• CELLMED
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• v.3 no.2
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• pp.18.1-18.7
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• 2013

Inflammation in rheumatoid arthritis is characterized by immune cell infiltration and cytokine secretion. In particular, mast cells and their cytokines play an important role in the pathogenesis of rheumatoid arthritis. Korean medicine, BaekJeol-Tang (BT) was designed by traditional Korean medicine theory. We already reported therapeutic effect of BT in rheumatoid arthritis. Here, we report the specific underlying mechanism of BT in activated human mast cells, HMC-1 cells. In addition, we report for the first time that BT significantly inhibited the production and mRNA expression of proinflammatory cytokines including thymic stromal lymphopoietin, interleukin (IL)-$1{\beta}$, IL-6, IL-8, and tumor necrosis factor-${\alpha}$ in activated HMC-1 cells. BT also decreased the activation of mitogen-activated protein kinases, nuclear factor-${\kappa}B$, and caspapase-1. Taken together, these results indicate that BT has potential as a regulator of inflammatory reactions for the treatment of arthritis such as osteoarthritis and rheumatoid arthritis.

• Archives of Plastic Surgery
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• v.42 no.6
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• pp.803-805
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• 2015

• Korean Circulation Journal
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• v.48 no.12
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• pp.1160-1162
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• 2018

• Journal of Korean society of Dental Hygiene
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• v.10 no.3
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• pp.495-502
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• 2010

Objetives : It tries to grasp whether the knowledge and attitude about the oral health of the school dental clinic operation school and non-operation school with 6 grade children in Daejeon Metropolitan City and the school dental clinic operation reaches any influence to the oral health of the child or not. Methods : The self-administered survey was performed for the school dental clinic operation group (201 people) and non-operation group (207 people) child 408 people from October 5th in 2009 until October 31st. By using the spss statistical program(VER 15.0), the statistical analysis performed the chi-square verification and t-test. Results : 1. The knowledge degree about the oral health according to the oral health education is the health education experienced group $22.34{\pm}3.36$ and non-experienced group $20.32{\pm}3.49$ (p=0.000), and the attitude showed the health education experienced group $15.06{\pm}2.99$ and non-experienced group $13.30{\pm}3.20$, oral health education experienced group significantly higher in the knowledge and the attitude, there was statistically significant difference(p=0.000). 2. The knowledge degree about the oral health according to the school dental clinic operation is school dental clinic group $22.84{\pm}2.92$ and non-school dental clinic group $20.83{\pm}3.73$ (p=0.000), and attitude showed high the school dental clinic group as the school dental clinic group $15.48{\pm}2.75$ and non-school dental clinic group $13.76{\pm}3.26$, there was statistically significant difference (p=0.000). Conclusions : The knowledge degree and attitude about the oral health showed high in oral health education experience group and the school dental clinic group when looking at the result described in the above. It thinks that the school dental clinic group has to be expanded for the oral health promotion of the children.

• Journal of Korean Public Health Nursing
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• v.22 no.1
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• pp.62-73
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• 2008

Purpose: To examine the outcomes of a smoking cessation clinic at a public health center, in Hwasung city in 2006 and to examine the perceptions of the users regarding the clinic services. Method: 620 smokers who visited the smoking cessation clinic from January, 2006 to November, 2006 were enrolled. An instrument developed by the researcher was used to collect their perceptions. The instrument comprised 24 questions, on a 5-point Likert scale investigating the clinic services in terms of counseling time, environment, readiness of the counselors, counseling information, campaign method, medication use, and follow-up services. The general characteristics of the participants were collected from the database developed by the Ministry of Health & Welfare. The data were analyzed with frequencies, percentage, mean and standard deviation methods. Results: The outcomes of the smoking cessation clinic in Hwasung city in 2006 showed some limitations in terms of low-income group, female smokers, and young adult smokers. Conclusion: Strategies for solving these limitations were necessary to increase the effectiveness of the smoking cessation clinic. Clinic services focused on cognitive-behavioral therapy needed to be developed in accordance with chemotherapy. More effective publicizing campaigns of the clinic services also needed to be developed for more people to know about the clinic. Strategies to increase the accessibility for the people living far from the clinic were also necessary. Assessment of the smokers who did not visit clinic was also recommended in order to determine their intentions, or barriers to visit the clinic.

