• 대한치매학회지
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• 제17권4호
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• pp.156-162
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• 2018

Background and Purpose: Previous studies have reported conflicting results about the prevalence of seizures in Alzheimer's disease (AD). There are few epidemiological studies on this topic in Asia. Thus, the objective of this study was to examine demographic and clinical characteristics as well as incidence for seizures in AD patients compared to non-AD patients in a prospective, longitudinal, community-based cohort with a long follow-up. Methods: Data were collected from National Health Insurance Service-National Elderly Cohort (NHIS-elderly) Database to define patients with AD from 2004-2006 using Korean Classification Diseases codes G30 and F00. We performed a 1:5 case-control propensity score matching based on age, sex, and household income. We conducted Cox proportional hazards regression analysis to estimate the risk of epilepsy in AD patients. Results: In the cohort study, patients with AD had higher risk for epilepsy than those without AD, with hazard ratio of 2.773 (95% confidence interval [CI], 2.515-3.057). This study also showed that male gender and comorbidities such as hypertension, hyperlipidemia, diabetes, and chronic kidney disease increased the risk of developing epilepsy. Patients with AD had 1.527 (95% CI, 1.375-1.695) times higher mortality rate than those in the control group. Conclusions: AD patients have significantly higher risk of developing epilepsy than non-AD patients.

• 한국건설관리학회논문집
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• 제20권3호
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• pp.86-96
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• 2019

한국 고유의 목조건축형태인 한옥을 현대 공법 및 재료 등의 기술의 적용을 통해 품질과 시공성을 향상시키고, 다양한 규모와 시설을 포괄한 신한옥의 형태로 보급 확산하려는 노력이 계속되어 왔다. 본 연구는 신한옥 표준분류체계(Hanclass) 적용을 통해 구축된, 일곱 개의 실증구축사업 사업비 정보를 분석하여 신한옥 공법변화의 추세와 함께 이에 따른 공사비 변화를 고찰하였다. 우선, 일곱 개 실증구축사례의 공법 특징을 분석하고, 이를 공종분류, 재료분류, 공법분류, 부위분류를 분석의 기준으로 설정하여 공사비에 끼치는 영향을 분석하였다. 또한 사례 프로젝트들에서의 공법 변화 주요 영향요인들을 항목화하고 연계된 비용변화를 정량화함으로써 향후 지속적인 공법과 비용간의 관계를 관찰하기 위한 기본 구조를 작성하였다. 본 연구의 결과는 지속적으로 개발되고 있는 신한옥의 신공법의 추세를 체계적으로 파악하고 또한 발전방향의 가이드를 할 것으로 기대한다.

• 한국환경과학회지
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• 제28권4호
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• pp.441-454
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• 2019

The present study analyzes the characteristics of 43 typhoons that affected the Korean Peninsula between 2002 and 2015. The analysis was based on 3-second gust measurements, which is the maximum wind speed relevant for typhoon disaster prevention, using a typhoon disaster prevention model. And the distribution and characteristics of the 3-second gusts of four typhoons, RUSA, MAEMI, KOMPASU, and BOLAVEN that caused great damage, were also analyzed. The analysis show that between May and October during which typhoons affected the Korean Peninsula, the month with the highest frequency was August(13 times), followed by July and September with 12 occurrences each. Furthermore, the 3-second gust was strongest at 21.2 m/s in September, followed by 19.6 m/s in August. These results show that the Korean Peninsula was most frequently affected by typhoons in August and September, and the 3-second gusts were also the strongest during these two months. Typhoons MAEMI and KOMPASU showed distribution of strong 3-second gusts in the right area of the typhoon path, whereas typhoons RUSA and BOLAVEN showed strong 3-second gusts over the entire Korean Peninsula. Moreover, 3-second gusts amount of the ratio of 0.7 % in case of RUSA, 0.8 % at MAEMI, 3.3 % at KOMPASU, and 21.8 % at BOLAVEN showed as "very strong", based on the typhoon intensity classification criteria of the Korea Meteorological Administration. Based on the results of this study, a database was built with the frequencies of the monthly typhoons and 3-second gust data for all typhoons that affected the Korean Peninsula, which could be used as the basic data for developing a typhoon disaster prevention system.

