp.77-84
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    • 2009
  • Pediatric dysphagia comes from disturbances in swallowing process, which has 'preparatory phase', 'oral phase', 'pharyngeal phase', and 'esophageal phase', and mainly the causes are neuro-muscular discoor-dination. It is necessary to recognize clinical manifestation if they have accompanied organic disorder and diagnose accurately. Videofluoroscopic study evaluation is a valuable method to find out abnormal swallowing mechanism at each phases. Treatment should be diagnosis specific, and multidisciplinary team approach is desirable. We can use various behavioral techniques to facilitate normal swallowing mechanism including conditioning of oral and pharyngeal structures, bolus manipulation, postural compensation, and adaptive feeding utensils. Important point is that the diagnosis and treatment for pediatric dysphagia should not be delayed because children are under development.

A case of Merkel cell carcinoma of the head and neck

  • Suk, Sangwoo;Shin, Hyun Woo;Yoon, Kun Chul
    • Archives of Craniofacial Surgery
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    • v.20 no.6
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    • pp.401-404
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    • 2019
  • Merkel cell carcinoma (MCC) is a relatively rare and aggressive cutaneous neuroendocrine malignancy. It is characterized by high rates of recurrence and metastasis, both to regional lymph nodes and to distant locations. Its characteristic clinical manifestation is a single, painless, hard, erythematous nodule on a sun-exposed area, particularly in older men. Surgical management of both the primary site and the sentinel lymph node is the standard of care. In this article, we describe the diagnosis and treatment of a case of MCC in the left cheek.

Radiation Induced Cystitis and Proctitis - Prediction, Assessment and Management

  • Mallick, Supriya;Madan, Renu;Julka, Pramod K;Rath, Goura K
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.14
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    • pp.5589-5594
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    • 2015
  • Cystitis and proctitis are defined as inflammation of bladder and rectum respectively. Haemorrhagic cystitis is the most severe clinical manifestation of radiation and chemical cystitis. Radiation proctitis and cystitis are major complications following radiotherapy. Prevention of radiation-induced haemorrhagic cystitis has been investigated using various oral agents with minimal benefit. Bladder irrigation remains the most frequently adopted modality followed by intra-vesical instillation of alum or formalin. In intractable cases, surgical intervention is required in the form of diversion ureterostomy or cystectomy. Proctitis is more common in even low dose ranges but is self-limiting and improves on treatment interruption. However, treatment of radiation proctitis is broadly non-invasive or invasive. Non-invasive treatment consists of non-steroid anti-inflammatory drugs (NSAIDs), anti-oxidants, sucralfate, short chain fatty acids and hyperbaric oxygen. Invasive treatment consists of ablative procedures like formalin application, endoscopic YAG laser coagulation or argon plasma coagulation and surgery as a last resort.

Manifestation and treatment in a cleidocranial dysplasia patient with a RUNX2 (T420I) mutation

  • Lee, Chaky;Jung, Hee-sup;Baek, Jin-A;Leem, Dae Ho;Ko, Seung-O
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.37
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    • pp.41.1-41.6
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    • 2015
  • Cleidocranial dysplasia is an autosomal dominant heritable skeletal disorder. The characteristic features of cleidocranial dysplasia (CCD) may include hypoplasia of the clavicle, delayed closure of frontanelles, late tooth eruption, and other skeletal disorders. This case report describes clinical and radiographic manifestations at the age of 11 and 29 of a CCD patient, investigates the mutation of core-binding factor A1 (CBFA1) based on gene analysis, and illustrates successful oral reconstruction with fixed prosthesis and dental implant after the extraction of multiple teeth.

Ischemic Stroke after Use of Cannabis: a Case Report and Review of Literature

  • Jung, Jo Sung;Park, Yae Won;Lee, Seung Ah;Song, Tae Jin;Lim, Soo Mee
    • Investigative Magnetic Resonance Imaging
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    • v.22 no.3
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    • pp.168-171
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    • 2018
  • Cannabis or marijuana is the most commonly used recreational drug after alcohol in the world, and usage is generally recognized as having few serious adverse effects. However, usage is restricted in South Korea. The report of ischemic stroke associated with cannabis is rare in literature. We present a case of a 47-year-old female patient with no underlying disease presenting with acute ischemic stroke after smoking cannabis in South Korea. The result for synthetic cannabinoid metabolites (delta-9 tetrahydrocannabinol) screening was positive. Absence of other vascular risk factors and drug screening results suggest a causal role of cannabis in this ischemic stroke case. The patient eventually progressed to brain death. The underlying mechanism, clinical manifestation, and imaging findings of cannabis-related stroke will be reviewed.

A Clinical Case of Dermatomyositis Complicated by Henoch-Schonlein Purpura (피부근염에 이환되었던 환아의 Henoch-Schonlein 자반증 증례 1례)

  • 홍상훈;김성환
    • The Journal of Korean Medicine
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    • v.23 no.2
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    • pp.225-230
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    • 2002
  • Dermatomyositis is an inflammatory cutaneo-muscular disease of unknown etiology, characterized by symmetrical proximal muscle weakness and typical dermatologic manifestation. Henoch-Schonlein purpura is most common in children. In Korea, dermatomyositis or Henoch-Schonlein purpura associated with herbal medicine has not been reported. The subject patient is a seven year-old girl diagnosed with dermatomyositis in August 1999 and Henoch-Schonlein purpura in January, July 2001. There were symptoms of dermatomyositis such as headache, arthralgia, eruption, itching and abdominal pain. I think the herb-prescription composed or Radix astragali (Huangqi), Herba agrimoniae (Xianhecao), Fructus jujubae (Dazao) had an ameliorating effect on Henoch-Schonlein purpura by decreasing these symptoms.

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A Case of Sandifer Syndrome (Sandifer 증후군 1례)

  • Lee, Mira;Kim, Soo Hyun;Kim, Yong Joo;Seol, In Joon
    • Clinical and Experimental Pediatrics
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    • v.46 no.10
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    • pp.1036-1039
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    • 2003
  • Sandifer syndrome is a rare manifestation of gastroesophageal reflux in children, occurring in association with abnormal movement of the head and neck and recurrent episodes of seizure after feeding. This syndrome may be misdiagnosed as infantile seizure and musculoskeletal disorder and may be associated with failure to thrive, anemia, aspiration pneumonia, and esophagitis. In this paper, Sandifer syndrome in a four months old male with recurrent aspiration pneumonia, apnea, and seizure after feeding is presented.

Right Diaphragmatic Injury Accompanied by Herniation of the Liver: A Case Report

  • Lee, Min A;Choi, Kang Kook;Lee, Gil Jae;Yu, Byung Chul;Ma, Dae Sung;Jeon, Yang Bin;Lee, Jung Nam;Chung, Min
    • Journal of Trauma and Injury
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    • v.29 no.2
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    • pp.43-46
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    • 2016
  • Traumatic diaphragmatic injury (TDI) occurs in 1% of patients of blunt abdominal trauma. Most TDIs involve the left diaphragm, however the authors experienced TDI accompanied by a liver laceration of the right diaphragm. When detected early, TDI can be easily treated, however serious complications can occur if not. When diaphragmatic injury is suspected due to clinical manifestation, comprehensive analysis of the patient data including radiologic findings is important.