• The Journal of the Korean dental association
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• v.56 no.12
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• pp.658-666
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• 2018

This study analyzes 21,686 dental clinic business names from 1946 to February 2016, where official records exist. The results of this study will be used as a historical data of Korean dental clinic and contribute to the decision of dental clinic name. According to the results of analysis, the first official dental clinic used in Korea was 'Chu' in 1946, 'Minsaeng' and 'Chusaeng' in 1958, and "Won" in 1959. In the 1960s, dentists' family names were often used as dental clinics. In the 1970s, dental clinic names were often used as dentists' family name, 'Jung-ang' and 'Seongsin'. In the 1980s, dental clinic name was used more than other names such as 'Seoul', 'Yonsei', 'Hyundai' and 'Sang-a' along with the dentist's family name. In the 1990s, a dental clinic name was used to refer to the words 'Yeonsei', 'Seoul', 'Hyundai', 'Sang-a', 'Isalang', 'Uli', 'Jeil', 'Bubu' used a lot. In the 2000s, Dental Clinic's name began to use english words such as $^{\circ}{\AE}Good$ Morning','White','Prime 'and adjectives such as 'Haengboghan', 'Ipyeonhan'. The characteristic of the dental clinic name in 2010 is the increase of the business name 'UD'. From 1946 to February 2016, the most commonly used dental clinic name was 'Seoul', 'Uri', 'Isarang', 'Yonsei', 'Hyundai', 'Good Morning' 'Jung-ang', 'UD', 'I', 'Miso'.

• The Korean Journal of Pain
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• v.18 no.2
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• pp.146-150
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• 2005

Background: Recently, the number of patients visiting pain clinics has been increasing with the augmented concerns of those patients about the management of their pain. We conducted this study in order to elucidate the characteristics of patients visiting pain clinics and to determine a method to further raise their awareness about pain treatment. Methods: We reviewed 1,424 new patients who visited our pain clinic from March 2003 to December 2004. We analyzed these patients according to their age and sex, treatment method before visiting the pain clinic, coexisting disease, chief complaint and pain location, resident district, route of visiting pain clinic, and degree of impairment due to pain by use of questionnaire. Results: In age distribution, the largest proportion (23.5%) was in their 50's. Most patients (64.0%) had received treatment in an oriental medicine clinic before visiting the pain clinic. The most common coexisting disease was hypertension (20.3%) and low back pain was the most common chief complaint (68.3%). Most of the patients lived in Gyeonggido (87%) and most visited our pain clinic on the recommendation of other patients who had visited our pain clinic before. Conclusions: We need to guide pain patients to undergo proper treatment much earlier using patient education or a referral system. Moreover, we should be more careful in patients with diabetes mellitus, and should have greater concern in the treatment of low back pain.

• Korean Journal of Health Education and Promotion
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• v.27 no.2
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• pp.151-163
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• 2010

Objectives: This study was conducted to analyze problems and priority of university health services through analysis of health promotion programs and administrative system of university health clinics. Methods: In first telephone survey, 349 colleges and universities nationwide were surveyed to find out whether they operate health clinic or not. The administrative system and health promotion services of university health clinics were analyzed in 198 schools which had health clinic in it. Results: 160 schools were included in the final analysis. The most common name of university health clinic was 'health clinic' (35.2%), and heads of 52 university health clinics were non-medical school professors. 20.9% of the school provided details of the rules and implement guidelines of health care service. Health promotion services of university health clinic were set the non-smoking area (90.6%), health counseling (81.8%), providing health information (74.8%), health check-up (65.4%), health education (61.4%), partnership with health institutions in a community (61.4%), and immunization (48.1%) in order of that. Conclusion: It is urgent to establish the regulatory and guidelines for university health clinic. Each member of school should have interests in their health clinic and acknowledge health promotion services which they can get at the university health clinic.

• 대한생식의학회:학술대회논문집
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• 2001.06a
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• pp.41.2-42
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• 2001

• The Korean Journal of Pain
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• v.8 no.2
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• pp.363-366
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• 1995

Blockade of the ganglion impar was performed as an alternertive means of managing intractable neoplastic perineal pain of sympathetic origin. We successively treated a patient who had suffered from excessive perianal sweating with ganglion impar block using pure alcohol. Eight months after block, the patient has no complaint of perianal sweating. Ganglion impar block is an effective method in the treatment of excessive perianal sweating as well as perineal pain of sympathetic origin.