• 한국산업보건학회지
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• 제31권2호
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• pp.147-155
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• 2021

Objective: The purpose of this study was to find ways for strengthening occupational health services through monitoring exposure to health hazards. Methods: About 70,000 workplaces that have conducted the work environment measurement(WEM) over the last three years(2017~2019) were classified according to the Korean Standard Industry Classification(KSIC), and the current status of WEM by industry was analyzed. The authors considered ways to monitor exposure to health hazards in order to strengthen occupational health services and protect workers' health. Results: Based on the KSIC, 934 of the 1,196 total sub-classified industries have conducted WEM in at least one workplace over the last three year(2017~2019). In the case of manufacturing, out of a total of 477 sub-classified industries, 474 have conducted WEM at more than one workplace. However, in some industries, WEM was not conducted or the implementation rate was low, so it was necessary to examine whether WEM should be expanded based on a detailed analysis of the WEM database. To this end, it is necessary to form an exposure monitoring committee in which various experts from different fields can participate. The committee needs to discuss the overall matters necessary for selecting industries that require detailed investigation or research, review the results, and prepare a final recommendation. Conclusion: In conclusion, the government needs to come up with a plan to strengthen occupational health services through surveys and research on the current status of WEM and work environment management models by industry.

• 한방안이비인후피부과학회지
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• 제34권2호
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• pp.21-37
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• 2021

Objectives : Allergic rhinitis(AR) is a common chronic disease that accounts for 10-40% of the world's population. This study aims to analyze the status of claims, prevalence, and medical utilization of allergic rhinitis patients using representative patients sample data. Methods : This study used the National Patients Sample(HIRA-NPS) of the Health Insurance Review and Assessment Service for 7 years(2010-2016). And we defined AR patients as all statements including J30 or a subcategory of J30 as the main disease, using the Korean Standard Classification of Diseases(KCD-7). The trend of AR patients by year was divided into Western medicine(WM) and Korean medicine(KM), and analyzed by subgroup analysis such as inpatient/outpatient, gender, age, insurance type, and care institution. Results : Patients with AR were mainly claimed for first sub diagnosis in WM and major diagnosis in KM, and the number of claims increased about 1.3 times and 1.4 times compared to 2010 in WM and KM, respectively. In addition, the total annual medical expenses in 2016 increased 1.3 times and 1.7 times compared to 2010, respectively. Conclusions : Both WM and KM are showing a steadily increasing trend in medical use due to allergic rhinitis. Further research is needed by considering genetic and environmental factors and individual characteristics, and linking with additional data.

• 한국융합학회논문지
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• 제12권1호
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• pp.49-55
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• 2021

최근에는 데이터베이스의 발달로 금융, 보안, 네트워크 등에서 생성된 많은 데이터가 저장 가능하며, 기계학습 기반 분류기를 통해 분석이 이루어지고 있다. 이 때 주로 야기되는 문제는 데이터 불균형으로, 학습 시 다수 범주의 데이터들로 과적합이 되어 분류 정확도가 떨어지는 경우가 발생한다. 이를 해결하기 위해 소수 범주의 데이터 수를 증가시키는 오버샘플링 전략이 주로 사용되며, 데이터 분포에 적합한 기법과 인자들을 다양하게 조절하는 과정이 필요하다. 이러한 과정의 개선을 위해 본 연구에서는 스모트와 생성적 적대 신경망 등 다양한 기법 기반의 오버샘플링 조합과 비율을 유전알고리즘을 통해 탐색하고 최적화 하는 전략을 제안한다. 제안된 전략과 단일 오버샘플링 기법으로 신용카드 사기 탐지 데이터를 샘플링 한 뒤, 각각의 데이터들로 학습한 분류기의 성능을 비교한다. 그 결과 유전알고리즘으로 기법별 비율을 탐색하여 최적화 한 전략의 성능이 기존 전략들 보다 우수했다.

• 정보보호학회논문지
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• 제17권2호
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• pp.29-40
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• 2007

입력이 되는 지문 영상의 품질은 지문 인식 시스템의 전체 인식 성능에 다양하게 영향을 미친다. 지문 영상의 품질은 추출, 정합 등의 알고리즘 내에서도 중요한 정보로 활용되는데, 특히 센서 입력부에서의 품질 측정 및 평가는 불필요한 처리 과정을 줄여 시스템의 전반적인 안정성을 유도하는데 사용되는 만큼 매우 중요한 과정이 된다. 본 논문에서는 기존의 많은 연구 결과들과는 달리 센서, 인식 알고리즘, 손가락의 특성에 독립적인 지문 영상 품질을 정의하였다. 또한 이의 측정을 위하여 지문 영상의 지역적 특성들만을 이용한 새로운 품질 측정 방법도 제안하였다. 제안하는 품질 측정 방법은 블록별 품질 특성 분류 결과를 이용하여 전체 지문 영상의 품질을 수치화하는 것으로, 본 논문에서는 FVC에서 사용된 몇 가지 서브 데이터베이스들을 이용하여 제안하는 방법의 유용함을 증명하였다. 실험 결과는 NIST의 NFIQ, AWARE사의 QualityCheck 품질 측정 알고리즘들과 비교되었는데, 이들 알고리즘들에 비해 제안하는 측정 방법이 인간의 시각적 분류 기준과 유사한 결과를 보였다.

• International Journal of Computer Science & Network Security
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• 제21권6호
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• pp.319-328
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• 2021

Parallel administration of numerous drugs increases Drug-Drug Interaction (DDI) because one drug might affect the activity of other drugs. DDI causes negative or positive impacts on therapeutic output. So there is a need to discover DDI to enhance the safety of consuming drugs. Though there are several DDI system exist to predict an interaction but nowadays it becomes impossible to maintain with a large number of biomedical texts which is getting increased rapidly. Mostly the existing DDI system address classification issues, and especially rely on handcrafted features, and some features which are based on particular domain tools. The objective of this paper to predict DDI in a way to avoid adverse effects caused by the consumed drugs, to predict similarities among the drug, Drug pair similarity calculation is performed. The best optimal weight is obtained with the support of KHA. LSTM function with weight obtained from KHA and makes bets prediction of DDI. Our methodology depends on (LSTM-KHA) for the detection of DDI. Similarities among the drugs are measured with the help of drug pair similarity calculation. KHA is used to find the best optimal weight which is used by LSTM to predict DDI. The experimental result was conducted on three kinds of dataset DS1 (CYP), DS2 (NCYP), and DS3 taken from the DrugBank database. To evaluate the performance of proposed work in terms of performance metrics like accuracy, recall, precision, F-measures, AUPR, AUC, and AUROC. Experimental results express that the proposed method outperforms other existing methods for predicting DDI. LSTMKHA produces reasonable performance metrics when compared to the existing DDI prediction model.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제25권1호
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• pp.61-69
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• 2022

Purpose: Studies in adults have shown an increasing incidence of Clostridioides difficile infection (CDI) in patients hospitalized with acute pancreatitis (AP). There is lack of epidemiological data on CDI and its impact on hospitalized pediatric patients with AP. Methods: We analyzed the National Inpatient Sample and Kids' Inpatient Database between the years 2003 and 2016 and included all patients (age <21 years) with a primary diagnosis of AP using specific International Classification of Diseases codes. We compared clinical outcomes between children with CDI and those without CDI. Our primary outcome was severe AP and secondary outcomes included length of stay and hospital charges. Results: A total of 123,240 hospitalizations related to AP were analyzed and CDI was noted in 0.6% of the hospital. The prevalence rate of CDI doubled from 0.4% (2003) to 0.8% (2016), p=0.03. AP patients with CDI had increased comorbidities, and also underwent more invasive surgical procedures, p<0.05. AP patients with CDI had a higher in-hospital mortality rate and increased prevalence of severe AP, p<0.001. Multivariate regression models showed that CDI was associated with 2.4 times (confidence interval [CI]: 1.91 to 3.01, p<0.001) increased odds of severe AP. CDI patients had 7.24 (CI: 6.81 to 7.67, p<0.001) additional hospital days while incurring $59,032 (CI: 54,050 to 64,014, p<0.001) additional hospitalization charges. Conclusion: CDI in pediatric patients with AP is associated with adverse clinical outcomes and increased healthcare resource utilization. Further studies are needed to elucidate this association to prevent the development of CDI and to improve outcomes.

• 한국기록관리학회지
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• 제22권1호
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• pp.237-243
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• 2022

성북마을아카이브는 성북구청과 성북문화원이 협력하여 지역의 고유성과 특수성을 담고자 구축한 마을아카이브이다. 공동체의 기록물을 보존하는 공동체 아카이브이자, 원천자료의 디지털화를 통해 데이터베이스를 구축해가는 디지털 아카이브이다. 민·관 거버넌스로 연차적·단계별 추진을 거쳐 관리시스템과 홈페이지를 구축하였다. 성북마을아카이브의 시스템은 고도화된 마을기록 표준분류체계를 바탕으로 자료축적과 개별 기록물 간의 연결이 원활히 이루어지도록 설계되었다. 성북문화원은 이를 바탕으로 기록물을 온·오프라인으로 연계하면서 융합문화콘텐츠를 생산하려고 노력하였다. 또한 기록물의 보존뿐 아니라 콘텐츠 생산 및 활용을 위해 홈페이지에 보여지는 항목 구성을 다양화했다. 성북의 역사문화자원을 어떻게 하면 이용자들에게 그 생성 및 존재를 맥락과 함께 보여줄 수 있을지에 대한 고민 끝에 만든 구조이다. 또한 다채로운 큐레이션과 주민기록단의 활동을 통해 보다 풍부한 아카이브 플랫폼을 구축하였다.